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Items: 1 to 50 of 270

1.

Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche.

Binder M, Chmielarz P, Mckinnon PJ, Biggs LC, Thesleff I, Balic A.

Stem Cells. 2019 Sep;37(9):1238-1248. doi: 10.1002/stem.3042. Epub 2019 Jun 10.

PMID:
31145830
2.

From understanding tooth development to bioengineering of teeth.

Thesleff I.

Eur J Oral Sci. 2018 Oct;126 Suppl 1:67-71. doi: 10.1111/eos.12421. Review.

PMID:
30178557
3.

Mesenchymal Wnt/β-catenin signaling limits tooth number.

Järvinen E, Shimomura-Kuroki J, Balic A, Jussila M, Thesleff I.

Development. 2018 Feb 21;145(4). pii: dev158048. doi: 10.1242/dev.158048.

4.

Early epithelial signaling center governs tooth budding morphogenesis.

Ahtiainen L, Uski I, Thesleff I, Mikkola ML.

J Cell Biol. 2016 Sep 12;214(6):753-67. doi: 10.1083/jcb.201512074.

5.

Tissue Interactions Regulating Tooth Development and Renewal.

Balic A, Thesleff I.

Curr Top Dev Biol. 2015;115:157-86. doi: 10.1016/bs.ctdb.2015.07.006. Epub 2015 Oct 6. Review.

PMID:
26589925
6.

Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning.

Jussila M, Aalto AJ, Sanz Navarro M, Shirokova V, Balic A, Kallonen A, Ohyama T, Groves AK, Mikkola ML, Thesleff I.

Development. 2015 Nov 15;142(22):3954-63. doi: 10.1242/dev.124172. Epub 2015 Oct 8.

7.

Effect of Estrogen and Food Hardness on Metabolism and Turnover of Condylar Cartilage.

Orajärvi M, Thesleff I, Hartikainen H, Raustia A, Pirttiniemi P.

J Oral Facial Pain Headache. 2015 Summer;29(3):297-307. doi: 10.11607/ofph.1287.

PMID:
26244438
8.

Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10.

Yang Z, Balic A, Michon F, Juuri E, Thesleff I.

Stem Cells. 2015 May;33(5):1670-81. doi: 10.1002/stem.1972.

9.

Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor.

Heikinheimo K, Kurppa KJ, Laiho A, Peltonen S, Berdal A, Bouattour A, Ruhin B, Catón J, Thesleff I, Leivo I, Morgan PR.

J Dent Res. 2015 Jan;94(1):101-11. doi: 10.1177/0022034514556815. Epub 2014 Nov 14.

PMID:
25398365
10.

Glial origin of mesenchymal stem cells in a tooth model system.

Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, Clevers H, Thesleff I, Sharpe P, Ernfors P, Fried K, Adameyko I.

Nature. 2014 Sep 25;513(7519):551-4. doi: 10.1038/nature13536. Epub 2014 Jul 27.

PMID:
25079316
11.

Introduction to the ECR special odontology issue.

Thesleff I.

Exp Cell Res. 2014 Jul 15;325(2):57. doi: 10.1016/j.yexcr.2014.04.008. Epub 2014 Apr 18. No abstract available.

PMID:
24747302
12.

Directional cell migration, but not proliferation, drives hair placode morphogenesis.

Ahtiainen L, Lefebvre S, Lindfors PH, Renvoisé E, Shirokova V, Vartiainen MK, Thesleff I, Mikkola ML.

Dev Cell. 2014 Mar 10;28(5):588-602. doi: 10.1016/j.devcel.2014.02.003.

13.

Development of ectodermal organs.

Thesleff I, Mikkola ML.

Semin Cell Dev Biol. 2014 Jan-Feb;25-26:1-2. doi: 10.1016/j.semcdb.2014.02.002. Epub 2014 Feb 6. No abstract available.

PMID:
24508683
14.

Initiation of teeth from the dental lamina in the ferret.

Jussila M, Crespo Yanez X, Thesleff I.

Differentiation. 2014 Jan-Feb;87(1-2):32-43. doi: 10.1016/j.diff.2013.11.004. Epub 2014 Jan 6.

PMID:
24393477
15.

Current understanding of the process of tooth formation: transfer from the laboratory to the clinic.

Thesleff I.

Aust Dent J. 2014 Jun;59 Suppl 1:48-54. doi: 10.1111/adj.12102. Epub 2013 Nov 17.

16.

Expression of the stem cell marker, SOX2, in ameloblastoma and dental epithelium.

