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Items: 20

1.

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.

Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, Brodsky JL, Thathiah A, Shorter J, Donnelly CJ.

Neuron. 2019 Apr 17;102(2):321-338.e8. doi: 10.1016/j.neuron.2019.01.048. Epub 2019 Feb 27.

PMID:
30826182
2.

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.

Welty S, Teng Y, Liang Z, Zhao W, Sanders LH, Greenamyre JT, Rubio ME, Thathiah A, Kodali R, Wetzel R, Levine AS, Lan L.

J Biol Chem. 2018 Jan 26;293(4):1353-1362. doi: 10.1074/jbc.M117.808402. Epub 2017 Dec 7.

3.

The role of GPCRs in neurodegenerative diseases: avenues for therapeutic intervention.

Huang Y, Todd N, Thathiah A.

Curr Opin Pharmacol. 2017 Feb;32:96-110. doi: 10.1016/j.coph.2017.02.001. Epub 2017 Mar 10. Review.

PMID:
28288370
4.

Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.

Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B.

Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0.

5.

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.

Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A.

Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492.

PMID:
26468326
6.

Regulation of neuronal communication by G protein-coupled receptors.

Huang Y, Thathiah A.

FEBS Lett. 2015 Jun 22;589(14):1607-19. doi: 10.1016/j.febslet.2015.05.007. Epub 2015 May 14. Review.

7.

Regulation of amyloid precursor protein processing by serotonin signaling.

Pimenova AA, Thathiah A, De Strooper B, Tesseur I.

PLoS One. 2014 Jan 21;9(1):e87014. doi: 10.1371/journal.pone.0087014. eCollection 2014.

8.

Alteration of the microRNA network during the progression of Alzheimer's disease.

Lau P, Bossers K, Janky R, Salta E, Frigerio CS, Barbash S, Rothman R, Sierksma AS, Thathiah A, Greenberg D, Papadopoulou AS, Achsel T, Ayoubi T, Soreq H, Verhaagen J, Swaab DF, Aerts S, De Strooper B.

EMBO Mol Med. 2013 Oct;5(10):1613-34. doi: 10.1002/emmm.201201974. Epub 2013 Sep 9.

9.

β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Thathiah A, Horré K, Snellinx A, Vandewyer E, Huang Y, Ciesielska M, De Kloe G, Munck S, De Strooper B.

Nat Med. 2013 Jan;19(1):43-9. doi: 10.1038/nm.3023. Epub 2012 Dec 2.

PMID:
23202293
10.

The role of G protein-coupled receptors in the pathology of Alzheimer's disease.

Thathiah A, De Strooper B.

Nat Rev Neurosci. 2011 Feb;12(2):73-87. doi: 10.1038/nrn2977. Review.

PMID:
21248787
11.

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.

Jorissen E, Prox J, Bernreuther C, Weber S, Schwanbeck R, Serneels L, Snellinx A, Craessaerts K, Thathiah A, Tesseur I, Bartsch U, Weskamp G, Blobel CP, Glatzel M, De Strooper B, Saftig P.

J Neurosci. 2010 Apr 7;30(14):4833-44. doi: 10.1523/JNEUROSCI.5221-09.2010.

12.

G protein-coupled receptors, cholinergic dysfunction, and Abeta toxicity in Alzheimer's disease.

Thathiah A, De Strooper B.

Sci Signal. 2009 Oct 20;2(93):re8. doi: 10.1126/scisignal.293re8. Review.

PMID:
19843960
13.

The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horré K, Vanbrabant M, Coun F, Baekelandt V, Delacourte A, Fischer DF, Pollet D, De Strooper B, Merchiers P.

Science. 2009 Feb 13;323(5916):946-51. doi: 10.1126/science.1160649.

14.

ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.

Tousseyn T, Thathiah A, Jorissen E, Raemaekers T, Konietzko U, Reiss K, Maes E, Snellinx A, Serneels L, Nyabi O, Annaert W, Saftig P, Hartmann D, De Strooper B.

J Biol Chem. 2009 Apr 24;284(17):11738-47. doi: 10.1074/jbc.M805894200. Epub 2009 Feb 11.

15.

Tumor necrosis factor alpha stimulates MUC1 synthesis and ectodomain release in a human uterine epithelial cell line.

Thathiah A, Brayman M, Dharmaraj N, Julian JJ, Lagow EL, Carson DD.

Endocrinology. 2004 Sep;145(9):4192-203. Epub 2004 May 13.

PMID:
15142990
16.

MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17.

Thathiah A, Carson DD.

Biochem J. 2004 Aug 15;382(Pt 1):363-73.

17.

MUC1: a multifunctional cell surface component of reproductive tissue epithelia.

Brayman M, Thathiah A, Carson DD.

Reprod Biol Endocrinol. 2004 Jan 7;2:4. Review.

18.

Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding.

Thathiah A, Blobel CP, Carson DD.

J Biol Chem. 2003 Jan 31;278(5):3386-94. Epub 2002 Nov 18.

19.

Changes in gene expression during the early to mid-luteal (receptive phase) transition in human endometrium detected by high-density microarray screening.

Carson DD, Lagow E, Thathiah A, Al-Shami R, Farach-Carson MC, Vernon M, Yuan L, Fritz MA, Lessey B.

Mol Hum Reprod. 2002 Sep;8(9):871-9.

PMID:
12200466
20.

Mucins and blastocyst attachment.

Thathiah A, Carson DD.

Rev Endocr Metab Disord. 2002 May;3(2):87-96. Review. No abstract available.

PMID:
12007285

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