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A prospective comparison of growth patterns with radiomorphology in 232 lung metastases-basis for patient tailored resection planning?

Issa N, Arfanis E, Hager T, Aigner C, Dietz-Terjung S, Theegarten D, Kühl H, Welter S.

J Thorac Dis. 2019 Jul;11(7):2822-2831. doi: 10.21037/jtd.2019.07.04.


Implementation of an experimental isolated lung perfusion model on surgically resected human lobes.

Slama A, Raber C, Hedderich C, Stockhammer P, Hegedüs B, Koch A, Theegarten D, Ploenes T, Aigner C.

Sci Rep. 2019 Aug 21;9(1):12193. doi: 10.1038/s41598-019-48719-8.


Utility of Anti-DSF70 Antibodies to Predict Connective Tissue Disease in Patients Originally Presenting with Idiopathic Interstitial Pneumonia.

Lyu Y, Boerner E, Theegarten D, Guzman J, Kreuter M, Costabel U, Bonella F.

Respiration. 2019;98(1):29-37. doi: 10.1159/000496483. Epub 2019 Mar 29.


Cytology Versus Histology in the Primary Diagnosis of Lymphoma Located in the Mediastinum.

Plönes T, Mardanzai K, Gafencu D, Viehof J, Hager T, Theegarten D, Dührsen U, Darwiche K, Taube C, Aigner C.

Ann Thorac Surg. 2019 Jul;108(1):244-248. doi: 10.1016/j.athoracsur.2019.02.030. Epub 2019 Mar 20.


Transbronchial cryobiopsy in fibrosing interstitial lung disease: modifications of the procedure lead to risk reduction.

Hagmeyer L, Theegarten D, Wohlschläger J, Hager T, Treml M, Herkenrath SD, Hekmat K, Heldwein M, Randerath WJ.

Thorax. 2019 Jul;74(7):711-714. doi: 10.1136/thoraxjnl-2018-212095. Epub 2019 Mar 9.


Lymph Node Involvement and the Surgical Treatment of Thymic Epithelial and Neuroendocrine Carcinoma.

Cheufou DH, Valdivia D, Puhlvers S, Fels B, Weinreich G, Taube C, Theegarten D, Stuschke M, Schuler M, Hegedus B, Stamatis G, Aigner C.

Ann Thorac Surg. 2019 Jun;107(6):1632-1638. doi: 10.1016/j.athoracsur.2019.01.006. Epub 2019 Feb 2.


Pretreatment metabolic tumour volume in stage IIIA/B non-small-cell lung cancer uncovers differences in effectiveness of definitive radiochemotherapy schedules: analysis of the ESPATUE randomized phase 3 trial.

Guberina M, Eberhardt W, Stuschke M, Gauler T, Aigner C, Schuler M, Stamatis G, Theegarten D, Jentzen W, Herrmann K, Pöttgen C.

Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1439-1447. doi: 10.1007/s00259-019-4270-x. Epub 2019 Feb 1.


Rapid and Highly Sensitive Detection of Therapeutically Relevant Oncogenic Driver Mutations in EBUS-TBNA Specimens From Patients With Lung Adenocarcinoma.

Oezkan F, Herold T, Darwiche K, Eberhardt WEE, Worm K, Christoph DC, Wiesweg M, Freitag L, Schmid KW, Theegarten D, Hager T, Koenig MJ, He K, Taube C, Schuler M, Breitenbuecher F.

Clin Lung Cancer. 2018 Nov;19(6):e879-e884. doi: 10.1016/j.cllc.2018.08.016. Epub 2018 Aug 22.


Exophiala dermatitidis isolates from various sources: using alternative invertebrate host organisms (Caenorhabditis elegans and Galleria mellonella) to determine virulence.

Olsowski M, Hoffmann F, Hain A, Kirchhoff L, Theegarten D, Todt D, Steinmann E, Buer J, Rath PM, Steinmann J.

