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Items: 1 to 50 of 110

1.

Perspectives and experiences of adults who use AAC on making and keeping friends.

Therrien MCS.

Augment Altern Commun. 2019 Apr 29:1-12. doi: 10.1080/07434618.2019.1599065. [Epub ahead of print]

PMID:
31030567
2.

Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.

Ambalavanan A, Chaumette B, Zhou S, Xie P, He Q, Spiegelman D, Dionne-Laporte A, Bourassa CV, Therrien M, Rochefort D, Xiong L, Dion PA, Joober R, Rapoport JL, Girard SL, Rouleau GA.

Am J Med Genet B Neuropsychiatr Genet. 2018 Oct 30. doi: 10.1002/ajmg.b.32683. [Epub ahead of print]

PMID:
30378261
3.

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.

Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB.

Nat Commun. 2018 Oct 22;9(1):4385. doi: 10.1038/s41467-018-06854-2.

4.

Implementation project of the non-pneumatic anti-shock garment and m-communication to enhance maternal health care in rural Tanzania.

Mbaruku G, Therrien MS, Tillya R, Mbuyita S, Mtema Z, Kinyonge I, Godfrey R, Temu S, Miller S.

Reprod Health. 2018 Oct 19;15(1):177. doi: 10.1186/s12978-018-0613-5.

5.

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect.

Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, Kerr B, Linardic CM, McMahon M, Oberlander B, Perlstein E, Ratner N, Rogers L, Schenck A, Shankar S, Shvartsman S, Stevenson DA, Stites EC, Stork PJS, Sun C, Therrien M, Ullian EM, Widemann BC, Yeh E, Zampino G, Zenker M, Timmer W, McCormick F.

Am J Med Genet A. 2018 Dec;176(12):2924-2929. doi: 10.1002/ajmg.a.40632. Epub 2018 Oct 10.

PMID:
30302932
6.

Whole Grain Muffin Acceptance by Young Adults.

Mellette T, Yerxa K, Therrien M, Camire ME.

Foods. 2018 Jun 13;7(6). pii: E91. doi: 10.3390/foods7060091.

7.

MEK drives BRAF activation through allosteric control of KSR proteins.

Lavoie H, Sahmi M, Maisonneuve P, Marullo SA, Thevakumaran N, Jin T, Kurinov I, Sicheri F, Therrien M.

Nature. 2018 Feb 22;554(7693):549-553. doi: 10.1038/nature25478. Epub 2018 Feb 12.

8.

Promoting Peer Interaction for Preschool Children With Complex Communication Needs and Autism Spectrum Disorder.

Therrien MCS, Light JC.

Am J Speech Lang Pathol. 2018 Feb 6;27(1):207-221. doi: 10.1044/2017_AJSLP-17-0104.

PMID:
29383382
9.

RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition.

Jin T, Lavoie H, Sahmi M, David M, Hilt C, Hammell A, Therrien M.

Nat Commun. 2017 Oct 31;8(1):1211. doi: 10.1038/s41467-017-01274-0.

10.

Resolving CNS mRNA Heterogeneity: Examining mRNA Alternative Polyadenylation at a Cell-Type-Specific Level.

Therrien M, Heiman M.

Neuron. 2017 Sep 13;95(6):1232-1233. doi: 10.1016/j.neuron.2017.08.045.

11.

Bridging complexity theory and resilience to develop surge capacity in health systems.

Therrien MC, Normandin JM, Denis JL.

J Health Organ Manag. 2017 Mar 20;31(1):96-109. doi: 10.1108/JHOM-04-2016-0067.

PMID:
28260411
12.

Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK.

Kubiniok P, Lavoie H, Therrien M, Thibault P.

Mol Cell Proteomics. 2017 Apr;16(4):663-679. doi: 10.1074/mcp.M116.065128. Epub 2017 Feb 10.

13.

How Genetics Has Helped Piece Together the MAPK Signaling Pathway.

