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Items: 1 to 50 of 679

1.

Patients' and public views and attitudes towards the sharing of health data for research: a narrative review of the empirical evidence.

Kalkman S, van Delden J, Banerjee A, Tyl B, Mostert M, van Thiel G.

J Med Ethics. 2019 Nov 12. pii: medethics-2019-105651. doi: 10.1136/medethics-2019-105651. [Epub ahead of print]

2.

In-Hospital Production of Medicines: Preparing for Disruption.

Kalkman S, Arentshorst M, Hoekman J, Boon W, Uijtendaal E, van Thiel G, Moors E.

Trends Biotechnol. 2019 Oct 31. pii: S0167-7799(19)30243-4. doi: 10.1016/j.tibtech.2019.09.011. [Epub ahead of print]

PMID:
31679825
3.

Pharmacological inhibition of TRPM8-induced gene transcription.

Thiel G, Backes TM, Welck J, Steinhausen S, Fischer AL, Langfermann DS, Ulrich M, Wissenbach U, Rössler OG.

Biochem Pharmacol. 2019 Dec;170:113678. doi: 10.1016/j.bcp.2019.113678. Epub 2019 Oct 22.

PMID:
31654626
4.

Regulation of stimulus-induced interleukin-8 gene transcription in human adrenocortical carcinoma cells - Role of AP-1 and NF-κB.

Thiel G, Ulrich M, Mukaida N, Rössler OG.

Cytokine. 2019 Oct 18;126:154862. doi: 10.1016/j.cyto.2019.154862. [Epub ahead of print]

PMID:
31634687
5.

Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling.

Bandmann V, Mirsanaye AS, Schäfer J, Thiel G, Holstein T, Mikosch-Wersching M.

Sci Rep. 2019 Sep 10;9(1):12999. doi: 10.1038/s41598-019-49082-4.

6.

The moral and legal status of Health Care Workers in Cluster Randomized Trials: a response to Weijer and Taljaard.

van der Graaf R, van Thiel GJMW, Hoop EO, Moons KGM, Grobbee DE, van Delden JJM.

J Clin Epidemiol. 2019 Aug 23. pii: S0895-4356(19)30630-4. doi: 10.1016/j.jclinepi.2019.08.005. [Epub ahead of print]

PMID:
31449856
7.

Calcineurin controls gene transcription following stimulation of a Gαq-coupled designer receptor.

Langfermann DS, Schmidt T, Rössler OG, Thiel G.

Exp Cell Res. 2019 Oct 15;383(2):111553. doi: 10.1016/j.yexcr.2019.111553. Epub 2019 Aug 12.

PMID:
31415762
8.

Regulatory sanctions for ethically relevant GCP violations.

Bernabe RC, van Thiel GJMW, Breekveldt NS, Gispen CC, van Delden JJM.

Drug Discov Today. 2019 Nov;24(11):2116-2119. doi: 10.1016/j.drudis.2019.07.001. Epub 2019 Jul 6.

9.

Plants Neither Possess nor Require Consciousness.

Taiz L, Alkon D, Draguhn A, Murphy A, Blatt M, Hawes C, Thiel G, Robinson DG.

Trends Plant Sci. 2019 Aug;24(8):677-687. doi: 10.1016/j.tplants.2019.05.008. Epub 2019 Jul 3. Review.

PMID:
31279732
10.

Minimal Clinically Important Difference and Substantial Clinical Benefit Values for a Pain Visual Analog Scale After Hip Arthroscopy.

Martin RL, Kivlan BR, Christoforetti JJ, Wolff AB, Nho SJ, Salvo JP Jr, Ellis TJ, Van Thiel G, Matsuda D, Carreira DS.

Arthroscopy. 2019 Jul;35(7):2064-2069. doi: 10.1016/j.arthro.2019.02.032. Epub 2019 Jun 14.

PMID:
31208920
11.

PEDIA: prioritization of exome data by image analysis.

