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Items: 1 to 50 of 441

1.

Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.

O'Riordan CE, Purvis GSD, Collotta D, Chiazza F, Wissuwa B, Al Zoubi S, Stiehler L, Martin L, Coldewey SM, Collino M, Thiemermann C.

Front Immunol. 2019 Sep 6;10:2129. doi: 10.3389/fimmu.2019.02129. eCollection 2019.

2.

Response.

Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T.

Chest. 2019 Sep;156(3):636-637. doi: 10.1016/j.chest.2019.05.013. No abstract available.

PMID:
31511159
3.

Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale.

Randall DW, Kieswich J, Swann J, McCafferty K, Thiemermann C, Curtis M, Hoyles L, Yaqoob MM.

Microbiome. 2019 Sep 2;7(1):127. doi: 10.1186/s40168-019-0738-y.

4.

Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock.

Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J, Collino M, Thiemermann C.

Ann Surg. 2019 Jun 7. doi: 10.1097/SLA.0000000000003407. [Epub ahead of print]

PMID:
31188196
5.

Annexin-A1: Therapeutic Potential in Microvascular Disease.

Purvis GSD, Solito E, Thiemermann C.

Front Immunol. 2019 Apr 30;10:938. doi: 10.3389/fimmu.2019.00938. eCollection 2019. Review.

6.

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.

Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D, Cento A, Mastrocola R, Aragno M, Cutrin JC, Reutelingsperger C, Grigore L, Catapano AL, Yaqoob MM, Norata GD, Solito E, Thiemermann C.

Front Immunol. 2019 Mar 27;10:571. doi: 10.3389/fimmu.2019.00571. eCollection 2019.

7.

Response.

Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T.

Chest. 2019 Mar;155(3):647-648. doi: 10.1016/j.chest.2018.10.018. No abstract available.

8.

Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury.

Voisin MB, Leoni G, Woodfin A, Loumagne L, Patel NS, Di Paola R, Cuzzocrea S, Thiemermann C, Perretti M, Nourshargh S.

J Pathol. 2019 May;248(1):88-102. doi: 10.1002/path.5234. Epub 2019 Mar 22.

9.

Linagliptin Attenuates the Cardiac Dysfunction Associated With Experimental Sepsis in Mice With Pre-existing Type 2 Diabetes by Inhibiting NF-κB.

Al Zoubi S, Chen J, Murphy C, Martin L, Chiazza F, Collotta D, Yaqoob MM, Collino M, Thiemermann C.

Front Immunol. 2018 Dec 18;9:2996. doi: 10.3389/fimmu.2018.02996. eCollection 2018.

10.

The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling.

Andrikopoulos P, Kieswich J, Pacheco S, Nadarajah L, Harwood SM, O'Riordan CE, Thiemermann C, Yaqoob MM.

J Am Soc Nephrol. 2019 Jan;30(1):33-49. doi: 10.1681/ASN.2018020209. Epub 2018 Dec 10.

PMID:
30530834
11.

A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain.

Kieswich JE, Chen J, Alliouachene S, Caton PW, McCafferty K, Thiemermann C, Yaqoob MM.

BMC Nephrol. 2018 Dec 4;19(1):346. doi: 10.1186/s12882-018-1155-3.

12.

The Response to the Letter to the Editor Titled: "Is Triple Self-plagiarism "OK" If Only Made Transparent?" by Volker R Jacobs, MD, MBA.

Osuchowski MF, Hellman J, Huber-Lang M, Libert C, Remick DG, Thiemermann C, Zingarelli B.

Shock. 2019 Jan;51(1):140-141. doi: 10.1097/SHK.0000000000001294. No abstract available.

PMID:
30475325
13.

Retraction notice to "Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury" [Int. J. Cardiol. 163 (2013) 326-334].

Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A, Suzuki H, Thiemermann C, Knight RA, Latchman DS, Stephanou A.

Int J Cardiol. 2019 Jan 1;274:404. doi: 10.1016/j.ijcard.2018.10.031. No abstract available.

14.

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Infection. 2018 Oct;46(5):745-747. doi: 10.1007/s15010-018-1197-2.

15.

The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications.

Martin L, Derwall M, Al Zoubi S, Zechendorf E, Reuter DA, Thiemermann C, Schuerholz T.

Chest. 2019 Feb;155(2):427-437. doi: 10.1016/j.chest.2018.08.1037. Epub 2018 Aug 29. Review.

PMID:
30171861
16.

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Intensive Care Med Exp. 2018 Aug 14;6(1):26. doi: 10.1186/s40635-018-0189-y. Review.

17.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman CS, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Shock. 2018 Oct;50(4):377-380. doi: 10.1097/SHK.0000000000001212.

18.

Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints.

Zingarelli B, Coopersmith CM, Drechsler S, Efron P, Marshall JC, Moldawer L, Wiersinga WJ, Xiao X, Osuchowski MF, Thiemermann C.

