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Items: 1 to 50 of 63

1.

MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer.

Wong CK, Gromisch C, Ozturk S, Papageorgis P, Abdolmaleky HM, Reinhard BM, Thiagalingam A, Thiagalingam S.

Cancer Biol Ther. 2019;20(8):1113-1120. doi: 10.1080/15384047.2019.1595285. Epub 2019 Mar 28.

PMID:
30922194
2.

Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis.

Kalli M, Mpekris F, Wong CK, Panagi M, Ozturk S, Thiagalingam S, Stylianopoulos T, Papageorgis P.

Front Oncol. 2019 Feb 5;9:32. doi: 10.3389/fonc.2019.00032. eCollection 2019.

3.

Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder.

Abdolmaleky HM, Gower AC, Wong CK, Cox JW, Zhang X, Thiagalingam A, Shafa R, Sivaraman V, Zhou JR, Thiagalingam S.

Am J Med Genet B Neuropsychiatr Genet. 2019 Mar;180(2):138-149. doi: 10.1002/ajmg.b.32691. Epub 2018 Nov 23.

PMID:
30468562
4.

Methamphetamine-induced psychosis is associated with DNA hypomethylation and increased expression of AKT1 and key dopaminergic genes.

Nohesara S, Ghadirivasfi M, Barati M, Ghasemzadeh MR, Narimani S, Mousavi-Behbahani Z, Joghataei M, Soleimani M, Taban M, Mehrabi S, Thiagalingam S, Abdolmaleky HM.

Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1180-1189. doi: 10.1002/ajmg.b.32506. Epub 2016 Oct 18.

PMID:
27753212
5.

SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis.

Ozturk S, Papageorgis P, Wong CK, Lambert AW, Abdolmaleky HM, Thiagalingam A, Cohen HT, Thiagalingam S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):638-43. doi: 10.1073/pnas.1514663113. Epub 2016 Jan 6.

6.

Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells.

Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S.

Mol Cancer Res. 2016 Jan;14(1):103-13. doi: 10.1158/1541-7786.MCR-15-0079. Epub 2015 Oct 27.

7.

Antipsychotic drugs attenuate aberrant DNA methylation of DTNBP1 (dysbindin) promoter in saliva and post-mortem brain of patients with schizophrenia and Psychotic bipolar disorder.

Abdolmaleky HM, Pajouhanfar S, Faghankhani M, Joghataei MT, Mostafavi A, Thiagalingam S.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):687-96. doi: 10.1002/ajmg.b.32361. Epub 2015 Aug 18.

PMID:
26285059
8.

Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.

Papageorgis P, Ozturk S, Lambert AW, Neophytou CM, Tzatsos A, Wong CK, Thiagalingam S, Constantinou AI.

Breast Cancer Res. 2015 Jul 25;17:98. doi: 10.1186/s13058-015-0607-y.

9.

An update on the epigenetics of psychotic diseases and autism.

Abdolmaleky HM, Zhou JR, Thiagalingam S.

Epigenomics. 2015;7(3):427-49. doi: 10.2217/epi.14.85. Review.

PMID:
26077430
10.

DNA hypermethylation of serotonin transporter gene promoter in drug naïve patients with schizophrenia.

Abdolmaleky HM, Nohesara S, Ghadirivasfi M, Lambert AW, Ahmadkhaniha H, Ozturk S, Wong CK, Shafa R, Mostafavi A, Thiagalingam S.

Schizophr Res. 2014 Feb;152(2-3):373-80. doi: 10.1016/j.schres.2013.12.007. Epub 2014 Jan 8.

PMID:
24411530
11.

Integrin signaling in mammary epithelial cells and breast cancer.

Lambert AW, Ozturk S, Thiagalingam S.

ISRN Oncol. 2012;2012:493283. doi: 10.5402/2012/493283. Epub 2012 Mar 1.

12.

Can the schizophrenia epigenome provide clues for the molecular basis of pathogenesis?

Abdolmaleky HM, Thiagalingam S.

Epigenomics. 2011 Dec;3(6):679-83. doi: 10.2217/epi.11.94. No abstract available.

PMID:
22126286
13.

DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder.

Nohesara S, Ghadirivasfi M, Mostafavi S, Eskandari MR, Ahmadkhaniha H, Thiagalingam S, Abdolmaleky HM.

J Psychiatr Res. 2011 Nov;45(11):1432-8. doi: 10.1016/j.jpsychires.2011.06.013. Epub 2011 Aug 5.

PMID:
21820670
14.

Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder.

Ghadirivasfi M, Nohesara S, Ahmadkhaniha HR, Eskandari MR, Mostafavi S, Thiagalingam S, Abdolmaleky HM.

Am J Med Genet B Neuropsychiatr Genet. 2011 Jul;156B(5):536-45. doi: 10.1002/ajmg.b.31192. Epub 2011 May 19.