Ashton-Beaucage D, Therrien M.

Methods Mol Biol. 2017;1487:1-21. Review.

PMID:
27924555
14.

Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila.

Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien M.

Dev Biol. 2017 Jan 1;421(1):16-26. doi: 10.1016/j.ydbio.2016.11.003. Epub 2016 Nov 10.

15.

Inhibition of RAS function through targeting an allosteric regulatory site.

Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP.

Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7.

16.

Insufficient developmental excitatory neuronal activity fails to foster establishment of normal levels of inhibitory neuronal activity.

Therrien M, Vohnoutka R, Boumil E, Guaraldi M, Lee S, Shea TB.

Int J Dev Neurosci. 2016 Dec;55:66-71. doi: 10.1016/j.ijdevneu.2016.09.009. Epub 2016 Sep 26.

PMID:
27686511
17.

Validation of sleep-2-Peak: A smartphone application that can detect fatigue-related changes in reaction times during sleep deprivation.

Brunet JF, Dagenais D, Therrien M, Gartenberg D, Forest G.

Behav Res Methods. 2017 Aug;49(4):1460-1469. doi: 10.3758/s13428-016-0802-5.

PMID:
27631990
18.

The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila.

Ashton-Beaucage D, Lemieux C, Udell CM, Sahmi M, Rochette S, Therrien M.

PLoS Biol. 2016 Aug 23;14(8):e1002539. doi: 10.1371/journal.pbio.1002539. eCollection 2016 Aug.

19.

Using the iPad to facilitate interaction between preschool children who use AAC and their peers.

Therrien MC, Light J.

Augment Altern Commun. 2016 Sep;32(3):163-74. doi: 10.1080/07434618.2016.1205133. Epub 2016 Jul 14.

PMID:
27414808
20.

FET proteins regulate lifespan and neuronal integrity.

Therrien M, Rouleau GA, Dion PA, Parker JA.

Sci Rep. 2016 Apr 27;6:25159. doi: 10.1038/srep25159.

21.

ALS: Recent Developments from Genetics Studies.

Therrien M, Dion PA, Rouleau GA.

Curr Neurol Neurosci Rep. 2016 Jun;16(6):59. doi: 10.1007/s11910-016-0658-1. Review.

PMID:
27113253
22.

Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).

Aaron C, Beaudry G, Parker JA, Therrien M.

J Agric Food Chem. 2016 May 4;64(17):3338-44. doi: 10.1021/acs.jafc.5b05432. Epub 2016 Apr 20.

PMID:
27071850
23.

Systematic Review of the Effects of Interventions to Promote Peer Interactions for Children who use Aided AAC.

Therrien MC, Light J, Pope L.

Augment Altern Commun. 2016 Jun;32(2):81-93. doi: 10.3109/07434618.2016.1146331. Epub 2016 Feb 23. Review.

PMID:
26903484
24.

Neural Activity Associated with Visual Search for Line Drawings on AAC Displays: An Exploration of the Use of fMRI.

Wilkinson KM, Dennis NA, Webb CE, Therrien M, Stradtman M, Farmer J, Leach R, Warrenfeltz M, Zeuner C.

Augment Altern Commun. 2015;31(4):310-24. doi: 10.3109/07434618.2015.1100215.

PMID:
26517757
25.

Additive Impairment of Synaptic Signaling in Cultured Cortical Neurons by Exogenously-Applied Oligomerized Amyloid-β and Airborne Nanoparticles Generated during Photocopying.

Lee S, Sohal IS, Therrien MA, Pal AK, Bello D, Shea TB.

J Alzheimers Dis. 2015;47(1):49-54. doi: 10.3233/JAD-150099.

PMID:
26402753
26.

Regulation of RAF protein kinases in ERK signalling.

Lavoie H, Therrien M.

Nat Rev Mol Cell Biol. 2015 May;16(5):281-98. doi: 10.1038/nrm3979. Review.