Hsieh TC, Mensah MA, Pantel JT, Aguilar D, Bar O, Bayat A, Becerra-Solano L, Bentzen HB, Biskup S, Borisov O, Braaten O, Ciaccio C, Coutelier M, Cremer K, Danyel M, Daschkey S, Eden HD, Devriendt K, Wilson S, Douzgou S, Đukić D, Ehmke N, Fauth C, Fischer-Zirnsak B, Fleischer N, Gabriel H, Graul-Neumann L, Gripp KW, Gurovich Y, Gusina A, Haddad N, Hajjir N, Hanani Y, Hertzberg J, Hoertnagel K, Howell J, Ivanovski I, Kaindl A, Kamphans T, Kamphausen S, Karimov C, Kathom H, Keryan A, Knaus A, Köhler S, Kornak U, Lavrov A, Leitheiser M, Lyon GJ, Mangold E, Reina PM, Carrascal AM, Mitter D, Herrador LM, Nadav G, Nöthen M, Orrico A, Ott CE, Park K, Peterlin B, Pölsler L, Raas-Rothschild A, Randolph L, Revencu N, Fagerberg CR, Robinson PN, Rosnev S, Rudnik S, Rudolf G, Schatz U, Schossig A, Schubach M, Shanoon O, Sheridan E, Smirin-Yosef P, Spielmann M, Suk EK, Sznajer Y, Thiel CT, Thiel G, Verloes A, Vrecar I, Wahl D, Weber I, Winter K, Wiśniewska M, Wollnik B, Yeung MW, Zhao M, Zhu N, Zschocke J, Mundlos S, Horn D, Krawitz PM.

Genet Med. 2019 Jun 5. doi: 10.1038/s41436-019-0566-2. [Epub ahead of print]

PMID:
31164752
12.

A small viral potassium ion channel with an inherent inward rectification.

Eckert D, Schulze T, Stahl J, Rauh O, Van Etten JL, Hertel B, Schroeder I, Moroni A, Thiel G.

Channels (Austin). 2019 Dec;13(1):124-135. doi: 10.1080/19336950.2019.1605813.

13.

The Patient Acceptable Symptomatic State of the 12-Item International Hip Outcome Tool at 1-Year Follow-Up of Hip-Preservation Surgery.

Kivlan BR, Martin RL, Christoforetti JJ, Wolff AB, Nho SJ, Salvo JP Jr, Ellis TJ, Van Thiel G, Matsuda D, Carreira DS.

Arthroscopy. 2019 May;35(5):1457-1462. doi: 10.1016/j.arthro.2018.11.072. Epub 2019 Apr 15.

PMID:
31000393
14.

Narrative medicine as a medical education tool: A systematic review.

Milota MM, van Thiel GJMW, van Delden JJM.

Med Teach. 2019 Jul;41(7):802-810. doi: 10.1080/0142159X.2019.1584274. Epub 2019 Apr 14.

PMID:
30983460
15.

High bandwidth approaches in nanopore and ion channel recordings - A tutorial review.

Hartel AJW, Shekar S, Ong P, Schroeder I, Thiel G, Shepard KL.

Anal Chim Acta. 2019 Jul 11;1061:13-27. doi: 10.1016/j.aca.2019.01.034. Epub 2019 Jan 25. Review.

PMID:
30926031
16.

Responsible data sharing in international health research: a systematic review of principles and norms.

Kalkman S, Mostert M, Gerlinger C, van Delden JJM, van Thiel GJMW.

BMC Med Ethics. 2019 Mar 28;20(1):21. doi: 10.1186/s12910-019-0359-9.

17.

Lipid determinants of endocytosis and exocytosis in budding yeast.

Degreif D, Cucu B, Budin I, Thiel G, Bertl A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jul;1864(7):1005-1016. doi: 10.1016/j.bbalip.2019.03.007. Epub 2019 Mar 24.

PMID:
30917917
18.

Photolithographic Fabrication of Micro Apertures in Dry Film Polymer Sheets for Channel Recordings in Planar Lipid Bilayers.

Khoury ME, Winterstein T, Weber W, Stein V, Schlaak HF, Thiel G.

J Membr Biol. 2019 Jun;252(2-3):173-182. doi: 10.1007/s00232-019-00062-9. Epub 2019 Mar 12.