PMID:
21598376
15.

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.

Abdolmaleky HM, Yaqubi S, Papageorgis P, Lambert AW, Ozturk S, Sivaraman V, Thiagalingam S.

Schizophr Res. 2011 Jul;129(2-3):183-90. doi: 10.1016/j.schres.2011.04.007. Epub 2011 May 7.

PMID:
21550210
16.

Smad4 inactivation promotes malignancy and drug resistance of colon cancer.

Papageorgis P, Cheng K, Ozturk S, Gong Y, Lambert AW, Abdolmaleky HM, Zhou JR, Thiagalingam S.

Cancer Res. 2011 Feb 1;71(3):998-1008. doi: 10.1158/0008-5472.CAN-09-3269. Epub 2011 Jan 18.

17.

Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky HM, Lenburg M, Thiagalingam S.

Cancer Res. 2010 Feb 1;70(3):968-78. doi: 10.1158/0008-5472.CAN-09-1872. Epub 2010 Jan 19.

18.

Corneal anomalies in newborn primary congenital glaucoma.

Thiagalingam S, Jakobiec FA, Chen T, Michaud N, Colby KA, Walton DS.

J Pediatr Ophthalmol Strabismus. 2009 Jul-Aug;46(4):241-4. doi: 10.3928/01913913-20090706-14. Epub 2009 Mar 20.

PMID:
19645407
19.

hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation.

Gao F, Ponte JF, Levy M, Papageorgis P, Cook NM, Ozturk S, Lambert AW, Thiagalingam A, Abdolmaleky HM, Sullivan BA, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):548-56. Epub 2009 Apr 22.

PMID:
19252416
20.

hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells.

Gao F, Ponte JF, Papageorgis P, Levy M, Ozturk S, Lambert AW, Pan H, Chinnappan D, Cheng KH, Thiagalingam A, Abdolmaleky HM, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):627-35. Epub 2009 Apr 22.

PMID:
19242126
21.

Boston keratoprosthesis in epithelial downgrowth.

Sa-Ngiampornpanit T, Thiagalingam S, Dohlman CH.

Digit J Ophthalmol. 2009 Jan 1;15(1):1-4. doi: 10.5693/djo.01.2009.001. eCollection 2009.

22.

Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics.

Abdolmaleky HM, Zhou JR, Thiagalingam S, Smith CL.

Pharmacogenomics. 2008 Dec;9(12):1809-23. doi: 10.2217/14622416.9.12.1809. Review.

PMID:
19072640
23.

Complications of cosmetic iris implants.

Thiagalingam S, Tarongoy P, Hamrah P, Lobo AM, Nagao K, Barsam C, Bellows R, Pineda R.

J Cataract Refract Surg. 2008 Jul;34(7):1222-4. doi: 10.1016/j.jcrs.2008.02.035.

PMID:
18571095
24.

Epigenetic alterations of the dopaminergic system in major psychiatric disorders.

Abdolmaleky HM, Smith CL, Zhou JR, Thiagalingam S.

Methods Mol Biol. 2008;448:187-212. doi: 10.1007/978-1-59745-205-2_9.

PMID:
18370235
25.

Endocrine mucin-producing sweat gland carcinoma of the eyelid.

Mehta S, Thiagalingam S, Zembowicz A, Hatton MP.

Ophthalmic Plast Reconstr Surg. 2008 Mar-Apr;24(2):164-5. doi: 10.1097/IOP.0b013e3181659c96.

PMID:
18356733
26.

Juvenile conjunctival nevus: clinicopathologic analysis of 33 cases.

Thiagalingam S, Johnson MM, Colby KA, Zembowicz A.

Am J Surg Pathol. 2008 Mar;32(3):399-406. doi: 10.1097/PAS.0b013e31815143f3.

PMID:
18300811
27.

Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression.

Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S.

Cancer Biol Ther. 2007 Oct;6(10):1638-43. Epub 2007 Aug 17.

PMID:
18245958
28.

What's your diagnosis? Acquired and progressive myelinated nerve fibers.

Thiagalingam S.

J Pediatr Ophthalmol Strabismus. 2007 Sep-Oct;44(5):274, 293. No abstract available.

PMID:
17913168
29.

Novel mutations in the KCNV2 gene in patients with cone dystrophy and a supernormal rod electroretinogram.

Thiagalingam S, McGee TL, Weleber RG, Sandberg MA, Trzupek KM, Berson EL, Dryja TP.

Ophthalmic Genet. 2007 Sep;28(3):135-42. Erratum in: Ophthalmic Genet. 2007 Dec;28(4):231.

PMID:
17896311
30.

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.

Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S.

Hum Mol Genet. 2006 Nov 1;15(21):3132-45. Epub 2006 Sep 19.