Sci Rep. 2018 Aug 24;8(1):12747. doi: 10.1038/s41598-018-30909-5.


Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer.

Walter RFH, Rozynek P, Casjens S, Werner R, Mairinger FD, Speel EJM, Zur Hausen A, Meier S, Wohlschlaeger J, Theegarten D, Behrens T, Schmid KW, Brüning T, Johnen G.

PLoS One. 2018 May 31;13(5):e0195716. doi: 10.1371/journal.pone.0195716. eCollection 2018.


Frequencies and expression levels of programmed death ligand 1 (PD-L1) in circulating tumor RNA (ctRNA) in various cancer types.

Ishiba T, Hoffmann AC, Usher J, Elshimali Y, Sturdevant T, Dang M, Jaimes Y, Tyagi R, Gonzales R, Grino M, Pinski JK, Barzi A, Raez LE, Eberhardt WE, Theegarten D, Lenz HJ, Uetake H, Danenberg PV, Danenberg K.

Biochem Biophys Res Commun. 2018 Jun 7;500(3):621-625. doi: 10.1016/j.bbrc.2018.04.120. Epub 2018 Apr 30.


Effectiveness of Robotic Lobectomy-Outcome and Learning Curve in a High Volume Center.

Cheufou DH, Mardanzai K, Ploenes T, Theegarten D, Stamatis G, Kampe S, Aigner C.

Thorac Cardiovasc Surg. 2019 Oct;67(7):573-577. doi: 10.1055/s-0038-1639477. Epub 2018 Apr 6.


Prognostic value of MIB-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score - a multicenter study.

Diebold M, Soltermann A, Hottinger S, Haile SR, Bubendorf L, Komminoth P, Jochum W, Grobholz R, Theegarten D, Berezowska S, Darwiche K, Oezkan F, Kohler M, Franzen DP.

Respir Res. 2017 Dec 16;18(1):210. doi: 10.1186/s12931-017-0693-8.


Pulmonary metastasectomy for sarcoma-Essen experience.

Gafencu DA, Welter S, Cheufou DH, Ploenes T, Stamatis G, Stuschke M, Theegarten D, Taube C, Bauer S, Aigner C.

J Thorac Dis. 2017 Oct;9(Suppl 12):S1278-S1281. doi: 10.21037/jtd.2017.07.47.


Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection.

Seddigh P, Bracht T, Molinier-Frenkel V, Castellano F, Kniemeyer O, Schuster M, Weski J, Hasenberg A, Kraus A, Poschet G, Hager T, Theegarten D, Opitz CA, Brakhage AA, Sitek B, Hasenberg M, Gunzer M.

Mol Cell Proteomics. 2017 Dec;16(12):2184-2198. doi: 10.1074/mcp.RA117.000072. Epub 2017 Sep 26.


Idiopathic pleuroparenchymal fibroelastosis (PPFE) - A case study of a rare entity.

Boerner EB, Costabel U, Wessendorf TE, Theegarten D, Bonella F.

Rev Port Pneumol (2006). 2017 Nov - Dec;23(6):352-355. doi: 10.1016/j.rppnen.2017.06.006. Epub 2017 Aug 3.


Growth patterns of pulmonary metastases: should we adjust resection techniques to primary histology and size?

Welter S, Arfanis E, Christoph D, Hager T, Roesel C, Aigner C, Weinreich G, Theegarten D.

Eur J Cardiothorac Surg. 2017 Jul 1;52(1):39-46. doi: 10.1093/ejcts/ezx063.


Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics.

Großerueschkamp F, Bracht T, Diehl HC, Kuepper C, Ahrens M, Kallenbach-Thieltges A, Mosig A, Eisenacher M, Marcus K, Behrens T, Brüning T, Theegarten D, Sitek B, Gerwert K.

Sci Rep. 2017 Mar 30;7:44829. doi: 10.1038/srep44829.


Erroneous diagnosis of small cell lung cancer based on small biopsies with far-reaching consequences: case report of a typical carcinoid tumor.

