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Items: 1 to 50 of 769

1.

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Rehorst WA, Thelen MP, Nolte H, Türk C, Cirak S, Peterson JM, Wong GW, Wirth B, Krüger M, Winter D, Kye MJ.

Acta Neuropathol Commun. 2019 Oct 15;7(1):154. doi: 10.1186/s40478-019-0806-3.

2.

Fast 0/1-h algorithm for detection of NSTEMI: are current high-sensitivity cardiac troponin assays fit for purpose? An EQA-based evaluation.

van der Hagen EAE, Cobbaert CM, Meijer R, Thelen MHM.

Clin Chem Lab Med. 2019 Jul 20. pii: /j/cclm.ahead-of-print/cclm-2019-0253/cclm-2019-0253.xml. doi: 10.1515/cclm-2019-0253. [Epub ahead of print]

PMID:
31326959
3.

Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking.

Schmidtke C, Tiede S, Thelen M, Käkelä R, Jabs S, Makrypidi G, Sylvester M, Schweizer M, Braren I, Brocke-Ahmadinejad N, Cotman SL, Schulz A, Gieselmann V, Braulke T.

J Biol Chem. 2019 Jun 14;294(24):9592-9604. doi: 10.1074/jbc.RA119.008852. Epub 2019 Apr 30.

PMID:
31040178
4.

Guanidine Riboswitch-Regulated Efflux Transporters Protect Bacteria against Ionic Liquid Toxicity.

Higgins DA, Gladden JM, Kimbrel JA, Simmons BA, Singer SW, Thelen MP.

J Bacteriol. 2019 Jun 10;201(13). pii: e00069-19. doi: 10.1128/JB.00069-19. Print 2019 Jul 1.

5.

A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five.

Khundadze M, Ribaudo F, Hussain A, Rosentreter J, Nietzsche S, Thelen M, Winter D, Hoffmann B, Afzal MA, Hermann T, de Heus C, Piskor EM, Kosan C, Franzka P, von Kleist L, Stauber T, Klumperman J, Damme M, Proikas-Cezanne T, Hübner CA.

Neurobiol Dis. 2019 Jul;127:419-431. doi: 10.1016/j.nbd.2019.03.026. Epub 2019 Mar 28.

PMID:
30930081
6.

The effects of cryotherapy on quadriceps electromyographic activity and isometric strength in patient in the early phases following knee surgery.

Loro WA, Thelen MD, Rosenthal MD, Stoneman PD, Ross MD.

J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499019831454. doi: 10.1177/2309499019831454.

PMID:
30803326
7.

Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma.

Lechner A, Schlößer HA, Thelen M, Wennhold K, Rothschild SI, Gilles R, Quaas A, Siefer OG, Huebbers CU, Cukuroglu E, Göke J, Hillmer A, Gathof B, Meyer MF, Klussmann JP, Shimabukuro-Vornhagen A, Theurich S, Beutner D, von Bergwelt-Baildon M.

Oncoimmunology. 2019 Jan 10;8(3):1535293. doi: 10.1080/2162402X.2018.1535293. eCollection 2019.

8.

ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens.

Proietti M, Perruzza L, Scribano D, Pellegrini G, D'Antuono R, Strati F, Raffaelli M, Gonzalez SF, Thelen M, Hardt WD, Slack E, Nicoletti M, Grassi F.

Nat Commun. 2019 Jan 16;10(1):250. doi: 10.1038/s41467-018-08156-z.

9.

Quality Monitoring of a FIT-Based Colorectal Cancer Screening Program.

Toes-Zoutendijk E, Bonfrer JMG, Ramakers C, Thelen M, Spaander MCW, Dekker E, van der Meulen MP, Buskermolen M, van Vuuren AJ, Kuipers EJ, van Kemenade FJ, van Velthuysen MF, Thomeer MGJ, van Veldhuizen H, van Ballegooijen M, de Koning HJ, van Leerdam ME, Lansdorp-Vogelaar I.

Clin Chem. 2019 Mar;65(3):419-426. doi: 10.1373/clinchem.2018.294041. Epub 2019 Jan 16.

PMID:
30651228
10.

B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies.

Schlößer HA, Thelen M, Lechner A, Wennhold K, Garcia-Marquez MA, Rothschild SI, Staib E, Zander T, Beutner D, Gathof B, Gilles R, Cukuroglu E, Göke J, Shimabukuro-Vornhagen A, Drebber U, Quaas A, Bruns CJ, Hölscher AH, Von Bergwelt-Baildon MS.

