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Items: 1 to 50 of 55

1.

Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα.

Shete V, Liu N, Jia Y, Viswakarma N, Reddy JK, Thimmapaya B.

Int J Mol Sci. 2018 Nov 22;19(12). pii: E3704. doi: 10.3390/ijms19123704.

2.

PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism.

Jia Y, Liu N, Viswakarma N, Sun R, Schipma MJ, Shang M, Thorp EB, Kanwar YS, Thimmapaya B, Reddy JK.

Int J Mol Sci. 2018 May 16;19(5). pii: E1485. doi: 10.3390/ijms19051485.

3.

Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

Jia Y, Chang HC, Schipma MJ, Liu J, Shete V, Liu N, Sato T, Thorp EB, Barger PM, Zhu YJ, Viswakarma N, Kanwar YS, Ardehali H, Thimmapaya B, Reddy JK.

PLoS One. 2016 Sep 30;11(9):e0164316. doi: 10.1371/journal.pone.0164316. eCollection 2016.

4.

Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

Jia Y, Chang HC, Schipma MJ, Liu J, Shete V, Liu N, Sato T, Thorp EB, Barger PM, Zhu YJ, Viswakarma N, Kanwar YS, Ardehali H, Thimmapaya B, Reddy JK.

PLoS One. 2016 Aug 22;11(8):e0160755. doi: 10.1371/journal.pone.0160755. eCollection 2016. Erratum in: PLoS One. 2016 Sep 30;11(9):e0164316.

5.

Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4.

Kain V, Kapadia B, Viswakarma N, Seshadri S, Prajapati B, Jena PK, Teja Meda CL, Subramanian M, Kaimal Suraj S, Kumar ST, Prakash Babu P, Thimmapaya B, Reddy JK, Parsa KV, Misra P.

Sci Rep. 2015 Oct 15;5:15197. doi: 10.1038/srep15197.

6.

PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.

Gao Q, Jia Y, Yang G, Zhang X, Boddu PC, Petersen B, Narsingam S, Zhu YJ, Thimmapaya B, Kanwar YS, Reddy JK.

Am J Pathol. 2015 May;185(5):1396-408. doi: 10.1016/j.ajpath.2015.01.018. Epub 2015 Mar 12.

7.

ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.

Kapadia B, Viswakarma N, Parsa KV, Kain V, Behera S, Suraj SK, Babu PP, Kar A, Panda S, Zhu YJ, Jia Y, Thimmapaya B, Reddy JK, Misra P.

PLoS One. 2013 Dec 17;8(12):e83787. doi: 10.1371/journal.pone.0083787. eCollection 2013.

8.

The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.

Viswakarma N, Jia Y, Bai L, Gao Q, Lin B, Zhang X, Misra P, Rana A, Jain S, Gonzalez FJ, Zhu YJ, Thimmapaya B, Reddy JK.

J Biol Chem. 2013 Sep 27;288(39):27898-911. doi: 10.1074/jbc.M113.486696. Epub 2013 Aug 13.

9.

Adenovirus E1A oncogene induces rereplication of cellular DNA and alters DNA replication dynamics.

Singhal G, Leo E, Setty SK, Pommier Y, Thimmapaya B.

J Virol. 2013 Aug;87(15):8767-78. doi: 10.1128/JVI.00879-13. Epub 2013 Jun 5.

10.

p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.

Ghosh AK, Bhattacharyya S, Lafyatis R, Farina G, Yu J, Thimmapaya B, Wei J, Varga J.

J Invest Dermatol. 2013 May;133(5):1302-10. doi: 10.1038/jid.2012.479. Epub 2013 Jan 10.

11.

c-Myc-induced aberrant DNA synthesis and activation of DNA damage response in p300 knockdown cells.

Sankar N, Kadeppagari RK, Thimmapaya B.

J Biol Chem. 2009 May 29;284(22):15193-205. doi: 10.1074/jbc.M900776200. Epub 2009 Mar 30.

12.

Adenovirus transforming protein E1A induces c-Myc in quiescent cells by a novel mechanism.

Kadeppagari RK, Sankar N, Thimmapaya B.

J Virol. 2009 May;83(10):4810-22. doi: 10.1128/JVI.02145-08. Epub 2009 Mar 11.

13.

Simian virus 40 large T overcomes p300 repression of c-Myc.

Singhal G, Kadeppagari RK, Sankar N, Thimmapaya B.

Virology. 2008 Aug 1;377(2):227-32. doi: 10.1016/j.virol.2008.04.042.

14.

p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-Myc.

Sankar N, Baluchamy S, Kadeppagari RK, Singhal G, Weitzman S, Thimmapaya B.

