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Complete Genome Sequence of Raoultella electrica 1GB (DSM 102253T), Isolated from Anodic Biofilms of a Glucose-Fed Microbial Fuel Cell.

Thiel S, Bunk B, Spröer C, Overmann J, Jahn D, Biedendieck R.

Microbiol Resour Announc. 2019 Oct 24;8(43). pii: e00800-19. doi: 10.1128/MRA.00800-19.


Prevalence of Obstructive Sleep Apnea in Patients with Thoracic Aortic Aneurysm: A Prospective, Parallel Cohort Study.

Gaisl T, Baumgartner P, Rejmer P, Osswald M, Roeder M, Thiel S, Stämpfli SF, Clarenbach CF, Tanner FC, Kohler M.

Respiration. 2019 Sep 25:1-9. doi: 10.1159/000502892. [Epub ahead of print]


The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials.

Bro-Jeppesen J, Jeppesen AN, Haugaard S, Troldborg A, Hassager C, Kjaergaard J, Kirkegaard H, Wanscher M, Hvas AM, Thiel S.

Eur Heart J Acute Cardiovasc Care. 2019 Sep 20:2048872619870031. doi: 10.1177/2048872619870031. [Epub ahead of print]


Impact of hypertension on cerebral microvascular structure in CPAP-treated obstructive sleep apnoea patients: a diffusion magnetic resonance imaging study.

Thiel S, Gaisl T, Lettau F, Boss A, Winklhofer S, Kohler M, Rossi C.

Neuroradiology. 2019 Dec;61(12):1437-1445. doi: 10.1007/s00234-019-02292-z. Epub 2019 Sep 16.


Plasma levels of H- and L-ficolin are increased in axial spondyloarthritis: improvement of disease identification.

Troldborg A, Thiel S, Mistegaard CE, Hansen A, Korsholm TL, Stengaard-Pedersen K, Loft AG.

Clin Exp Immunol. 2019 Sep 13. doi: 10.1111/cei.13374. [Epub ahead of print]


Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.

Pedersen DV, Gadeberg TAF, Thomas C, Wang Y, Joram N, Jensen RK, Mazarakis SMM, Revel M, El Sissy C, Petersen SV, Lindorff-Larsen K, Thiel S, Laursen NS, Fremeaux-Bacchi V, Andersen GR.

Front Immunol. 2019 Aug 22;10:2007. doi: 10.3389/fimmu.2019.02007. eCollection 2019.


Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort.

Glerup M, Thiel S, Rypdal V, Arnstad ED, Ekelund M, Peltoniemi S, Aalto K, Rygg M, Nielsen S, Fasth A, Berntson L, Nordal E, Herlin T; Nordic Study Group of Pediatric Rheumatology (NoSPeR).

Pediatr Rheumatol Online J. 2019 Sep 9;17(1):63. doi: 10.1186/s12969-019-0367-9.


Endocrine responses during CPAP withdrawal in obstructive sleep apnoea: data from two randomised controlled trials.

Thiel S, Haile SR, Peitzsch M, Schwarz EI, Sievi NA, Kurth S, Beuschlein F, Kohler M, Gaisl T.

Thorax. 2019 Nov;74(11):1102-1105. doi: 10.1136/thoraxjnl-2019-213522. Epub 2019 Aug 29.


Pattern Recognition Molecules of the Lectin Pathway-Screening of Patients with Suspected Immunodeficiency.

Jørgensen CM, Jensen L, Christiansen M, Bjerre M, Jensen JMB, Thiel S.

J Clin Immunol. 2019 Oct;39(7):668-677. doi: 10.1007/s10875-019-00675-8. Epub 2019 Aug 3.


Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology.

Almendros I, Baillieul S, Caballero C, Degani-Costa LH, Furian M, Hirotsu C, Louvaris Z, Thiel S, Turnbull CD.

ERJ Open Res. 2019 Jul 8;5(3). pii: 00201-2018. doi: 10.1183/23120541.00201-2018. eCollection 2019 Jul.


Effect of long-term remote ischemic conditioning on inflammation and cardiac remodeling.

Pryds K, Rahbek Schmidt M, Bjerre M, Thiel S, Refsgaard J, Bøtker HE, Drage Østgård R, Ranghøj Nielsen R.

Scand Cardiovasc J. 2019 Aug;53(4):183-191. doi: 10.1080/14017431.2019.1622770. Epub 2019 Jun 5.


Circulating lectin pathway proteins do not predict short-term cardiac outcomes after myocardial infarction.

Holt CB, Østergaard JA, Thiel S, Hansen TK, Mellbin L, Sörensson P, Bjerre M.

