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FACT mediates cohesin function on chromatin.

Garcia-Luis J, Lazar-Stefanita L, Gutierrez-Escribano P, Thierry A, Cournac A, García A, González S, Sánchez M, Jarmuz A, Montoya A, Dore M, Kramer H, Karimi MM, Antequera F, Koszul R, Aragon L.

Nat Struct Mol Biol. 2019 Oct;26(10):970-979. doi: 10.1038/s41594-019-0307-x. Epub 2019 Oct 3.


Use of Highly Individualized Complement Blockade Has Revolutionized Clinical Outcomes after Kidney Transplantation and Renal Epidemiology of Atypical Hemolytic Uremic Syndrome.

Zuber J, Frimat M, Caillard S, Kamar N, Gatault P, Petitprez F, Couzi L, Jourde-Chiche N, Chatelet V, Gaisne R, Bertrand D, Bamoulid J, Louis M, Sberro Soussan R, Navarro D, Westeel PF, Frimat L, Colosio C, Thierry A, Rivalan J, Albano L, Arzouk N, Cornec-Le Gall E, Claisse G, Elias M, El Karoui K, Chauvet S, Coindre JP, Rerolle JP, Tricot L, Sayegh J, Garrouste C, Charasse C, Delmas Y, Massy Z, Hourmant M, Servais A, Loirat C, Fakhouri F, Pouteil-Noble C, Peraldi MN, Legendre C, Rondeau E, Le Quintrec M, Frémeaux-Bacchi V.

J Am Soc Nephrol. 2019 Oct 1. pii: ASN.2019040331. doi: 10.1681/ASN.2019040331. [Epub ahead of print]


Education as the Great Equalizer? Racial and Ethnic Differences in the Effect of Education on Cognitive Impairment in Later Life.

Sherman-Wilkins KJ, Thierry AD.

Geriatrics (Basel). 2019 Sep 5;4(3). pii: E51. doi: 10.3390/geriatrics4030051.


MetaTOR: A Computational Pipeline to Recover High-Quality Metagenomic Bins From Mammalian Gut Proximity-Ligation (meta3C) Libraries.

Baudry L, Foutel-Rodier T, Thierry A, Koszul R, Marbouty M.

Front Genet. 2019 Aug 20;10:753. doi: 10.3389/fgene.2019.00753. eCollection 2019.


Adherence profiles in kidney transplant patients: Causes and consequences.

Villeneuve C, Rousseau A, Rerolle JP, Couzi L, Kamar N, Essig M, Etienne I, Westeel PF, Büchler M, Esposito L, Thierry A, Marquet P, Monchaud C.

Patient Educ Couns. 2019 Aug 7. pii: S0738-3991(19)30318-0. doi: 10.1016/j.pec.2019.08.002. [Epub ahead of print]


A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients.

Bassani-Sternberg M, Digklia A, Huber F, Wagner D, Sempoux C, Stevenson BJ, Thierry AC, Michaux J, Pak H, Racle J, Boudousquie C, Balint K, Coukos G, Gfeller D, Martin Lluesma S, Harari A, Demartines N, Kandalaft LE.

Front Immunol. 2019 Aug 8;10:1832. doi: 10.3389/fimmu.2019.01832. eCollection 2019.


Identification and quantification of natural compounds produced by antifungal bioprotective cultures in dairy products.

Leyva Salas M, Mounier J, Maillard MB, Valence F, Coton E, Thierry A.

Food Chem. 2019 Dec 15;301:125260. doi: 10.1016/j.foodchem.2019.125260. Epub 2019 Jul 25.


[Incidence of epilepsy after cerebrovascular accident in Parakou in 2014].

Thierry A, Donald A, Mendinatou A, Dismand H.

Pan Afr Med J. 2019 Feb 7;32:69. doi: 10.11604/pamj.2019.32.69.16897. eCollection 2019. French.


PRODIG (Prevention of new onset diabetes after transplantation by a short term treatment of Vildagliptin in the early renal post-transplant period) study: study protocol for a randomized controlled study.