Oncogene. 2008 Sep 25;27(43):5717-28. doi: 10.1038/onc.2008.181. Epub 2008 Jun 9.

PMID:
18542060
15.

Relationship between E1A binding to cellular proteins, c-myc activation and S-phase induction.

Baluchamy S, Sankar N, Navaraj A, Moran E, Thimmapaya B.

Oncogene. 2007 Feb 1;26(5):781-7. Epub 2006 Jul 24.

PMID:
16862175
16.

The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest.

Nagl NG Jr, Zweitzig DR, Thimmapaya B, Beck GR Jr, Moran E.

Cancer Res. 2006 Feb 1;66(3):1289-93.

17.

Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis.

Liu H, Eksarko P, Temkin V, Haines GK 3rd, Perlman H, Koch AE, Thimmapaya B, Pope RM.

J Immunol. 2005 Dec 15;175(12):8337-45.

18.

Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism.

Fu M, Wang C, Rao M, Wu X, Bouras T, Zhang X, Li Z, Jiao X, Yang J, Li A, Perkins ND, Thimmapaya B, Kung AL, Munoz A, Giordano A, Lisanti MP, Pestell RG.

J Biol Chem. 2005 Aug 19;280(33):29728-42. Epub 2005 Jun 10.

19.

Effects of depletion of CREB-binding protein on c-Myc regulation and cell cycle G1-S transition.

Rajabi HN, Baluchamy S, Kolli S, Nag A, Srinivas R, Raychaudhuri P, Thimmapaya B.

J Biol Chem. 2005 Jan 7;280(1):361-74. Epub 2004 Nov 2.

20.

Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation.

Narayanan K, Srinivas R, Peterson MC, Ramachandran A, Hao J, Thimmapaya B, Scherer PE, George A.

J Biol Chem. 2004 Oct 22;279(43):44294-302. Epub 2004 Aug 11.

21.

Repression of c-Myc and inhibition of G1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity.

Baluchamy S, Rajabi HN, Thimmapaya R, Navaraj A, Thimmapaya B.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9524-9. Epub 2003 Jul 25.

22.

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

Misra P, Qi C, Yu S, Shah SH, Cao WQ, Rao MS, Thimmapaya B, Zhu Y, Reddy JK.

J Biol Chem. 2002 May 31;277(22):20011-9. Epub 2002 Mar 23.

23.

High-efficiency adenovirus-mediated in vivo gene transfer into neonatal and adult rodent skeletal muscle.

Sapru MK, McCormick KM, Thimmapaya B.

J Neurosci Methods. 2002 Feb 15;114(1):99-106.

PMID:
11850044
24.

Kruppel-like factor 4 regulates laminin alpha 3A expression in mammary epithelial cells.

Miller KA, Eklund EA, Peddinghaus ML, Cao Z, Fernandes N, Turk PW, Thimmapaya B, Weitzman SA.

J Biol Chem. 2001 Nov 16;276(46):42863-8. Epub 2001 Sep 10.

25.

Adenovirus-mediated targeted expression of toxic genes to adrenocorticotropin-producing pituitary tumors using the proopiomelanocortin promoter.

Lee EJ, Martinson F, Kotlar T, Thimmapaya B, Jameson JL.

J Clin Endocrinol Metab. 2001 Jul;86(7):3400-9.

PMID:
11443217
26.

Efficacy of adenoviral TNF alpha antisense is enhanced by a macrophage specific promoter.

Sidiropoulos P, Liu H, Mungre S, Anderson L, Thimmapaya B, Pope RM.

Gene Ther. 2001 Feb;8(3):223-31.

27.

Antisense-mediated depletion of p300 in human cells leads to premature G1 exit and up-regulation of c-MYC.

Kolli S, Buchmann AM, Williams J, Weitzman S, Thimmapaya B.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4646-51.

28.

Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun.

Georganas C, Liu H, Perlman H, Hoffmann A, Thimmapaya B, Pope RM.

J Immunol. 2000 Dec 15;165(12):7199-206.

29.

Regulation of TNF-alpha expression in normal macrophages: the role of C/EBPbeta.

Pope R, Mungre S, Liu H, Thimmapaya B.

Cytokine. 2000 Aug;12(8):1171-81.

PMID:
10930293
30.

Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach.

Anderson LM, Krotz S, Weitzman SA, Thimmapaya B.

Cancer Gene Ther. 2000 Jun;7(6):845-52.

31.

Stereotactic injection of adenoviral vectors that target gene expression to specific pituitary cell types: implications for gene therapy.

