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Items: 23

1.

TRIM24 as an independent prognostic biomarker for prostate cancer.

Offermann A, Roth D, Hupe MC, Hohensteiner S, Becker F, Joerg V, Carlsson J, Kuempers C, Ribbat-Idel J, Tharun L, Sailer V, Kirfel J, Svensson M, Andren O, Lubczyk V, Kuefer R, Merseburger AS, Perner S.

Urol Oncol. 2019 Jun 7. pii: S1078-1439(19)30192-9. doi: 10.1016/j.urolonc.2019.05.006. [Epub ahead of print]

PMID:
31178279
2.

[Tumor-induced osteomalacia caused by an FGF23-secreting myopericytoma : Case report and literature review].

Muro Bushart N, Tharun L, Oheim R, Paech A, Kiene J.

Orthopade. 2019 Apr 1. doi: 10.1007/s00132-019-03719-4. [Epub ahead of print] Review. German.

PMID:
30937490
3.

The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression.

Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B, Reinhardt HC.

Cell Rep. 2018 Oct 23;25(4):1027-1039.e6. doi: 10.1016/j.celrep.2018.09.079.

4.

Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer.

Golfmann K, Meder L, Koker M, Volz C, Borchmann S, Tharun L, Dietlein F, Malchers F, Florin A, Büttner R, Rosen N, Rodrik-Outmezguine V, Hallek M, Ullrich RT.

Oncogene. 2018 Oct;37(42):5682-5693. doi: 10.1038/s41388-018-0380-3. Epub 2018 Jul 3.

PMID:
29970903
5.

Codon-specific translation reprogramming promotes resistance to targeted therapy.

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquière B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Büttner R, Marine JC, Chariot A, Close P.

Nature. 2018 Jun;558(7711):605-609. doi: 10.1038/s41586-018-0243-7. Epub 2018 Jun 20.

PMID:
29925953
6.

The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.

Duong HQ, Nemazanyy I, Rambow F, Tang SC, Delaunay S, Tharun L, Florin A, Büttner R, Vandaele D, Close P, Marine JC, Shostak K, Chariot A.

Cancer Res. 2018 Aug 15;78(16):4533-4548. doi: 10.1158/0008-5472.CAN-17-3149. Epub 2018 Jun 18.

PMID:
29915160
7.

Therapy susceptible germline-related BRCA 1-mutation in a case of metastasized mixed adeno-neuroendocrine carcinoma (MANEC) of the small bowel.

Quaas A, Waldschmidt D, Alakus H, Zander T, Heydt C, Goeser T, Daheim M, Kasper P, Plum P, Bruns C, Brunn A, Roth W, Hartmann N, Bunck A, Schmidt M, Göbel H, Tharun L, Buettner R, Merkelbach-Bruse S.

BMC Gastroenterol. 2018 May 31;18(1):75. doi: 10.1186/s12876-018-0803-1.

8.

High protein and mRNA expression levels of TUBB3 (class III ß-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas.

Loeser H, Schallenberg S, von Winterfeld M, Tharun L, Alakus H, Hölscher A, Bollschweiler E, Buettner R, Zander T, Quaas A.

Oncotarget. 2017 Dec 11;8(70):115179-115189. doi: 10.18632/oncotarget.23112. eCollection 2017 Dec 29.

9.

Surgical Implications for Diagnosis and Treatment of Intestinal Aspergillosis in Pediatric Patients with ALL.

Fischer J, Simon T, Hamprecht A, Hos N, Möricke A, Cernaianu G, Tharun L, Gruhn B, Plum G, Dübbers M.

Eur J Pediatr Surg. 2018 Dec;28(6):477-483. doi: 10.1055/s-0037-1607194. Epub 2017 Sep 25.

PMID:
28946164
10.

First case report of a curative wedge resection in epithelial-myoepithelial carcinoma of the lung.

Hagmeyer L, Tharun L, Schäfer SC, Hekmat K, Büttner R, Randerath W.

Gen Thorac Cardiovasc Surg. 2017 Sep;65(9):535-538. doi: 10.1007/s11748-017-0796-7. Epub 2017 Jun 26.

PMID:
28653299
11.

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma.

Lechner A, Schlößer H, Rothschild SI, Thelen M, Reuter S, Zentis P, Shimabukuro-Vornhagen A, Theurich S, Wennhold K, Garcia-Marquez M, Tharun L, Quaas A, Schauss A, Isensee J, Hucho T, Huebbers C, von Bergwelt-Baildon M, Beutner D.

Oncotarget. 2017 Jul 4;8(27):44418-44433. doi: 10.18632/oncotarget.17901.

12.

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases.

Koelsche C, Schrimpf D, Tharun L, Roth E, Sturm D, Jones DTW, Renker EK, Sill M, Baude A, Sahm F, Capper D, Bewerunge-Hudler M, Hartmann W, Kulozik AE, Petersen I, Flucke U, Schreuder HWB, Büttner R, Weber MA, Schirmacher P, Plass C, Pfister SM, von Deimling A, Mechtersheimer G.