Clin Exp Immunol. 2019 Oct;198(1):94-100. doi: 10.1111/cei.13315. Epub 2019 Jun 3.


Efficacy of pharmacotherapy for OSA in adults: A systematic review and network meta-analysis.

Gaisl T, Haile SR, Thiel S, Osswald M, Kohler M.

Sleep Med Rev. 2019 Aug;46:74-86. doi: 10.1016/j.smrv.2019.04.009. Epub 2019 Apr 19. Review.


Ficolin-3 Deficiency Is Associated with Disease and an Increased Risk of Systemic Lupus Erythematosus.

Troldborg A, Steffensen R, Trendelenburg M, Hauser T, Winther KG, Hansen AG, Stengaard-Pedersen K, Voss A, Thiel S.

J Clin Immunol. 2019 May;39(4):421-429. doi: 10.1007/s10875-019-00627-2. Epub 2019 May 1.


Clinical Experience of Immunotherapy Treatment: Efficacy and Toxicity Analysis of the Compassionate Use Program of Nivolumab in Patients with Advanced Squamous Cell Non-Small Cell Lung Cancer.

Krefting F, Basara N, Schütte W, Späth-Schwalbe E, Alt J, Thiel S, Kimmich M, Fischer JR, Kurz S, Griesinger F, Christoph DC.

Oncol Res Treat. 2019;42(5):243-255. doi: 10.1159/000499321. Epub 2019 Apr 17.


Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock.

Larsen JB, Laursen MA, Hvas CL, Larsen KM, Thiel S, Hvas AM.

Thromb Haemost. 2019 Jun;119(6):952-961. doi: 10.1055/s-0039-1685140. Epub 2019 Apr 15.


Return of sleep apnoea and sleep fragmentation following CPAP withdrawal in patients with obstructive sleep apnoea.

Turnbull C, Pattenden S, Gaisl T, Rossi V, Thiel S, Kohler M, Stradling J.

Eur Respir J. 2019 May 9;53(5). pii: 1802351. doi: 10.1183/13993003.02351-2018. Print 2019 May. No abstract available.


Factors involved in initiation and regulation of complement lectin pathway influence postoperative outcome after pediatric cardiac surgery involving cardiopulmonary bypass.

Michalski M, Pągowska-Klimek I, Thiel S, Świerzko AS, Hansen AG, Jensenius JC, Cedzyński M.

Sci Rep. 2019 Feb 27;9(1):2930. doi: 10.1038/s41598-019-39742-w.


Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia.

Larsen JB, Andersen AS, Hvas CL, Thiel S, Lassen MR, Hvas AM, Hansen AT.

Am J Reprod Immunol. 2019 Apr;81(4):e13092. doi: 10.1111/aji.13092. Epub 2019 Feb 23.


A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein.

Yatime L, Merle NS, Hansen AG, Friis NA, Østergaard JA, Bjerre M, Roumenina LT, Thiel S, Kristensen P, Andersen GR.

Front Immunol. 2018 Nov 29;9:2822. doi: 10.3389/fimmu.2018.02822. eCollection 2018.


MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression.

Maestri CA, Nisihara R, Mendes HW, Jensenius J, Thiel S, Messias-Reason I, de Carvalho NS.

Front Immunol. 2018 Nov 23;9:2742. doi: 10.3389/fimmu.2018.02742. eCollection 2018.


Effects of short-term continuous positive airway pressure withdrawal on cerebral vascular reactivity measured by blood oxygen level-dependent magnetic resonance imaging in obstructive sleep apnoea: a randomised controlled trial.

Thiel S, Lettau F, Rejmer P, Rossi C, Haile SR, Schwarz EI, Stöberl AS, Sievi NA, Boss A, Becker AS, Winklhofer S, Stradling JR, Kohler M.

Eur Respir J. 2019 Feb 21;53(2). pii: 1801854. doi: 10.1183/13993003.01854-2018. Print 2019 Feb.


To Scan or Not to Scan: Overutilization of Computed Tomography for Minor Head Injury at a Pediatric Trauma Center.

Kauffman JD, Litz CN, Thiel SA, Nguyen ATH, Carey A, Danielson PD, Chandler NM.

J Surg Res. 2018 Dec;232:164-170. doi: 10.1016/j.jss.2018.06.005. Epub 2018 Jul 5.


Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis.

Banda NK, Desai D, Scheinman RI, Pihl R, Sekine H, Fujita T, Sharma V, Hansen AG, Garred P, Thiel S, Borodovsky A, Holers VM.

Immunohorizons. 2018 Sep;2(8):274-295. doi: 10.4049/immunohorizons.1800053.


