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Items: 1 to 50 of 63

1.

Transport of iron chelators and chelates across MDCK cell monolayers: implications for iron excretion during chelation therapy.

Huang XP, Thiessen JJ, Spino M, Templeton DM.

Int J Hematol. 2010 Apr;91(3):401-12. doi: 10.1007/s12185-010-0510-3. Epub 2010 Mar 9.

PMID:
20213118
2.

Operating characteristics of a partial-block randomized crossover bioequivalence study for dutasteride, a drug with a long half-life: investigation through simulation and comparison with final results.

Cai G, Thiessen JJ, Baidoo CA, Fossler MJ.

J Clin Pharmacol. 2010 Oct;50(10):1142-50. doi: 10.1177/0091270009355155. Epub 2010 Feb 16.

PMID:
20160156
3.

Pharmacokinetic disposition of the oral iron chelator deferiprone in the domestic pigeon (Columba livia).

Whiteside DP, Barker IK, Conlon PD, Tesoro A, Thiessen JJ, Mehren KG, Jacobs RM, Spino M.

J Avian Med Surg. 2007 Jun;21(2):121-9.

PMID:
18065133
4.

Pharmacokinetic disposition of the oral iron chelator deferiprone in the white leghorn chicken.

Whiteside DP, Barker IK, Conlon PD, Tesoro A, Thiessen JJ, Mehren KG, Jacobs RM, Spino M.

J Avian Med Surg. 2007 Jun;21(2):110-20.

PMID:
18065132
5.

PSC 833, an inhibitor of P-glycoprotein inhibits 1,2-dimethylhydrazine-induced colorectal carcinogenesis in male Fischer F344 rats.

Kankesan J, Laconi E, Medline A, Thiessen JJ, Ling V, Rao PM, Rajalakshmi S, Sarma DS.

Anticancer Res. 2006 Mar-Apr;26(2A):995-9.

6.

Transport kinetics of iron chelators and their chelates in Caco-2 cells.

Huang XP, Spino M, Thiessen JJ.

Pharm Res. 2006 Feb;23(2):280-90. Epub 2006 Jan 1.

PMID:
16388408
7.

Validated HPLC assay for iron determination in biological matrices based on ferrioxamine formation.

Tesoro A, Novakovic J, Thiessen JJ, Spino M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 5;823(2):177-83.

PMID:
16023418
8.

Pharmacokinetic studies of a novel 1,2,4-thiadiazole derivative, inhibitor of Factor XIIIa, in the rabbit by a validated HPLC method.

Novakovic J, Wodzinska J, Tesoro A, Thiessen JJ, Spino M.

J Pharm Biomed Anal. 2005 Jun 15;38(2):293-7. Epub 2005 Feb 12.

PMID:
15925221
9.

Metabolic and pharmacokinetic evaluation of a novel 3-hydroxypyridinone iron chelator, CP502, in the rat.

Novakovic J, Tesoro A, Thiessen JJ, Spino M.

Eur J Drug Metab Pharmacokinet. 2004 Oct-Dec;29(4):221-4.

PMID:
15726881
10.

A comparative clarithromycin bioavailability study: determination of clarithromycin and 14-(R)-hydroxyclarithromycin under fasting and fed conditions.

Benninger P, Cooper A, Moisan R, Patel P, Elvin A, Thiessen JJ.

Int J Clin Pharmacol Ther. 2004 Jun;42(6):342-9.

PMID:
15222728
11.

L-arginine transport in the human coronary and peripheral circulation.

Miner SE, Al-Hesayen A, Kelly S, Benson T, Thiessen JJ, Young VR, Parker JD.

Circulation. 2004 Mar 16;109(10):1278-83. Epub 2004 Mar 8.

PMID:
15007014
12.

Increased endothelin-1 production in patients with chronic heart failure.

Parker JD, Thiessen JJ.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1141-5.

13.

Phase I and pharmacokinetic study of fostriecin given as an intravenous bolus daily for five consecutive days.

LĂȘ LH, Erlichman C, Pillon L, Thiessen JJ, Day A, Wainman N, Eisenhauer EA, Moore MJ.

Invest New Drugs. 2004 Apr;22(2):159-67.

PMID:
14739664
14.

Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.

Kankesan J, Vanama R, Yusuf A, Thiessen JJ, Ling V, Rao PM, Rajalakshmi S, Sarma DS.

Carcinogenesis. 2004 Mar;25(3):425-30. Epub 2003 Nov 21.

PMID:
14633655
15.
16.

Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats.

Kankesan J, Yusuf A, Laconi E, Vanama R, Bradley G, Thiessen JJ, Ling V, Rao PM, Rajalakshmi S, Sarma DS.

