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Items: 1 to 50 of 360

1.

Automatic optic disc detection in colour fundus images by means of multispectral analysis and information content.

Martinez-Perez ME, Witt N, Parker KH, Hughes AD, Thom SAM.

PeerJ. 2019 Jun 27;7:e7119. doi: 10.7717/peerj.7119. eCollection 2019.

PMID:
31293825
Free PMC Article
3.

Ground Same Intratransport Efficacy as Air for Acute Aortic Diseases.

Rose M, Newton C, Boualam B, Hassan M, Bogne N, Mitchell J, Tanveer S, Tiffany L, Thom S, Tran QK.

Air Med J. 2019 May - Jun;38(3):188-194. doi: 10.1016/j.amj.2019.01.003. Epub 2019 Feb 12.

PMID:
31122585
4.

Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time.

Gu B, Piebalgs A, Huang Y, Longstaff C, Hughes AD, Chen R, Thom SA, Xu XY.

Pharmaceutics. 2019 Mar 7;11(3). pii: E111. doi: 10.3390/pharmaceutics11030111.

5.

An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy.

Huang Y, Yu L, Ren J, Gu B, Longstaff C, Hughes AD, Thom SA, Xu XY, Chen R.

J Control Release. 2019 Apr 28;300:1-12. doi: 10.1016/j.jconrel.2019.02.033. Epub 2019 Feb 23.

PMID:
30807804
6.

Microparticle-induced vascular injury in mice following decompression is inhibited by hyperbaric oxygen: effects on microparticles and interleukin-1β.

Thom SR, Bhopale VM, Yang M.

J Appl Physiol (1985). 2019 Apr 1;126(4):1006-1014. doi: 10.1152/japplphysiol.01109.2018. Epub 2019 Feb 14.

PMID:
30763157
7.

Assessing adequacy of emergency provider documentation among interhospital transferred patients with acute aortic dissection.

Rose M, Newton C, Boualam B, Bogne N, Ketchum A, Shah U, Mitchell J, Tanveer S, Lurie T, Robinson W, Duncan R, Thom S, Tran QK.

World J Emerg Med. 2019;10(2):94-100. doi: 10.5847/wjem.j.1920-8642.2019.02.005.

8.
9.

The Education and Practice Environment for Medical Radiation Science Professionals Caring for Lesbian, Gay, Bisexual, and Transgender Patients: An Analysis of a #MedRadJClub Tweet Chat.

Bolderston A, Watson J, Thom S, Meeking K.

J Med Imaging Radiat Sci. 2018 Dec;49(4):428-435.e1. doi: 10.1016/j.jmir.2018.10.006. Epub 2018 Nov 3. Erratum in: J Med Imaging Radiat Sci. 2019 Jun;50(2):348.

PMID:
30514561
10.

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL; Million Veteran Program, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ.

Nat Genet. 2018 Dec;50(12):1755. doi: 10.1038/s41588-018-0297-3.

11.

Computational Simulations of Thrombolytic Therapy in Acute Ischaemic Stroke.

Piebalgs A, Gu B, Roi D, Lobotesis K, Thom S, Xu XY.

Sci Rep. 2018 Oct 25;8(1):15810. doi: 10.1038/s41598-018-34082-7.

12.

Randomized Crossover Trial of the Impact of Morning or Evening Dosing of Antihypertensive Agents on 24-Hour Ambulatory Blood Pressure.

Poulter NR, Savopoulos C, Anjum A, Apostolopoulou M, Chapman N, Cross M, Falaschetti E, Fotiadis S, James RM, Kanellos I, Szigeti M, Thom S, Sever P, Thompson D, Hatzitolios AI.

Hypertension. 2018 Oct;72(4):870-873. doi: 10.1161/HYPERTENSIONAHA.118.11101.

