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Items: 14


siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.

Thi EP, Mire CE, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Cross RW, Kondratowicz AS, Fenton KA, MacLachlan I, Geisbert TW.

J Clin Invest. 2017 Dec 1;127(12):4437-4448. doi: 10.1172/JCI96185. Epub 2017 Nov 6.


Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.

Thi EP, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Fenton KA, Kondratowicz AS, MacLachlan I, Geisbert TW, Mire CE.

Nat Microbiol. 2016 Aug 22;1(10):16142. doi: 10.1038/nmicrobiol.2016.142.


Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates.

Mire CE, Geisbert JB, Agans KN, Thi EP, Lee AC, Fenton KA, Geisbert TW.

J Infect Dis. 2016 Oct 15;214(suppl 3):S367-S374. Epub 2016 Aug 28.


Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates.

Thi EP, Mire CE, Lee AC, Geisbert JB, Zhou JZ, Agans KN, Snead NM, Deer DJ, Barnard TR, Fenton KA, MacLachlan I, Geisbert TW.

Nature. 2015 May 21;521(7552):362-5. doi: 10.1038/nature14442. Epub 2015 Apr 22.


Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA.

Thi EP, Mire CE, Ursic-Bedoya R, Geisbert JB, Lee ACH, Agans KN, Robbins M, Deer DJ, Fenton KA, MacLachlan I, Geisbert TW.

Sci Transl Med. 2014 Aug 20;6(250):250ra116. doi: 10.1126/scitranslmed.3009706.


Antimicrobial activity, cytotoxicity and inflammatory response of novel plastics embedded with silver nanoparticles.

Martínez-Gutiérrez F, Guajardo-Pacheco JM, Noriega-Trevino ME, Thi EP, Reiner N, Orrantia E, Av-Gay Y, Ruiz F, Bach H.

Future Microbiol. 2013 Mar;8(3):403-11. doi: 10.2217/fmb.13.5.


Identification of the Mycobacterium tuberculosis protein PE-PGRS62 as a novel effector that functions to block phagosome maturation and inhibit iNOS expression.

Thi EP, Hong CJ, Sanghera G, Reiner NE.

Cell Microbiol. 2013 May;15(5):795-808. doi: 10.1111/cmi.12073. Epub 2012 Dec 19.


Class IA phosphatidylinositol 3-kinase p110α regulates phagosome maturation.

Thi EP, Lambertz U, Reiner NE.

PLoS One. 2012;7(8):e43668. doi: 10.1371/journal.pone.0043668. Epub 2012 Aug 22.


Phosphatidylinositol 3-kinases and their roles in phagosome maturation.

Thi EP, Reiner NE.

J Leukoc Biol. 2012 Sep;92(3):553-66. doi: 10.1189/jlb.0212053. Epub 2012 May 8. Review.


Sleeping with the enemy: how intracellular pathogens cope with a macrophage lifestyle.

Thi EP, Lambertz U, Reiner NE.

PLoS Pathog. 2012;8(3):e1002551. doi: 10.1371/journal.ppat.1002551. Epub 2012 Mar 22. No abstract available.


Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles.

Martínez-Gutierrez F, Thi EP, Silverman JM, de Oliveira CC, Svensson SL, Vanden Hoek A, Sánchez EM, Reiner NE, Gaynor EC, Pryzdial EL, Conway EM, Orrantia E, Ruiz F, Av-Gay Y, Bach H.

Nanomedicine. 2012 Apr;8(3):328-36. doi: 10.1016/j.nano.2011.06.014. Epub 2011 Jun 28.


Aedes Dronc: a novel ecdysone-inducible caspase in the yellow fever mosquito, Aedes aegypti.

Cooper DM, Thi EP, Chamberlain CM, Pio F, Lowenberger C.

Insect Mol Biol. 2007 Oct;16(5):563-72. Epub 2007 Aug 28.


Characterization of Aedes Dredd: a novel initiator caspase from the yellow fever mosquito, Aedes aegypti.

Cooper DM, Pio F, Thi EP, Theilmann D, Lowenberger C.

Insect Biochem Mol Biol. 2007 Jun;37(6):559-69. Epub 2007 Mar 14.


Extensive 3' modification of plant small RNAs is modulated by helper component-proteinase expression.

Ebhardt HA, Thi EP, Wang MB, Unrau PJ.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13398-403. Epub 2005 Sep 12.

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