Gaiffe E, Crepin T, Bamoulid J, Courivaud C, Büchler M, Cassuto E, Albano L, Chemouny JM, Choukroun G, Hazzan M, Kessler L, Legendre C, Le Meur Y, Ouali N, Thierry A, Anota A, Nerich V, Limat S, Bonnetain F, Vernerey D, Ducloux D.

Trials. 2019 Jun 21;20(1):375. doi: 10.1186/s13063-019-3392-6.


Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis.

Guérin TM, Béneut C, Barinova N, López V, Lazar-Stefanita L, Deshayes A, Thierry A, Koszul R, Dubrana K, Marcand S.

Mol Cell. 2019 Jul 11;75(1):131-144.e3. doi: 10.1016/j.molcel.2019.05.021. Epub 2019 Jun 13.


Clinicopathological spectrum of renal parenchymal involvement in B-cell lymphoproliferative disorders.

Javaugue V, Debiais-Delpech C, Nouvier M, Gand E, Chauvet S, Ecotiere L, Desport E, Goujon JM, Delwail V, Guidez S, Tomowiak C, Leleu X, Jaccard A, Rioux-Leclerc N, Vigneau C, Fermand JP, Touchard G, Thierry A, Bridoux F.

Kidney Int. 2019 Jul;96(1):94-103. doi: 10.1016/j.kint.2019.01.027. Epub 2019 Mar 15.


Epitope load identifies kidney transplant recipients at risk of allosensitization following minimization of immunosuppression.

Snanoudj R, Kamar N, Cassuto E, Caillard S, Metzger M, Merville P, Thierry A, Jollet I, Grimbert P, Anglicheau D, Hazzan M, Choukroun G, Hurault De Ligny B, Janbon B, Vuiblet V, Devys A, Le Meur Y, Delahousse M, Morelon E, Bailly E, Girerd S, Amokrane K, Legendre C, Hertig A, Rondeau E, Taupin JL.

Kidney Int. 2019 Jun;95(6):1471-1485. doi: 10.1016/j.kint.2018.12.029. Epub 2019 Mar 5.


Quantifying circulating cell-free DNA in humans.

Meddeb R, Dache ZAA, Thezenas S, Otandault A, Tanos R, Pastor B, Sanchez C, Azzi J, Tousch G, Azan S, Mollevi C, Adenis A, El Messaoudi S, Blache P, Thierry AR.

Sci Rep. 2019 Mar 26;9(1):5220. doi: 10.1038/s41598-019-41593-4.


Development of antifungal ingredients for dairy products: From in vitro screening to pilot scale application.

Garnier L, Mounier J, Lê S, Pawtowski A, Pinon N, Camier B, Chatel M, Garric G, Thierry A, Coton E, Valence F.

Food Microbiol. 2019 Aug;81:97-107. doi: 10.1016/ Epub 2018 Nov 14.


Evaluation of outcomes in renal transplantation with hypothermic machine perfusion for the preservation of kidneys from expanded criteria donors.

Savoye E, Macher MA, Videcoq M, Gatault P, Hazzan M, Abboud I, Thierry A, Bertrand D, Drouin S, Sayegh J, Barrou B, Badet L, Bastien O, Huot O, Lamotte C, Logerot H, Legeai C, Antoine C.

Clin Transplant. 2019 May;33(5):e13536. doi: 10.1111/ctr.13536. Epub 2019 Apr 10.


Guidelines for the Preanalytical Conditions for Analyzing Circulating Cell-Free DNA.

Meddeb R, Pisareva E, Thierry AR.

Clin Chem. 2019 May;65(5):623-633. doi: 10.1373/clinchem.2018.298323. Epub 2019 Feb 21.


Recent advances in circulating nucleic acids in oncology.

Otandault A, Anker P, Al Amir Dache Z, Guillaumon V, Meddeb R, Pastor B, Pisareva E, Sanchez C, Tanos R, Tousch G, Schwarzenbach H, Thierry AR.

Ann Oncol. 2019 Mar 1;30(3):374-384. doi: 10.1093/annonc/mdz031.


Hypercholesterolemia-induced increase in plasma oxidized LDL abrogated pro angiogenic response in kidney grafts.

Kerforne T, Favreau F, Khalifeh T, Maiga S, Allain G, Thierry A, Dierick M, Baulier E, Steichen C, Hauet T.