13.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyllensten U, Hamsten A, Harris TB, Harris SE, Hartman CA, Havulinna AS, Hicks AA, Hofer E, Hofman A, Hottenga JJ, Huffman JE, Hwang SJ, Ingelsson E, James A, Jansen R, Jarvelin MR, Joehanes R, Johansson Å, Johnson AD, Joshi PK, Jousilahti P, Jukema JW, Jula A, Kähönen M, Kathiresan S, Keavney BD, Khaw KT, Knekt P, Knight J, Kolcic I, Kooner JS, Koskinen S, Kristiansson K, Kutalik Z, Laan M, Larson M, Launer LJ, Lehne B, Lehtimäki T, Liewald DCM, Lin L, Lind L, Lindgren CM, Liu Y, Loos RJF, Lopez LM, Lu Y, Lyytikäinen LP, Mahajan A, Mamasoula C, Marrugat J, Marten J, Milaneschi Y, Morgan A, Morris AP, Morrison AC, Munson PJ, Nalls MA, Nandakumar P, Nelson CP, Niiranen T, Nolte IM, Nutile T, Oldehinkel AJ, Oostra BA, O'Reilly PF, Org E, Padmanabhan S, Palmas W, Palotie A, Pattie A, Penninx BWJH, Perola M, Peters A, Polasek O, Pramstaller PP, Nguyen QT, Raitakari OT, Ren M, Rettig R, Rice K, Ridker PM, Ried JS, Riese H, Ripatti S, Robino A, Rose LM, Rotter JI, Rudan I, Ruggiero D, Saba Y, Sala CF, Salomaa V, Samani NJ, Sarin AP, Schmidt R, Schmidt H, Shrine N, Siscovick D, Smith AV, Snieder H, Sõber S, Sorice R, Starr JM, Stott DJ, Strachan DP, Strawbridge RJ, Sundström J, Swertz MA, Taylor KD, Teumer A, Tobin MD, Tomaszewski M, Toniolo D, Traglia M, Trompet S, Tuomilehto J, Tzourio C, Uitterlinden AG, Vaez A, van der Most PJ, van Duijn CM, Vergnaud AC, Verwoert GC, Vitart V, Völker U, Vollenweider P, Vuckovic D, Watkins H, Wild SH, Willemsen G, Wilson JF, Wright AF, Yao J, Zemunik T, Zhang W, Attia JR, Butterworth AS, Chasman DI, Conen D, Cucca F, Danesh J, Hayward C, Howson JMM, Laakso M, Lakatta EG, Langenberg C, Melander O, Mook-Kanamori DO, Palmer CNA, Risch L, Scott RA, Scott RJ, Sever P, Spector TD, van der Harst P, Wareham NJ, Zeggini E, Levy D, Munroe PB, Newton-Cheh C, Brown MJ, Metspalu A, Hung AM, O'Donnell CJ, Edwards TL, Psaty BM, Tzoulaki I, Barnes MR, Wain LV, Elliott P, Caulfield MJ; Million Veteran Program.

Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x. Epub 2018 Sep 17. Erratum in: Nat Genet. 2018 Dec;50(12):1755.

14.

Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.

Webster R, Salam A, de Silva HA, Selak V, Stepien S, Rajapakse S, Amarasekara S, Amarasena N, Billot L, de Silva AP, Fernando M, Guggilla R, Jan S, Jayawardena J, Maulik PK, Mendis S, Mendis S, Munasinghe J, Naik N, Prabhakaran D, Ranasinghe G, Thom S, Tisserra N, Senaratne V, Wijekoon S, Wijeyasingam S, Rodgers A, Patel A; TRIUMPH Study Group.

JAMA. 2018 Aug 14;320(6):566-579. doi: 10.1001/jama.2018.10359. Erratum in: JAMA. 2018 Nov 13;320(18):1940.

15.

Provocative decompression causes diffuse vascular injury in mice mediated by microparticles containing interleukin-1β.

Thom SR, Bhopale VM, Yu K, Yang M.

J Appl Physiol (1985). 2018 Aug 16. doi: 10.1152/japplphysiol.00620.2018. [Epub ahead of print]

PMID:
30113270
16.

Differential influence of vitamin C on the peripheral and cerebral circulation after diving and exposure to hyperoxia.

Barak OF, Caljkusic K, Hoiland RL, Ainslie PN, Thom SR, Yang M, Jovanov P, Dujic Z.

