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Items: 1 to 50 of 56

1.

New metabolic and pharmacokinetic characteristics of thiocolchicoside and its active metabolite in healthy humans.

Trellu M, Filali-Ansary A, Françon D, Adam R, Lluel P, Dubruc C, Thénot JP.

Fundam Clin Pharmacol. 2004 Aug;18(4):493-501.

PMID:
15312157
2.

Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process.

Lançon A, Delmas D, Osman H, Thénot JP, Jannin B, Latruffe N.

Biochem Biophys Res Commun. 2004 Apr 16;316(4):1132-7.

PMID:
15044102
3.

Subliminal Fas stimulation increases the hepatotoxicity of acetaminophen and bromobenzene in mice.

Tinel M, Berson A, Vadrot N, Descatoire V, Grodet A, Feldmann G, Thénot JP, Pessayre D.

Hepatology. 2004 Mar;39(3):655-66.

PMID:
14999684
4.

Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates.

Hartman NR, Cysyk RL, Bruneau-Wack C, Thénot JP, Parker RJ, Strong JM.

Chem Biol Interact. 2002 Nov 10;142(1-2):43-55.

PMID:
12399154
5.

Population pharmacokinetic analysis and optimization of the experimental design for mizolastine solution in children.

Mentré F, Dubruc C, Thénot JP.

J Pharmacokinet Pharmacodyn. 2001 Jun;28(3):299-319.

PMID:
11468942
6.

Population pharmacokinetic analysis of mizolastine and validation from sparse data on patients using the nonparametric maximum likelihood method.

Mesnil F, Mentré F, Dubruc C, Thénot JP, Mallet A.

J Pharmacokinet Biopharm. 1998 Apr;26(2):133-61.

PMID:
9795879
7.

Pharmacokinetic analysis of mizolastine in healthy young volunteers after single oral and intravenous doses: noncompartmental approach and compartmental modeling.

Mesnil F, Dubruc C, Mentre F, Huet S, Mallet A, Thenot JP.

J Pharmacokinet Biopharm. 1997 Apr;25(2):125-47.

PMID:
9408856
8.

Plasma and skin suction-blister-fluid pharmacokinetics and time course of the effects of oral mizolastine.

Chosidow O, Dubruc C, Danjou P, Fuseau E, Espagne E, Bianchetti G, Thenot JP, Herson S, Rosenzweig P, Revuz J.

Eur J Clin Pharmacol. 1996;50(4):327-33.

PMID:
8803528
9.

Oxidative metabolism of zolpidem by human liver cytochrome P450S.

Pichard L, Gillet G, Bonfils C, Domergue J, Thénot JP, Maurel P.

Drug Metab Dispos. 1995 Nov;23(11):1253-62.

PMID:
8591727
10.
11.

A noncompetitive enzyme immunoassay for rat prolactin.

Tavernier V, Thénot JP, Parrod M, Bromet N.

J Immunoassay. 1995 Feb;16(1):81-96.

PMID:
7775663
12.

Pharmacokinetic and bioavailability of diltiazem sustained-release: influence of food and time of administration.

Bianchetti G, Bagheri H, Houin G, Dubruc C, Thénot JP.

Fundam Clin Pharmacol. 1995;9(2):197-201.

PMID:
7628834
13.
14.

Comparative pharmacokinetic profile of two imidazopyridine drugs: zolpidem and alpidem.

Durand A, Thénot JP, Bianchetti G, Morselli PL.

Drug Metab Rev. 1992;24(2):239-66. Review. No abstract available.

PMID:
1576937
15.

[Videotherapy. Games of looking and projection of the imagination].

Thénot JP.

Soins Psychiatr. 1991 May;(127):15-9. French. No abstract available.

PMID:
1853258
16.

The disposition and pharmacokinetics of alpidem, a new anxiolytic, in the rat.

Garrigou-Gadenne D, Durand A, Thenot JP, Morselli PL.

Drug Metab Dispos. 1991 May-Jun;19(3):574-9.

PMID:
1680622
17.

Clinical pharmacokinetics and tolerability of alpidem in healthy subjects given increasing single doses.

Jonkman JH, Bianchetti G, Grasmeijer G, Oosterhuis B, Thiercelin JF, Thénot JP, Guillet P, Morselli PL.

Eur J Clin Pharmacol. 1991;41(4):369-74.