Shock. 2019 Jan;51(1):10-22. doi: 10.1097/SHK.0000000000001243.

PMID:
30106874
19.

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.

Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.

Infection. 2018 Oct;46(5):687-691. doi: 10.1007/s15010-018-1183-8. Review. Erratum in: Infection. 2018 Sep 17;:.

20.

Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage.

Aswani A, Manson J, Itagaki K, Chiazza F, Collino M, Wupeng WL, Chan TK, Wong WSF, Hauser CJ, Thiemermann C, Brohi K.

Front Immunol. 2018 May 8;9:891. doi: 10.3389/fimmu.2018.00891. eCollection 2018.

21.

The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction.

Khan AI, Kapoor A, Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M, Thiemermann C.

Shock. 2018 Jun;49(6):675-681. doi: 10.1097/SHK.0000000000000963.

PMID:
29757923
22.

Delayed activation of PPAR-β/δ improves long-term survival in mouse sepsis: effects on organ inflammation and coagulation.

Busch D, Kapoor A, Rademann P, Hildebrand F, Bahrami S, Thiemermann C, Osuchowski MF.

Innate Immun. 2018 May;24(4):262-273. doi: 10.1177/1753425918771748. Epub 2018 Apr 26.

23.

Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning.

Zechendorf E, Vaßen P, Zhang J, Hallawa A, Martincuks A, Krenkel O, Müller-Newen G, Schuerholz T, Simon TP, Marx G, Ascheid G, Schmeink A, Dartmann G, Thiemermann C, Martin L.

Front Immunol. 2018 Mar 20;9:393. doi: 10.3389/fimmu.2018.00393. eCollection 2018.

24.

Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis.

Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C, Ahluwalia A.

FASEB J. 2018 Jul;32(7):3816-3831. doi: 10.1096/fj.201701303R. Epub 2018 Feb 20.

PMID:
29465314
25.

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes.

Purvis GSD, Chiazza F, Chen J, Azevedo-Loiola R, Martin L, Kusters DHM, Reutelingsperger C, Fountoulakis N, Gnudi L, Yaqoob MM, Collino M, Thiemermann C, Solito E.

Diabetologia. 2018 Feb;61(2):482-495. doi: 10.1007/s00125-017-4469-y. Epub 2017 Oct 30.

26.

Mitochondrial DNA in Acute Kidney Injury: Chicken or Egg?

Martin L, Thiemermann C.

Shock. 2018 Mar;49(3):352-353. doi: 10.1097/SHK.0000000000000966. No abstract available.

PMID:
28817466
27.

The Anti-Malarial Drug Artesunate Attenuates Cardiac Injury in a Rodent Model of Myocardial Infarction.

Khan AI, Kapoor A, Che J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M, Thiemermann C.

Shock. 2017 Aug 9. doi: 10.1097/SHK.0000000000000963. [Epub ahead of print]

28.

[Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy].

Martin L, Derwall M, Thiemermann C, Schürholz T.

Anaesthesist. 2017 Jul;66(7):479-490. doi: 10.1007/s00101-017-0329-x. Review. German.

PMID:
28677016
29.

Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis.

Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV, Collino M, Yaqoob MM, Thiemermann C.

J Am Heart Assoc. 2017 Jul 3;6(7). pii: e005092. doi: 10.1161/JAHA.116.005092.

30.

The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men.

Martin L, Gombert A, Chen J, Liebens J, Verleger J, Kalder J, Marx G, Jacobs M, Thiemermann C, Schuerholz T.

Front Immunol. 2017 Jun 12;8:681. doi: 10.3389/fimmu.2017.00681. eCollection 2017.

31.

Modeling Acute Traumatic Hemorrhagic Shock Injury: Challenges and Guidelines for Preclinical Studies.

Tremoleda JL, Watts SA, Reynolds PS, Thiemermann C, Brohi K.

Shock. 2017 Dec;48(6):610-623. doi: 10.1097/SHK.0000000000000901. Review.

PMID:
28509685
32.

Sepsis-3 on the Block: What Does It Mean for Preclinical Sepsis Modeling?

Osuchowski MF, Thiemermann C, Remick DG.

Shock. 2017 May;47(5):658-660. doi: 10.1097/SHK.0000000000000775.

33.

Relative Adrenal Insufficiency in Cardiogenic Shock: Is There a Need for Action?

Briegel J, Möhnle P, Vogeser M, Thiemermann C, Radermacher P.

Shock. 2017 Oct;48(4):498-499. doi: 10.1097/SHK.0000000000000870. No abstract available.

PMID:
28362713
34.

Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock.

Yamada N, Martin LB, Zechendorf E, Purvis GSD, Chiazza F, Varrone B, Collino M, Shepherd J, Heinbockel L, Gutsmann T, Correa W, Brandenburg K, Marx G, Schuerholz T, Brohi K, Thiemermann C.