Am J Physiol Regul Integr Comp Physiol. 2018 Oct 1;315(4):R759-R767. doi: 10.1152/ajpregu.00412.2017. Epub 2018 Jul 11.

PMID:
29995458
17.

Reaching cardiovascular prevention guideline targets with a polypill-based approach: a meta-analysis of randomised clinical trials.

Selak V, Webster R, Stepien S, Bullen C, Patel A, Thom S, Arroll B, Bots ML, Brown A, Crengle S, Dorairaj P, Elley CR, Grobbee DE, Harwood M, Hillis GS, Laba TL, Neal B, Peiris D, Rafter N, Reid C, Stanton A, Tonkin A, Usherwood T, Wadham A, Rodgers A.

Heart. 2019 Jan;105(1):42-48. doi: 10.1136/heartjnl-2018-313108. Epub 2018 Jun 28.

18.

Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Single-Vessel Coronary Artery Disease.

Al-Lamee R, Howard JP, Shun-Shin MJ, Thompson D, Dehbi HM, Sen S, Nijjer S, Petraco R, Davies J, Keeble T, Tang K, Malik IS, Cook C, Ahmad Y, Sharp ASP, Gerber R, Baker C, Kaprielian R, Talwar S, Assomull R, Cole G, Keenan NG, Kanaganayagam G, Sehmi J, Wensel R, Harrell FE, Mayet J, Thom SA, Davies JE, Francis DP.

Circulation. 2018 Oct 23;138(17):1780-1792. doi: 10.1161/CIRCULATIONAHA.118.033801.

19.

Cost-effectiveness of a fixed dose combination (polypill) in secondary prevention of cardiovascular diseases in India: Within-trial cost-effectiveness analysis of the UMPIRE trial.

Singh K, Crossan C, Laba TL, Roy A, Hayes A, Salam A, Jan S, Lord J, Tandon N, Rodgers A, Patel A, Thom S, Prabhakaran D.

Int J Cardiol. 2018 Jul 1;262:71-78. doi: 10.1016/j.ijcard.2018.03.082. Epub 2018 Mar 21.

20.

A protocol for an economic evaluation of a polypill in patients with established or at high risk of cardiovascular disease in a UK NHS setting: RUPEE (NHS) study.

Crossan C, Dehbi HM, Williams H, Poulter N, Rodgers A, Jan S, Thom S, Lord J.

BMJ Open. 2018 Mar 14;8(3):e013063. doi: 10.1136/bmjopen-2016-013063. Review.

21.

Does advanced practice in radiography benefit the healthcare system? A literature review.

Thom SE.

Radiography (Lond). 2018 Feb;24(1):84-89. doi: 10.1016/j.radi.2017.08.002. Epub 2017 Sep 4. Review.

PMID:
29306381
22.

Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

McCarthy NS, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S, Hughes AD, Munroe PB, Howard P, Johnson T, Caulfield M, Shields DC, O'Brien E, Fitzgerald DJ, Stanton AV.

Atherosclerosis. 2018 Feb;269:42-49. doi: 10.1016/j.atherosclerosis.2017.12.013. Epub 2017 Dec 8.

23.

A qualitative study of the experience of lower extremity wounds and amputations among people with diabetes in Philadelphia.

Barg FK, Cronholm PF, Easley EE, Davis T, Hampton M, Malay DS, Donohue C, Song J, Thom SR, Margolis DJ.

Wound Repair Regen. 2017 Sep;25(5):864-870. doi: 10.1111/wrr.12593. Epub 2017 Dec 8.

PMID:
29220878
24.

Disturbed blood flow worsens endothelial dysfunction in moderate-severe chronic obstructive pulmonary disease.

Barak OF, Mladinov S, Hoiland RL, Tremblay JC, Thom SR, Yang M, Mijacika T, Dujic Z.

Sci Rep. 2017 Dec 5;7(1):16929. doi: 10.1038/s41598-017-17249-6.

25.

Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.

