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Items: 17

1.

The Novel Activity of Carbamazepine as an Activation Modulator Extends from NaV1.7 Mutations to the NaV1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy.

Han C, Themistocleous AC, Estacion M, Dib-Hajj FB, Blesneac I, Macala L, Fratter C, Bennett DL, Waxman SG, Dib-Hajj SD.

Mol Pharmacol. 2018 Nov;94(5):1256-1269. doi: 10.1124/mol.118.113076. Epub 2018 Aug 22.

PMID:
30135145
2.

Using stratified medicine to understand, diagnose, and treat neuropathic pain.

Themistocleous AC, Crombez G, Baskozos G, Bennett DL.

Pain. 2018 Sep;159 Suppl 1:S31-S42. doi: 10.1097/j.pain.0000000000001301. No abstract available.

PMID:
30113945
3.

Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients.

Sieberg CB, Taras C, Gomaa A, Nickerson C, Wong C, Ward C, Baskozos G, Bennett DLH, Ramirez JD, Themistocleous AC, Rice ASC, Shillo PR, Tesfaye S, Edwards RR, Andrews NA, Berde C, Costigan M.

Pain Rep. 2018 May 24;3(3):e651. doi: 10.1097/PR9.0000000000000651. eCollection 2018 May.

4.

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability.

Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck LJ, Sheridan J, Shakir A, Jacobson L, Gutierrez-Mecinas M, Galino J, Walcher J, Kühnemund J, Kuehn H, Sanna MD, Lang B, Clark AJ, Themistocleous AC, Iwagaki N, West SJ, Werynska K, Carroll L, Trendafilova T, Menassa DA, Giannoccaro MP, Coutinho E, Cervellini I, Tewari D, Buckley C, Leite MI, Wildner H, Zeilhofer HU, Peles E, Todd AJ, McMahon SB, Dickenson AH, Lewin GR, Vincent A, Bennett DL.

Neuron. 2018 Feb 21;97(4):806-822.e10. doi: 10.1016/j.neuron.2018.01.033. Epub 2018 Feb 8.

5.

A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy.

Segerdahl AR, Themistocleous AC, Fido D, Bennett DL, Tracey I.

Brain. 2018 Feb 1;141(2):357-364. doi: 10.1093/brain/awx337.

6.

Reply: Non-freezing cold injury: a multi-faceted syndrome.

Vale TA, Symmonds M, Polydefkis M, Byrnes K, Rice ASC, Themistocleous AC, Bennett DLH.

Brain. 2018 Feb 1;141(2):e10. doi: 10.1093/brain/awx325. No abstract available.

PMID:
29315377
7.

Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy.

Blesneac I, Themistocleous AC, Fratter C, Conrad LJ, Ramirez JD, Cox JJ, Tesfaye S, Shillo PR, Rice ASC, Tucker SJ, Bennett DLH.

Pain. 2018 Mar;159(3):469-480. doi: 10.1097/j.pain.0000000000001116.

8.

Chronic non-freezing cold injury results in neuropathic pain due to a sensory neuropathy.

Vale TA, Symmonds M, Polydefkis M, Byrnes K, Rice ASC, Themistocleous AC, Bennett DLH.

Brain. 2017 Oct 1;140(10):2557-2569. doi: 10.1093/brain/awx215.

9.

Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations.

Vollert J, Maier C, Attal N, Bennett DLH, Bouhassira D, Enax-Krumova EK, Finnerup NB, Freynhagen R, Gierthmühlen J, Haanpää M, Hansson P, Hüllemann P, Jensen TS, Magerl W, Ramirez JD, Rice ASC, Schuh-Hofer S, Segerdahl M, Serra J, Shillo PR, Sindrup S, Tesfaye S, Themistocleous AC, Tölle TR, Treede RD, Baron R.

Pain. 2017 Aug;158(8):1446-1455. doi: 10.1097/j.pain.0000000000000935.

10.

Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies.

Auer-Grumbach M, Toegel S, Schabhüttl M, Weinmann D, Chiari C, Bennett DLH, Beetz C, Klein D, Andersen PM, Böhme I, Fink-Puches R, Gonzalez M, Harms MB, Motley W, Reilly MM, Renner W, Rudnik-Schöneborn S, Schlotter-Weigel B, Themistocleous AC, Weishaupt JH, Ludolph AC, Wieland T, Tao F, Abreu L, Windhager R, Zitzelsberger M, Strom TM, Walther T, Scherer SS, Züchner S, Martini R, Senderek J.

Am J Hum Genet. 2016 Sep 1;99(3):607-623. doi: 10.1016/j.ajhg.2016.07.008.

11.

The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy.

Themistocleous AC, Ramirez JD, Shillo PR, Lees JG, Selvarajah D, Orengo C, Tesfaye S, Rice AS, Bennett DL.

Pain. 2016 May;157(5):1132-45. doi: 10.1097/j.pain.0000000000000491.

12.

Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception.

Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J.

Nat Genet. 2015 Aug;47(8):962. doi: 10.1038/ng0815-962b. No abstract available.

PMID:
26220135
13.

Transcriptional regulator PRDM12 is essential for human pain perception.

Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J.

Nat Genet. 2015 Jul;47(7):803-8. doi: 10.1038/ng.3308. Epub 2015 May 25. Erratum in: Nat Genet. 2015 Aug;47(8):962.

PMID:
26005867
14.

Late onset hereditary sensory and autonomic neuropathy with cognitive impairment associated with Y163X prion mutation.

Themistocleous AC, Kennett R, Husain M, Palace J, Mead S, Bennett DL.

J Neurol. 2014 Nov;261(11):2230-3. doi: 10.1007/s00415-014-7521-6. Epub 2014 Oct 7. No abstract available.

15.

Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.

Ramirez JD, Habib AM, Cox JJ, Themistocleous AC, McMahon SB, Wood JN, Bennett DL.

Neurology. 2014 Oct 21;83(17):1577-80. doi: 10.1212/WNL.0000000000000913. Epub 2014 Sep 24. No abstract available.

16.

The clinical approach to small fibre neuropathy and painful channelopathy.

Themistocleous AC, Ramirez JD, Serra J, Bennett DL.

Pract Neurol. 2014 Dec;14(6):368-79. doi: 10.1136/practneurol-2013-000758. Epub 2014 Apr 28. Review.

17.

The time course of inflammatory cytokine secretion in a rat model of postoperative pain does not coincide with the onset of mechanical hyperalgesia.

Loram LC, Themistocleous AC, Fick LG, Kamerman PR.

Can J Physiol Pharmacol. 2007 Jun;85(6):613-20.

PMID:
17823623

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