31.

A cascade of modules of a network defines cancer progression.

Thiagalingam S.

Cancer Res. 2006 Aug 1;66(15):7379-85.

32.

Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope.

Abdolmaleky HM, Thiagalingam S, Wilcox M.

Am J Pharmacogenomics. 2005;5(3):149-60. Review.

PMID:
15952869
33.

Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer.

Russo AL, Thiagalingam A, Pan H, Califano J, Cheng KH, Ponte JF, Chinnappan D, Nemani P, Sidransky D, Thiagalingam S.

Clin Cancer Res. 2005 Apr 1;11(7):2466-70.

34.

Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer.

Pan H, Califano J, Ponte JF, Russo AL, Cheng KH, Thiagalingam A, Nemani P, Sidransky D, Thiagalingam S.

Cancer Res. 2005 Mar 1;65(5):1664-9.

35.

Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report.

Abdolmaleky HM, Cheng KH, Russo A, Smith CL, Faraone SV, Wilcox M, Shafa R, Glatt SJ, Nguyen G, Ponte JF, Thiagalingam S, Tsuang MT.

Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134B(1):60-6.

PMID:
15717292
36.

Bilateral acute angle closure caused by supraciliary effusions associated with venlafaxine intake.

de Guzman MH, Thiagalingam S, Ong PY, Goldberg I.

Med J Aust. 2005 Feb 7;182(3):121-3. No abstract available. Erratum in: Med J Aust. 2005 Mar 21;182(6):312.

PMID:
15698358
37.

Orbital apex syndrome secondary to Pseudallescheria boydii fungal sinusitis in an immunocompetent patient.

Thiagalingam S, Fernando GT, Tan K, O'Donnell BA, Weeks K, Branley M.

Clin Exp Ophthalmol. 2004 Oct;32(5):545-7.

PMID:
15498073
38.

Neurofibromatosis type 1 and optic pathway gliomas: follow-up of 54 patients.

Thiagalingam S, Flaherty M, Billson F, North K.

Ophthalmology. 2004 Mar;111(3):568-77. Review.

PMID:
15019338
39.

Elucidation of epigenetic inactivation of SMAD8 in cancer using targeted expressed gene display.

Cheng KH, Ponte JF, Thiagalingam S.

Cancer Res. 2004 Mar 1;64(5):1639-46.

40.

Absence of change in choroidal nevi across 5 years in an older population.

Thiagalingam S, Wang JJ, Mitchell P.

Arch Ophthalmol. 2004 Jan;122(1):89-93.

PMID:
14718301
41.

Histone deacetylases: unique players in shaping the epigenetic histone code.

Thiagalingam S, Cheng KH, Lee HJ, Mineva N, Thiagalingam A, Ponte JF.

Ann N Y Acad Sci. 2003 Mar;983:84-100. Review.

PMID:
12724214
42.
43.

Five-year outcome of correctable visual impairment: the Blue Mountains Eye Study.

Foran S, Rose K, Wang JJ, Thiagalingam S, Mitchell P.

Clin Exp Ophthalmol. 2002 Jun;30(3):155-8.

PMID:
12010204
44.

Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence.

Thiagalingam S, Foy RL, Cheng KH, Lee HJ, Thiagalingam A, Ponte JF.

Curr Opin Oncol. 2002 Jan;14(1):65-72. Review. Erratum in: Curr Opin Oncol 2002 May;14(3):374.

PMID:
11790983
45.

Mechanisms underlying losses of heterozygosity in human colorectal cancers.

Thiagalingam S, Laken S, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B, Lengauer C.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2698-702. Epub 2001 Feb 13.

46.

Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.

Fink SP, Swinler SE, Lutterbaugh JD, Massagué J, Thiagalingam S, Kinzler KW, Vogelstein B, Willson JK, Markowitz S.

Cancer Res. 2001 Jan 1;61(1):256-60.

47.

Molecular detection of smad2/smad4 alterations in colorectal tumors.

Thiagalingam S.

Methods Mol Med. 2001;50:149-65. doi: 10.1385/1-59259-084-5:149.

PMID:
21318824
48.

Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

Grady WM, Myeroff LL, Swinler SE, Rajput A, Thiagalingam S, Lutterbaugh JD, Neumann A, Brattain MG, Chang J, Kim SJ, Kinzler KW, Vogelstein B, Willson JK, Markowitz S.

Cancer Res. 1999 Jan 15;59(2):320-4.

49.

14-3-3sigma is a p53-regulated inhibitor of G2/M progression.

Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B.

Mol Cell. 1997 Dec;1(1):3-11.

50.

Homeosis and polyposis: a tale from the mouse.

He TC, da Costa LT, Thiagalingam S.

Bioessays. 1997 Jul;19(7):551-5. Review.

PMID:
9230687

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