Oncoimmunology. 2018 Nov 2;8(1):e1512458. doi: 10.1080/2162402X.2018.1512458. eCollection 2019.

PMID:
30546950
11.

Documenting metrological traceability as intended by ISO 15189:2012: A consensus statement about the practice of the implementation and auditing of this norm element.

Thelen M, Vanstapel F, Brguljan PM, Gouget B, Boursier G, Barrett E, Kroupis C, Lohmander M, Šprongl L, Vodnik T, Bernabeu-Andreu F, Vukasović I, Sönmez Ç, Linko S, Brugnoni D, Vaubourdolle M, Huisman W, Panteghini M; European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group Accreditation and ISO/CEN standards (WG-A/ISO).

Clin Chem Lab Med. 2019 Mar 26;57(4):459-464. doi: 10.1515/cclm-2018-1212.

12.

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.

Immunity. 2018 Dec 18;49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13.

13.

Author Correction: Jungle Express is a versatile repressor system for tight transcriptional control.

Ruegg TL, Pereira JH, Chen JC, DeGiovanni A, Novichkov P, Mutalik VK, Tomaleri GP, Singer SW, Hillson NJ, Simmons BA, Adams PD, Thelen MP.

Nat Commun. 2018 Oct 30;9(1):4596. doi: 10.1038/s41467-018-07111-2.

14.

Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis.

Cecchinato V, D'Agostino G, Raeli L, Nerviani A, Schiraldi M, Danelon G, Manzo A, Thelen M, Ciurea A, Bianchi ME, Rubartelli A, Pitzalis C, Uguccioni M.

Front Immunol. 2018 Sep 19;9:2118. doi: 10.3389/fimmu.2018.02118. eCollection 2018.

15.

NUMBER: standardized reference intervals in the Netherlands using a 'big data' approach.

den Elzen WPJ, Brouwer N, Thelen MH, Le Cessie S, Haagen IA, Cobbaert CM.

Clin Chem Lab Med. 2018 Dec 19;57(1):42-56. doi: 10.1515/cclm-2018-0462.

16.

Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity.

Schmiesing J, Storch S, Dörfler AC, Schweizer M, Makrypidi-Fraune G, Thelen M, Sylvester M, Gieselmann V, Meyer-Schwesinger C, Koch-Nolte F, Tidow H, Mühlhausen C, Waheed A, Sly WS, Braulke T.

Cell Rep. 2018 Sep 11;24(11):2946-2956. doi: 10.1016/j.celrep.2018.08.014.

17.

Jungle Express is a versatile repressor system for tight transcriptional control.

Ruegg TL, Pereira JH, Chen JC, DeGiovanni A, Novichkov P, Mutalik VK, Tomaleri GP, Singer SW, Hillson NJ, Simmons BA, Adams PD, Thelen MP.

Nat Commun. 2018 Sep 6;9(1):3617. doi: 10.1038/s41467-018-05857-3. Erratum in: Nat Commun. 2018 Oct 30;9(1):4596.

18.

THE MUSCULOSKELETAL READINESS SCREENING TOOL- ATHLETE CONCERN FOR INJURY & PRIOR INJURY ASSOCIATED WITH FUTURE INJURY.

Terry AC, Thelen MD, Crowell M, Goss DL.

Int J Sports Phys Ther. 2018 Aug;13(4):595-604.

19.

CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells-Letter.

Thelen M, Lechner A, Wennhold K, von Bergwelt-Baildon M, Schlößer HA.

Cancer Res. 2018 Sep 1;78(17):5173-5174. doi: 10.1158/0008-5472.CAN-18-0873. Epub 2018 Aug 16. No abstract available.

20.

Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast.

Higgins DA, Young MKM, Tremaine M, Sardi M, Fletcher JM, Agnew M, Liu L, Dickinson Q, Peris D, Wrobel RL, Hittinger CT, Gasch AP, Singer SW, Simmons BA, Landick R, Thelen MP, Sato TK.

Genetics. 2018 Sep;210(1):219-234. doi: 10.1534/genetics.118.301161. Epub 2018 Jul 25.

21.

Leukocyte Tracking Database, a collection of immune cell tracks from intravital 2-photon microscopy videos.

Pizzagalli DU, Farsakoglu Y, Palomino-Segura M, Palladino E, Sintes J, Marangoni F, Mempel TR, Koh WH, Murooka TT, Thelen F, Stein JV, Pozzi G, Thelen M, Krause R, Gonzalez SF.

Sci Data. 2018 Jul 17;5:180129. doi: 10.1038/sdata.2018.129.

22.

Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.

Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ.

