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Items: 25

1.

Anti-tumor activity of a novel HS-mimetic-vascular endothelial growth factor binding small molecule.

Basappa, Sugahara K, Thimmaiah KN, Bid HK, Houghton PJ, Rangappa KS.

PLoS One. 2012;7(8):e39444. doi: 10.1371/journal.pone.0039444. Epub 2012 Aug 15. Erratum in: PLoS One. 2012;7(10):doi/10.1371/annotation/a685ce21-d7a1-4a5b-8fe8-734a071d53cd.

2.

Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling.

Thimmaiah KN, Easton JB, Houghton PJ.

Cancer Res. 2010 Mar 1;70(5):2000-9. doi: 10.1158/0008-5472.CAN-09-3693. Epub 2010 Feb 23.

3.

Anti-tubercular and anti-inflammatory activities of azetidin-2-one derivatives and their effects on the activity of Phospholipase A2.

Yerigeri MC, Murari SK, Thimmaiah KN, Math SK, Vishwanath BS.

Med Chem. 2008 Mar;4(2):190-3.

PMID:
18336338
4.

Plasmid loss in plasmid-carrying strains of Escherichia coli treated with phenoxazines and an approach to study their DNA binding properties.

Chandramouli KH, D'Souza CJ, Thimmaiah KN.

Nucleosides Nucleotides Nucleic Acids. 2008 Jan;27(1):70-83. doi: 10.1080/15257770701572030.

PMID:
18188772
5.

Acridones circumvent P-glycoprotein-associated multidrug resistance (MDR) in cancer cells.

Gopinath VS, Thimmaiah P, Thimmaiah KN.

Bioorg Med Chem. 2008 Jan 1;16(1):474-87. Epub 2007 Sep 15.

PMID:
17933543
6.

Targeting calmodulin in reversing multi drug resistance in cancer cells.

Mayur YC, Jagadeesh S, Thimmaiah KN.

Mini Rev Med Chem. 2006 Dec;6(12):1383-9. Review.

PMID:
17168814
7.

Sensitization of multidrug resistant (MDR) cancer cells to vinblastine by novel acridones: correlation between anti-calmodulin activity and anti-MDR activity.

Mayur YC, Padma T, Parimala BH, Chandramouli KH, Jagadeesh S, Gowda NM, Thimmaiah KN.

Med Chem. 2006 Jan;2(1):63-77.

PMID:
16787357
8.

Inhibition of calmodulin-dependent cyclic AMP phosphodiesterase by phenoxazines.

Jagadeesh S, Padma T, Parimala H, Chandramouli KH, D'Souza CJ, Thimmaiah KN.

Biochem Biophys Res Commun. 2006 Apr 14;342(3):690-701. Epub 2006 Feb 13.

PMID:
16494842
9.

Expression of hyaluronan in human tumor progression.

Boregowda RK, Appaiah HN, Siddaiah M, Kumarswamy SB, Sunila S, Thimmaiah KN, Mortha K, Toole B, Banerjee Sd.

J Carcinog. 2006 Jan 10;5:2.

10.

Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling.

Thimmaiah KN, Easton JB, Germain GS, Morton CL, Kamath S, Buolamwini JK, Houghton PJ.

J Biol Chem. 2005 Sep 9;280(36):31924-35. Epub 2005 Jul 11.

11.

Interaction of 2-chloro-N10-substituted phenoxazine with DNA and effect on DNA melting.

Chandramouli KH, Thimmaiah KN, Chandrashekar A, D'Souza CJ.

Nucleosides Nucleotides Nucleic Acids. 2004;23(10):1639-56.

PMID:
15620101
12.

Anti-calmodulin acridone derivatives modulate vinblastine resistance in multidrug resistant (MDR) cancer cells.

Hegde R, Thimmaiah P, Yerigeri MC, Krishnegowda G, Thimmaiah KN, Houghton PJ.

Eur J Med Chem. 2004 Feb;39(2):161-77.

PMID:
14987825
13.

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.

Cancer Res. 2003 Jan 15;63(2):364-74.

14.

Synthesis and chemical characterization of 2-methoxy-N(10)-substituted acridones needed to reverse vinblastine resistance in multidrug resistant (MDR) cancer cells.

Krishnegowda G, Thimmaiah P, Hegde R, Dass C, Houghton PJ, Thimmaiah KN.

Bioorg Med Chem. 2002 Jul;10(7):2367-80.

PMID:
11983534
15.

Interaction of substituted phenoxazine chemosensitizers with bovine serum albumin.

Channu BC, Kalpana HN, Eregowda GB, Dass C, Houghton PJ, Thimmaiah KN.

J Pharm Biomed Anal. 1999 Dec;21(4):775-85.

PMID:
10701943
16.

Characterization of 2-chloro-N10-substituted phenoxazines for reversing multidrug resistance in cancer cells.

Thimmaiah KN, Jayashree BS, Germain GS, Houghton PJ, Horton JK.

Oncol Res. 1998;10(1):29-41.

PMID:
9613455
17.

Characterization of a novel bisacridone and comparison with PSC 833 as a potent and poorly reversible modulator of P-glycoprotein.

Horton JK, Thimmaiah KN, Altenberg GA, Castro AF, Germain GS, Gowda GK, Houghton PJ.

Mol Pharmacol. 1997 Dec;52(6):948-57.

PMID:
9415704
18.

Liquid secondary ionization mass spectrometry and collision-induced dissociation study of 2-chloro-N10-substituted phenoxazines.

Dass C, Thimmaiah KN, Jayashree BS, Houghton PJ.

J Mass Spectrom. 1997 Dec;32(12):1279-89.

PMID:
9423281
19.

Analysis of phenoxazine chemosensitizers: an electron ionization and keV-ion beam bombardment mass spectrometry study.

Dass C, Thimmaiah KN, Jayashree BS, Seshadri R, Israel M, Houghton PJ.

Biol Mass Spectrom. 1994 Mar;23(3):140-6.

PMID:
8148404
20.

Pharmacological characterization of N-substituted phenoxazines directed toward reversing Vinca alkaloid resistance in multidrug-resistant cancer cells.

Horton JK, Thimmaiah KN, Harwood FC, Kuttesch JF, Houghton PJ.

Mol Pharmacol. 1993 Sep;44(3):552-9.

PMID:
8103911
21.

Synthesis and chemical characterization of N-substituted phenoxazines directed toward reversing vinca alkaloid resistance in multidrug-resistant cancer cells.

Thimmaiah KN, Horton JK, Seshadri R, Israel M, Houghton JA, Harwood FC, Houghton PJ.

J Med Chem. 1992 Sep 4;35(18):3358-64.

PMID:
1527786
22.
23.

Modulation by verapamil of vincristine pharmacokinetics and toxicity in mice bearing human tumor xenografts.

Horton JK, Thimmaiah KN, Houghton JA, Horowitz ME, Houghton PJ.

Biochem Pharmacol. 1989 Jun 1;38(11):1727-36.

PMID:
2735930
24.

Structural studies on the degradation products of vincristine dihydrogen sulfate.

Sethi VS, Thimmaiah KN.

Cancer Res. 1985 Nov;45(11 Pt 1):5386-9.

25.

Chemical characterization of the degradation products of vinblastine dihydrogen sulfate.

Thimmaiah KN, Sethi VS.

Cancer Res. 1985 Nov;45(11 Pt 1):5382-5.

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