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Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia.

McAllister KA, Mar AC, Theobald DE, Saksida LM, Bussey TJ.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3883-97. doi: 10.1007/s00213-015-4018-7. Epub 2015 Jul 21.


Reconsolidation and extinction are dissociable and mutually exclusive processes: behavioral and molecular evidence.

Merlo E, Milton AL, Goozée ZY, Theobald DE, Everitt BJ.

J Neurosci. 2014 Feb 12;34(7):2422-31. doi: 10.1523/JNEUROSCI.4001-13.2014.


The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.

Eagle DM, Noschang C, d'Angelo LS, Noble CA, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP, Morein-Zamir S, Robbins TW.

Behav Brain Res. 2014 May 1;264:207-29. doi: 10.1016/j.bbr.2013.12.040. Epub 2014 Jan 6.


Approaches for drug delivery with intracortical probes.

Spieth S, Schumacher A, Trenkle F, Brett O, Seidl K, Herwik S, Kisban S, Ruther P, Paul O, Aarts AA, Neves HP, Rich PD, Theobald DE, Holtzman T, Dalley JW, Verhoef BE, Janssen P, Zengerle R.

Biomed Tech (Berl). 2014 Aug;59(4):291-303. doi: 10.1515/bmt-2012-0096. Review.


Gamma aminobutyric acidergic and neuronal structural markers in the nucleus accumbens core underlie trait-like impulsive behavior.

Caprioli D, Sawiak SJ, Merlo E, Theobald DE, Spoelder M, Jupp B, Voon V, Carpenter TA, Everitt BJ, Robbins TW, Dalley JW.

Biol Psychiatry. 2014 Jan 15;75(2):115-23. doi: 10.1016/j.biopsych.2013.07.013. Epub 2013 Aug 21.


Cocaine modulation of frontostriatal expression of Zif268, D2, and 5-HT2c receptors in high and low impulsive rats.

Besson M, Pelloux Y, Dilleen R, Theobald DE, Lyon A, Belin-Rauscent A, Robbins TW, Dalley JW, Everitt BJ, Belin D.

Neuropsychopharmacology. 2013 Sep;38(10):1963-73. doi: 10.1038/npp.2013.95. Epub 2013 May 1.


Divergent effects of D₂/₃ receptor activation in the nucleus accumbens core and shell on impulsivity and locomotor activity in high and low impulsive rats.

Moreno M, Economidou D, Mar AC, López-Granero C, Caprioli D, Theobald DE, Fernando A, Newman AH, Robbins TW, Dalley JW.

Psychopharmacology (Berl). 2013 Jul;228(1):19-30. doi: 10.1007/s00213-013-3010-3. Epub 2013 Feb 14.


Longitudinal relationships between fatigue and depression in cancer patients with depression and/or pain.

Brown LF, Rand KL, Bigatti SM, Stewart JC, Theobald DE, Wu J, Kroenke K.

Health Psychol. 2013 Dec;32(12):1199-208. doi: 10.1037/a0029773. Epub 2012 Aug 27.


Longitudinal comparison of three depression measures in adult cancer patients.

Johns SA, Kroenke K, Krebs EE, Theobald DE, Wu J, Tu W.

J Pain Symptom Manage. 2013 Jan;45(1):71-82. doi: 10.1016/j.jpainsymman.2011.12.284. Epub 2012 Aug 22.


An intra-cerebral drug delivery system for freely moving animals.

Spieth S, Schumacher A, Holtzman T, Rich PD, Theobald DE, Dalley JW, Nouna R, Messner S, Zengerle R.

Biomed Microdevices. 2012 Oct;14(5):799-809. doi: 10.1007/s10544-012-9659-2.


Norepinephrine and dopamine modulate impulsivity on the five-choice serial reaction time task through opponent actions in the shell and core sub-regions of the nucleus accumbens.

Economidou D, Theobald DE, Robbins TW, Everitt BJ, Dalley JW.

Neuropsychopharmacology. 2012 Aug;37(9):2057-66. doi: 10.1038/npp.2012.53. Epub 2012 Apr 18.


Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex.

Murphy ER, Fernando AB, Urcelay GP, Robinson ES, Mar AC, Theobald DE, Dalley JW, Robbins TW.

Psychopharmacology (Berl). 2012 Jan;219(2):401-10. doi: 10.1007/s00213-011-2572-1. Epub 2011 Nov 19.


Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists.

Fernando AB, Economidou D, Theobald DE, Zou MF, Newman AH, Spoelder M, Caprioli D, Moreno M, Hipólito L, Aspinall AT, Robbins TW, Dalley JW.

Psychopharmacology (Berl). 2012 Jan;219(2):341-52. doi: 10.1007/s00213-011-2408-z. Epub 2011 Jul 15.


Prefrontal and monoaminergic contributions to stop-signal task performance in rats.

Bari A, Mar AC, Theobald DE, Elands SA, Oganya KC, Eagle DM, Robbins TW.

