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Items: 45


Pilot trial of K562/GM-CSF whole-cell vaccination in MDS patients.

Robinson TM, Prince GT, Thoburn C, Warlick E, Ferguson A, Kasamon YL, Borrello IM, Hess A, Smith BD.

Leuk Lymphoma. 2018 Apr 4:1-11. doi: 10.1080/10428194.2018.1443449. [Epub ahead of print]


Detection and localization of surgically resectable cancers with a multi-analyte blood test.

Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz LA Jr, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N.

Science. 2018 Feb 23;359(6378):926-930. doi: 10.1126/science.aar3247. Epub 2018 Jan 18.


Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.

Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, Pardoll DM, Drake CG.

Cancer Immunol Res. 2017 Nov;5(11):992-1004. doi: 10.1158/2326-6066.CIR-17-0040. Epub 2017 Oct 2.


Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers.

Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA, Maitra A, Hanash SM, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10202-10207. doi: 10.1073/pnas.1704961114. Epub 2017 Sep 5.


Association of the autoimmune disease scleroderma with an immunologic response to cancer.

Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A.

Science. 2014 Jan 10;343(6167):152-7. doi: 10.1126/science.1246886. Epub 2013 Dec 5.


Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide.

Kanakry CG, Ganguly S, Zahurak M, Bolaños-Meade J, Thoburn C, Perkins B, Fuchs EJ, Jones RJ, Hess AD, Luznik L.

Sci Transl Med. 2013 Nov 13;5(211):211ra157. doi: 10.1126/scitranslmed.3006960.


Acute renal venous obstruction is more detrimental to the kidney than arterial occlusion: implication for murine models of acute kidney injury.

Li X, Liu M, Bedja D, Thoburn C, Gabrielson K, Racusen L, Rabb H.

Am J Physiol Renal Physiol. 2012 Mar 1;302(5):F519-25. doi: 10.1152/ajprenal.00011.2011. Epub 2011 Nov 23.


Allergic agonists in apheresis platelet products are associated with allergic transfusion reactions.

Savage WJ, Savage JH, Tobian AA, Thoburn C, Hamilton RG, Schroeder JT, Ness PM.

Transfusion. 2012 Mar;52(3):575-81. doi: 10.1111/j.1537-2995.2011.03310.x. Epub 2011 Aug 29.


Lenalidomide modulates IL-8 and anti-prostate antibody levels in men with biochemically recurrent prostate cancer.

Zabransky DJ, Smith HA, Thoburn CJ, Zahurak M, Keizman D, Carducci M, Eisenberger MA, McNeel DG, Drake CG, Antonarakis ES.

Prostate. 2012 Apr;72(5):487-98. doi: 10.1002/pros.21449. Epub 2011 Jul 11.


Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium.

Trimble CL, Clark RA, Thoburn C, Hanson NC, Tassello J, Frosina D, Kos F, Teague J, Jiang Y, Barat NC, Jungbluth AA.

J Immunol. 2010 Dec 1;185(11):7107-14. doi: 10.4049/jimmunol.1002756. Epub 2010 Oct 29.


Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.

Kanakry CG, Hess AD, Gocke CD, Thoburn C, Kos F, Meyer C, Briel J, Luznik L, Smith BD, Levitsky H, Karp JE.

Blood. 2011 Jan 13;117(2):608-17. doi: 10.1182/blood-2010-04-277939. Epub 2010 Oct 8.


Predictors of response to extracorporeal photopheresis in advanced mycosis fungoides and Sézary syndrome.

McGirt LY, Thoburn C, Hess A, Vonderheid EC.

Photodermatol Photoimmunol Photomed. 2010 Aug;26(4):182-91. doi: 10.1111/j.1600-0781.2010.00514.x.


Identification and characterization of a spontaneous ovarian carcinoma in Lewis rats.

Sharrow AC, Ronnett BM, Thoburn CJ, Barber JP, Giuntoli RL 2nd, Armstrong DK, Jones RJ, Hess AD.

J Ovarian Res. 2010 Mar 31;3:9. doi: 10.1186/1757-2215-3-9.


CD20, AIF-1, and TGF-beta in graft-versus-host disease: a study of mRNA expression in histologically matched skin biopsies.

Wu JM, Thoburn CJ, Wisell J, Farmer ER, Hess AD.

Mod Pathol. 2010 May;23(5):720-8. doi: 10.1038/modpathol.2010.48. Epub 2010 Feb 26.


Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3.

Trimble CL, Peng S, Thoburn C, Kos F, Wu TC.

Cancer Immunol Immunother. 2010 May;59(5):799-803. doi: 10.1007/s00262-009-0806-4. Epub 2009 Dec 13.


Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.

Savage WJ, Barber JP, Mukhina GL, Hu R, Chen G, Matsui W, Thoburn C, Hess AD, Cheng L, Jones RJ, Brodsky RA.

Exp Hematol. 2009 Jan;37(1):42-51. doi: 10.1016/j.exphem.2008.09.002. Epub 2008 Nov 14.


Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma.

Capriotti E, Vonderheid EC, Thoburn CJ, Wasik MA, Bahler DW, Hess AD.

Leuk Lymphoma. 2008 Jun;49(6):1190-201. doi: 10.1080/10428190802064917.


Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing.

Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, Meeker AK, Isaacs WB, Drake CG.

