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Items: 1 to 50 of 399

1.

IL-33 stimulates human mast cell release of CCL5 and CCL2 via MAPK and NF-κB, inhibited by methoxyluteolin.

Bawazeer MA, Theoharides TC.

Eur J Pharmacol. 2019 Oct 26:172760. doi: 10.1016/j.ejphar.2019.172760. [Epub ahead of print]

2.

IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin.

Tsilioni I, Patel AB, Pantazopoulos H, Berretta S, Conti P, Leeman SE, Theoharides TC.

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21659-21665. doi: 10.1073/pnas.1906817116. Epub 2019 Oct 7.

PMID:
31591201
3.

Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder.

Almehmadi KA, Tsilioni I, Theoharides TC.

Autism Res. 2019 Sep 10. doi: 10.1002/aur.2205. [Epub ahead of print]

PMID:
31502418
4.

Mast Cells, Neuroinflammation and Pain in Fibromyalgia Syndrome.

Theoharides TC, Tsilioni I, Bawazeer M.

Front Cell Neurosci. 2019 Aug 2;13:353. doi: 10.3389/fncel.2019.00353. eCollection 2019. Review.

5.

Nasal cytology with emphasis on mast cells can improve the diagnosis and treatment of chronic rhinosinusitis.

Ren HL, Li JD, Yue FS, Sun JL, Rebeiz EE, Theoharides TC.

Chin Med J (Engl). 2019 Sep 20;132(18):2237-2241. doi: 10.1097/CM9.0000000000000387.

PMID:
31425355
6.

Mast Cells May Regulate The Anti-Inflammatory Activity of IL-37.

Theoharides TC, Tsilioni I, Conti P.

Int J Mol Sci. 2019 Jul 29;20(15). pii: E3701. doi: 10.3390/ijms20153701.

7.

Mast Cells, Stress, Fear and Autism Spectrum Disorder.

Theoharides TC, Kavalioti M, Tsilioni I.

Int J Mol Sci. 2019 Jul 24;20(15). pii: E3611. doi: 10.3390/ijms20153611. Review.

8.

Effects of an Extract of Salmon Milt on Symptoms and Serum TNF and Substance P in Patients With Fibromyalgia Syndrome.

Tsilioni I, Pipis H, Freitag MSC, Izquierdo MDC, Freitag K, Theoharides TC.

Clin Ther. 2019 Aug;41(8):1564-1574.e2. doi: 10.1016/j.clinthera.2019.05.019. Epub 2019 Jul 11.

PMID:
31303280
9.

Effect of stress on learning and motivation-relevance to autism spectrum disorder.

Theoharides TC, Kavalioti M.

Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419856760. doi: 10.1177/2058738419856760.

10.

The mast cell - neurofibromatosis connection.

Antonopoulos D, Tsilioni I, Balatsos NAA, Gourgoulianis KI, Theoharides TC.

J Biol Regul Homeost Agents. 2019 May-Jun,;33(3):657-659.

PMID:
31184097
11.

Intimate Contact Could Be Dangerous for Your Health.

Kounis NG, Ren HL, Kavalioti M, Koniari I, Theoharides TC.

Clin Ther. 2019 Jun;41(6):1222-1226. doi: 10.1016/j.clinthera.2019.04.010. Epub 2019 May 7. Review.

PMID:
31076202
12.

In Search of Effective Treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Theoharides TC.

Clin Ther. 2019 May;41(5):796-797. doi: 10.1016/j.clinthera.2019.04.011. Epub 2019 Apr 25. No abstract available.

PMID:
31030992
13.

IgE and macrophages for cancer rescue?

Conti P, Theoharides TC.

EBioMedicine. 2019 May;43:7-8. doi: 10.1016/j.ebiom.2019.04.024. Epub 2019 Apr 18. No abstract available.

14.

A Timely Multidisciplinary Update on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Theoharides TC.

Clin Ther. 2019 Apr;41(4):610-611. doi: 10.1016/j.clinthera.2019.03.004. Epub 2019 Mar 30. No abstract available.

PMID:
30940402
15.

Recent advances in our understanding of mast cell activation - or should it be mast cell mediator disorders?

Theoharides TC, Tsilioni I, Ren H.

Expert Rev Clin Immunol. 2019 Jun;15(6):639-656. doi: 10.1080/1744666X.2019.1596800. Epub 2019 Apr 22.

PMID:
30884251
16.

Stress, inflammation and natural treatments.

Theoharides TC, Kavalioti M.

J Biol Regul Homeost Agents. 2018 Nov-Dec;32(6):1345-1347.

PMID:
30574737
17.

Chondroitin sulfate inhibits secretion of TNF and CXCL8 from human mast cells stimulated by IL-33.

Gross AR, Theoharides TC.

Biofactors. 2019 Jan;45(1):49-61. doi: 10.1002/biof.1464. Epub 2018 Dec 6.

PMID:
30521103
18.

Tetramethoxyluteolin for the Treatment of Neurodegenerative Diseases.

Theoharides TC, Tsilioni I.