Carcinogenesis. 2003 Dec;24(12):1977-84. Epub 2003 Sep 11.

PMID:
12970066
17.

Effect of PSC 833, a potent inhibitor of P-glycoprotein, on the growth of astrocytoma cells in vitro.

Sadanand V, Kankesan J, Yusuf A, Stewart C, Rutka JT, Thiessen JJ, Ling V, Rao PM, Rajalakshmi S, Sarma DS.

Cancer Lett. 2003 Jul 30;198(1):21-7.

PMID:
12893426
18.
19.

Human endothelin-1 clearance kinetics revealed by a radiotracer technique.

Parker JD, Thiessen JJ, Reilly R, Tong JH, Stewart DJ, Pandey AS.

J Pharmacol Exp Ther. 1999 Apr;289(1):261-5.

PMID:
10087013
20.

Phase I and pharmacologic study of 9-aminocamptothecin colloidal dispersion formulation given as a 24-hour continuous infusion weekly times four every 5 weeks.

Siu LL, Oza AM, Eisenhauer EA, Firby PS, Thiessen JJ, Michael M, Wainman N, Manzo J, Feld R, Goldberg RA, Moore MJ.

J Clin Oncol. 1998 Mar;16(3):1122-30.

PMID:
9508199
21.

Does thiopentone delay recovery in children premedicated with midazolam?

Morley-Forster P, McAllister JD, Vandenberghe H, Thiessen JJ, White A, Taylor M, Knoppert DC.

Paediatr Anaesth. 1997;7(4):279-85.

PMID:
9243684
22.

Pharmacokinetic and pharmacodynamic studies of 9-aminocamptothecin in vitro against human cancer cells.

Li M, Moore MJ, Berry B, Thiessen JJ.

Ann N Y Acad Sci. 1996 Dec 13;803:315-7. No abstract available.

PMID:
8993527
23.

Chemotherapy with focal therapy can cure intraocular retinoblastoma without radiotherapy.

Gallie BL, Budning A, DeBoer G, Thiessen JJ, Koren G, Verjee Z, Ling V, Chan HS.

Arch Ophthalmol. 1996 Nov;114(11):1321-8. Erratum in: Arch Ophthalmol 1997 Apr;115(4):525.

PMID:
8906022
24.

Combining cyclosporin with chemotherapy controls intraocular retinoblastoma without requiring radiation.

Chan HS, DeBoer G, Thiessen JJ, Budning A, Kingston JE, O'Brien JM, Koren G, Giesbrecht E, Haddad G, Verjee Z, Hungerford JL, Ling V, Gallie BL.

Clin Cancer Res. 1996 Sep;2(9):1499-508.

25.

Tiaprofenic acid: an uncommon cause of cystitis often misdiagnosed as interstitial cystitis.

Heritz DM, Thiessen JJ.

Can J Urol. 1996 Mar;3(1):202-205.

PMID:
12741979
26.

The effects of age and chemotherapy on gentamicin pharmacokinetics and dosing in pediatric oncology patients.

Ho KK, Bryson SM, Thiessen JJ, Greenberg ML, Einarson TR, Leson CL.

Pharmacotherapy. 1995 Nov-Dec;15(6):754-64.

PMID:
8602384
27.

A clinical and pharmacological study of 5-fluorouracil, leucovorin and interferon alfa in advanced colorectal cancer.

Moore MJ, Kaizer L, Erlichman C, Myers R, Feld R, Thiessen JJ, Fine S.

Cancer Chemother Pharmacol. 1995;37(1-2):86-90.

PMID:
7497602
28.
29.

Determination of fostriecin pharmacokinetics in plasma using high-pressure liquid chromatography assay.

Pillon L, Moore MJ, Thiessen JJ.

Ther Drug Monit. 1994 Apr;16(2):186-90.

PMID:
8009568
30.

Variability in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in women receiving adjuvant treatment for breast cancer.

Moore MJ, Erlichman C, Thiessen JJ, Bunting PS, Hardy R, Kerr I, Soldin S.

Cancer Chemother Pharmacol. 1994;33(6):472-6.

PMID:
8137456
31.

Phase I pharmacokinetic study of cyclosporin A combined with doxorubicin.

Erlichman C, Moore M, Thiessen JJ, Kerr IG, Walker S, Goodman P, Bjarnason G, DeAngelis C, Bunting P.

Cancer Res. 1993 Oct 15;53(20):4837-42.

32.

Development and validation of a limited sampling strategy for 5-fluorouracil given by bolus intravenous administration.

Moore MJ, Bunting P, Yuan S, Thiessen JJ.