19.

Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.

Schönrock M, Thiel G, Laube B.

Commun Biol. 2019 Feb 22;2:75. doi: 10.1038/s42003-019-0320-y. eCollection 2019.

20.

Dihydrotestosterone activates AP-1 in LNCaP prostate cancer cells.

Thiel G, Welck J, Wissenbach U, Rössler OG.

Int J Biochem Cell Biol. 2019 May;110:9-20. doi: 10.1016/j.biocel.2019.02.005. Epub 2019 Feb 19.

PMID:
30794859
21.

Potential life-threatening complication of tonsillectomy: cervicofacial surgical emphysema.

Shoemaker K, Thompson CS, Sawant R, Thiel G.

BMJ Case Rep. 2019 Jan 20;12(1). pii: e228377. doi: 10.1136/bcr-2018-228377.

PMID:
30665932
22.

Minimal Clinically Important Difference and Substantial Clinical Benefit Values for the 12-Item International Hip Outcome Tool.

Martin RL, Kivlan BR, Christoforetti JJ, Wolff AB, Nho SJ, Salvo JP Jr, Ellis TJ, Van Thiel G, Matsuda DK, Carreira DS.

Arthroscopy. 2019 Feb;35(2):411-416. doi: 10.1016/j.arthro.2018.09.028. Epub 2019 Jan 4.

PMID:
30612776
23.
24.

The Impact of Depression on Patient Outcomes in Hip Arthroscopic Surgery.

Martin RL, Christoforetti JJ, McGovern R, Kivlan BR, Wolff AB, Nho SJ, Salvo JP Jr, Ellis TJ, Van Thiel G, Matsuda D, Carreira DS.

Orthop J Sports Med. 2018 Nov 15;6(11):2325967118806490. doi: 10.1177/2325967118806490. eCollection 2018 Nov.

25.

Developments in euthanasia practice in the Netherlands: Balancing professional responsibility and the patient's autonomy.

Kouwenhoven PSC, van Thiel GJMW, van der Heide A, Rietjens JAC, van Delden JJM.

Eur J Gen Pract. 2019 Jan;25(1):44-48. doi: 10.1080/13814788.2018.1517154. Epub 2018 Nov 1.

26.

A light-gated potassium channel for sustained neuronal inhibition.

Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A.

Nat Methods. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9. Epub 2018 Oct 30.

27.

Multimodal nocturnal seizure detection in a residential care setting: A long-term prospective trial.

Arends J, Thijs RD, Gutter T, Ungureanu C, Cluitmans P, Van Dijk J, van Andel J, Tan F, de Weerd A, Vledder B, Hofstra W, Lazeron R, van Thiel G, Roes KCB, Leijten F; the Dutch Tele-Epilepsy Consortium.

Neurology. 2018 Nov 20;91(21):e2010-e2019. doi: 10.1212/WNL.0000000000006545. Epub 2018 Oct 24.

28.

HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond.

Marini C, Porro A, Rastetter A, Dalle C, Rivolta I, Bauer D, Oegema R, Nava C, Parrini E, Mei D, Mercer C, Dhamija R, Chambers C, Coubes C, Thévenon J, Kuentz P, Julia S, Pasquier L, Dubourg C, Carré W, Rosati A, Melani F, Pisano T, Giardino M, Innes AM, Alembik Y, Scheidecker S, Santos M, Figueiroa S, Garrido C, Fusco C, Frattini D, Spagnoli C, Binda A, Granata T, Ragona F, Freri E, Franceschetti S, Canafoglia L, Castellotti B, Gellera C, Milanesi R, Mancardi MM, Clark DR, Kok F, Helbig KL, Ichikawa S, Sadler L, Neupauerová J, Laššuthova P, Šterbová K, Laridon A, Brilstra E, Koeleman B, Lemke JR, Zara F, Striano P, Soblet J, Smits G, Deconinck N, Barbuti A, DiFrancesco D, LeGuern E, Guerrini R, Santoro B, Hamacher K, Thiel G, Moroni A, DiFrancesco JC, Depienne C.