Ann Surg. 2018 Aug;268(2):348-356. doi: 10.1097/SLA.0000000000002186.

35.

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation.

Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NS, Barnes MR, Brohi K, Collino M, Thiemermann C.

Ann Surg. 2017 Feb;265(2):408-417. doi: 10.1097/SLA.0000000000001664.

36.

The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis.

Martin L, Horst K, Chiazza F, Oggero S, Collino M, Brandenburg K, Hildebrand F, Marx G, Thiemermann C, Schuerholz T.

Sci Rep. 2016 Nov 17;6:37277. doi: 10.1038/srep37277.

37.

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy.

Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C, Brohi K.

Anesthesiology. 2017 Jan;126(1):115-127.

38.

Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water.

de Jesus Gaffney V, Mota-Filipe H, Pinto RA, Thiemermann C, Loureiro M, Cardoso VV, Benoliel MJ, Almeida CM.

Environ Toxicol Chem. 2016 Nov;35(11):2674-2682. doi: 10.1002/etc.3451. Epub 2016 Jul 7.

PMID:
27061931
39.

Oxygen in the Heart: How Much is too Much?

Kalbitz M, Waller C, Huber-Lang M, Gebhard F, Thiemermann C, Radermacher P.

Shock. 2017 Apr;47(4):531-532. doi: 10.1097/SHK.0000000000000760. No abstract available.

PMID:
27749760
40.

Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis.

Coldewey SM, Benetti E, Collino M, Pfeilschifter J, Sponholz C, Bauer M, Huwiler A, Thiemermann C.

Sci Rep. 2016 Jun 9;6:27594. doi: 10.1038/srep27594.

41.

Selenium and Niacin for Sepsis Therapy: The Sum Is Greater Than Its Parts.

Chen J, Thiemermann C.

Crit Care Med. 2016 Jun;44(6):1256-7. doi: 10.1097/CCM.0000000000001493. No abstract available.

PMID:
27182867
42.

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

Chen J, Kieswich JE, Chiazza F, Moyes AJ, Gobbetti T, Purvis GS, Salvatori DC, Patel NS, Perretti M, Hobbs AJ, Collino M, Yaqoob MM, Thiemermann C.

J Am Soc Nephrol. 2017 Jan;28(1):94-105. doi: 10.1681/ASN.2015060670. Epub 2016 May 6.

43.

Norepinephrine, the Intensivist's Swiss Army Knife for Circulatory Shock?

Asfar P, Thiemermann C, Radermacher P.

Shock. 2016 Jul;46(1):106-7. doi: 10.1097/SHK.0000000000000590. No abstract available.

PMID:
26885713
44.

Neuronal Nitric Oxide Synthase is Involved in Vascular Hyporeactivity and Multiple Organ Dysfunction Associated with Hemorrhagic Shock.

Sordi R, Chiazza F, Collino M, Assreuy J, Thiemermann C.

Shock. 2016 May;45(5):525-33. doi: 10.1097/SHK.0000000000000533.

45.

Targeting the NLRP3 Inflammasome to Reduce Diet-Induced Metabolic Abnormalities in Mice.

Chiazza F, Couturier-Maillard A, Benetti E, Mastrocola R, Nigro D, Cutrin JC, Serpe L, Aragno M, Fantozzi R, Ryffel B, Thiemermann C, Collino M.

Mol Med. 2016 Mar;21(1):1025-1037. doi: 10.2119/molmed.2015.00104. Epub 2016 May 9.

46.

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states.

Madalli S, Beyrau M, Whiteford J, Duchene J, Singh Nandhra I, Patel NS, Motwani MP, Gilroy DW, Thiemermann C, Nourshargh S, Scotland RS.

Biol Sex Differ. 2015 Nov 26;6:27. doi: 10.1186/s13293-015-0047-5. eCollection 2015.

47.

Does Insulin Protect the Brain in Mice and Man with Sepsis?

Hache G, Osuchowski M, Thiemermann C.

Shock. 2015 Sep;44(3):287. doi: 10.1097/SHK.0000000000000423. No abstract available.

PMID:
26274365
48.

Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock.

Sordi R, Chiazza F, Johnson FL, Patel NS, Brohi K, Collino M, Thiemermann C.

Mol Med. 2015 Jun 18;21:563-75. doi: 10.2119/molmed.2015.00049.

49.

'Preconditioning' with low dose lipopolysaccharide aggravates the organ injury / dysfunction caused by hemorrhagic shock in rats.

Sordi R, Chiazza F, Patel NS, Doyle RA, Collino M, Thiemermann C.

PLoS One. 2015 Apr 1;10(4):e0122096. doi: 10.1371/journal.pone.0122096. eCollection 2015.

50.

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin.

Collino M, Thiemermann C, Cerami A, Brines M.

Pharmacol Ther. 2015 Jul;151:32-40. doi: 10.1016/j.pharmthera.2015.02.005. Epub 2015 Feb 26. Review.

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