Sci Rep. 2018 Jul 3;8(1):10294. doi: 10.1038/s41598-018-28202-6.

23.

Cumulative dose of bevacizumab associates with albuminuria rather than podocyturia in cancer patients.

Lankhorst S, Baelde HJ, Verstijnen JAMC, Ten Tije AJ, Thelen MHM, Danser AHJ, van den Meiracker AH, Kappers MHW.

J Am Soc Hypertens. 2018 Nov;12(11):e1-e7. doi: 10.1016/j.jash.2018.06.005. Epub 2018 Jun 18.

PMID:
29960864
24.

Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease.

Teipel SJ, Metzger CD, Brosseron F, Buerger K, Brueggen K, Catak C, Diesing D, Dobisch L, Fliebach K, Franke C, Heneka MT, Kilimann I, Kofler B, Menne F, Peters O, Polcher A, Priller J, Schneider A, Spottke A, Spruth EJ, Thelen M, Thyrian RJ, Wagner M, Düzel E, Jessen F, Dyrba M; DELCODE study group.

J Alzheimers Dis. 2018;64(3):801-813. doi: 10.3233/JAD-180106.

25.

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.

Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ.

Sci Rep. 2018 May 21;8(1):7907. doi: 10.1038/s41598-018-26347-y. Erratum in: Sci Rep. 2018 Jul 3;8(1):10294.

26.

Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer.

Meder L, Schuldt P, Thelen M, Schmitt A, Dietlein F, Klein S, Borchmann S, Wennhold K, Vlasic I, Oberbeck S, Riedel R, Florin A, Golfmann K, Schlößer HA, Odenthal M, Buettner R, Wolf J, Hallek M, Herling M, von Bergwelt-Baildon M, Reinhardt HC, Ullrich RT.

Cancer Res. 2018 Aug 1;78(15):4270-4281. doi: 10.1158/0008-5472.CAN-17-2176. Epub 2018 May 18.

27.

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells.

Di Lorenzo G, Velho RV, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan TA, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S.

Mol Cell Proteomics. 2018 Aug;17(8):1612-1626. doi: 10.1074/mcp.RA118.000720. Epub 2018 May 17.

28.

Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin.

Marangoni F, Zhang R, Mani V, Thelen M, Ali Akbar NJ, Warner RD, Äijö T, Zappulli V, Martinez GJ, Turka LA, Mempel TR.

J Immunol. 2018 May 15;200(10):3647-3661. doi: 10.4049/jimmunol.1701220. Epub 2018 Apr 16.

29.

Characterization of a chimeric chemokine as a specific ligand for ACKR3.

Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M.

J Leukoc Biol. 2018 Aug;104(2):391-400. doi: 10.1002/JLB.2MA1217-509R. Epub 2018 Mar 30.

30.

Utility of two-view vs. three-view abdominal radiography in canines presenting with acute abdominal signs.

Mavromatis MV, Solano M, Thelen MY.

Vet Radiol Ultrasound. 2018 Jul;59(4):381-386. doi: 10.1111/vru.12611. Epub 2018 Mar 15.

PMID:
29544019
31.

Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation.

Danyukova T, Ariunbat K, Thelen M, Brocke-Ahmadinejad N, Mole SE, Storch S.

Hum Mol Genet. 2018 May 15;27(10):1711-1722. doi: 10.1093/hmg/ddy076.

32.

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2018 Mar 1;128(3):1200-1201. doi: 10.1172/JCI120358. Epub 2018 Mar 1. No abstract available.

33.

Membrane lipid environment: Potential modulation of chemokine receptor function.

Thelen M, Legler DF.

Cytokine. 2018 Sep;109:72-75. doi: 10.1016/j.cyto.2018.02.011. Epub 2018 Feb 9.

PMID:
29433906
34.

New insights in chemokine signaling.

Legler DF, Thelen M.

F1000Res. 2018 Jan 23;7:95. doi: 10.12688/f1000research.13130.1. eCollection 2018. Review.

35.

The quest for equivalence of test results: the pilgrimage of the Dutch Calibration 2.000 program for metrological traceability.

Jansen RTP, Cobbaert CM, Weykamp C, Thelen M.

Clin Chem Lab Med. 2018 Sep 25;56(10):1673-1684. doi: 10.1515/cclm-2017-0796. Review. No abstract available.

36.

Harmonization of accreditation to ISO15189.

Thelen MHM, Huisman W.

Clin Chem Lab Med. 2018 Sep 25;56(10):1637-1643. doi: 10.1515/cclm-2017-0820. No abstract available.

37.

Effects of technique-focused training in conjunction with physical readiness training on Army physical fitness test performance.