Kyritsis I, Krebs B, Kampe S, Theegarten D, Aigner C, Welter S.

J Thorac Dis. 2017 Feb;9(2):E99-E102. doi: 10.21037/jtd.2017.02.35.


High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer.

Wiesweg M, Eberhardt WEE, Reis H, Ting S, Savvidou N, Skiba C, Herold T, Christoph DC, Meiler J, Worm K, Kasper S, Theegarten D, Hense J, Hager T, Darwiche K, Oezkan F, Aigner C, Welter S, Kühl H, Stuschke M, Schmid KW, Schuler M.

J Thorac Oncol. 2017 Jan;12(1):54-64. doi: 10.1016/j.jtho.2016.08.137. Epub 2016 Aug 27.


[Pathology of lung cancer].

Theegarten D, Hager T.

Radiologe. 2016 Sep;56(9):777-85. doi: 10.1007/s00117-016-0154-2. Review. German.


Pulmonary alveolar proteinosis: another autoimmune disease associated with sarcoidosis?

Boerner EB, Costabel U, Wessendorf TE, Theegarten D, Hetzel M, Drent M, Bonella F.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):90-4.


Validation of transbronchial cryobiopsy in interstitial lung disease - interim analysis of a prospective trial and critical review of the literature.

Hagmeyer L, Theegarten D, Treml M, Priegnitz C, Randerath W.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):2-9. Review.


A Single-Institution Analysis of the Surgical Management of Pulmonary Large Cell Neuroendocrine Carcinomas.

Roesel C, Terjung S, Weinreich G, Gauler T, Theegarten D, Stamatis G, Welter S.

Ann Thorac Surg. 2016 May;101(5):1909-14. doi: 10.1016/j.athoracsur.2015.12.009. Epub 2016 Feb 18.


Pulmonary alveolar proteinosis in a cat.

Szatmári V, Teske E, Nikkels PG, Griese M, de Jong PA, Grinwis G, Theegarten D, Veraa S, van Steenbeek FG, Drent M, Bonella F.

BMC Vet Res. 2015 Dec 9;11:302. doi: 10.1186/s12917-015-0613-4.


Initial Host Response to Bacteria in the Murine Lung Differs Between Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.

Preu L, Bischoff M, Veith NT, Rosenbruch M, Theegarten D, Laschke MW, Meier C, Tschernig T.

Inflammation. 2016 Apr;39(2):513-7. doi: 10.1007/s10753-015-0274-2.


GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders.

Griese M, Zarbock R, Costabel U, Hildebrandt J, Theegarten D, Albert M, Thiel A, Schams A, Lange J, Krenke K, Wesselak T, Schön C, Kappler M, Blum H, Krebs S, Jung A, Kröner C, Klein C, Campo I, Luisetti M, Bonella F.

BMC Pulm Med. 2015 Aug 12;15:87. doi: 10.1186/s12890-015-0083-2.


[Coronary atherosclerosis and progression to unstable plaques : Histomorphological and molecular aspects].

Wohlschlaeger J, Bertram S, Theegarten D, Hager T, Baba HA.

Herz. 2015 Sep;40(6):837-44. doi: 10.1007/s00059-015-4341-0. Review. German.


Transbronchial Catheter Aspiration and Transbronchial Needle Aspiration in the Diagnostic Workup of Peripheral Lung Lesions.

Franke KJ, Hein M, Domanski U, Nilius G, Schroeder M, Wohlschlaeger J, Theegarten D.

Lung. 2015 Oct;193(5):767-72. doi: 10.1007/s00408-015-9763-1. Epub 2015 Jul 9.


Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysis.

Walter RF, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J, Mairinger FD.

Oncotarget. 2015 Sep 22;6(28):24690-8. doi: 10.18632/oncotarget.3992.


Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.