PMID:
1687121
18.

Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.

Pichard L, Gillet G, Fabre I, Dalet-Beluche I, Bonfils C, Thenot JP, Maurel P.

Drug Metab Dispos. 1990 Sep-Oct;18(5):711-9.

PMID:
1981725
20.

Pharmacokinetics, brain distribution and pharmaco-electrocorticographic profile of zolpidem, a new hypnotic, in the rat.

Garrigou-Gadenne D, Burke JT, Durand A, Depoortere H, Thénot JP, Morselli PL.

J Pharmacol Exp Ther. 1989 Mar;248(3):1283-8.

PMID:
2703975
21.

Pharmacokinetics of antihypertensive drugs in the neonatal period.

Morselli PL, Boutroy MJ, Bianchetti G, Thénot JP.

Dev Pharmacol Ther. 1989;13(2-4):190-8. Review.

PMID:
2693002
22.

Zolpidem excretion in breast milk.

Pons G, Francoual C, Guillet P, Moran C, Hermann P, Bianchetti G, Thiercelin JF, Thenot JP, Olive G.

Eur J Clin Pharmacol. 1989;37(3):245-8.

PMID:
2612539
23.

Thermospray liquid chromatography tandem mass spectrometry: application to the elucidation of zolpidem metabolism.

Vajta S, Thenot JP, de Maack F, Devant G, Lesieur M.

Biomed Environ Mass Spectrom. 1988 Feb 15;15(4):223-8.

PMID:
3370362
24.

Correlation between reversed-phase high-performance liquid chromatography and plasma protein binding.

Ganansia J, Bianchetti G, Thénot JP.

J Chromatogr. 1987 Oct 9;421(1):83-90.

PMID:
2892848
25.

A preliminary metabolic study of alpidem in rat and man.

Padovani P, Guinebault P, Vajta S, Durand A, Allen J, Thenot JP, Morselli PL.

Eur J Drug Metab Pharmacokinet. 1987 Oct-Dec;12(4):295-8.

PMID:
3449388
26.

[Demonstration in healthy volunteers of the partial agonist effect of a cardioselective beta-blocker, cicloprolol].

Grilliat JP, Le Van D, Mayeux D, Régnier F, Thiercelin JF, Thenot JP, Orofiamma B, Larribaud J.

Therapie. 1987 Oct-Dec;42(6):519-24. French. No abstract available.

PMID:
2894724
27.

Effect of erythrocytes and plasma protein binding on the transport of progabide and SL 75102 through the rat blood-brain barrier.

Hamberger C, Urien S, Essassi D, Grimaldi B, Barre J, Taiclet A, Thenot JP, Tillement JP.

Biochem Pharmacol. 1987 Aug 15;36(16):2641-5.

PMID:
3606664
28.

Determination of S-carboxymethyl-L-cysteine in plasma by high-performance liquid chromatography with column switching following precolumn derivatization.

Dubruc C, Hermann P, Haddouche A, Badarani MM, Thénot JP.

J Chromatogr. 1987 Jun 5;417(1):208-15. No abstract available.

PMID:
3624399
29.

Progabide and SL 75102 binding to plasma proteins and red blood cells in humans.

Hamberger C, Barre J, Brandebourger M, Urien S, Taiclet A, Thenot JP, Tillement JP.

Int J Clin Pharmacol Ther Toxicol. 1987 Apr;25(4):178-84.

PMID:
3583466
30.

Pharmacokinetic interactions of progabide with other antiepileptic drugs.

Bianchetti G, Padovani P, Thénot JP, Thiercelin JF, Morselli PL.

Epilepsia. 1987 Jan-Feb;28(1):68-73.

PMID:
3098557
31.

High-performance liquid chromatographic determination of zolpidem, a new sleep inducer, in biological fluids with fluorimetric detection.

Guinebault P, Dubruc C, Hermann P, Thénot JP.

J Chromatogr. 1986 Nov 28;383(1):206-11. No abstract available.

PMID:
3818839
32.

High-performance liquid chromatographic determination of alfuzosin in biological fluids with fluorimetric detection and large-volume injection.

Guinebault P, Broquaire M, Colafranceschi C, Thénot JP.

J Chromatogr. 1986 Feb 26;353:361-9.

PMID:
2871035
33.
34.

Clonazepam pharmacokinetics and therapeutic efficacy in neonatal seizures.