J Transl Med. 2019 Jan 14;17(1):26. doi: 10.1186/s12967-018-1764-4.


Generation of a Metagenomics Proximity Ligation 3C Library of a Mammalian Gut Microbiota.

Foutel-Rodier T, Thierry A, Koszul R, Marbouty M.

Methods Enzymol. 2018;612:183-195. doi: 10.1016/bs.mie.2018.08.001. Epub 2018 Sep 18.


New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis.

Sanchez C, Snyder MW, Tanos R, Shendure J, Thierry AR.

NPJ Genom Med. 2018 Nov 23;3:31. doi: 10.1038/s41525-018-0069-0. eCollection 2018.


[Liquid biopsy: a possible approach for cancer screening].

Thierry AR, Tanos R.

Med Sci (Paris). 2018 Oct;34(10):824-832. doi: 10.1051/medsci/2018208. Epub 2018 Nov 19. Review. French.


The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33.

Ferhat MH, Robin A, Barbier L, Thierry A, Gombert JM, Barbarin A, Herbelin A.

Front Immunol. 2018 Oct 15;9:2308. doi: 10.3389/fimmu.2018.02308. eCollection 2018. Review.


Nuclear introns help unravel the diversification history of the Australo-Pacific Petroica robins.

Kearns AM, Malloy JF, Gobbert MK, Thierry A, Joseph L, Driskell AC, Omland KE.

Mol Phylogenet Evol. 2019 Feb;131:48-54. doi: 10.1016/j.ympev.2018.10.024. Epub 2018 Oct 25.


A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway.

Grimaldi M, Boulahtouf A, Prévostel C, Thierry A, Balaguer P, Blache P.

Front Pharmacol. 2018 Oct 11;9:1160. doi: 10.3389/fphar.2018.01160. eCollection 2018.


Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin.

Moreau P, Cournac A, Palumbo GA, Marbouty M, Mortaza S, Thierry A, Cairo S, Lavigne M, Koszul R, Neuveut C.

Nat Commun. 2018 Oct 15;9(1):4268. doi: 10.1038/s41467-018-06739-4.


50-Gy Stereotactic Body Radiation Therapy to the Dominant Intraprostatic Nodule: Results From a Phase 1a/b Trial.

Herrera FG, Valerio M, Berthold D, Tawadros T, Meuwly JY, Vallet V, Baumgartner P, Thierry AC, De Bari B, Jichlinski P, Kandalaft L, Coukos G, Harari A, Bourhis J.

Int J Radiat Oncol Biol Phys. 2019 Feb 1;103(2):320-334. doi: 10.1016/j.ijrobp.2018.09.023. Epub 2018 Sep 27.


Antifungal Activity of Lactic Acid Bacteria Combinations in Dairy Mimicking Models and Their Potential as Bioprotective Cultures in Pilot Scale Applications.

Leyva Salas M, Thierry A, Lemaître M, Garric G, Harel-Oger M, Chatel M, Lê S, Mounier J, Valence F, Coton E.

Front Microbiol. 2018 Aug 7;9:1787. doi: 10.3389/fmicb.2018.01787. eCollection 2018.


Characterizing meiotic chromosomes' structure and pairing using a designer sequence optimized for Hi-C.

Muller H, Scolari VF, Agier N, Piazza A, Thierry A, Mercy G, Descorps-Declere S, Lazar-Stefanita L, Espeli O, Llorente B, Fischer G, Mozziconacci J, Koszul R.

Mol Syst Biol. 2018 Jul 16;14(7):e8293. doi: 10.15252/msb.20188293.


No impact of disseminated intravascular coagulation in kidney donors on long-term kidney transplantation outcome: A multicenter propensity-matched study.

Garrouste C, Baudenon J, Gatault P, Pereira B, Etienne I, Thierry A, Szlavik N, Aniort J, Rabant M, Lambert C, Sayegh J, Oniszczuk J, Anglicheau D, Heng AE.

Am J Transplant. 2019 Feb;19(2):448-456. doi: 10.1111/ajt.15008. Epub 2018 Aug 23.


The Candidate Blood-stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase 1 Trial in Exposed and Nonexposed Volunteers.

Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo RW, Theisen M, Thierry AC, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo SA.

Clin Infect Dis. 2019 Jan 18;68(3):466-474. doi: 10.1093/cid/ciy514.


Cytotoxicity assessment, inflammatory properties, and cellular uptake of Neutraplex lipid-based nanoparticles in THP-1 monocyte-derived macrophages.

Berger E, Breznan D, Stals S, Jasinghe VJ, Gonçalves D, Girard D, Faucher S, Vincent R, Thierry AR, Lavigne C.

Nanobiomedicine (Rij). 2017 Dec 21;4:1849543517746259. doi: 10.1177/1849543517746259. eCollection 2017 Jan-Dec.


A Step Closer to Cancer Screening by Blood Test.

Thierry AR.

Clin Chem. 2018 Oct;64(10):1420-1422. doi: 10.1373/clinchem.2018.287847. Epub 2018 Jun 14. No abstract available.


Mesencephalic dopamine neurons interfacing the shell of nucleus accumbens and the dorsolateral striatum in the rat.

Wouterlood FG, Engel A, Daal M, Houwen G, Meinderts A, Jordà Siquier T, Beliën JAM, van Dongen YC, Scheel-Krüger J, Thierry AM, Groenewegen HJ, Deniau JM.

J Neurosci Res. 2018 Sep;96(9):1518-1542. doi: 10.1002/jnr.24242. Epub 2018 Apr 25.


Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer.

Jeitany M, Leroy C, Tosti P, Lafitte M, Le Guet J, Simon V, Bonenfant D, Robert B, Grillet F, Mollevi C, El Messaoudi S, Otandault A, Canterel-Thouennon L, Busson M, Thierry AR, Martineau P, Pannequin J, Roche S, Sirvent A.

EMBO Mol Med. 2018 Apr;10(4). pii: e7918. doi: 10.15252/emmm.201707918.


Endogenous IL-33 Contributes to Kidney Ischemia-Reperfusion Injury as an Alarmin.

Ferhat M, Robin A, Giraud S, Sena S, Goujon JM, Touchard G, Hauet T, Girard JP, Gombert JM, Herbelin A, Thierry A.

J Am Soc Nephrol. 2018 Apr;29(4):1272-1288. doi: 10.1681/ASN.2017060650. Epub 2018 Feb 7.


Predictive factors of spontaneous CMV DNAemia clearance in kidney transplantation.

Noble J, Gatault P, Sautenet B, Gaudy-Graffin C, Beby-Defaux A, Thierry A, Essig M, Halimi JM, Munteanu E, Alain S, Buchler M.

J Clin Virol. 2018 Feb - Mar;99-100:38-43. doi: 10.1016/j.jcv.2017.12.011. Epub 2017 Dec 29.


Recurrence of Renal Cell Cancer After Renal Transplantation in a Multicenter French Cohort.

Cognard N, Anglicheau D, Gatault P, Girerd S, Essig M, Hurault de Ligny B, Le Meur Y, Le Roy F, Garrouste C, Thierry A, Colosio C, Rivalan J, Sayegh J, Choukroun G, Moulin B, Caillard S.

Transplantation. 2018 May;102(5):860-867. doi: 10.1097/TP.0000000000002009.


IL-33 receptor ST2 deficiency attenuates renal ischaemia-reperfusion injury in euglycaemic, but not streptozotocin-induced hyperglycaemic mice.

Sehnine M, Ferhat M, Sena S, Gombert JM, Goujon JM, Thierry A, Touchard G, Hauet T, Herbelin A, Hadjadj S.

Diabetes Metab. 2018 Feb;44(1):55-60. doi: 10.1016/j.diabet.2017.06.008. Epub 2017 Sep 12.


Clinical utility of circulating DNA analysis for rapid detection of actionable mutations to select metastatic colorectal patients for anti-EGFR treatment.

Thierry AR, El Messaoudi S, Mollevi C, Raoul JL, Guimbaud R, Pezet D, Artru P, Assenat E, Borg C, Mathonnet M, De La Fouchardière C, Bouché O, Gavoille C, Fiess C, Auzemery B, Meddeb R, Lopez-Crapez E, Sanchez C, Pastor B, Ychou M.