Lee EJ, Thimmapaya B, Jameson JL.

Neurosurgery. 2000 Jun;46(6):1461-8; discussion 1468-9.

PMID:
10834649
32.

Inhibition of laminin-5 production in breast epithelial cells by overexpression of p300.

Miller KA, Chung J, Lo D, Jones JC, Thimmapaya B, Weitzman SA.

J Biol Chem. 2000 Mar 17;275(11):8176-82.

33.

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.

Albanese C, D'Amico M, Reutens AT, Fu M, Watanabe G, Lee RJ, Kitsis RN, Henglein B, Avantaggiati M, Somasundaram K, Thimmapaya B, Pestell RG.

J Biol Chem. 1999 Nov 26;274(48):34186-95.

34.

Regulation of expression of N-methylpurine DNA glycosylase in human mammary epithelial cells: role of transcription factor AP-2.

Cerda SR, Chu SS, Garcia P, Chung J, Grumet JD, Thimmapaya B, Weitzman SA.

Chem Res Toxicol. 1999 Nov;12(11):1098-109.

PMID:
10563836
35.

Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer.

Anderson LM, Swaminathan S, Zackon I, Tajuddin AK, Thimmapaya B, Weitzman SA.

Gene Ther. 1999 May;6(5):854-64.

36.

Recombinant adenovirus is an appropriate vector for endocytotic protein trafficking studies in cultured neurons.

Yuan H, Zhai P, Anderson LM, Pan J, Thimmapaya B, Koo EH, Marquez-Sterling NR.

J Neurosci Methods. 1999 Apr 1;88(1):45-54.

PMID:
10379578
37.

p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter.

Jayaraman G, Srinivas R, Duggan C, Ferreira E, Swaminathan S, Somasundaram K, Williams J, Hauser C, Kurkinen M, Dhar R, Weitzman S, Buttice G, Thimmapaya B.

J Biol Chem. 1999 Jun 11;274(24):17342-52.

38.
39.

Regulation of cellular genes in a chromosomal context by the retinoblastoma tumor suppressor protein.

Buchmann AM, Swaminathan S, Thimmapaya B.

Mol Cell Biol. 1998 Aug;18(8):4565-76.

40.

Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.

Zagariya A, Mungre S, Lovis R, Birrer M, Ness S, Thimmapaya B, Pope R.

Mol Cell Biol. 1998 May;18(5):2815-24.

41.

A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.

Porrás A, Bennett J, Howe A, Tokos K, Bouck N, Henglein B, Sathyamangalam S, Thimmapaya B, Rundell K.

J Virol. 1996 Oct;70(10):6902-8.

42.

Transactivation of adenovirus E2-early promoter by E1A and E4 6/7 in the context of viral chromosome.

Swaminathan S, Thimmapaya B.

J Mol Biol. 1996 May 24;258(5):736-46.

PMID:
8637006
43.

Simian virus 40 large-T bypasses the translational block imposed by the phosphorylation of elF-2 alpha.

Swaminathan S, Rajan P, Savinova O, Jagus R, Thimmapaya B.

Virology. 1996 May 1;219(1):321-3.

44.

Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.

Somasundaram K, Jayaraman G, Williams T, Moran E, Frisch S, Thimmapaya B.

Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3088-93.

45.

Effect of single-base substitutions in the central domain of virus-associated RNA I on its function.

Rahman A, Malhotra P, Dhar R, Kewalramani T, Thimmapaya B.

J Virol. 1995 Jul;69(7):4299-307.

46.

Activation of interferon-inducible 2'-5' oligoadenylate synthetase by adenoviral VAI RNA.

Desai SY, Patel RC, Sen GC, Malhotra P, Ghadge GD, Thimmapaya B.

J Biol Chem. 1995 Feb 17;270(7):3454-61.

47.

A novel translational regulation function for the simian virus 40 large-T antigen gene.

Rajan P, Swaminathan S, Zhu J, Cole CN, Barber G, Tevethia MJ, Thimmapaya B.

J Virol. 1995 Feb;69(2):785-95.

48.

Regulation of adenovirus E2 transcription unit.

Swaminathan S, Thimmapaya B.

Curr Top Microbiol Immunol. 1995;199 ( Pt 3):177-94. Review. No abstract available.

PMID:
7555076
50.

E2F site activates transcription in fission yeast Schizosaccharomyces pombe and binds to a 30-kDa transcription factor.

Malhotra P, Manohar CF, Swaminathan S, Toyama R, Dhar R, Reichel R, Thimmapaya B.

J Biol Chem. 1993 Sep 25;268(27):20392-401.

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