Thelen MD, Koppenhaver SL, Gill NW, Shaffer SW.

US Army Med Dep J. 2017 Oct-Dec;(3-17):79-83.

PMID:
29214624
38.

Real time interrater reliability of a novel musculoskeletal readiness screening tool.

Thelen MD, Koppenhaver SL, Allen SE, Bolduc MU, Quan RK, Sidwell AE.

US Army Med Dep J. 2017 Oct-Dec;(3-17):43-51.

PMID:
29214619
39.

ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration.

Puddinu V, Casella S, Radice E, Thelen S, Dirnhofer S, Bertoni F, Thelen M.

Oncotarget. 2017 Jun 29;8(49):85068-85084. doi: 10.18632/oncotarget.18844. eCollection 2017 Oct 17.

40.

Examining tissue composition, whole-bone morphology and mechanical behavior of GorabPrx1 mice tibiae: A mouse model of premature aging.

Yang H, Albiol L, Chan WL, Wulsten D, Seliger A, Thelen M, Thiele T, Spevak L, Boskey A, Kornak U, Checa S, Willie BM.

J Biomech. 2017 Dec 8;65:145-153. doi: 10.1016/j.jbiomech.2017.10.018. Epub 2017 Oct 25.

41.

The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells.

Mazzotti C, Gagliostro V, Bosisio D, Del Prete A, Tiberio L, Thelen M, Sozzani S.

Front Immunol. 2017 Oct 6;8:1233. doi: 10.3389/fimmu.2017.01233. eCollection 2017.

42.

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.

Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E.

Cancer Cell. 2017 Oct 9;32(4):444-459.e7. doi: 10.1016/j.ccell.2017.09.002.

43.

CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2017 Oct 2;127(10):3913. doi: 10.1172/JCI97015. Epub 2017 Aug 28. No abstract available.

44.

Evaluation of a Novel Field Expedient Musculoskeletal Readiness Screening Tool in an Army Basic Training Population.

Hearn D, Rhon D, Goss D, Thelen M.

Mil Med. 2017 Jul;182(7):e1862-e1868. doi: 10.7205/MILMED-D-16-00384.

PMID:
28810983
45.

Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy.

Wennhold K, Thelen M, Schlößer HA, Haustein N, Reuter S, Garcia-Marquez M, Lechner A, Kobold S, Rataj F, Utermöhlen O, Chakupurakal G, Theurich S, Hallek M, Abken H, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M.

Cancer Immunol Res. 2017 Sep;5(9):730-743. doi: 10.1158/2326-6066.CIR-16-0236. Epub 2017 Aug 4.

46.

Chemokines: Chemistry, Biochemistry and Biological Function.

Legler DF, Thelen M.

Chimia (Aarau). 2016 Dec 21;70(12):856-859. doi: 10.2533/chimia.2016.856. Review.

PMID:
28661356
47.

Analytical performance specifications for external quality assessment - definitions and descriptions.

Jones GRD, Albarede S, Kesseler D, MacKenzie F, Mammen J, Pedersen M, Stavelin A, Thelen M, Thomas A, Twomey PJ, Ventura E, Panteghini M; EFLM Task Finish Group – Analytical Performance Specifications for EQAS (TFG-APSEQA).

Clin Chem Lab Med. 2017 Jun 27;55(7):949-955. doi: 10.1515/cclm-2017-0151.

48.

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma.

Lechner A, Schlößer H, Rothschild SI, Thelen M, Reuter S, Zentis P, Shimabukuro-Vornhagen A, Theurich S, Wennhold K, Garcia-Marquez M, Tharun L, Quaas A, Schauss A, Isensee J, Hucho T, Huebbers C, von Bergwelt-Baildon M, Beutner D.

Oncotarget. 2017 Jul 4;8(27):44418-44433. doi: 10.18632/oncotarget.17901.

49.

CXCL12α/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals.

Negro S, Lessi F, Duregotti E, Aretini P, La Ferla M, Franceschi S, Menicagli M, Bergamin E, Radice E, Thelen M, Megighian A, Pirazzini M, Mazzanti CM, Rigoni M, Montecucco C.

EMBO Mol Med. 2017 Aug;9(8):1000-1010. doi: 10.15252/emmm.201607257.

50.

SILAC-Based Comparative Proteomic Analysis of Lysosomes from Mammalian Cells Using LC-MS/MS.

Thelen M, Winter D, Braulke T, Gieselmann V.

Methods Mol Biol. 2017;1594:1-18. doi: 10.1007/978-1-4939-6934-0_1.

PMID:
28456973

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