PMID:
25907612
27.

A Review of Dietary Intake Studies in Maintenance Dialysis Patients.

Therrien M, Byham-Gray L, Beto J.

J Ren Nutr. 2015 Jul;25(4):329-38. doi: 10.1053/j.jrn.2014.11.001. Epub 2015 Jan 13. Review.

PMID:
25592493
28.

Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.

Thevakumaran N, Lavoie H, Critton DA, Tebben A, Marinier A, Sicheri F, Therrien M.

Nat Struct Mol Biol. 2015 Jan;22(1):37-43. doi: 10.1038/nsmb.2924. Epub 2014 Dec 1.

PMID:
25437913
29.

Deciphering genetic interactions between ALS genes using C. elegans.

Therrien M, Parker JA.

Worm. 2014 May 8;3:e29047. doi: 10.4161/worm.29047. eCollection 2014.

30.

Dimerization-induced allostery in protein kinase regulation.

Lavoie H, Li JJ, Thevakumaran N, Therrien M, Sicheri F.

Trends Biochem Sci. 2014 Oct;39(10):475-86. doi: 10.1016/j.tibs.2014.08.004. Epub 2014 Sep 11. Review.

PMID:
25220378
31.

Synaptic signal streams generated by ex vivo neuronal networks contain non-random, complex patterns.

Lee S, Zemianek JM, Shultz A, Vo A, Maron BY, Therrien M, Courtright C, Guaraldi M, Yanco HA, Shea TB.

Int J Dev Neurosci. 2014 Nov;38:184-94. doi: 10.1016/j.ijdevneu.2014.08.008. Epub 2014 Aug 27.

PMID:
25172170
32.

Isolated hemopericardium associated with rivaroxaban: first case report.

Shivamurthy P, Brar N, Therrien ML.

Pharmacotherapy. 2014 Sep;34(9):e169-72. doi: 10.1002/phar.1474. Epub 2014 Jul 30.

PMID:
25074401
33.

Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1.

Baril C, Lefrançois M, Sahmi M, Knævelsrud H, Therrien M.

Genetics. 2014 Aug;197(4):1237-50. doi: 10.1534/genetics.114.166272. Epub 2014 Jun 3.

34.

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans.

Therrien M, Parker JA.

Front Genet. 2014 Apr 17;5:85. doi: 10.3389/fgene.2014.00085. eCollection 2014. Review.

35.

Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.

Mashtalir N, Daou S, Barbour H, Sen NN, Gagnon J, Hammond-Martel I, Dar HH, Therrien M, Affar el B.

Mol Cell. 2014 May 8;54(3):392-406. doi: 10.1016/j.molcel.2014.03.002. Epub 2014 Apr 3.

36.

A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila.

Ashton-Beaucage D, Udell CM, Gendron P, Sahmi M, Lefrançois M, Baril C, Guenier AS, Duchaine J, Lamarre D, Lemieux S, Therrien M.

PLoS Biol. 2014 Mar 18;12(3):e1001809. doi: 10.1371/journal.pbio.1001809. eCollection 2014 Mar.

37.

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans.

Therrien M, Rouleau GA, Dion PA, Parker JA.

PLoS One. 2013 Dec 12;8(12):e83450. doi: 10.1371/journal.pone.0083450. eCollection 2013.

38.

Comparison of dietary intake among women on maintenance dialysis to a Women's Health Initiative cohort: results from the NKF-CRN Second National Research Question Collaborative Study.

Therrien M, Byham-Gray L, Denmark R, Beto J.

J Ren Nutr. 2014 Mar;24(2):72-80. doi: 10.1053/j.jrn.2013.09.005. Epub 2013 Nov 27.

PMID:
24290672
39.

Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.

Lavoie H, Thevakumaran N, Gavory G, Li JJ, Padeganeh A, Guiral S, Duchaine J, Mao DY, Bouvier M, Sicheri F, Therrien M.