Pöttgen C, Stuschke M, Graupner B, Theegarten D, Gauler T, Jendrossek V, Freitag L, Jawad JA, Gkika E, Wohlschlaeger J, Welter S, Hoiczyk M, Schuler M, Stamatis G, Eberhardt W.

BMC Cancer. 2015 May 6;15:363. doi: 10.1186/s12885-015-1389-4.


SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString).

Walter RF, Mairinger FD, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Zarogoulidis K, Schmid KW, Zarogoulidis P, Wohlschlaeger J.

Future Oncol. 2015;11(7):1027-36. doi: 10.2217/fon.15.18.


HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomas.

Reis H, Herold T, Ting S, Worm K, Huber U, Christoph DC, Eberhardt WE, Kostbade K, Kasper S, Stamatis G, Welter S, Darwiche K, Karpf-Wissel R, Theegarten D, Schmid KW, Schuler M, Wiesweg M.

Lung Cancer. 2015 Apr;88(1):34-41. doi: 10.1016/j.lungcan.2015.02.002. Epub 2015 Feb 7.


MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Walter RF, Mairinger FD, Ting S, Vollbrecht C, Mairinger T, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J.

Br J Cancer. 2015 Mar 3;112(5):883-90. doi: 10.1038/bjc.2015.27. Epub 2015 Feb 10.


The role of transbronchial cryobiopsy and surgical lung biopsy in the diagnostic algorithm of interstitial lung disease.

Hagmeyer L, Theegarten D, Wohlschläger J, Treml M, Matthes S, Priegnitz C, Randerath WJ.

Clin Respir J. 2016 Sep;10(5):589-95. doi: 10.1111/crj.12261. Epub 2015 Mar 3.


Marker-free automated histopathological annotation of lung tumour subtypes by FTIR imaging.

Großerueschkamp F, Kallenbach-Thieltges A, Behrens T, Brüning T, Altmayer M, Stamatis G, Theegarten D, Gerwert K.

Analyst. 2015 Apr 7;140(7):2114-20. doi: 10.1039/c4an01978d.


Efficient utilization of EBUS-TBNA samples for both diagnosis and molecular analyses.

Oezkan F, Khan A, Zarogoulidis P, Hohenforst-Schmidt W, Theegarten D, Yasufuku K, Nakajima T, Freitag L, Darwiche K.

Onco Targets Ther. 2014 Nov 10;7:2061-5. doi: 10.2147/OTT.S72974. eCollection 2014.


[Infectious pulmonary diseases].

Hager T, Reis H, Theegarten D.

Pathologe. 2014 Nov;35(6):606-11. doi: 10.1007/s00292-014-1924-0. Review. German.


Gene Expression Analysis of the 26S Proteasome Subunit PSMB4 Reveals Significant Upregulation, Different Expression and Association with Proliferation in Human Pulmonary Neuroendocrine Tumours.

Mairinger FD, Walter RF, Theegarten D, Hager T, Vollbrecht C, Christoph DC, Worm K, Ting S, Werner R, Stamatis G, Mairinger T, Baba H, Zarogoulidis K, Huang H, Li Q, Tsakiridis K, Zarogoulidis P, Schmid KW, Wohlschlaeger J.

J Cancer. 2014 Aug 1;5(8):646-54. doi: 10.7150/jca.9955. eCollection 2014.


Surgery of primary lung cancer with oligometastatic m1b synchronous single brain metastasis: analysis of 37 cases.

Cheufou DH, Welter S, Chalvatzoulis E, Christof D, Theegarten D, Stamatis G.

Thorac Cardiovasc Surg. 2014 Oct;62(7):612-5. doi: 10.1055/s-0034-1377060. Epub 2014 Aug 19.


Mdm2 protein expression is strongly associated with survival in malignant pleural mesothelioma.

Mairinger FD, Walter RF, Ting S, Vollbrecht C, Kollmeier J, Griff S, Hager T, Mairinger T, Christoph DC, Theegarten D, Schmid KW, Wohlschlaeger J.

