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Items: 1 to 50 of 80

1.

Lifespan differences in emotional contagion while watching emotion-eliciting videos.

Ruffman T, Then R, Cheng C, Imuta K.

PLoS One. 2019 Jan 18;14(1):e0209253. doi: 10.1371/journal.pone.0209253. eCollection 2019.

2.

Interhemispheric subdural and subarachnoid haemorrhage in a patient with amphetamine-induced vasculitis.

Nagele EP, Ross A, Then RK, Kavi T.

BMJ Case Rep. 2017 Dec 7;2017. pii: bcr-2017-222918. doi: 10.1136/bcr-2017-222918. No abstract available.

3.

Multiple recurrent ischaemic strokes in a patient with cancer: is there a role for the initiation of anticoagulation therapy for secondary stroke prevention?

Suero-Abreu GA, Cheng JZ, Then RK.

BMJ Case Rep. 2017 Jun 3;2017. pii: bcr-2016-218105. doi: 10.1136/bcr-2016-218105.

4.

Paroxysmal sneezing heralding embolic cerebral infarction.

Then R, Dominguez F, Robbins MS.

J Am Geriatr Soc. 2013 Jan;61(1):168-9. doi: 10.1111/jgs.12052. No abstract available.

PMID:
23311563
5.
6.

The targets of currently used antibacterial agents: lessons for drug discovery.

Lange RP, Locher HH, Wyss PC, Then RL.

Curr Pharm Des. 2007;13(30):3140-54. Review.

PMID:
17979755
7.

DNA and RNA synthesis: antifolates.

Kompis IM, Islam K, Then RL.

Chem Rev. 2005 Feb;105(2):593-620. Review. No abstract available.

PMID:
15700958
8.
9.

New anti-MRSA and anti-VRE carbapenems; synthesis and structure-activity relationships of 1beta-methyl-2-(thiazol-2-ylthio)carbapenems.

Sunagawa M, Itoh M, Kubota K, Sasaki A, Ueda Y, Angehrn P, Bourson A, Goetschi E, Hebeisen P, Then RL.

J Antibiot (Tokyo). 2002 Aug;55(8):722-57.

10.

In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci.

Hebeisen P, Heinze-Krauss I, Angehrn P, Hohl P, Page MG, Then RL.

Antimicrob Agents Chemother. 2001 Mar;45(3):825-36.

11.

Mode of action of sulfanilyl fluoroquinolones.

Alovero F, Nieto M, Mazzieri MR, Then R, Manzo RH.

Antimicrob Agents Chemother. 1998 Jun;42(6):1495-8.

12.

Structure and function of the dihydropteroate synthase from Staphylococcus aureus.

Hampele IC, D'Arcy A, Dale GE, Kostrewa D, Nielsen J, Oefner C, Page MG, Schönfeld HJ, Stüber D, Then RL.

J Mol Biol. 1997 Apr 25;268(1):21-30.

PMID:
9149138
13.

A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance.

Dale GE, Broger C, D'Arcy A, Hartman PG, DeHoogt R, Jolidon S, Kompis I, Labhardt AM, Langen H, Locher H, Page MG, Stüber D, Then RL, Wipf B, Oefner C.

J Mol Biol. 1997 Feb 14;266(1):23-30.

PMID:
9054967
14.

Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone.

Locher HH, Schlunegger H, Hartman PG, Angehrn P, Then RL.

Antimicrob Agents Chemother. 1996 Jun;40(6):1376-81.

15.
17.
18.

Activity of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone against Toxoplasma gondii.

Chang HR, Arsenijevic D, Comte R, Polak A, Then RL, Pechère JC.

Antimicrob Agents Chemother. 1994 Aug;38(8):1803-7.

19.

History and future of antimicrobial diaminopyrimidines.

Then RL.

J Chemother. 1993 Dec;5(6):361-8.

PMID:
8195827
20.
21.

(6R)-6-(substituted methyl)penicillanic acid sulfones: new potent beta-lactamase inhibitors.

Adam S, Then R, Angehrn P.

J Antibiot (Tokyo). 1993 Apr;46(4):641-6.

22.

Selective inhibition of dihydrofolate reductase from problem human pathogens.

Then RL, Hartman PG, Kompis I, Santi D.

Adv Exp Med Biol. 1993;338:533-6. No abstract available.

PMID:
8304174
23.

Antibacterial properties of Ro 40-6890, a broad-spectrum cephalosporin, and its novel orally absorbable ester, Ro 41-3399.

