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Items: 1 to 50 of 355

1.

Phase I metabolic profiling of the synthetic cannabinoids THJ-018 and THJ-2201 in human urine in comparison to human liver microsome and cytochrome P450 isoenzyme incubation.

Gaunitz F, Thomas A, Fietzke M, Franz F, Auwärter V, Thevis M, Mercer-Chalmers-Bender K.

Int J Legal Med. 2018 Dec 18. doi: 10.1007/s00414-018-1964-8. [Epub ahead of print]

PMID:
30564916
2.

Correction to: Post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in a case of combined drug intoxication.

Gaunitz F, Lehmann S, Thomas A, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K.

Int J Legal Med. 2018 Dec 5. doi: 10.1007/s00414-018-1976-4. [Epub ahead of print]

PMID:
30515589
3.

Annual banned-substance review: Analytical approaches in human sports drug testing.

Thevis M, Kuuranne T, Geyer H.

Drug Test Anal. 2019 Jan;11(1):8-26. doi: 10.1002/dta.2549. Epub 2019 Jan 6.

PMID:
30488582
4.

SARCOSYL-PAGE: Optimized Protocols for the Separation and Immunological Detection of PEGylated Proteins.

Reichel C, Gmeiner G, Reihlen P, Thevis M, Schänzer W.

Methods Mol Biol. 2019;1855:131-149. doi: 10.1007/978-1-4939-8793-1_14.

PMID:
30426415
5.

The 36th Manfred Donike workshop on doping analysis.

Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1633-1634. doi: 10.1002/dta.2536. Epub 2018 Nov 26. No abstract available.

PMID:
30394671
6.

Development of a mass spectrometry based detection method for the mitochondrion-derived peptide MOTS-c in plasma samples for doping control purposes.

Knoop A, Thomas A, Thevis M.

Rapid Commun Mass Spectrom. 2019 Feb 28;33(4):371-380. doi: 10.1002/rcm.8337.

PMID:
30394592
7.

Studies on the in vivo metabolism of the SARM YK11: Identification and characterization of metabolites potentially useful for doping controls.

Piper T, Dib J, Putz M, Fusshöller G, Pop V, Lagojda A, Kuehne D, Geyer H, Schänzer W, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1646-1656. doi: 10.1002/dta.2527. Epub 2018 Nov 18.

PMID:
30379415
8.

Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology: Impact on RBC deformability, oxidative stress, nitrite levels and nitric oxide synthase signalling pathway.

Nader E, Grau M, Fort R, Collins B, Cannas G, Gauthier A, Walpurgis K, Martin C, Bloch W, Poutrel S, Hot A, Renoux C, Thevis M, Joly P, Romana M, Guillot N, Connes P.

Nitric Oxide. 2018 Dec 1;81:28-35. doi: 10.1016/j.niox.2018.10.003. Epub 2018 Oct 19.

PMID:
30342855
9.

Analysis of insulin and insulin analogs from dried blood spots by means of liquid chromatography-high resolution mass spectrometry.

Thomas A, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1761-1768. doi: 10.1002/dta.2518. Epub 2018 Nov 8.

PMID:
30298989
10.

Combined detection of the ActRII-Fc fusion proteins Sotatercept (ActRIIA-Fc) and Luspatercept (modified ActRIIB-Fc) in serum by means of immunoaffinity purification, tryptic digestion, and LC-MS/MS.

Walpurgis K, Thomas A, Lange T, Reichel C, Geyer H, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1714-1721. doi: 10.1002/dta.2513. Epub 2018 Oct 30.

PMID:
30285318
11.

Effects of 3 Weeks of Oral Low-Dose Cobalt on Hemoglobin Mass and Aerobic Performance.

Hoffmeister T, Schwenke D, Krug O, Wachsmuth N, Geyer H, Thevis M, Byrnes WC, Schmidt WFJ.

Front Physiol. 2018 Sep 19;9:1289. doi: 10.3389/fphys.2018.01289. eCollection 2018.

12.

Recent improvements in sports drug testing concerning the initial testing for peptidic drugs (< 2 kDa) - sample preparation, mass spectrometric detection, and data review.

Görgens C, Guddat S, Thomas A, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1755-1760. doi: 10.1002/dta.2503. Epub 2018 Nov 8.

PMID:
30239151
13.

Case Study: Atypical δ13 C values of urinary norandrosterone.