Curr Top Med Chem. 2018;18(21):1872-1882. doi: 10.2174/1568026617666181119154247. Review.

PMID:
30451113
19.

Effect of IL-33 on de novo synthesized mediators from human mast cells.

Theoharides TC, Leeman SE.

J Allergy Clin Immunol. 2019 Jan;143(1):451. doi: 10.1016/j.jaci.2018.09.014. Epub 2018 Nov 1. No abstract available.

PMID:
30390921
20.

Mitochondrial dysfunction in affected skin and increased mitochondrial DNA in serum from patients with psoriasis.

Therianou A, Vasiadi M, Delivanis DA, Petrakopoulou T, Katsarou-Katsari A, Antoniou C, Stratigos A, Tsilioni I, Katsambas A, Rigopoulos D, Theoharides TC.

Exp Dermatol. 2019 Jan;28(1):72-75. doi: 10.1111/exd.13831.

PMID:
30390357
21.

Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin.

Taracanova A, Tsilioni I, Conti P, Norwitz ER, Leeman SE, Theoharides TC.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9381-E9390. doi: 10.1073/pnas.1810133115. Epub 2018 Sep 19.

22.
23.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-Metabolic Disease or Disturbed Homeostasis due to Focal Inflammation in the Hypothalamus?

Hatziagelaki E, Adamaki M, Tsilioni I, Dimitriadis G, Theoharides TC.

J Pharmacol Exp Ther. 2018 Oct;367(1):155-167. doi: 10.1124/jpet.118.250845. Epub 2018 Aug 3. Review.

PMID:
30076265
24.

Critical role of inflammatory mast cell in fibrosis: Potential therapeutic effect of IL-37.

Conti P, Caraffa A, Mastrangelo F, Tettamanti L, Ronconi G, Frydas I, Kritas SK, Theoharides TC.

Cell Prolif. 2018 Oct;51(5):e12475. doi: 10.1111/cpr.12475. Epub 2018 Jul 30. Review.

PMID:
30062695
25.

Mast cells participate in allograft rejection: can IL-37 play an inhibitory role?

Conti P, Caraffa A, Ronconi G, Kritas SK, Mastrangelo F, Tettamanti L, Frydas I, Theoharides TC.

Inflamm Res. 2018 Sep;67(9):747-755. doi: 10.1007/s00011-018-1166-3. Epub 2018 Jun 30. Review.

PMID:
29961151
26.

Time to look past TNF and thalidomide for cachexia - could mast cells and flavonoids be the answer?

King L, Tsilioni I, Theoharides TC.

J Biol Regul Homeost Agents. 2018 May-Jun;32(3):443-447.

PMID:
29921368
27.

Impact of mast cells in depression disorder: inhibitory effect of IL-37 (new frontiers).

Conti P, Caraffa A, Ronconi G, Conti CM, Kritas SK, Mastrangelo F, Tettamanti L, Theoharides TC.

Immunol Res. 2018 Jun;66(3):323-331. doi: 10.1007/s12026-018-9004-9. Review.

PMID:
29907890
28.

Activated Mast Cells Mediate Low-Grade Inflammation in Type 2 Diabetes: Interleukin-37 Could Be Beneficial.

Conti P, Ronconi G, Kritas SK, Caraffa A, Theoharides TC.

Can J Diabetes. 2018 Oct;42(5):568-573. doi: 10.1016/j.jcjd.2018.01.008. Epub 2018 Jan 31. Review.

PMID:
29885882
29.

Effects of Mycotoxins on Neuropsychiatric Symptoms and Immune Processes.

Ratnaseelan AM, Tsilioni I, Theoharides TC.

Clin Ther. 2018 Jun;40(6):903-917. doi: 10.1016/j.clinthera.2018.05.004. Epub 2018 Jun 5. Review.

PMID:
29880330
30.

Mold and Immunity.

Theoharides TC.

Clin Ther. 2018 Jun;40(6):882-884. doi: 10.1016/j.clinthera.2018.05.005. Epub 2018 May 30. No abstract available.

PMID:
29859636
31.

Interleukin 33 and interleukin 4 regulate interleukin 31 gene expression and secretion from human laboratory of allergic diseases 2 mast cells stimulated by substance P and/or immunoglobulin E.

Petra AI, Tsilioni I, Taracanova A, Katsarou-Katsari A, Theoharides TC.

Allergy Asthma Proc. 2018 Mar 1;39(2):153-160. doi: 10.2500/aap.2018.38.4105.

32.

Reply to Fattori et al.: Action of SP and IL-33 on mast cells.

Theoharides TC, Taracanova A, Tsilioni I, Conti P, Leeman SE.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10036. doi: 10.1073/pnas.1716233114. Epub 2017 Nov 6. No abstract available.

33.

TNF stimulates IL-6, CXCL8 and VEGF secretion from human keratinocytes via activation of mTOR, inhibited by tetramethoxyluteolin.

Patel AB, Tsilioni I, Weng Z, Theoharides TC.

Exp Dermatol. 2018 Feb;27(2):135-143. doi: 10.1111/exd.13461. Epub 2018 Jan 3.

PMID:
29105195
34.