Angehrn P, Hohl P, Hubschwerlen C, Page M, Then R.

Antimicrob Agents Chemother. 1992 Dec;36(12):2825-34.

24.

Dual-action penems and carbapenems.

Corraz AJ, Dax SL, Dunlap NK, Georgopapadakou NH, Keith DD, Pruess DL, Rossman PL, Then R, Unowsky J, Wei CC.

J Med Chem. 1992 May 15;35(10):1828-39.

PMID:
1588561
26.

Methylene (2S,5R)-6-(3-formylallylidene)penicillanate pivalate, a prodrug of a new beta-lactamase inhibitor.

Adam S, Then R, Angehrn P.

J Antibiot (Tokyo). 1992 Apr;45(4):587-8. No abstract available.

27.
28.

Lipopolysaccharide alterations responsible for combined quinolone and beta-lactam resistance in Pseudomonas aeruginosa.

Leying HJ, Büscher KH, Cullmann W, Then RL.

Chemotherapy. 1992;38(2):82-91.

PMID:
1591950
29.

In vitro and in vivo evaluation of Ro 09-1428, a new parenteral cephalosporin with high antipseudomonal activity.

Arisawa M, Sekine Y, Shimizu S, Takano H, Angehrn P, Then RL.

Antimicrob Agents Chemother. 1991 Apr;35(4):653-9.

30.
31.

Permeability and penicillin-binding protein alterations in Salmonella muenchen: stepwise resistance acquired during beta-lactam therapy.

Bellido F, Vladoïanu IR, Auckenthaler R, Suter S, Wacker P, Then RL, Pechère JC.

Antimicrob Agents Chemother. 1989 Jul;33(7):1113-5.

32.
33.
34.

Biochemical characterization of type A and type B beta-lactamase from Enterobacter cloacae.

Then RL, Charnas RL, Kocher HP, Manneberg M, Röthlisberger U, Stocker J.

Rev Infect Dis. 1988 Jul-Aug;10(4):714-20.

PMID:
3263683
35.

Mechanism of inhibition of chromosomal beta-lactamases by third-generation cephalosporins.

Charnas RL, Then RL.

Rev Infect Dis. 1988 Jul-Aug;10(4):752-60.

PMID:
3142012
36.

Properties of aditoprim, a new antibacterial dihydrofolate reductase inhibitor.

Then RL, Keller M.

Zentralbl Veterinarmed B. 1988 Feb;35(2):114-20. No abstract available.

PMID:
3420982
37.

Reduced expression of outer-membrane proteins in beta-lactam-resistant mutants of Enterobacter cloacae.

Aggeler R, Then RL, Ghosh R.

J Gen Microbiol. 1987 Dec;133(12):3383-92.

PMID:
3503923
38.
39.

6-(E)-acetylmethylenepenicillanic acid, a potent beta-lactamase inhibitor.

Adam S, Then RL, Angehrn P.

J Antibiot (Tokyo). 1987 Jan;40(1):108-9. No abstract available.

40.

Multiply resistant mutants of Enterobacter cloacae selected by beta-lactam antibiotics.

Then RL, Angehrn P.

Antimicrob Agents Chemother. 1986 Nov;30(5):684-8.

41.

Potential prodrugs of 6-acetylmethylenepenicillanic acid (Ro 15-1903).

Adam S, Then R, Angehrn P.

J Antibiot (Tokyo). 1986 Jun;39(6):833-8.

42.
43.

Affinity of carumonam for penicillin-binding proteins.

Then RL, Kohl I.

Chemotherapy. 1985;31(4):246-54.

PMID:
3928279
44.

A 1H NMR study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase.

Birdsall B, Feeney J, Pascual C, Roberts GC, Kompis I, Then RL, Müller K, Kroehn A.

J Med Chem. 1984 Dec;27(12):1672-6.

PMID:
6438320
45.

Properties of brodimoprim as an inhibitor of dihydrofolate reductases.

Then RL, Hermann F.

Chemotherapy. 1984;30(1):18-25.

PMID:
6363003
46.

Interaction of Ro 17-2301 (AMA-1080) with beta-lactamases.

Then RL.

Chemotherapy. 1984;30(6):398-407.

PMID:
6335074
48.

Cephalosporin resistance in strains of Klebsiella oxytoca isolated during antibiotic therapy.

Then RL, Glauser MP, Angehrn P, Arisawa M.

Zentralbl Bakteriol Mikrobiol Hyg A. 1983 Jul;254(4):469-79.

PMID:
6609500
49.

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