Juuri E, Isaksson S, Jussila M, Heikinheimo K, Thesleff I.

Eur J Oral Sci. 2013 Dec;121(6):509-16. doi: 10.1111/eos.12095. Epub 2013 Oct 23.

PMID:
24148099
17.

Sox2 marks epithelial competence to generate teeth in mammals and reptiles.

Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I.

Development. 2013 Apr;140(7):1424-32. doi: 10.1242/dev.089599. Epub 2013 Mar 5.

18.

Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes.

Shirokova V, Jussila M, Hytönen MK, Perälä N, Drögemüller C, Leeb T, Lohi H, Sainio K, Thesleff I, Mikkola ML.

Dev Dyn. 2013 Jun;242(6):593-603. doi: 10.1002/dvdy.23952. Epub 2013 Apr 9.

19.

Tooth shape formation and tooth renewal: evolving with the same signals.

Jernvall J, Thesleff I.

Development. 2012 Oct;139(19):3487-97. doi: 10.1242/dev.085084. Review.

20.

Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling.

Häärä O, Harjunmaa E, Lindfors PH, Huh SH, Fliniaux I, Åberg T, Jernvall J, Ornitz DM, Mikkola ML, Thesleff I.

Development. 2012 Sep;139(17):3189-99. doi: 10.1242/dev.079558. Epub 2012 Jul 25.

21.

Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors.

Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F.

Dev Cell. 2012 Aug 14;23(2):317-28. doi: 10.1016/j.devcel.2012.05.012. Epub 2012 Jul 19.

22.

Sostdc1 defines the size and number of skin appendage placodes.

Närhi K, Tummers M, Ahtiainen L, Itoh N, Thesleff I, Mikkola ML.

Dev Biol. 2012 Apr 15;364(2):149-61.

23.

Signaling networks regulating tooth organogenesis and regeneration, and the specification of dental mesenchymal and epithelial cell lineages.

Jussila M, Thesleff I.

Cold Spring Harb Perspect Biol. 2012 Apr 1;4(4):a008425. doi: 10.1101/cshperspect.a008425. Review.

24.

Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth.

Nieminen P, Morgan NV, Fenwick AL, Parmanen S, Veistinen L, Mikkola ML, van der Spek PJ, Giraud A, Judd L, Arte S, Brueton LA, Wall SA, Mathijssen IM, Maher ER, Wilkie AO, Kreiborg S, Thesleff I.

Am J Hum Genet. 2011 Jul 15;89(1):67-81. doi: 10.1016/j.ajhg.2011.05.024.

25.

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.

Häärä O, Fujimori S, Schmidt-Ullrich R, Hartmann C, Thesleff I, Mikkola ML.

Development. 2011 Jul;138(13):2681-91. doi: 10.1242/dev.057711.

26.

Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth.

Yoshida T, Miyoshi J, Takai Y, Thesleff I.

Dev Dyn. 2010 Oct;239(10):2558-69. doi: 10.1002/dvdy.22395.

27.

Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4.

Fujimori S, Novak H, Weissenböck M, Jussila M, Gonçalves A, Zeller R, Galloway J, Thesleff I, Hartmann C.

Dev Biol. 2010 Dec 1;348(1):97-106. doi: 10.1016/j.ydbio.2010.09.009. Epub 2010 Sep 27.

28.

Explant culture of embryonic craniofacial tissues: analyzing effects of signaling molecules on gene expression.

Närhi K, Thesleff I.

Methods Mol Biol. 2010;666:253-67. doi: 10.1007/978-1-60761-820-1_16.

PMID:
20717789
29.

Notch signalling is required for the survival of epithelial stem cells in the continuously growing mouse incisor.

Felszeghy S, Suomalainen M, Thesleff I.

Differentiation. 2010 Nov-Dec;80(4-5):241-8. doi: 10.1016/j.diff.2010.06.004. Epub 2010 Aug 6.

PMID:
20692087
30.

Splitting placodes: effects of bone morphogenetic protein and Activin on the patterning and identity of mouse incisors.

Munne PM, Felszeghy S, Jussila M, Suomalainen M, Thesleff I, Jernvall J.

Evol Dev. 2010 Jul-Aug;12(4):383-92. doi: 10.1111/j.1525-142X.2010.00425.x.

PMID:
20618434
31.

Tooth organogenesis and regeneration.

Thesleff I, Tummers M.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2009 Jan 31.

32.

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

Michon F, Tummers M, Kyyrönen M, Frilander MJ, Thesleff I.