J Neurosci. 2011 Jun 22;31(25):9254-63. doi: 10.1523/JNEUROSCI.1543-11.2011.


Contrasting roles for dopamine D1 and D2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats.

Eagle DM, Wong JC, Allan ME, Mar AC, Theobald DE, Robbins TW.

J Neurosci. 2011 May 18;31(20):7349-56. doi: 10.1523/JNEUROSCI.6182-10.2011.


Dissociable effects of lesions to orbitofrontal cortex subregions on impulsive choice in the rat.

Mar AC, Walker AL, Theobald DE, Eagle DM, Robbins TW.

J Neurosci. 2011 Apr 27;31(17):6398-404. doi: 10.1523/JNEUROSCI.6620-10.2011.


Comparison of SF-36 vitality scale and Fatigue Symptom Inventory in assessing cancer-related fatigue.

Brown LF, Kroenke K, Theobald DE, Wu J.

Support Care Cancer. 2011 Aug;19(8):1255-9. doi: 10.1007/s00520-011-1148-2. Epub 2011 Apr 10.


Telecare management of pain and depression in patients with cancer: patient satisfaction and predictors of use.

Johns SA, Kroenke K, Theobald DE, Wu J, Tu W.

J Ambul Care Manage. 2011 Apr-Jun;34(2):126-39. doi: 10.1097/JAC.0b013e31820ef628.


High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress.

Molander AC, Mar A, Norbury A, Steventon S, Moreno M, Caprioli D, Theobald DE, Belin D, Everitt BJ, Robbins TW, Dalley JW.

Psychopharmacology (Berl). 2011 Jun;215(4):721-31. doi: 10.1007/s00213-011-2167-x. Epub 2011 Jan 28.


Enzyme-based choline and L-glutamate biosensor electrodes on silicon microprobe arrays.

Frey O, Holtzman T, McNamara RM, Theobald DE, van der Wal PD, de Rooij NF, Dalley JW, Koudelka-Hep M.

Biosens Bioelectron. 2010 Oct 15;26(2):477-84. doi: 10.1016/j.bios.2010.07.073. Epub 2010 Aug 11.


Yohimbine increases impulsivity through activation of cAMP response element binding in the orbitofrontal cortex.

Sun H, Green TA, Theobald DE, Birnbaum SG, Graham DL, Zeeb FD, Nestler EJ, Winstanley CA.

Biol Psychiatry. 2010 Apr 1;67(7):649-56. doi: 10.1016/j.biopsych.2009.11.030. Epub 2010 Feb 16.


Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats.

Castañé A, Theobald DE, Robbins TW.

Behav Brain Res. 2010 Jun 26;210(1):74-83. doi: 10.1016/j.bbr.2010.02.017. Epub 2010 Feb 12.


Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats.

Bari A, Theobald DE, Caprioli D, Mar AC, Aidoo-Micah A, Dalley JW, Robbins TW.

Neuropsychopharmacology. 2010 May;35(6):1290-301. doi: 10.1038/npp.2009.233. Epub 2010 Jan 27.


Dissociable control of impulsivity in rats by dopamine d2/3 receptors in the core and shell subregions of the nucleus accumbens.

Besson M, Belin D, McNamara R, Theobald DE, Castel A, Beckett VL, Crittenden BM, Newman AH, Everitt BJ, Robbins TW, Dalley JW.

Neuropsychopharmacology. 2010 Jan;35(2):560-9. doi: 10.1038/npp.2009.162.


The association of depression and anxiety with health-related quality of life in cancer patients with depression and/or pain.

Brown LF, Kroenke K, Theobald DE, Wu J, Tu W.

Psychooncology. 2010 Jul;19(7):734-41. doi: 10.1002/pon.1627.


Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens.

Green TA, Alibhai IN, Roybal CN, Winstanley CA, Theobald DE, Birnbaum SG, Graham AR, Unterberg S, Graham DL, Vialou V, Bass CE, Terwilliger EF, Bardo MT, Nestler EJ.

Biol Psychiatry. 2010 Jan 1;67(1):28-35. doi: 10.1016/j.biopsych.2009.06.022.


Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour.

Doe CM, Relkovic D, Garfield AS, Dalley JW, Theobald DE, Humby T, Wilkinson LS, Isles AR.

Hum Mol Genet. 2009 Jun 15;18(12):2140-8. doi: 10.1093/hmg/ddp137. Epub 2009 Mar 20.


DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine.

Winstanley CA, Green TA, Theobald DE, Renthal W, LaPlant Q, DiLeone RJ, Chakravarty S, Nestler EJ.

Pharmacol Biochem Behav. 2009 Sep;93(3):278-84. doi: 10.1016/j.pbb.2008.12.007. Epub 2008 Dec 16.


Serotonin depletion impairs waiting but not stop-signal reaction time in rats: implications for theories of the role of 5-HT in behavioral inhibition.

Eagle DM, Lehmann O, Theobald DE, Pena Y, Zakaria R, Ghosh R, Dalley JW, Robbins TW.