Impact of mast cells in mucosal immunity of intestinal inflammation: Inhibitory effect of IL-37.

Conti P, Caraffa A, Ronconi G, Kritas SK, Mastrangelo F, Tettamanti L, Theoharides TC.

Eur J Pharmacol. 2018 Jan 5;818:294-299. doi: 10.1016/j.ejphar.2017.09.044. Epub 2017 Sep 29. Review.

PMID:
28970014
35.

Link between mast cells and bacteria: Antimicrobial defense, function and regulation by cytokines.

Conti P, Carinci F, Caraffa A, Ronconi G, Lessiani G, Theoharides TC.

Med Hypotheses. 2017 Sep;106:10-14. doi: 10.1016/j.mehy.2017.06.018. Epub 2017 Jun 29.

PMID:
28818263
36.

Potential therapeutic use of IL-37: a key suppressor of innate immunity and allergic immune responses mediated by mast cells.

Conti P, Carinci F, Lessiani G, Spinas E, Kritas SK, Ronconi G, Caraffa A, Theoharides TC.

Immunol Res. 2017 Oct;65(5):982-986. doi: 10.1007/s12026-017-8938-7. Review.

PMID:
28748328
37.

Mast cell, pro-inflammatory and anti-inflammatory: Jekyll and Hyde, the story continues.

Conti P, Caraffa Al, Kritas SK, Ronconi G, Lessiani G, Toniato E, Theoharides TC.

J Biol Regul Homeost Agents. 2017 Apr-Jun;31(2):263-267.

PMID:
28685525
38.

Tolerability and benefit of a tetramethoxyluteolin-containing skin lotion.

Theoharides TC, Stewart JM, Tsilioni I.

Int J Immunopathol Pharmacol. 2017 Jun;30(2):146-151. doi: 10.1177/0394632017707610. Epub 2017 May 8.

39.

SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors.

Taracanova A, Alevizos M, Karagkouni A, Weng Z, Norwitz E, Conti P, Leeman SE, Theoharides TC.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4002-E4009. doi: 10.1073/pnas.1524845114. Epub 2017 May 1.

40.

Vitamin D and Atopy.

Theoharides TC.

Clin Ther. 2017 May;39(5):880-883. doi: 10.1016/j.clinthera.2017.03.002. Epub 2017 Apr 26. No abstract available.

PMID:
28454657
41.

Mast cells emerge as mediators of atherosclerosis: Special emphasis on IL-37 inhibition.

Conti P, Lessiani G, Kritas SK, Ronconi G, Caraffa A, Theoharides TC.

Tissue Cell. 2017 Jun;49(3):393-400. doi: 10.1016/j.tice.2017.04.002. Epub 2017 Apr 12. Review.

PMID:
28420489
42.

Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells.

Patel AB, Theoharides TC.

J Pharmacol Exp Ther. 2017 Jun;361(3):462-471. doi: 10.1124/jpet.117.240564. Epub 2017 Apr 12.

PMID:
28404689
43.

Neuroendocrinology of mast cells: Challenges and controversies.

Theoharides TC.

Exp Dermatol. 2017 Sep;26(9):751-759. doi: 10.1111/exd.13288. Epub 2017 Apr 2. Review.

PMID:
28094875
44.

Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism.

Patel AB, Tsilioni I, Leeman SE, Theoharides TC.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E7049-E7058. doi: 10.1073/pnas.1604992113. Epub 2016 Sep 23. Erratum in: Proc Natl Acad Sci U S A. 2016 Nov 1;:.

45.
46.

Endocrinology of the skin: intradermal neuroimmune network, a new frontier.

Caraffa Al, Spinas E, Kritas SK, Lessiani G, Ronconi G, Saggini A, Antinolfi P, Pizzicannella J, Toniato E, Theoharides TC, Conti P.

J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2):339-43.

PMID:
27358119
47.

Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders.

Theoharides TC, Tsilioni I, Patel AB, Doyle R.

Transl Psychiatry. 2016 Jun 28;6(6):e844. doi: 10.1038/tp.2016.77. Review.

48.

Neuroendocrinology of the skin.

Theoharides TC, Stewart JM, Taracanova A, Conti P, Zouboulis CC.

Rev Endocr Metab Disord. 2016 Sep;17(3):287-294. Review.

PMID:
27338934
49.

Mast Cells Regulate Wound Healing in Diabetes.

Tellechea A, Leal EC, Kafanas A, Auster ME, Kuchibhotla S, Ostrovsky Y, Tecilazich F, Baltzis D, Zheng Y, Carvalho E, Zabolotny JM, Weng Z, Petra A, Patel A, Panagiotidou S, Pradhan-Nabzdyk L, Theoharides TC, Veves A.

Diabetes. 2016 Jul;65(7):2006-19. doi: 10.2337/db15-0340. Epub 2016 Apr 8.

50.

Danger Signals and Inflammation.

Theoharides TC.

Clin Ther. 2016 May;38(5):996-9. doi: 10.1016/j.clinthera.2016.03.036. Epub 2016 Apr 22. No abstract available.

PMID:
27101818

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