Ther Drug Monit. 1993 Oct;15(5):394-9.

PMID:
8249045
33.

Compartmental analysis of the pharmacokinetics of radioiodinated monoclonal antibody B72.3 in colon cancer patients.

Reilly RM, Kirsh J, Gallinger S, Thiessen JJ, Damani M, Hay K, Polihronis J, Schmocker B, Odze R, Houle S, et al.

Nucl Med Biol. 1993 Jan;20(1):57-64.

PMID:
8461880
34.
35.

Competitive binding of sulfamethazine and its N-acetylated metabolite.

Tsang YC, Thiessen JJ.

Biopharm Drug Dispos. 1989 Sep-Oct;10(5):465-79.

PMID:
2804251
36.

Rapid development of enhanced clearance after high-dose cyclophosphamide.

Moore MJ, Hardy RW, Thiessen JJ, Soldin SJ, Erlichman C.

Clin Pharmacol Ther. 1988 Dec;44(6):622-8.

PMID:
3058371
37.

Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease.

Knoppert DC, Spino M, Beck R, Thiessen JJ, MacLeod SM.

Clin Pharmacol Ther. 1988 Sep;44(3):254-64.

PMID:
3046811
38.

Disposition of cyclophosphamide on two consecutive cycles of treatment in patients with ovarian carcinoma.

Erlichman C, Soldin SJ, Hardy RW, Thiessen JJ, Sturgeon JF, Fine S, Baskerville T.

Arzneimittelforschung. 1988 Jun;38(6):839-42.

PMID:
3178926
39.

Determinants of low serum concentrations of salicylates in patients with Kawasaki disease.

Koren G, Schaffer F, Silverman E, Walker S, Duffy C, Stein L, Suria D, Schue S, Thiessen JJ, Gelfand E, et al.

J Pediatr. 1988 Apr;112(4):663-7.

PMID:
3351695
40.

Ethanol vapours above lacrimal fluid in the rabbit.

Giles HG, Sandrin S, Kapur BM, Thiessen JJ.

Can J Physiol Pharmacol. 1987 Dec;65(12):2491-3.

PMID:
3449205
41.

Ethanol vapor above skin: determination by a gas sensor instrument and relationship with plasma concentration.

Giles HG, Meggiorini S, Renaud GE, Thiessen JJ, Vidins EI, Compton KV, Saldivia V, Orrego H, Israel Y.

Alcohol Clin Exp Res. 1987 Jun;11(3):249-53.

PMID:
3307488
42.

Disposition of total and free cisplatin on two consecutive treatment cycles in patients with ovarian cancer.

Erlichman C, Soldin SJ, Thiessen JJ, Sturgeon JF, Fine S.

Cancer Chemother Pharmacol. 1987;19(1):75-9.

PMID:
3815729
43.

Daily maintenance dose of a long-acting theophylline from a single theophylline serum level.

Goldstein RS, Allen LC, Thiessen JJ, Michalko K, Dayneka N, Woolf CR.

Chest. 1986 Jan;89(1):103-8.

PMID:
3940768
44.

Assessment of glomerular filtration rate and effective renal plasma flow in cystic fibrosis.

Spino M, Chai RP, Isles AF, Balfe JW, Brown RG, Thiessen JJ, MacLeod SM.

J Pediatr. 1985 Jul;107(1):64-70.

PMID:
3891948
45.

Valproic acid disposition in rabbits during chronic treatment with Escherichia coli endotoxin.

Thiessen JJ, Albright PS, Bruni J, Suria D.

Can J Physiol Pharmacol. 1985 Apr;63(4):315-9.

PMID:
3924379
46.
47.

Cloxacillin absorption and disposition in cystic fibrosis.

Spino M, Chai RP, Isles AF, Thiessen JJ, Tesoro A, Gold R, MacLeod SM.

J Pediatr. 1984 Nov;105(5):829-35.

PMID:
6502318
48.

Indocyanine green pharmacokinetics in the rabbit.

Thiessen JJ, Rappaport PL, Eppel JG.

Can J Physiol Pharmacol. 1984 Sep;62(9):1078-85.

PMID:
6498620
49.

High-performance liquid chromatographic analysis of amiloride in plasma and urine.

Yip MS, Coates PE, Thiessen JJ.

J Chromatogr. 1984 May 11;307(2):343-50.

PMID:
6736181
50.

Placental drug transfer in near-term ewes: acetylsalicylic and salicylic acid.

Thiessen JJ, Salama RB, Coceani F, Olley PM.

Can J Physiol Pharmacol. 1984 Apr;62(4):441-5.

PMID:
6733590

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