Nat Chem Biol. 2013 Jul;9(7):428-36. doi: 10.1038/nchembio.1257. Epub 2013 May 19.

40.

Effects of band-pass spatial frequency filtering of face and object images on the amplitude of N170.

Collin CA, Therrien ME, Campbell KB, Hamm JP.

Perception. 2012;41(6):717-32.

PMID:
23094460
41.

ÉquiNanos: innovative team for nanoparticle risk management.

Nadeau S, Bouchard M, Debia M, DeMarcellis-Warin N, Hallé S, Songmene V, Therrien MC, Wilkinson K, Ateme-Nguema B, Dufour G, Dufresne A, Fatisson J, Haddad S, Hadioui M, Kouam J, Morency F, Tardif R, Viens M, Weichenthal S, Viau C, Camus M.

Nanomedicine. 2013 Jan;9(1):22-4. doi: 10.1016/j.nano.2012.08.003. Epub 2012 Sep 6.

PMID:
22960193
42.

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

Vaccaro A, Patten SA, Ciura S, Maios C, Therrien M, Drapeau P, Kabashi E, Parker JA.

PLoS One. 2012;7(7):e42117. doi: 10.1371/journal.pone.0042117. Epub 2012 Jul 27.

43.

Elementary school-located influenza vaccine programs: key stakeholder experiences from initiation to continuation.

Williams V, Rousculp MD, Price M, Coles T, Therrien M, Griffin J, Hollis K, Toback S.

J Sch Nurs. 2012 Aug;28(4):256-67. doi: 10.1177/1059840512438776. Epub 2012 Mar 16.

PMID:
22427316
44.

Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models.

Stochmanski SJ, Therrien M, Laganière J, Rochefort D, Laurent S, Karemera L, Gaudet R, Vyboh K, Van Meyel DJ, Di Cristo G, Dion PA, Gaspar C, Rouleau GA.

Hum Mol Genet. 2012 May 15;21(10):2211-8. doi: 10.1093/hmg/dds036. Epub 2012 Feb 14.

PMID:
22337953
45.

Care coordination for children with special health care needs and roles for physical therapists.

McSpadden C, Therrien M, McEwen IR.

Pediatr Phys Ther. 2012 Spring;24(1):70-7. doi: 10.1097/PEP.0b013e31823e0686.

PMID:
22207474
46.

Cancer: A drug-resistant duo.

Lavoie H, Therrien M.

Nature. 2011 Dec 14;480(7377):329-30. doi: 10.1038/480329a. No abstract available.

PMID:
22170679
47.

Center of Mass Compensation during Gait in Hip Arthroplasty Patients: Comparison between Large Diameter Head Total Hip Arthroplasty and Hip Resurfacing.

Bouffard V, Nantel J, Therrien M, Vendittoli PA, Lavigne M, Prince F.

Rehabil Res Pract. 2011;2011:586412. doi: 10.1155/2011/586412. Epub 2011 Sep 18.

48.

The exon junction complex: a splicing factor for long intron containing transcripts?

Ashton-Beaucage D, Therrien M.

Fly (Austin). 2011 Jul-Sep;5(3):224-33. Epub 2011 Jul 1.

PMID:
21478676
49.

[The greater RTK/RAS/ERK signalling pathway: how genetics has helped piece together a signalling network].

Ashton-Beaucage D, Therrien M.

Med Sci (Paris). 2010 Dec;26(12):1067-73. doi: 10.1051/medsci/201026121067. Review. French.

50.

A comprehensive map of the mTOR signaling network.

Caron E, Ghosh S, Matsuoka Y, Ashton-Beaucage D, Therrien M, Lemieux S, Perreault C, Roux PP, Kitano H.

Mol Syst Biol. 2010 Dec 21;6:453. doi: 10.1038/msb.2010.108. Review.

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