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Items: 17


The Anti-virulence Efficacy of 4-(1,3-Dimethyl-2,3-Dihydro-1H-Benzimidazol-2-yl)Phenol Against Methicillin-Resistant Staphylococcus aureus.

Tharmalingam N, Khader R, Fuchs BB, Mylonakis E.

Front Microbiol. 2019 Jul 17;10:1557. doi: 10.3389/fmicb.2019.01557. eCollection 2019.


Auranofin is an effective agent against clinical isolates of Staphylococcus aureus.

Tharmalingam N, Ribeiro NQ, da Silva DL, Naik MT, Cruz LI, Kim W, Shen S, Dos Santos JD, Ezikovich K, D'Agata EM, Mylonakis E, Fuchs BB.

Future Med Chem. 2019 Jun;11(12):1417-1425. doi: 10.4155/fmc-2018-0544. Epub 2019 Jul 12.


Auranofin Releasing Antibacterial and Antibiofilm Polyurethane Intravascular Catheter Coatings.

Liu H, Shukla S, Vera-González N, Tharmalingam N, Mylonakis E, Fuchs BB, Shukla A.

Front Cell Infect Microbiol. 2019 Feb 28;9:37. doi: 10.3389/fcimb.2019.00037. eCollection 2019.


Anti-Candida albicans Activity of Thiazolylhydrazone Derivatives in Invertebrate and Murine Models.

Cruz LIB, Lopes LFF, de Camargo Ribeiro F, de Sá NP, Lino CI, Tharmalingam N, de Oliveira RB, Rosa CA, Mylonakis E, Fuchs BB, Johann S.

J Fungi (Basel). 2018 Dec 12;4(4). pii: E134. doi: 10.3390/jof4040134.


Vulnerability of long-term care facility residents to Clostridium difficile infection due to microbiome disruptions.

Fuchs BB, Tharmalingam N, Mylonakis E.

Future Microbiol. 2018 Oct;13:1537-1547. doi: 10.2217/fmb-2018-0157. Epub 2018 Oct 12. Review.


Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori.

Tharmalingam N, Port J, Castillo D, Mylonakis E.

Sci Rep. 2018 Feb 27;8(1):3701. doi: 10.1038/s41598-018-22037-x.


Antibacterial Properties of Four Novel Hit Compounds from a Methicillin-Resistant Staphylococcus aureus-Caenorhabditis elegans High-Throughput Screen.

Tharmalingam N, Rajmuthiah R, Kim W, Fuchs BB, Jeyamani E, Kelso MJ, Mylonakis E.

Microb Drug Resist. 2018 Jun;24(5):666-674. doi: 10.1089/mdr.2017.0250. Epub 2018 Feb 20.


Antimicrobial activity of 1,3,4-oxadiazole derivatives against planktonic cells and biofilm of Staphylococcus aureus.

Zheng Z, Liu Q, Kim W, Tharmalingam N, Fuchs BB, Mylonakis E.

Future Med Chem. 2018 Feb;10(3):283-296. doi: 10.4155/fmc-2017-0159. Epub 2018 Jan 15.


Regulatory Effects of Black Rice Extract on Helicobacter pylori Infection-Induced Apoptosis.

Kim SH, Lee MH, Park M, Woo HJ, Kim YS, Tharmalingam N, Seo WD, Kim JB.

Mol Nutr Food Res. 2018 Feb;62(3). doi: 10.1002/mnfr.201700586. Epub 2017 Dec 14.


Activity of a novel protonophore against methicillin-resistant Staphylococcus aureus.

Tharmalingam N, Jayamani E, Rajamuthiah R, Castillo D, Fuchs BB, Kelso MJ, Mylonakis E.

Future Med Chem. 2017 Aug;9(12):1401-1411. doi: 10.4155/fmc-2017-0047. Epub 2017 Aug 3.


Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds.

Jayamani E, Tharmalingam N, Rajamuthiah R, Coleman JJ, Kim W, Okoli I, Hernandez AM, Lee K, Nau GJ, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00310-17. doi: 10.1128/AAC.00310-17. Print 2017 Sep.


Synergistic Efficacy of Aedes aegypti Antimicrobial Peptide Cecropin A2 and Tetracycline against Pseudomonas aeruginosa.

Zheng Z, Tharmalingam N, Liu Q, Jayamani E, Kim W, Fuchs BB, Zhang R, Vilcinskas A, Mylonakis E.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00686-17. doi: 10.1128/AAC.00686-17. Print 2017 Jul.


Repurposing niclosamide as a versatile antimicrobial surface coating against device-associated, hospital-acquired bacterial infections.

Gwisai T, Hollingsworth NR, Cowles S, Tharmalingam N, Mylonakis E, Fuchs BB, Shukla A.

Biomed Mater. 2017 Jul 12;12(4):045010. doi: 10.1088/1748-605X/aa7105.


Menadione induces G2/M arrest in gastric cancer cells by down-regulation of CDC25C and proteasome mediated degradation of CDK1 and cyclin B1.

Lee MH, Cho Y, Kim DH, Woo HJ, Yang JY, Kwon HJ, Yeon MJ, Park M, Kim SH, Moon C, Tharmalingam N, Kim TU, Kim JB.

Am J Transl Res. 2016 Dec 15;8(12):5246-5255. eCollection 2016.


Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes β-catenin mediated oncogenesis and IL-8 secretion in vitro.

Tharmalingam N, Park M, Lee MH, Woo HJ, Kim HW, Yang JY, Rhee KJ, Kim JB.

Am J Transl Res. 2016 Feb 15;8(2):885-98. eCollection 2016.


Inhibitory effect of piperine on Helicobacter pylori growth and adhesion to gastric adenocarcinoma cells.

Tharmalingam N, Kim SH, Park M, Woo HJ, Kim HW, Yang JY, Rhee KJ, Kim JB.

Infect Agent Cancer. 2014 Dec 16;9(1):43. doi: 10.1186/1750-9378-9-43. eCollection 2014.


Inhibitory effects of anthocyanins on secretion of Helicobacter pylori CagA and VacA toxins.

Kim SH, Park M, Woo H, Tharmalingam N, Lee G, Rhee KJ, Eom YB, Han SI, Seo WD, Kim JB.

Int J Med Sci. 2012;9(10):838-42. doi: 10.7150/ijms.5094. Epub 2012 Nov 1.

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