Clin Cancer Res. 2008 Jun 1;14(11):3254-61. doi: 10.1158/1078-0432.CCR-07-5164.


Chemokine receptor expression by leukemic T cells of cutaneous T-cell lymphoma: clinical and histopathological correlations.

Capriotti E, Vonderheid EC, Thoburn CJ, Bright EC, Hess AD.

J Invest Dermatol. 2007 Dec;127(12):2882-92. Epub 2007 Jun 28.


The effects of interleukin 10 and interferon gamma cytokine gene polymorphisms on survival after autologous bone marrow transplantation for patients with breast cancer.

Wu JM, Bensen-Kennedy D, Miura Y, Thoburn CJ, Armstrong D, Vogelsang GB, Hess AD.

Biol Blood Marrow Transplant. 2005 Jun;11(6):455-64.


Regulation of OX40 gene expression in graft-versus-host disease.

Miura Y, Thoburn CJ, Bright EC, Arai S, Hess AD.

Transplant Proc. 2005 Jan-Feb;37(1):57-61.


Antigen-specific T-lymphocyte responses in acute and chronic syngeneic graft-versus-host disease.

Hess AD, Thoburn CJ, Miura Y, Bright EC.

Transplant Proc. 2005 Jan-Feb;37(1):53-6.


Functionally divergent T lymphocyte responses induced by modification of a self-peptide from a tumor-associated antigen.

Hess AD, Thoburn CJ, Miura Y, Bright EC.

Clin Immunol. 2005 Mar;114(3):307-19.


Functional divergence of antigen-specific T-lymphocyte responses in syngeneic graft-versus-host disease.

Thoburn CJ, Miura Y, Bright EC, Hess AD.

Biol Blood Marrow Transplant. 2004 Sep;10(9):591-603.


Association of Foxp3 regulatory gene expression with graft-versus-host disease.

Miura Y, Thoburn CJ, Bright EC, Phelps ML, Shin T, Matsui EC, Matsui WH, Arai S, Fuchs EJ, Vogelsang GB, Jones RJ, Hess AD.

Blood. 2004 Oct 1;104(7):2187-93. Epub 2004 Jun 1.


Cytolytic effector mechanisms and gene expression in autologous graft-versus-host disease: distinct roles of perforin and Fas ligand.

Miura Y, Thoburn CJ, Bright EC, Hess AD.

Biol Blood Marrow Transplant. 2004 Mar;10(3):156-70.


Bronchial obstruction treated by fibreoptic-guided suction.

Klein AA, Thoburn C, Peters C, Hardee PS.

Eur J Anaesthesiol. 2002 Jan;19(1):76-7. No abstract available.


The N-terminal flanking region of the invariant chain peptide augments the immunogenicity of a cryptic "self" epitope from a tumor-associated antigen.

Hess AD, Thoburn C, Chen W, Miura Y, Van der Wall E.

Clin Immunol. 2001 Oct;101(1):67-76. Erratum in: Clin Immunol 2001 Dec;101(3):381.


Autoimmune-mediated vasculopathy.

Chen W, Thoburn CJ, Miura Y, Sommer M, Hruban R, Qian Z, Baldwin W, Hess AD.

Clin Immunol. 2001 Jul;100(1):57-70.


Autoreactive T-Cell subsets in acute and chronic syngeneic graft-versus-host disease.

Hess A, Thoburn C, Chen W, Horwitz L.

Transplant Proc. 2001 Feb-Mar;33(1-2):1754-6. No abstract available.


Complexity of effector mechanisms in cyclosporine-induced syngeneic graft-versus-host disease.

Hess AD, Thoburn CJ, Chen W, Horwitz LR.

Biol Blood Marrow Transplant. 2000;6(1):13-24.


Immune tolerance to self-MHC class II antigens after bone marrow transplantation.

Hess A, Horwitz L, Thoburn C.

Transplant Proc. 1999 Feb-Mar;31(1-2):688-9. No abstract available.


Pathogenic specificity of effector T lymphocytes in syngeneic graft-versus-host disease.

Thoburn C, Chen W, Horwitz L, Hess A.

Transplant Proc. 1999 Feb-Mar;31(1-2):684-6. No abstract available.


Specificity of effector mechanisms in syngeneic graft-vs-host disease: recognition of the MHC class II invariant chain peptide (CLIP).

Hess A, Thoburn C, Bright E, Horwitz L.

Transplant Proc. 1997 Feb-Mar;29(1-2):725-7. No abstract available.


Characterization of the V alpha/V beta autoreactive T-cell repertoire in syngeneic graft-vs-host disease.

Hess A, Ruvolo P, Fischer A, Horwitz L, Bright E, Thoburn C.

Transplant Proc. 1997 Feb-Mar;29(1-2):709-11. No abstract available.


Bryostatin can induce antigen-specific nonresponsiveness in human peripheral blood T cells.

Thoburn CJ, Hess AD.

Transplant Proc. 1995 Feb;27(1):443-4. No abstract available.


The combined use of elutriation and CD8/magnetic bead separation to engineer the bone marrow allograft.

Noga SJ, Davis JM, Vogelsang GB, Donnenberg AD, Thoburn C, Schepers K, Sproul J.

Prog Clin Biol Res. 1992;377:411-8. No abstract available.


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