Clin Sarcoma Res. 2017 May 4;7:9. doi: 10.1186/s13569-017-0075-5. eCollection 2017.

13.

Correction: Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A.

J Exp Med. 2017 Apr 3;214(4):1199. doi: 10.1084/jem.2014228803082017c. Epub 2017 Mar 10. No abstract available.

14.

Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.

Delaunay S, Rapino F, Tharun L, Zhou Z, Heukamp L, Termathe M, Shostak K, Klevernic I, Florin A, Desmecht H, Desmet CJ, Nguyen L, Leidel SA, Willis AE, Büttner R, Chariot A, Close P.

J Exp Med. 2016 Oct 17;213(11):2503-2523. Epub 2016 Oct 10.

15.

STAT3/IRF1 Pathway Activation Sensitizes Cervical Cancer Cells to Chemotherapeutic Drugs.

Walch-Rückheim B, Pahne-Zeppenfeld J, Fischbach J, Wickenhauser C, Horn LC, Tharun L, Büttner R, Mallmann P, Stern P, Kim YJ, Bohle RM, Rübe C, Ströder R, Juhasz-Böss I, Solomayer EF, Smola S.

Cancer Res. 2016 Jul 1;76(13):3872-83. doi: 10.1158/0008-5472.CAN-14-1306. Epub 2016 May 23.

16.

Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A.

J Exp Med. 2015 Nov 16;212(12):2057-75. doi: 10.1084/jem.20142288. Epub 2015 Nov 2. Erratum in: J Exp Med. 2017 Apr 3;214(4):1199.

17.

Criteria Used in Clinical Practice to Guide Immunosuppressive Treatment in Patients with Primary Sclerosing Cholangitis.

Schulze K, Weismüller TJ, Bubenheim M, Huebener P, Zenouzi R, Lenzen H, Rupp C, Gotthardt D, de Leuw P, Teufel A, Zimmer V, Reiter FP, Rust C, Tharun L, Quaas A, Weidemann SA, Lammert F, Sarrazin C, Manns MP, Lohse AW, Schramm C; German PSC Study Group.

PLoS One. 2015 Oct 21;10(10):e0140525. doi: 10.1371/journal.pone.0140525. eCollection 2015.

18.

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein F, Kalb B, Jokic M, Noll EM, Strong A, Tharun L, Ozretić L, Künstlinger H, Kambartel K, Randerath WJ, Jüngst C, Schmitt A, Torgovnick A, Richters A, Rauh D, Siedek F, Persigehl T, Mauch C, Bartkova J, Bradley A, Sprick MR, Trumpp A, Rad R, Saur D, Bartek J, Wolf J, Büttner R, Thomas RK, Reinhardt HC.

Cell. 2015 Jul 2;162(1):146-59. doi: 10.1016/j.cell.2015.05.053. Erratum in: Cell. 2015 Aug 27;162(5):1169.

19.

Frequency of TERT promoter mutations in primary tumors of the liver.

Quaas A, Oldopp T, Tharun L, Klingenfeld C, Krech T, Sauter G, Grob TJ.

Virchows Arch. 2014 Dec;465(6):673-7. doi: 10.1007/s00428-014-1658-7. Epub 2014 Sep 30.

PMID:
25267585
20.

Prognostic impact of perineural, blood and lymph vessel invasion for esophageal cancer.

Tachezy M, Tiebel AK, Gebauer F, Kutup A, Tharun L, Pantel K, Izbicki JR, Vashist YK.

Histol Histopathol. 2014 Nov;29(11):1467-75. doi: 10.14670/HH-29.1467. Epub 2014 May 12.

PMID:
24819775
21.

Morphological study of synovial changes in two-stage reconstructions of the infected hip and knee arthroplasties.

Gontarewicz A, Niggemeyer O, Tharun L, Grancicova L, Rüther W, Zustin J.

BMJ Open. 2012 Aug 13;2(4). pii: e001467. doi: 10.1136/bmjopen-2012-001467. Print 2012.

22.

Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer.

Choschzick M, Lebeau A, Marx AH, Tharun L, Terracciano L, Heilenkötter U, Jaenicke F, Bokemeyer C, Simon R, Sauter G, Schwarz J.

Hum Pathol. 2010 Mar;41(3):358-65. doi: 10.1016/j.humpath.2009.08.008. Epub 2009 Nov 6.

PMID:
19896697
23.

HER-2 amplification is highly homogenous in gastric cancer.

Marx AH, Tharun L, Muth J, Dancau AM, Simon R, Yekebas E, Kaifi JT, Mirlacher M, Brümmendorf TH, Bokemeyer C, Izbicki JR, Sauter G.

Hum Pathol. 2009 Jun;40(6):769-77. doi: 10.1016/j.humpath.2008.11.014. Epub 2009 Mar 9.

PMID:
19269014

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