Ann Oncol. 2017 Sep 1;28(9):2149-2159. doi: 10.1093/annonc/mdx330.


[From the perinatal period to adolescence: the three stages of coordination].

Thierry A, Laplace S, Gourbil A, Saint-André S.

Soins Psychiatr. 2017 Sep - Oct;38(312):16-19. doi: 10.1016/j.spsy.2017.06.006. French.


Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle.

Lazar-Stefanita L, Scolari VF, Mercy G, Muller H, Guérin TM, Thierry A, Mozziconacci J, Koszul R.

EMBO J. 2017 Sep 15;36(18):2684-2697. doi: 10.15252/embj.201797342. Epub 2017 Jul 20.


Strains of the Lactobacillus casei group show diverse abilities for the production of flavor compounds in 2 model systems.

Stefanovic E, Thierry A, Maillard MB, Bertuzzi A, Rea MC, Fitzgerald G, McAuliffe O, Kilcawley KN.

J Dairy Sci. 2017 Sep;100(9):6918-6929. doi: 10.3168/jds.2016-12408. Epub 2017 Jul 12.


Antifungal Microbial Agents for Food Biopreservation-A Review.

Leyva Salas M, Mounier J, Valence F, Coton M, Thierry A, Coton E.

Microorganisms. 2017 Jul 8;5(3). pii: E37. doi: 10.3390/microorganisms5030037. Review.


An adjustable predictive score of graft survival in kidney transplant patients and the levels of risk linked to de novo donor-specific anti-HLA antibodies.

Prémaud A, Filloux M, Gatault P, Thierry A, Büchler M, Munteanu E, Marquet P, Essig M, Rousseau A.

PLoS One. 2017 Jul 3;12(7):e0180236. doi: 10.1371/journal.pone.0180236. eCollection 2017.


Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.

Thierry AR, Pastor B, Jiang ZQ, Katsiampoura AD, Parseghian C, Loree JM, Overman MJ, Sanchez C, Messaoudi SE, Ychou M, Kopetz S.

Clin Cancer Res. 2017 Aug 15;23(16):4578-4591. doi: 10.1158/1078-0432.CCR-17-0232. Epub 2017 Apr 11.


Specific expression of heme oxygenase-1 by myeloid cells modulates renal ischemia-reperfusion injury.

Rossi M, Thierry A, Delbauve S, Preyat N, Soares MP, Roumeguère T, Leo O, Flamand V, Le Moine A, Hougardy JM.

Sci Rep. 2017 Mar 15;7(1):197. doi: 10.1038/s41598-017-00220-w.


3D organization of synthetic and scrambled chromosomes.

Mercy G, Mozziconacci J, Scolari VF, Yang K, Zhao G, Thierry A, Luo Y, Mitchell LA, Shen M, Shen Y, Walker R, Zhang W, Wu Y, Xie ZX, Luo Z, Cai Y, Dai J, Yang H, Yuan YJ, Boeke JD, Bader JS, Muller H, Koszul R.

Science. 2017 Mar 10;355(6329). pii: eaaf4597. doi: 10.1126/science.aaf4597.


Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.

Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Pastor B, Ychou M, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Thierry AR, Gallick GE, Kopetz S.

Clin Cancer Res. 2017 Aug 1;23(15):4146-4154. doi: 10.1158/1078-0432.CCR-16-3138. Epub 2017 Mar 9.


Assessing frost damages using dynamic models in walnut trees: exposure rather than vulnerability controls frost risks.

Guillaume C, Isabelle C, Marc B, Thierry A.

Plant Cell Environ. 2018 May;41(5):1008-1021. doi: 10.1111/pce.12935. Epub 2017 Apr 19.


Factors associated with carriage of carbapenem-non-susceptible Enterobacteriaceaein North-Eastern France and outcomes of infected patients.

Muggeo A, Guillard T, Barbe C, Thierry A, Bajolet O, Vernet-Garnier V, Limelette A, Brasme L, De Champs C; CARBAFREST Group.

J Antimicrob Chemother. 2017 May 1;72(5):1496-1501. doi: 10.1093/jac/dkw590.


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