Al-Lamee R, Thompson D, Dehbi HM, Sen S, Tang K, Davies J, Keeble T, Mielewczik M, Kaprielian R, Malik IS, Nijjer SS, Petraco R, Cook C, Ahmad Y, Howard J, Baker C, Sharp A, Gerber R, Talwar S, Assomull R, Mayet J, Wensel R, Collier D, Shun-Shin M, Thom SA, Davies JE, Francis DP; ORBITA investigators.

Lancet. 2018 Jan 6;391(10115):31-40. doi: 10.1016/S0140-6736(17)32714-9. Epub 2017 Nov 2. Erratum in: Lancet. 2018 Jan 6;391(10115):30.

26.

Effect of Monthly, High-Dose, Long-Term Vitamin D Supplementation on Central Blood Pressure Parameters: A Randomized Controlled Trial Substudy.

Sluyter JD, Camargo CA Jr, Stewart AW, Waayer D, Lawes CMM, Toop L, Khaw KT, Thom SAM, Hametner B, Wassertheurer S, Parker KH, Hughes AD, Scragg R.

J Am Heart Assoc. 2017 Oct 24;6(10). pii: e006802. doi: 10.1161/JAHA.117.006802.

27.

Impact of switching to polypill based therapy by baseline potency of medication: Post-hoc analysis of the SPACE Collaboration dataset.

Webster R, Bullen C, Patel A, Selak V, Stepien S, Thom S, Rodgers A.

Int J Cardiol. 2017 Dec 15;249:443-447. doi: 10.1016/j.ijcard.2017.09.162. Epub 2017 Sep 20.

28.

Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors.

Sluyter JD, Hughes AD, Thom S, Lowe A, Camargo CA Jr, Hametner B, Wassertheurer S, Parker KH, Scragg RKR.

J Hum Hypertens. 2017 Nov;31(11):760. doi: 10.1038/jhh.2017.60. Epub 2017 Aug 31.

29.

Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability.

Thom SR, Bhopale VM, Yu K, Huang W, Kane MA, Margolis DJ.

J Biol Chem. 2017 Nov 3;292(44):18312-18324. doi: 10.1074/jbc.M117.802629. Epub 2017 Sep 25.

30.

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y2 receptor.

Kindon N, Davis A, Dougall I, Dixon J, Johnson T, Walters I, Thom S, McKechnie K, Meghani P, Stocks MJ.

Bioorg Med Chem Lett. 2017 Nov 1;27(21):4849-4853. doi: 10.1016/j.bmcl.2017.09.043. Epub 2017 Sep 21.

PMID:
28958619
31.

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Segura Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJL, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JMM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses, The CHD Exome+ Consortium, The ExomeBP Consortium, The T2D-GENES Consortium, The GoT2DGenes Consortium, The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium, The International Genomics of Blood Pressure (iGEN-BP) Consortium, Barnes MR, Tzoulaki I, Caulfield MJ, Elliott P; UK Biobank CardioMetabolic Consortium BP working group.

Nat Genet. 2017 Sep 27;49(10):1558. doi: 10.1038/ng1017-1558a. No abstract available.

32.

NOS1AP genetic variation is associated with impaired healing of diabetic foot ulcers and diminished response to healing of circulating stem/progenitor cells.

Margolis DJ, Hampton M, Hoffstad O, Mala DS, Mirza Z, Woltereck D, Shannon S, Troiano MA, Mitra N, Yang M, Bhopale VM, Thom SR.

Wound Repair Regen. 2017 Aug;25(4):733-736. doi: 10.1111/wrr.12564. Epub 2017 Aug 14.

33.

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB.

Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09438. doi: 10.1161/HYPERTENSIONAHA.117.09438. [Epub ahead of print]

34.

Oxidative stress mediated by nitrogen at elevated pressure inhibits non-small cell lung cancer growth.

Thom SR, Ma M, Bhopale VM, Zhou C, Mao L.

Exp Lung Res. 2017 May - Jun;43(4-5):175-180. doi: 10.1080/01902148.2017.1331478. Epub 2017 Jun 21.

PMID:
28636438
35.