Brain. 2018 Nov 1;141(11):3160-3178. doi: 10.1093/brain/awy263.

29.

Ethics in clinical trial regulation: ethically relevant issues from EMA inspection reports.

Bernabe RDLC, van Thiel GJMW, Breekveldt NS, Gispen-de Wied CC, van Delden JJM.

Curr Med Res Opin. 2019 Apr;35(4):637-645. doi: 10.1080/03007995.2018.1528214. Epub 2018 Oct 29.

PMID:
30252539
30.

Further evidence for complex inheritance of holoprosencephaly: Lessons learned from pre- and postnatal diagnostic testing in Germany.

Hinreiner S, Wieczorek D, Mueller D, Roedl T, Thiel G, Grasshoff U, Chaoui R, Hehr U.

Am J Med Genet C Semin Med Genet. 2018 Jun;178(2):198-205. doi: 10.1002/ajmg.c.31625.

PMID:
30182445
31.

Genes for Membrane Transport Proteins: Not So Rare in Viruses.

Greiner T, Moroni A, Van Etten JL, Thiel G.

Viruses. 2018 Aug 26;10(9). pii: E456. doi: 10.3390/v10090456.

32.

Resveratrol stimulation induces interleukin-8 gene transcription via NF-κB.

Thiel G, Ulrich M, Mukaida N, Rössler OG.

Pharmacol Res. 2018 Aug;134:238-245. doi: 10.1016/j.phrs.2018.07.003. Epub 2018 Jul 6.

PMID:
30018026
33.

Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.

Rauh O, Hansen UP, Scheub DD, Thiel G, Schroeder I.

Sci Rep. 2018 Jul 10;8(1):10406. doi: 10.1038/s41598-018-28751-w.

34.

Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.

Gross C, Saponaro A, Santoro B, Moroni A, Thiel G, Hamacher K.

J Biol Chem. 2018 Aug 17;293(33):12908-12918. doi: 10.1074/jbc.RA118.002139. Epub 2018 Jun 23.

35.

A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A.

Elife. 2018 Jun 20;7. pii: e35753. doi: 10.7554/eLife.35753.

36.

Pragmatic clinical trials: ethical imperatives and opportunities.

Kalkman S, van Thiel GJMW, Grobbee DE, van Delden JJM.

Drug Discov Today. 2018 Dec;23(12):1919-1921. doi: 10.1016/j.drudis.2018.06.007. Epub 2018 Jun 12. No abstract available.

PMID:
29906514
37.

Treatment restrictions in patients with severe stroke are associated with an increased risk of death.

Geurts M, de Kort FA, de Kort PL, van Tuijl JH, van Thiel GJ, Kappelle LJ, van der Worp HB.

Eur Stroke J. 2017 Sep;2(3):244-249. doi: 10.1177/2396987317704546. Epub 2017 Apr 10.

38.

Minimum energy requirements for desalination of brackish groundwater in the United States with comparison to international datasets.

Ahdab YD, Thiel GP, Böhlke JK, Stanton J, Lienhard JH.

Water Res. 2018 Sep 15;141:387-404. doi: 10.1016/j.watres.2018.04.015. Epub 2018 Apr 12.

PMID:
29857319
39.

Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells.

Voos P, Fuck S, Weipert F, Babel L, Tandl D, Meckel T, Hehlgans S, Fournier C, Moroni A, Rödel F, Thiel G.

Front Immunol. 2018 Apr 30;9:922. doi: 10.3389/fimmu.2018.00922. eCollection 2018.

40.

Directional K+ channel insertion in a single phospholipid bilayer: Neutron reflectometry and electrophysiology in the joint exploration of a model membrane functional platform.

Rondelli V, Del Favero E, Brocca P, Fragneto G, Trapp M, Mauri L, Ciampa MG, Romani G, Braun CJ, Winterstein L, Schroeder I, Thiel G, Moroni A, Cantu' L.

Biochim Biophys Acta Gen Subj. 2018 Aug;1862(8):1742-1750. doi: 10.1016/j.bbagen.2018.05.007. Epub 2018 May 9.