Hülsemann F, Gougoulidis V, Schertel T, Fusshöller G, Flenker U, Piper T, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1728-1733. doi: 10.1002/dta.2498. Epub 2018 Oct 25.

PMID:
30230253
14.

Post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in a case of combined drug intoxication.

Gaunitz F, Lehmann S, Thomas A, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K.

Int J Legal Med. 2018 Nov;132(6):1645-1657. doi: 10.1007/s00414-018-1911-8. Epub 2018 Sep 15. Erratum in: Int J Legal Med. 2018 Dec 5;:.

PMID:
30219927
15.

Updated protocols for the detection of Sotatercept and Luspatercept in human serum.

Reichel C, Gmeiner G, Walpurgis K, Thevis M.

Drug Test Anal. 2018 Nov;10(11-12):1708-1713. doi: 10.1002/dta.2500. Epub 2018 Oct 1.

PMID:
30203930
16.

Response to letter to the editor: "Comments on Unambiguous identification and characterization of a long-term human metabolite of dehydrochloromethyltestosterone".

Forsdahl G, Geisendorfer T, Göschl L, Pfeffer S, Gärtner P, Thevis M, Gmeiner G.

Drug Test Anal. 2019 Jan;11(1):185. doi: 10.1002/dta.2486. Epub 2018 Sep 9. No abstract available.

PMID:
30133177
17.

Erythropoietic effects of low-dose cobalt application.

Hoffmeister T, Schwenke D, Wachsmuth N, Krug O, Thevis M, Byrnes WC, Schmidt WFJ.

Drug Test Anal. 2019 Feb;11(2):200-207. doi: 10.1002/dta.2478. Epub 2018 Sep 8.

PMID:
30110719
18.

Development and validation of a multidimensional gas chromatography/combustion/isotope ratio mass spectrometry-based test method for analyzing urinary steroids in doping controls.

Putz M, Piper T, Casilli A, Radler de Aquino Neto F, Pigozzo F, Thevis M.

Anal Chim Acta. 2018 Nov 7;1030:105-114. doi: 10.1016/j.aca.2018.05.016. Epub 2018 May 5.

PMID:
30032759
19.

Analysis of new growth promoting black market products.

Krug O, Thomas A, Malerød-Fjeld H, Dehnes Y, Laussmann T, Feldmann I, Sickmann A, Thevis M.

Growth Horm IGF Res. 2018 Aug;41:1-6. doi: 10.1016/j.ghir.2018.05.001. Epub 2018 May 19.

PMID:
29864719
20.

Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats.

Mori Y, Ko E, Furrer R, Qu LC, Wiber SC, Fantus IG, Thevis M, Medline A, Giacca A.

Endocr Connect. 2018 May;7(5):739-748. doi: 10.1530/EC-17-0358. Epub 2018 Apr 24.

21.

Unambiguous identification and characterization of a long-term human metabolite of dehydrochloromethyltestosterone.

Forsdahl G, Geisendorfer T, Göschl L, Pfeffer S, Gärtner P, Thevis M, Gmeiner G.

Drug Test Anal. 2018 Mar 23. doi: 10.1002/dta.2385. [Epub ahead of print]

PMID:
29570240
22.

Analytical challenges in sports drug testing.

Thevis M, Krug O, Geyer H, Walpurgis K, Baume N, Thomas A.

Anal Bioanal Chem. 2018 Mar;410(9):2275-2281. doi: 10.1007/s00216-018-0934-9. Epub 2018 Feb 14.

PMID:
29445832
23.

Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Hansson A, Knych H, Stanley S, Berndtson E, Jackson L, Bondesson U, Thevis M, Hedeland M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 1;1074-1075:91-98. doi: 10.1016/j.jchromb.2017.12.010. Epub 2017 Dec 7.

PMID:
29334634
24.

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control.

Garg N, Hansson A, Knych HK, Stanley SD, Thevis M, Bondesson U, Hedeland M, Globisch D.

Org Biomol Chem. 2018 Jan 31;16(5):698-702. doi: 10.1039/c7ob03030d.

PMID:
29319101
25.

Growth hormone isoform-differential mass spectrometry for doping control purposes.

Arsene C, Schulze D, Röthke A, Thevis M, Henrion A.

Drug Test Anal. 2018 Jun;10(6):938-946. doi: 10.1002/dta.2350. Epub 2018 Feb 26.