Efficacy and Safety of Quarter-Dose Blood Pressure-Lowering Agents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Bennett A, Chow CK, Chou M, Dehbi HM, Webster R, Salam A, Patel A, Neal B, Peiris D, Thakkar J, Chalmers J, Nelson M, Reid C, Hillis GS, Woodward M, Hilmer S, Usherwood T, Thom S, Rodgers A.

Hypertension. 2017 Jul;70(1):85-93. doi: 10.1161/HYPERTENSIONAHA.117.09202. Epub 2017 Jun 5. Review.

36.

Inflammatory responses to acute elevations of carbon dioxide in mice.

Thom SR, Bhopale VM, Hu J, Yang M.

J Appl Physiol (1985). 2017 Aug 1;123(2):297-302. doi: 10.1152/japplphysiol.00343.2017. Epub 2017 May 11.

37.

Impact of switching from different treatment regimens to a fixed-dose combination pill (polypill) in patients with cardiovascular disease or similarly high risk.

Lafeber M, Spiering W, Visseren FL, Grobbee DE, Bots ML, Stanton A, Patel A, Prabhakaran D, Webster R, Thom S, Rodgers A; UMPIRE investigators.

Eur J Prev Cardiol. 2017 Jun;24(9):951-961. doi: 10.1177/2047487317695616. Epub 2017 Mar 8.

PMID:
28436727
38.

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundström J, Minelli C, Ruggiero D, Lyytikäinen LP, Tiller D, Smith JG, Monnereau C, Di Tullio MR, Musani SK, Morrison AC, Pers TH, Morley M, Kleber ME, Aragam J, Benjamin EJ, Bis JC, Bisping E, Broeckel U, Cheng S, Deckers JW, Del Greco M F, Edelmann F, Fornage M, Franke L, Friedrich N, Harris TB, Hofer E, Hofman A, Huang J, Hughes AD, Kähönen M, Investigators K, Kruppa J, Lackner KJ, Lannfelt L, Laskowski R, Launer LJ, Leosdottir M, Lin H, Lindgren CM, Loley C, MacRae CA, Mascalzoni D, Mayet J, Medenwald D, Morris AP, Müller C, Müller-Nurasyid M, Nappo S, Nilsson PM, Nuding S, Nutile T, Peters A, Pfeufer A, Pietzner D, Pramstaller PP, Raitakari OT, Rice KM, Rivadeneira F, Rotter JI, Ruohonen ST, Sacco RL, Samdarshi TE, Schmidt H, Sharp ASP, Shields DC, Sorice R, Sotoodehnia N, Stricker BH, Surendran P, Thom S, Töglhofer AM, Uitterlinden AG, Wachter R, Völzke H, Ziegler A, Münzel T, März W, Cappola TP, Hirschhorn JN, Mitchell GF, Smith NL, Fox ER, Dueker ND, Jaddoe VWV, Melander O, Russ M, Lehtimäki T, Ciullo M, Hicks AA, Lind L, Gudnason V, Pieske B, Barron AJ, Zweiker R, Schunkert H, Ingelsson E, Liu K, Arnett DK, Psaty BM, Blankenberg S, Larson MG, Felix SB, Franco OH, Zeller T, Vasan RS, Dörr M.

J Clin Invest. 2017 May 1;127(5):1798-1812. doi: 10.1172/JCI84840. Epub 2017 Apr 10.

39.

Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury.

Kumar A, Stoica BA, Loane DJ, Yang M, Abulwerdi G, Khan N, Kumar A, Thom SR, Faden AI.

J Neuroinflammation. 2017 Mar 15;14(1):47. doi: 10.1186/s12974-017-0819-4.

40.

Increased carbon dioxide levels stimulate neutrophils to produce microparticles and activate the nucleotide-binding domain-like receptor 3 inflammasome.

Thom SR, Bhopale VM, Hu J, Yang M.

Free Radic Biol Med. 2017 May;106:406-416. doi: 10.1016/j.freeradbiomed.2017.03.005. Epub 2017 Mar 10.

PMID:
28288918
41.

Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review.

Chow CK, Thakkar J, Bennett A, Hillis G, Burke M, Usherwood T, Vo K, Rogers K, Atkins E, Webster R, Chou M, Dehbi HM, Salam A, Patel A, Neal B, Peiris D, Krum H, Chalmers J, Nelson M, Reid CM, Woodward M, Hilmer S, Thom S, Rodgers A.