Future Oncol. 2014 May;10(6):995-1005. doi: 10.2217/fon.13.261.


Management of a chest-wall soft-tissue tumor caused by an infection with the larval tapeworm pathogen Taenia crassiceps.

Roesel C, Welter S, Stamatis G, Theegarten D, Tappe D.

Am J Trop Med Hyg. 2014 Sep;91(3):541-3. doi: 10.4269/ajtmh.14-0185. Epub 2014 Jun 9.


Different micro-RNA expression profiles distinguish subtypes of neuroendocrine tumors of the lung: results of a profiling study.

Mairinger FD, Ting S, Werner R, Walter RF, Hager T, Vollbrecht C, Christoph D, Worm K, Mairinger T, Sheu-Grabellus SY, Theegarten D, Schmid KW, Wohlschlaeger J.

Mod Pathol. 2014 Dec;27(12):1632-40. doi: 10.1038/modpathol.2014.74. Epub 2014 May 30.


"One-stop shop" spectral imaging for rapid on-site diagnosis of lung cancer: a future concept in nano-oncology.

Darwiche K, Zarogoulidis P, Krauss L, Oezkan F, Walter RF, Werner R, Theegarten D, Sakkas L, Sakkas A, Hohenforst-Scmidt W, Zarogoulidis K, Freitag L.

Int J Nanomedicine. 2013;8:4533-42. doi: 10.2147/IJN.S54418. Epub 2013 Nov 22.


Experimental respiratory syncytial virus infection of human peribronchial gland cells in vitro.

Anhenn O, Stamatis G, Theegarten D.

Ultrastruct Pathol. 2013 Oct;37(5):312-7. doi: 10.3109/01913123.2013.810685.


Assessment of SHOX2 methylation in EBUS-TBNA specimen improves accuracy in lung cancer staging.

Darwiche K, Zarogoulidis P, Baehner K, Welter S, Tetzner R, Wohlschlaeger J, Theegarten D, Nakajima T, Freitag L.

Ann Oncol. 2013 Nov;24(11):2866-70. doi: 10.1093/annonc/mdt365. Epub 2013 Sep 11.


10-year long-term survival (LTS) of induction chemotherapy with three cycles cisplatin/paclitaxel followed by concurrent chemoradiation cisplatin/etoposide/45 Gy (1.5 Gy bid) plus surgery in locally advanced non-small-cell lung cancer (NSCLC)-a multicenter phase-II trial (CISTAXOL).

Eberhardt WE, Gauler TC, Lepechoux C, Stamatis G, Bildat S, Krbek T, Welter S, Grunenwald D, Fischer B, Rodrigo Hde L, Theegarten D, Le Chevalier T, Seeber S, Stuschke M, Poettgen C.

Lung Cancer. 2013 Oct;82(1):83-9. doi: 10.1016/j.lungcan.2013.06.007. Epub 2013 Aug 16.


Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.

Wiesweg M, Ting S, Reis H, Worm K, Kasper S, Tewes M, Welt A, Richly H, Meiler J, Bauer S, Hense J, Gauler TC, Köhler J, Eberhardt WE, Darwiche K, Freitag L, Stamatis G, Breitenbücher F, Wohlschlaeger J, Theegarten D, Derks C, Cortes-Incio D, Linden G, Skottky S, Lütkes P, Dechêne A, Paul A, Markus P, Schmid KW, Schuler M.

Eur J Cancer. 2013 Oct;49(15):3076-82. doi: 10.1016/j.ejca.2013.06.014. Epub 2013 Jul 19.


Evaluation of a novel endobronchial ultrasound-guided lymph node forceps in enlarged mediastinal lymph nodes.

Darwiche K, Freitag L, Nair A, Neumann C, Karpf-Wissel R, Welter S, Wohlschlaeger J, Theegarten D.

Respiration. 2013;86(3):229-36. doi: 10.1159/000350867. Epub 2013 Jul 17.

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