PMID:
29278456
26.

Mass spectrometric studies on selective androgen receptor modulators (SARMs) using electron ionization and electrospray ionization/collision-induced dissociation.

Thevis M, Volmer DA.

Eur J Mass Spectrom (Chichester). 2018 Feb;24(1):145-156. doi: 10.1177/1469066717731228. Epub 2017 Sep 13.

PMID:
29232975
27.

Detection of the Human Anti-ActRII Antibody Bimagrumab in Serum by Means of Affinity Purification, Tryptic Digestion, and LC-HRMS.

Walpurgis K, Thomas A, Dellanna F, Schänzer W, Thevis M.

Proteomics Clin Appl. 2018 May;12(3):e1700120. doi: 10.1002/prca.201700120. Epub 2018 Jan 19.

PMID:
29226558
28.

Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting.

Reichel C, Farmer L, Gmeiner G, Walpurgis K, Thevis M.

Drug Test Anal. 2018 Jun;10(6):927-937. doi: 10.1002/dta.2346. Epub 2017 Dec 27.

PMID:
29193906
29.

Annual banned-substance review: Analytical approaches in human sports drug testing.

Thevis M, Kuuranne T, Geyer H.

Drug Test Anal. 2018 Jan;10(1):9-27. doi: 10.1002/dta.2336. Epub 2017 Dec 18. Review.

PMID:
29149502
30.

The 35th Manfred Donike workshop on doping analysis.

Thevis M.

Drug Test Anal. 2017 Nov;9(11-12):1657. doi: 10.1002/dta.2328. Epub 2017 Nov 17. No abstract available.

PMID:
29065248
31.

Characterization of in vitro generated metabolites of selected peptides <2 kDa prohibited in sports.

Thomas A, Knoop A, Schänzer W, Thevis M.

Drug Test Anal. 2017 Nov;9(11-12):1799-1803. doi: 10.1002/dta.2306. Epub 2017 Nov 13.

PMID:
28941172
32.

Antibody-based strategies for the detection of Luspatercept (ACE-536) in human serum.

Reichel C, Gmeiner G, Thevis M.

Drug Test Anal. 2017 Nov;9(11-12):1721-1730. doi: 10.1002/dta.2302. Epub 2017 Nov 9.

PMID:
28929587
33.

Determination of 74 new psychoactive substances in serum using automated in-line solid-phase extraction-liquid chromatography-tandem mass spectrometry.

Lehmann S, Kieliba T, Beike J, Thevis M, Mercer-Chalmers-Bender K.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Oct 1;1064:124-138. doi: 10.1016/j.jchromb.2017.09.003. Epub 2017 Sep 7.

PMID:
28922649
34.

Applications of Isotope Ratio Mass Spectrometry in Sports Drug Testing Accounting for Isotope Fractionation in Analysis of Biological Samples.

Piper T, Thevis M.

Methods Enzymol. 2017;596:403-432. doi: 10.1016/bs.mie.2017.07.013. Epub 2017 Aug 24.

PMID:
28911778
35.

Potential of GHB phase-II-metabolites to complement current approaches in GHB post administration detection.

Piper T, Mehling LM, Spottke A, Heidbreder A, Young P, Madea B, Hess C, Schänzer W, Thevis M.

Forensic Sci Int. 2017 Oct;279:157-164. doi: 10.1016/j.forsciint.2017.08.023. Epub 2017 Aug 26.

PMID:
28869822
36.

Epiandrosterone sulfate prolongs the detectability of testosterone, 4-androstenedione, and dihydrotestosterone misuse by means of carbon isotope ratio mass spectrometry.

Piper T, Putz M, Schänzer W, Pop V, McLeod MD, Uduwela DR, Stevenson BJ, Thevis M.

Drug Test Anal. 2017 Nov;9(11-12):1695-1703. doi: 10.1002/dta.2291. Epub 2017 Oct 27.

PMID:
28836353
37.

Carbon isotope ratios of endogenous steroids in Belgian Blue and Holstein cattle: Method development, reference population studies and application to steroid misuse control.

Piper T, Putz M, Delahaut P, Thevis M.

Rapid Commun Mass Spectrom. 2017 Nov 15;31(21):1793-1802. doi: 10.1002/rcm.7964.

PMID:
28833805
38.

Nutrition Status of Young Elite Female German Football Players.

Braun H, von Andrian-Werburg J, Schänzer W, Thevis M.