Lancet. 2017 Mar 11;389(10073):1035-1042. doi: 10.1016/S0140-6736(17)30260-X. Epub 2017 Feb 10.

42.

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJ, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JM, Tobin MD, Munroe PB, Ehret GB, Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses; BIOS Consortium; Lifelines Cohort Study; Understanding Society Scientific group; CHD Exome+ Consortium; ExomeBP Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; UK Biobank CardioMetabolic Consortium BP working group.

Nat Genet. 2017 Mar;49(3):403-415. doi: 10.1038/ng.3768. Epub 2017 Jan 30. Erratum in: Nat Genet. 2017 Sep 27;49(10 ):1558.

43.

Oscillatory shear stress, flow-mediated dilatation, and circulating microparticles at sea level and high altitude.

Tremblay JC, Thom SR, Yang M, Ainslie PN.

Atherosclerosis. 2017 Jan;256:115-122. doi: 10.1016/j.atherosclerosis.2016.12.004. Epub 2016 Dec 2.

PMID:
28010936
44.

Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors.

Sluyter JD, Hughes AD, Thom SA, Lowe A, Camargo CA Jr, Hametner B, Wassertheurer S, Parker KH, Scragg RK.

J Hum Hypertens. 2017 May;31(5):305-312. doi: 10.1038/jhh.2016.78. Epub 2016 Dec 22. Erratum in: J Hum Hypertens. 2017 Nov;31(11):760.

45.

Microparticle formation by platelets exposed to high gas pressures - An oxidative stress response.

Bhullar J, Bhopale VM, Yang M, Sethuraman K, Thom SR.

Free Radic Biol Med. 2016 Dec;101:154-162. doi: 10.1016/j.freeradbiomed.2016.10.010. Epub 2016 Oct 15.

PMID:
27751909
46.

Association of Retinopathy and Retinal Microvascular Abnormalities With Stroke and Cerebrovascular Disease.

Hughes AD, Falaschetti E, Witt N, Wijetunge S, Thom SA, Tillin T, Aldington SJ, Chaturvedi N.

Stroke. 2016 Nov;47(11):2862-2864. Epub 2016 Oct 11.

47.

Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies.

Sofat R, Cooper JA, Kumari M, Casas JP, Mitchell JP, Acharya J, Thom S, Hughes AD, Humphries SE, Hingorani AD.

PLoS Med. 2016 Oct 18;13(10):e1002146. doi: 10.1371/journal.pmed.1002146. eCollection 2016 Oct.

48.

True Resistant Hypertension Following Observed Drug Ingestion: A Systematic Evaluation.

Bunker J, Chang CL, Chapman N, Poulter N, Thom S, Thornton-Jones L, Sever P.

J Clin Hypertens (Greenwich). 2017 Mar;19(3):250-255. doi: 10.1111/jch.12896. Epub 2016 Aug 20.

49.

Do polypills lead to neglect of lifestyle risk factors? Findings from an individual participant data meta-analysis among 3140 patients at high risk of cardiovascular disease.

Selak V, Bullen C, Stepien S, Arroll B, Bots M, Bramley D, Cass A, Grobbee D, Hillis GS, Molanus B, Neal B, Patel A, Rafter N, Rodgers A, Thom S, Tonkin A, Usherwood T, Wadham A, Webster R.

Eur J Prev Cardiol. 2016 Sep;23(13):1393-400. doi: 10.1177/2047487316638216. Epub 2016 Mar 4. Review.

PMID:
26945024
50.

Dive, food, and exercise effects on blood microparticles in Steller sea lions (Eumetopias jubatus): exploring a biomarker for decompression sickness.

Fahlman A, Moore MJ, Trites AW, Rosen DA, Haulena M, Waller N, Neale T, Yang M, Thom SR.

Am J Physiol Regul Integr Comp Physiol. 2016 Apr 1;310(7):R596-601. doi: 10.1152/ajpregu.00512.2015. Epub 2016 Feb 3.

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