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Items: 20

1.

An RNA Aptamer-Based Biomarker Platform Demonstrates High Soluble CD25 Occupancy by IL2 in the Serum of Follicular Lymphoma Patients.

Veeramani S, Blackwell SE, Thiel WH, Yang ZZ, Ansell SM, Giangrande PH, Weiner GJ.

Cancer Immunol Res. 2019 Sep;7(9):1511-1522. doi: 10.1158/2326-6066.CIR-18-0821. Epub 2019 Aug 5.

PMID:
31383650
2.

Delivery of Cell-Specific Aptamers to the Arterial Wall with an Occlusion Perfusion Catheter.

Udofot O, Lin LH, Thiel WH, Erwin M, Turner E, Miller FJ Jr, Giangrande PH, Yazdani SK.

Mol Ther Nucleic Acids. 2019 Jun 7;16:360-366. doi: 10.1016/j.omtn.2019.03.005. Epub 2019 Mar 23.

3.

Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations.

Meng X, Yang S, Li Y, Li Y, Devor EJ, Bi J, Wang X, Umesalma S, Quelle DE, Thiel WH, Thiel KW, Leslie KK.

Dis Markers. 2018 Dec 17;2018:3810108. doi: 10.1155/2018/3810108. eCollection 2018.

4.

RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome.

Urak KT, Blanco GN, Shubham S, Lin LH, Dassie JP, Thiel WH, Chen Y, Sonkar VK, Lei B, Murthy S, Gutierrez WR, Wilson ME, Stiber JA, Klesney-Tait J, Dayal S, Miller FJ Jr, Giangrande PH.

Nat Commun. 2019 Jan 10;10(1):116. doi: 10.1038/s41467-018-08030-y.

5.

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator.

Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, Hall D, Wu J, Shi Y, Zhu Q, Chen C, Thiel WH, Zhan X, Weiss RM, Zhan F, Musselman CA, Pufall M, Zhu W, Au KF, Hong J, Anderson ME, Grueter CE, Song LS.

Science. 2018 Dec 21;362(6421). pii: eaan3303. doi: 10.1126/science.aan3303. Epub 2018 Nov 8.

PMID:
30409805
6.

Aptamers as Diagnostic Tools in Cancer.

Ruiz Ciancio D, Vargas MR, Thiel WH, Bruno MA, Giangrande PH, Mestre MB.

Pharmaceuticals (Basel). 2018 Sep 11;11(3). pii: E86. doi: 10.3390/ph11030086. Review.

7.

CaMKII (Ca2+/Calmodulin-Dependent Kinase II) in Mitochondria of Smooth Muscle Cells Controls Mitochondrial Mobility, Migration, and Neointima Formation.

Nguyen EK, Koval OM, Noble P, Broadhurst K, Allamargot C, Wu M, Strack S, Thiel WH, Grumbach IM.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):1333-1345. doi: 10.1161/ATVBAHA.118.310951. Epub 2018 Mar 29.

8.

Galaxy Workflows for Web-based Bioinformatics Analysis of Aptamer High-throughput Sequencing Data.

Thiel WH.

Mol Ther Nucleic Acids. 2016;5:e345. doi: 10.1038/mtna.2016.54.

9.

AFBI assay - Aptamer Fluorescence Binding and Internalization assay for cultured adherent cells.

Thiel WH, Giangrande PH.

Methods. 2016 Jul 1;103:180-7. doi: 10.1016/j.ymeth.2016.03.005. Epub 2016 Mar 10.

10.

Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation.

Thiel WH, Esposito CL, Dickey DD, Dassie JP, Long ME, Adam J, Streeter J, Schickling B, Takapoo M, Flenker KS, Klesney-Tait J, Franciscis Vd, Miller FJ Jr, Giangrande PH.

Mol Ther. 2016 Apr;24(4):779-87. doi: 10.1038/mt.2015.235. Epub 2016 Jan 6.

11.

Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research.

Thiel WH, Giangrande PH.

Methods. 2016 Mar 15;97:3-10. doi: 10.1016/j.ymeth.2015.10.008. Epub 2015 Oct 23.

12.

Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells.

Thiel WH, Thiel KW, Flenker KS, Bair T, Dupuy AJ, McNamara JO 2nd, Miller FJ, Giangrande PH.

Methods Mol Biol. 2015;1218:187-99. doi: 10.1007/978-1-4939-1538-5_11.

13.

Phosphorylation of Nox1 regulates association with NoxA1 activation domain.

Streeter J, Schickling BM, Jiang S, Stanic B, Thiel WH, Gakhar L, Houtman JC, Miller FJ Jr.

Circ Res. 2014 Nov 7;115(11):911-8. doi: 10.1161/CIRCRESAHA.115.304267. Epub 2014 Sep 16.

14.

Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells.

Gourronc FA, Rockey WM, Thiel WH, Giangrande PH, Klingelhutz AJ.

Virology. 2013 Nov;446(1-2):325-33. doi: 10.1016/j.virol.2013.08.015. Epub 2013 Sep 8.

15.

Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection.

Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ Jr, Giangrande PH.

PLoS One. 2012;7(9):e43836. doi: 10.1371/journal.pone.0043836. Epub 2012 Sep 4.

16.

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.

Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO 2nd, Giangrande PH.

Nucleic Acids Res. 2012 Jul;40(13):6319-37. doi: 10.1093/nar/gks294. Epub 2012 Mar 30.

17.

Nucleotide bias observed with a short SELEX RNA aptamer library.

Thiel WH, Bair T, Wyatt Thiel K, Dassie JP, Rockey WM, Howell CA, Liu XY, Dupuy AJ, Huang L, Owczarzy R, Behlke MA, McNamara JO, Giangrande PH.

Nucleic Acid Ther. 2011 Aug;21(4):253-63. doi: 10.1089/nat.2011.0288. Epub 2011 Jun 28.

18.

Proarrhythmic defects in Timothy syndrome require calmodulin kinase II.

Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, Anderson ME.

Circulation. 2008 Nov 25;118(22):2225-34. doi: 10.1161/CIRCULATIONAHA.108.788067. Epub 2008 Nov 10.

19.

Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating.

Low CM, Lyuboslavsky P, French A, Le P, Wyatte K, Thiel WH, Marchan EM, Igarashi K, Kashiwagi K, Gernert K, Williams K, Traynelis SF, Zheng F.

Mol Pharmacol. 2003 Jun;63(6):1212-22.

PMID:
12761330
20.

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