Ficolin-1 and Ficolin-3 Plasma Levels Are Altered in HIV and HIV/HCV Coinfected Patients From Southern Brazil.

Tizzot MR, Lidani KCF, Andrade FA, Mendes HW, Beltrame MH, Reiche E, Thiel S, Jensenius JC, de Messias-Reason IJ.

Front Immunol. 2018 Oct 8;9:2292. doi: 10.3389/fimmu.2018.02292. eCollection 2018.


The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT).

Świerzko AS, Michalski M, Sokołowska A, Nowicki M, Eppa Ł, Szala-Poździej A, Mitrus I, Szmigielska-Kapłon A, Sobczyk-Kruszelnicka M, Michalak K, Gołos A, Wierzbowska A, Giebel S, Jamroziak K, Kowalski ML, Brzezińska O, Thiel S, Jensenius JC, Kasperkiewicz K, Cedzyński M.

Front Immunol. 2018 Sep 20;9:2153. doi: 10.3389/fimmu.2018.02153. eCollection 2018.


Retrospective Evaluation of Clinical Signs and Gross Pathologic Findings in Birds Infected With Mycobacterium genavense.

Schmitz A, Rinder M, Thiel S, Peschel A, Moser K, Reese S, Korbel R.

J Avian Med Surg. 2018 Sep;32(3):194-204. doi: 10.1647/2017-261.


The crustal geophysical signature of a world-class magmatic mineral system.

Heinson G, Didana Y, Soeffky P, Thiel S, Wise T.

Sci Rep. 2018 Jul 13;8(1):10608. doi: 10.1038/s41598-018-29016-2.


The Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus.

Troldborg A, Thiel S, Trendelenburg M, Friebus-Kardash J, Nehring J, Steffensen R, Hansen SWK, Laska MJ, Deleuran B, Jensenius JC, Voss A, Stengaard-Pedersen K.

J Rheumatol. 2018 Aug;45(8):1136-1144. doi: 10.3899/jrheum.171033. Epub 2018 Jun 15.


The complement lectin pathway after cardiac arrest.

Haugaard SF, Jeppesen AN, Troldborg A, Kirkegaard H, Thiel S, Hvas AM.

Scand J Immunol. 2018 Jun 9:e12680. doi: 10.1111/sji.12680. [Epub ahead of print]


Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition.

Medjeral-Thomas NR, Troldborg A, Constantinou N, Lomax-Browne HJ, Hansen AG, Willicombe M, Pusey CD, Cook HT, Thiel S, Pickering MC.

Kidney Int Rep. 2017 Nov 29;3(2):426-438. doi: 10.1016/j.ekir.2017.11.015. eCollection 2018 Mar.


High prevalence of Mycobacterium genavense within flocks of pet birds.

Schmitz A, Korbel R, Thiel S, Wörle B, Gohl C, Rinder M.

Vet Microbiol. 2018 May;218:40-44. doi: 10.1016/j.vetmic.2018.03.026. Epub 2018 Mar 21.


Changes in the Lectin Pathway Following Intracerebral or Spontaneous Subarachnoid Hemorrhage.

Sandgaard E, Troldborg A, Lauridsen SV, Gyldenholm T, Thiel S, Hvas AM.

Mol Neurobiol. 2019 Jan;56(1):78-87. doi: 10.1007/s12035-018-1066-0. Epub 2018 Apr 19.


Models of the complement C1 complex.

Mortensen SA, Sander B, Jensen RK, Pedersen JS, Golas MM, Thiel S, Andersen GR.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3866. doi: 10.1073/pnas.1803577115. Epub 2018 Apr 13. No abstract available.


The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus.

Troldborg A, Jensen L, Deleuran B, Stengaard-Pedersen K, Thiel S, Jensenius JC.

Front Immunol. 2018 Mar 26;9:581. doi: 10.3389/fimmu.2018.00581. eCollection 2018.


Why are some groups physically active and others not? A contrast group analysis in leisure settings.

Thiel A, Thedinga HK, Barkhoff H, Giel K, Schweizer O, Thiel S, Zipfel S.

BMC Public Health. 2018 Mar 20;18(1):377. doi: 10.1186/s12889-018-5283-2.


A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.

Jensen RK, Pihl R, Gadeberg TAF, Jensen JK, Andersen KR, Thiel S, Laursen NS, Andersen GR.

J Biol Chem. 2018 Apr 27;293(17):6269-6281. doi: 10.1074/jbc.RA117.001179. Epub 2018 Mar 1.


Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine.