41.

Sodium Hydroxide Production from Seawater Desalination Brine: Process Design and Energy Efficiency.

Du F, Warsinger DM, Urmi TI, Thiel GP, Kumar A, Lienhard V JH.

Environ Sci Technol. 2018 May 15;52(10):5949-5958. doi: 10.1021/acs.est.8b01195. Epub 2018 May 2.

PMID:
29669210
42.

Multimodal, automated detection of nocturnal motor seizures at home: Is a reliable seizure detector feasible?

van Andel J, Ungureanu C, Arends J, Tan F, Van Dijk J, Petkov G, Kalitzin S, Gutter T, de Weerd A, Vledder B, Thijs R, van Thiel G, Roes K, Leijten F.

Epilepsia Open. 2017 Sep 6;2(4):424-431. doi: 10.1002/epi4.12076. eCollection 2017 Dec.

43.

Resveratrol stimulates c-Fos gene transcription via activation of ERK1/2 involving multiple genetic elements.

Thiel G, Rössler OG.

Gene. 2018 Jun 5;658:70-75. doi: 10.1016/j.gene.2018.03.008. Epub 2018 Mar 5.

PMID:
29514046
44.

Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers.

Winterstein LM, Kukovetz K, Rauh O, Turman DL, Braun C, Moroni A, Schroeder I, Thiel G.

J Gen Physiol. 2018 Apr 2;150(4):637-646. doi: 10.1085/jgp.201711904. Epub 2018 Feb 27.

45.

Stimulation of TRPV1 channels activates the AP-1 transcription factor.

Backes TM, Rössler OG, Hui X, Grötzinger C, Lipp P, Thiel G.

Biochem Pharmacol. 2018 Apr;150:160-169. doi: 10.1016/j.bcp.2018.02.008. Epub 2018 Feb 13.

PMID:
29452097
46.

Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

Hemingway H, Asselbergs FW, Danesh J, Dobson R, Maniadakis N, Maggioni A, van Thiel GJM, Cronin M, Brobert G, Vardas P, Anker SD, Grobbee DE, Denaxas S; Innovative Medicines Initiative 2nd programme, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and industry partners including ESC.

Eur Heart J. 2018 Apr 21;39(16):1481-1495. doi: 10.1093/eurheartj/ehx487. Review.

47.

Regulation of Gene Transcription Following Stimulation of Transient Receptor Potential (TRP) Channels.

Thiel G, Lesch A, Rubil S, Backes TM, Rössler OG.

Int Rev Cell Mol Biol. 2018;335:167-189. doi: 10.1016/bs.ircmb.2017.07.010. Epub 2017 Aug 31. Review.

PMID:
29305012
48.

Sex-Dependent Differences in Preoperative, Radiographic, and Intraoperative Characteristics of Patients Undergoing Hip Arthroscopy: Results From the Multicenter Arthroscopic Study of the Hip Group.

Salvo JP, Nho SJ, Wolff AB, Christoforetti JJ, Van Thiel GS, Ellis TJ, Matsuda DK, Kivlan BR, Chaudhry ZS, Carreira DS.

Arthroscopy. 2018 Mar;34(3):844-852. doi: 10.1016/j.arthro.2017.09.044. Epub 2017 Dec 19.

PMID:
29273254
49.

Stimulation of B-Raf increases c-Jun and c-Fos expression and upregulates AP-1-regulated gene transcription in insulinoma cells.

Langfermann DS, Rössler OG, Thiel G.

Mol Cell Endocrinol. 2018 Sep 5;472:126-139. doi: 10.1016/j.mce.2017.12.003. Epub 2017 Dec 8.

PMID:
29225069
50.

Influence of genetic modifiers on sudden cardiac death cases.

Jenewein T, Neumann T, Erkapic D, Kuniss M, Verhoff MA, Thiel G, Kauferstein S.

Int J Legal Med. 2018 Mar;132(2):379-385. doi: 10.1007/s00414-017-1739-7. Epub 2017 Dec 6.

PMID:
29214556

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