André M, Boutroy MJ, Dubruc C, Thenot JP, Bianchetti G, Sola L, Vert P, Morselli PL.

Eur J Clin Pharmacol. 1986;30(5):585-9.

PMID:
3758147
35.

Pharmacokinetics of betaxolol in middle aged patients.

Bianchetti G, Thiercelin JF, Thenot JP.

Eur J Clin Pharmacol. 1986;31(2):231-3.

PMID:
2879735
36.

Determination of antiepileptic drugs.

Burke JT, Thénot JP.

J Chromatogr. 1985 May 10;340:199-241. Review.

PMID:
3926805
38.

Determination of betaxolol, a new beta-blocker, by gas chromatography mass spectrometry: application to pharmacokinetic studies.

Hermann P, Fraisse J, Allen J, Morselli PL, Thenot JP.

Biomed Mass Spectrom. 1984 Jan;11(1):29-34.

PMID:
6142735
39.

Isolated lung perfusion with Adriamycin. A preclinical study.

Johnston MR, Minchin R, Shull JH, Thenot JP, McManus BM, Terrill R, Boyd MR.

Cancer. 1983 Aug 1;52(3):404-9.

PMID:
6861081
40.

Pharmacokinetics of diltiazem after intravenous and oral administration.

Hermann P, Rodger SD, Remones G, Thenot JP, London DR, Morselli PL.

Eur J Clin Pharmacol. 1983;24(3):349-52.

PMID:
6861848
41.

Determination of tolazoline in plasma by high-performance liquid chromatography.

Rovei V, Remones G, Thenot JP, Morselli PL.

J Chromatogr. 1982 Aug 13;231(1):210-5. No abstract available.

PMID:
7119061
42.

Identification of desethyl procainamide in patients: a new metabolite of procainamide.

Ruo TI, Morita Y, Atkinson AJ Jr, Henthorn T, Thenot JP.

J Pharmacol Exp Ther. 1981 Feb;216(2):357-62.

PMID:
6162026
43.

Plasma concentrations of desethyl N-acetylprocainamide in patients treated with procainamide and N-acetylprocainamide.

Ruo TI, Thenot JP, Stec GP, Atkinson AJ Jr.

Ther Drug Monit. 1981;3(3):231-7.

PMID:
6172888
44.

Kinetics of N-acetylprocainamide deacetylation.

Stec GP, Ruo TI, Thenot JP, Atkinson AJ Jr, Morita Y, Lertora JJ.

Clin Pharmacol Ther. 1980 Nov;28(5):659-66.

PMID:
6160014
45.

Impact of active metabolites on monitoring plasma concentrations of therapeutic drugs.

Atkinson AJ Jr, Stec GP, Lertora JJ, Ruo TI, Thenot JP.

Ther Drug Monit. 1980;2(1):19-27. Review.

PMID:
6762700
46.

N-Acetylprocainamide pharmacokinetics in functionally anephric patients before and after perturbation by hemodialysis.

Stec GP, Atkinson AJ Jr, Nevin MJ, Thenot JP, Ruo TI, Gibson TP, Ivanovich P, del Greco F.

Clin Pharmacol Ther. 1979 Nov;26(5):618-28.

PMID:
91468
47.

Genetic effects of hydralazine.

Shaw CR, Butler MA, Thenot JP, Haegle KD, Matney TS.

Mutat Res. 1979 Sep;68(1):79-84.

PMID:
386111
48.

Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol.

Blum A, Gold MD, Ames BN, Jones FR, Hett EA, Dougherty RC, Horning EC, Dzidic I, Carroll DI, Stillwell RN, Thenot JP.

Science. 1978 Sep 15;201(4360):1020-3.

PMID:
684422
49.

Methylthio metabolites of naphthalen excreted by the rat.

Stillwell WG, Bouwsma OJ, Thenot JP, Horning MG, Griffin GW, Ishikawa K, Takaku M.

Res Commun Chem Pathol Pharmacol. 1978 Jun;20(3):509-30.

PMID:
674829
50.

Metabolism of diethylstilbestrol in the C3H mouse: chromatographic systems for the quantitative analysis of DES metabolic products.

Helton ED, Gough BJ, King JW Jr, Thenot JP, Horning EC.

Steroids. 1978 Apr;31(4):471-84.

PMID:
663980

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