Pediatr Exerc Sci. 2018 Feb 1;30(1):157-167. doi: 10.1123/pes.2017-0072. Epub 2017 Oct 20.

PMID:
28787242
39.

Immunoaffinity techniques coupled to mass spectrometry for the analysis of human peptide hormones: advances and applications.

Thomas A, Schänzer W, Thevis M.

Expert Rev Proteomics. 2017 Sep;14(9):799-807. doi: 10.1080/14789450.2017.1362338. Epub 2017 Aug 4. Review.

PMID:
28758805
40.

Determination of LongR3-IGF-I, R3-IGF-I, Des1-3 IGF-I and their metabolites in human plasma samples by means of LC-MS.

Thomas A, Walpurgis K, Delahaut P, Fichant E, Schänzer W, Thevis M.

Growth Horm IGF Res. 2017 Aug;35:33-39. doi: 10.1016/j.ghir.2017.06.002. Epub 2017 Jun 27.

PMID:
28668757
41.

Challenges in Modern Anti-Doping Analytical Science.

Ayotte C, Miller J, Thevis M.

Med Sport Sci. 2017;62:68-76. doi: 10.1159/000460701. Epub 2017 Jun 1.

PMID:
28571012
42.

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses.

Knych HK, Stanley SD, McKemie DS, Arthur RM, Bondesson U, Hedeland M, Thevis M, Kass PH.

Drug Test Anal. 2017 Sep;9(9):1392-1399. doi: 10.1002/dta.2214. Epub 2017 Aug 1.

PMID:
28513092
43.

Expanding analytical options in sports drug testing: Mass spectrometric detection of prohibited substances in exhaled breath.

Thevis M, Krug O, Geyer H, Schänzer W.

Rapid Commun Mass Spectrom. 2017 Aug 15;31(15):1290-1296. doi: 10.1002/rcm.7903.

44.

Mass spectrometric characterization of the selective androgen receptor modulator (SARM) YK-11 for doping control purposes.

Thevis M, Piper T, Dib J, Lagojda A, Kühne D, Packschies L, Geyer H, Schänzer W.

Rapid Commun Mass Spectrom. 2017 Jul 30;31(14):1175-1183. doi: 10.1002/rcm.7886.

PMID:
28440570
45.

lmplementation of the prolyl hydroxylase inhibitor Roxadustat (FG-4592) and its main metabolites into routine doping controls.

Eichner D, Van Wagoner RM, Brenner M, Chou J, Leigh S, Wright LR, Flippin LA, Martinelli M, Krug O, Schänzer W, Thevis M.

Drug Test Anal. 2017 Nov;9(11-12):1768-1778. doi: 10.1002/dta.2202. Epub 2017 May 31.

PMID:
28378453
46.

The atypical excretion profile of meldonium: Comparison of urinary detection windows after single- and multiple-dose application in healthy volunteers.

Görgens C, Guddat S, Bosse C, Geyer H, Pop V, Schänzer W, Thevis M.

J Pharm Biomed Anal. 2017 May 10;138:175-179. doi: 10.1016/j.jpba.2017.02.011. Epub 2017 Feb 6.

PMID:
28213178
47.

Qualitative and Semiquantitative Analysis of Doping Products Seized at the Swiss Border.

Weber C, Krug O, Kamber M, Thevis M.

Subst Use Misuse. 2017 May 12;52(6):742-753. doi: 10.1080/10826084.2016.1263665. Epub 2017 Feb 3.

PMID:
28156209
48.

Detection of SARMs in doping control analysis.

Thevis M, Schänzer W.

Mol Cell Endocrinol. 2018 Mar 15;464:34-45. doi: 10.1016/j.mce.2017.01.040. Epub 2017 Jan 27. Review.

PMID:
28137616
49.

Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry.

Hansson A, Thevis M, Cox H, Miller G, Eichner D, Bondesson U, Hedeland M.

J Pharm Biomed Anal. 2017 Feb 5;134:228-236. doi: 10.1016/j.jpba.2016.11.041. Epub 2016 Nov 27.

PMID:
27918992
50.

Annual banned-substance review: analytical approaches in human sports drug testing.

Thevis M, Kuuranne T, Geyer H, Schänzer W.

Drug Test Anal. 2017 Jan;9(1):6-29. doi: 10.1002/dta.2139. Review.

PMID:
27885819

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