Neuropsychopharmacology. 2009 Apr;34(5):1311-21. doi: 10.1038/npp.2008.202. Epub 2008 Nov 12.


Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: specific deficits in 'waiting' versus 'stopping'.

Robinson ES, Eagle DM, Economidou D, Theobald DE, Mar AC, Murphy ER, Robbins TW, Dalley JW.

Behav Brain Res. 2009 Jan 23;196(2):310-6. doi: 10.1016/j.bbr.2008.09.021. Epub 2008 Oct 2.


Contrasting effects of selective lesions of nucleus accumbens core or shell on inhibitory control and amphetamine-induced impulsive behaviour.

Murphy ER, Robinson ES, Theobald DE, Dalley JW, Robbins TW.

Eur J Neurosci. 2008 Jul;28(2):353-63. doi: 10.1111/j.1460-9568.2008.06309.x.


Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex.

Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ.

Cereb Cortex. 2009 Feb;19(2):435-44. doi: 10.1093/cercor/bhn094. Epub 2008 Jun 6.


Opposing roles for 5-HT2A and 5-HT2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time task.

Robinson ES, Dalley JW, Theobald DE, Glennon JC, Pezze MA, Murphy ER, Robbins TW.

Neuropsychopharmacology. 2008 Sep;33(10):2398-406. Epub 2007 Nov 28.


DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.

Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ.

J Neurosci. 2007 Sep 26;27(39):10497-507.


Lesions of the dorsal noradrenergic bundle impair attentional set-shifting in the rat.

Tait DS, Brown VJ, Farovik A, Theobald DE, Dalley JW, Robbins TW.

Eur J Neurosci. 2007 Jun;25(12):3719-24.


Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.

Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Lääne K, Peña Y, Murphy ER, Shah Y, Probst K, Abakumova I, Aigbirhio FI, Richards HK, Hong Y, Baron JC, Everitt BJ, Robbins TW.

Science. 2007 Mar 2;315(5816):1267-70.


IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates.

Russo SJ, Bolanos CA, Theobald DE, DeCarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ.

Nat Neurosci. 2007 Jan;10(1):93-9. Epub 2006 Dec 3.


Selective depletion of cortical noradrenaline by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat.

Milstein JA, Lehmann O, Theobald DE, Dalley JW, Robbins TW.

Psychopharmacology (Berl). 2007 Jan;190(1):51-63. Epub 2006 Nov 10.


Enduring deficits in sustained visual attention during withdrawal of intravenous methylenedioxymethamphetamine self-administration in rats: results from a comparative study with d-amphetamine and methamphetamine.

Dalley JW, Lääne K, Theobald DE, Peña Y, Bruce CC, Huszar AC, Wojcieszek M, Everitt BJ, Robbins TW.

Neuropsychopharmacology. 2007 May;32(5):1195-206. Epub 2006 Oct 11.


Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli.

Green TA, Alibhai IN, Hommel JD, DiLeone RJ, Kumar A, Theobald DE, Neve RL, Nestler EJ.

J Neurosci. 2006 Aug 9;26(32):8235-42.


An open label pilot study of citalopram for depression and boredom in ambulatory cancer patients.

Theobald DE, Kirsh KL, Holtsclaw E, Donaghy K, Passik SD.

Palliat Support Care. 2003 Mar;1(1):71-7.


A chart review, pilot study of two single-item screens to detect cancer patients at risk for cachexia.

Kirsh KL, Dugan C, Theobald DE, Passik SD.

Palliat Support Care. 2003 Dec;1(4):331-5.


Epigenetic mechanisms and gene networks in the nervous system.

Colvis CM, Pollock JD, Goodman RH, Impey S, Dunn J, Mandel G, Champagne FA, Mayford M, Korzus E, Kumar A, Renthal W, Theobald DE, Nestler EJ.

J Neurosci. 2005 Nov 9;25(45):10379-89. Review. No abstract available.


Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum.

Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ.

Neuron. 2005 Oct 20;48(2):303-14.


Attentional and motivational deficits in rats withdrawn from intravenous self-administration of cocaine or heroin.

Dalley JW, Lääne K, Pena Y, Theobald DE, Everitt BJ, Robbins TW.

Psychopharmacology (Berl). 2005 Nov;182(4):579-87. Epub 2005 Oct 19.


Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens.

Dalley JW, Lääne K, Theobald DE, Armstrong HC, Corlett PR, Chudasama Y, Robbins TW.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6189-94. Epub 2005 Apr 15.


Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice.

Winstanley CA, Theobald DE, Dalley JW, Cardinal RN, Robbins TW.

Cereb Cortex. 2006 Jan;16(1):106-14. Epub 2005 Apr 13.


Access to communication technologies in a sample of cancer patients: an urban and rural survey.

Abdullah M, Theobald DE, Butler D, Kroenke K, Perkins A, Edgerton S, Dugan WM Jr.

BMC Cancer. 2005 Feb 17;5:18.


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