Dev Biol. 2010 Apr 15;340(2):355-68. doi: 10.1016/j.ydbio.2010.01.019. Epub 2010 Jan 25.

33.

Treasure or artifact: a decade of p63 research speaks for itself.

Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI.

Cell Death Differ. 2010 Jan;17(1):180-3; author reply 184-6. doi: 10.1038/cdd.2009.157. No abstract available.

34.
35.

Novel Golgi protein, GoPro49, is a specific dental follicle marker.

Takatalo MS, Tummers M, Thesleff I, Rönnholm R.

J Dent Res. 2009 Jun;88(6):534-8. doi: 10.1177/0022034509338452.

PMID:
19587158
36.

The importance of signal pathway modulation in all aspects of tooth development.

Tummers M, Thesleff I.

J Exp Zool B Mol Dev Evol. 2009 Jun 15;312B(4):309-19. doi: 10.1002/jez.b.21280.

PMID:
19156667
37.

Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction.

Munne PM, Tummers M, Järvinen E, Thesleff I, Jernvall J.

Development. 2009 Feb;136(3):393-402. doi: 10.1242/dev.025064.

38.

The role of the dental lamina in mammalian tooth replacement.

Järvinen E, Tummers M, Thesleff I.

J Exp Zool B Mol Dev Evol. 2009 Jun 15;312B(4):281-91. doi: 10.1002/jez.b.21275.

PMID:
19137538
39.

Organ culture in the analysis of tissue interactions.

Thesleff I, Sahlberg C.

Methods Mol Biol. 2008;461:23-30. doi: 10.1007/978-1-60327-483-8_3. Review. No abstract available.

PMID:
19030788
40.

Runx1 is involved in the fusion of the primary and the secondary palatal shelves.

Charoenchaikorn K, Yokomizo T, Rice DP, Honjo T, Matsuzaki K, Shintaku Y, Imai Y, Wakamatsu A, Takahashi S, Ito Y, Takano-Yamamoto T, Thesleff I, Yamamoto M, Yamashiro T.

Dev Biol. 2009 Feb 15;326(2):392-402. doi: 10.1016/j.ydbio.2008.10.018. Epub 2008 Oct 29. Erratum in: Dev Biol. 2009 Nov 15;335(2):464.

41.

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development.

Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML.

Hum Mol Genet. 2008 Nov 1;17(21):3380-91. doi: 10.1093/hmg/ddn232. Epub 2008 Aug 9.

PMID:
18689798
42.

Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation.

Takatalo M, Järvinen E, Laitinen S, Thesleff I, Rönnholm R.

Dev Dyn. 2008 Aug;237(8):2243-55. doi: 10.1002/dvdy.21646.

43.

The taming of the shrew milk teeth.

Järvinen E, Välimäki K, Pummila M, Thesleff I, Jernvall J.

Evol Dev. 2008 Jul-Aug;10(4):477-86. doi: 10.1111/j.1525-142X.2008.00258.x.

PMID:
18638324
44.

Sumo-1 function is dispensable in normal mouse development.

Zhang FP, Mikkonen L, Toppari J, Palvimo JJ, Thesleff I, Jänne OA.

Mol Cell Biol. 2008 Sep;28(17):5381-90. doi: 10.1128/MCB.00651-08. Epub 2008 Jun 23.

45.

Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes.

Fliniaux I, Mikkola ML, Lefebvre S, Thesleff I.

Dev Biol. 2008 Aug 1;320(1):60-71. doi: 10.1016/j.ydbio.2008.04.023. Epub 2008 Apr 26.

47.

Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation.

Närhi K, Järvinen E, Birchmeier W, Taketo MM, Mikkola ML, Thesleff I.

Development. 2008 Mar;135(6):1019-28. doi: 10.1242/dev.016550. Epub 2008 Feb 6.

48.

Modulation of epithelial cell fate of the root in vitro.

Tummers M, Yamashiro T, Thesleff I.

J Dent Res. 2007 Nov;86(11):1063-7.

PMID:
17959897
49.

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning.

Kettunen P, Spencer-Dene B, Furmanek T, Kvinnsland IH, Dickson C, Thesleff I, Luukko K.

Mech Dev. 2007 Nov-Dec;124(11-12):868-83. Epub 2007 Sep 19.

50.

Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions.

Thesleff I, Järvinen E, Suomalainen M.

Novartis Found Symp. 2007;284:142-53; discussion 153-63. Review.

PMID:
17710852

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