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Items: 19

1.

Cervical mucus sialic acid content determines the progression of thawed ram sperm through the cervix.

Richardson L, Hanrahan JP, Tharmalingam T, Carrington S, Lonergan P, Evans ACO, Fair S.

Reproduction. 2019 Jan 1. pii: REP-18-0547.R1. doi: 10.1530/REP-18-0547. [Epub ahead of print]

PMID:
30608906
2.

Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line.

Tharmalingam T, Barkhordarian H, Tejeda N, Daris K, Yaghmour S, Yam P, Lu F, Goudar C, Munro T, Stevens J.

Biotechnol Prog. 2018 May;34(3):613-623. doi: 10.1002/btpr.2666.

3.

Siglec expression on the surface of human, bull and ram sperm.

Alkhodair K, Almhanna H, McGetrick J, Gedair S, Gallagher ME, Fernandez-Fuertes B, Tharmalingam T, Larsen PB, Fitzpatrick E, Lonergan P, Evans ACO, Carrington SD, Reid CJ.

Reproduction. 2018 Apr;155(4):361-371. doi: 10.1530/REP-17-0475.

PMID:
29581386
4.

In vitro generation of polysialylated cervical mucins by bacterial polysialyltransferases to counteract cytotoxicity of extracellular histones.

Galuska SP, Galuska CE, Tharmalingam T, Zlatina K, Prem G, Husejnov FCO, Rudd PM, Vann WF, Reid C, Vionnet J, Gallagher ME, Carrington FA, Hassett SL, Carrington SD.

FEBS J. 2017 Jun;284(11):1688-1699. doi: 10.1111/febs.14073. Epub 2017 Apr 26.

5.

A framework for real-time glycosylation monitoring (RT-GM) in mammalian cell culture.

Tharmalingam T, Wu CH, Callahan S, T Goudar C.

Biotechnol Bioeng. 2015 Jun;112(6):1146-54. doi: 10.1002/bit.25520. Epub 2015 Apr 17.

PMID:
25545171
6.

Evaluating the impact of high Pluronic® F68 concentrations on antibody producing CHO cell lines.

Tharmalingam T, Goudar CT.

Biotechnol Bioeng. 2015 Apr;112(4):832-7. doi: 10.1002/bit.25491. Epub 2014 Dec 18.

PMID:
25384465
7.

Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures.

Du Z, Treiber D, McCarter JD, Fomina-Yadlin D, Saleem RA, McCoy RE, Zhang Y, Tharmalingam T, Leith M, Follstad BD, Dell B, Grisim B, Zupke C, Heath C, Morris AE, Reddy P.

Biotechnol Bioeng. 2015 Jan;112(1):141-55. doi: 10.1002/bit.25332. Epub 2014 Sep 2.

8.

A HPLC-based glycoanalytical protocol allows the use of natural O-glycans derived from glycoproteins as substrates for glycosidase discovery from microbial culture.

Liu L, Tharmalingam T, Maischberger E, Albrecht S, Gallagher ME, Miranda-Casoluengo R, Meijer WG, Rudd PM, Irwin JA.

Glycoconj J. 2013 Nov;30(8):791-800. doi: 10.1007/s10719-013-9483-9. Epub 2013 Jun 25.

PMID:
23793847
9.

Molecular aspects of mucin biosynthesis and mucus formation in the bovine cervix during the periestrous period.

Pluta K, McGettigan PA, Reid CJ, Browne JA, Irwin JA, Tharmalingam T, Corfield A, Baird A, Loftus BJ, Evans AC, Carrington SD.

Physiol Genomics. 2012 Dec 18;44(24):1165-78. doi: 10.1152/physiolgenomics.00088.2012. Epub 2012 Oct 23.

PMID:
23092952
10.

Strategies for the profiling, characterisation and detailed structural analysis of N-linked oligosaccharides.

Tharmalingam T, Adamczyk B, Doherty MA, Royle L, Rudd PM.

Glycoconj J. 2013 Feb;30(2):137-46. doi: 10.1007/s10719-012-9443-9. Epub 2012 Aug 26. Review.

PMID:
22922975
11.

Glycans as cancer biomarkers.

Adamczyk B, Tharmalingam T, Rudd PM.

Biochim Biophys Acta. 2012 Sep;1820(9):1347-53. doi: 10.1016/j.bbagen.2011.12.001. Epub 2011 Dec 9. Review.

PMID:
22178561
12.

Inhibitor of kappa B epsilon (IκBε) is a non-redundant regulator of c-Rel-dependent gene expression in murine T and B cells.

Clark JM, Aleksiyadis K, Martin A, McNamee K, Tharmalingam T, Williams RO, Mémet S, Cope AP.

PLoS One. 2011;6(9):e24504. doi: 10.1371/journal.pone.0024504. Epub 2011 Sep 6.

13.

Enhanced production of human recombinant proteins from CHO cells grown to high densities in macroporous microcarriers.

Tharmalingam T, Sunley K, Spearman M, Butler M.

Mol Biotechnol. 2011 Nov;49(3):263-76. doi: 10.1007/s12033-011-9401-y.

PMID:
21472499
14.

Discovering new clinical markers in the field of glycomics.

Telford JE, Doherty MA, Tharmalingam T, Rudd PM.

Biochem Soc Trans. 2011 Jan;39(1):327-30. doi: 10.1042/BST0390327.

PMID:
21265797
15.

High productivity of human recombinant beta-interferon from a low-temperature perfusion culture.

Rodriguez J, Spearman M, Tharmalingam T, Sunley K, Lodewyks C, Huzel N, Butler M.

J Biotechnol. 2010 Dec;150(4):509-18. doi: 10.1016/j.jbiotec.2010.09.959. Epub 2010 Oct 8.

PMID:
20933553
16.

Platform technology to identify potential disease markers and establish heritability and environmental determinants of the human serum N-glycome.

Tharmalingam T, Mariño K, Rudd PM.

Carbohydr Res. 2010 Jul 2;345(10):1280-2. doi: 10.1016/j.carres.2010.04.012. Epub 2010 Apr 18. Review.

PMID:
20447618
17.

CHO cells adapted to hypothermic growth produce high yields of recombinant beta-interferon.

Sunley K, Tharmalingam T, Butler M.

Biotechnol Prog. 2008 Jul-Aug;24(4):898-906. doi: 10.1002/btpr.9.

PMID:
19194899
18.

High yields of monomeric recombinant beta-interferon from macroporous microcarrier cultures under hypothermic conditions.

Tharmalingam T, Sunley K, Butler M.

Biotechnol Prog. 2008 Jul-Aug;24(4):832-8. doi: 10.1002/btpr.8.

PMID:
19194894
19.

Pluronic enhances the robustness and reduces the cell attachment of mammalian cells.

Tharmalingam T, Ghebeh H, Wuerz T, Butler M.

Mol Biotechnol. 2008 Jun;39(2):167-77. doi: 10.1007/s12033-008-9045-8.

PMID:
18327558

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