Christensen R, Heitmann BL, Andersen KW, Nielsen OH, Sørensen SB, Jawhara M, Bygum A, Hvid L, Grauslund J, Wied J, Glerup H, Fredberg U, Villadsen JA, Kjær SG, Fallingborg J, Moghadd SAGR, Knudsen T, Brodersen J, Frøjk J, Dahlerup JF, Bojesen AB, Sorensen GL, Thiel S, Færgeman NJ, Brandslund I, Bennike TB, Stensballe A, Schmidt EB, Franke A, Ellinghaus D, Rosenstiel P, Raes J, Boye M, Werner L, Nielsen CL, Munk HL, Nexøe AB, Ellingsen T, Holmskov U, Kjeldsen J, Andersen V.

BMJ Open. 2018 Feb 8;8(2):e018166. doi: 10.1136/bmjopen-2017-018166.


The lectin pathway and coagulation in lung cancer patients undergoing lobectomy - A randomised controlled trial.

Larsen JB, Troldborg A, Christensen TD, Hvas CL, Thiel S, Hvas AM.

Thromb Res. 2018 Mar;163:92-99. doi: 10.1016/j.thromres.2018.01.042. Epub 2018 Feb 6.


Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism.

Oroszlán G, Dani R, Szilágyi A, Závodszky P, Thiel S, Gál P, Dobó J.

Front Immunol. 2017 Dec 18;8:1821. doi: 10.3389/fimmu.2017.01821. eCollection 2017.


Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes.

Dørflinger GH, Holt CB, Thiel S, Østergaard JA, Hansen TK.

J Diabetes Res. 2017;2017:1249729. doi: 10.1155/2017/1249729. Epub 2017 Nov 26.


Communication of healthcare professionals: Is there ageism?

Schroyen S, Adam S, Marquet M, Jerusalem G, Thiel S, Giraudet AL, Missotten P.

Eur J Cancer Care (Engl). 2018 Jan;27(1). doi: 10.1111/ecc.12780. Epub 2017 Sep 27.


Natalizumab during pregnancy and lactation.

Proschmann U, Thomas K, Thiel S, Hellwig K, Ziemssen T.

Mult Scler. 2018 Oct;24(12):1627-1634. doi: 10.1177/1352458517728813. Epub 2017 Aug 31.


Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement.

Pihl R, Jensen L, Hansen AG, Thøgersen IB, Andres S, Dagnæs-Hansen F, Oexle K, Enghild JJ, Thiel S.

J Immunol. 2017 Aug 9. pii: ji1700518. doi: 10.4049/jimmunol.1700518. [Epub ahead of print]


Global Autorecognition and Activation of Complement by Mannan-Binding Lectin in a Mouse Model of Type 1 Diabetes.

Axelgaard E, Østergaard JA, Haxha S, Thiel S, Hansen TK.

Mediators Inflamm. 2017;2017:9403754. doi: 10.1155/2017/9403754. Epub 2017 Jun 13.


Reply to Arlaud et al.: Structure of the C1 complex and the unbound C1r2s2 tetramer.

Mortensen SA, Sander B, Jensen RK, Pedersen JS, Golas M, Jensenius JC, Hansen AG, Thiel S, Andersen GR.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5768-E5770. doi: 10.1073/pnas.1704353114. Epub 2017 Jul 12. No abstract available.


Use of Hyperlinks in PowerPoint Presentations as an Educational Tool.

Stacy GS, Thiel SG.

Acad Radiol. 2017 Oct;24(10):1318-1324. doi: 10.1016/j.acra.2017.03.018. Epub 2017 May 24.


A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine.

Andersen V, Holmskov U, Sørensen SB, Jawhara M, Andersen KW, Bygum A, Hvid L, Grauslund J, Wied J, Glerup H, Fredberg U, Villadsen JA, Kjær SG, Fallingborg J, Moghadd SAGR, Knudsen T, Brodersen J, Frøjk J, Dahlerup JF, Nielsen OH, Christensen R, Bojesen AB, Sorensen GL, Thiel S, Færgeman NJ, Brandslund I, Stensballe A, Schmidt EB, Franke A, Ellinghaus D, Rosenstiel P, Raes J, Heitmann B, Boye M, Nielsen CL, Werner L, Kjeldsen J, Ellingsen T.

Nutrients. 2017 May 15;9(5). pii: E499. doi: 10.3390/nu9050499.


Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin.

Axelgaard E, Østergaard JA, Thiel S, Hansen TK.

J Diabetes Res. 2017;2017:6368780. doi: 10.1155/2017/6368780. Epub 2017 Feb 28.


Treatment of multiple sclerosis during pregnancy - safety considerations.

Thöne J, Thiel S, Gold R, Hellwig K.

Expert Opin Drug Saf. 2017 May;16(5):523-534. doi: 10.1080/14740338.2017.1311321. Epub 2017 Apr 17. Review.


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