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Items: 1 to 50 of 127

1.

Brief and extended abstinence from chronic oral methylphenidate treatment produces reversible behavioral and physiological effects.

Kalinowski L, Connor C, Somanesan R, Carias E, Richer K, Smith L, Martin C, Mackintosh M, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK.

Dev Psychobiol. 2019 Aug 27. doi: 10.1002/dev.21902. [Epub ahead of print]

PMID:
31456229
2.

Roux-en-Y gastric bypass in rat reduces mu-opioid receptor levels in brain regions associated with stress and energy regulation.

McGregor M, Hamilton J, Hajnal A, Thanos PK.

PLoS One. 2019 Jun 20;14(6):e0218680. doi: 10.1371/journal.pone.0218680. eCollection 2019.

3.

Chronic aerobic exercise: Lack of effect on brain CB1 receptor levels in adult rats.

Swenson S, Hamilton J, Robison L, Thanos PK.

Life Sci. 2019 Aug 1;230:84-88. doi: 10.1016/j.lfs.2019.05.058. Epub 2019 May 22.

PMID:
31128137
4.

Understanding the Scientific Basis of Post-traumatic Stress Disorder (PTSD): Precision Behavioral Management Overrides Stigmatization.

Blum K, Gondré-Lewis MC, Modestino EJ, Lott L, Baron D, Siwicki D, McLaughlin T, Howeedy A, Krengel MH, Oscar-Berman M, Thanos PK, Elman I, Hauser M, Fried L, Bowirrat A, Badgaiyan RD.

Mol Neurobiol. 2019 May 23. doi: 10.1007/s12035-019-1600-8. [Epub ahead of print] Review.

PMID:
31124077
5.

Dopamine D4 receptor gene expression plays important role in extinction and reinstatement of cocaine-seeking behavior in mice.

Ananth M, Hetelekides EM, Hamilton J, Thanos PK.

Behav Brain Res. 2019 Jun 3;365:1-6. doi: 10.1016/j.bbr.2019.02.036. Epub 2019 Feb 21.

PMID:
30797855
6.

Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors.

Blum K, Gondré-Lewis MC, Baron D, Thanos PK, Braverman ER, Neary J, Elman I, Badgaiyan RD.

Front Psychiatry. 2018 Nov 27;9:548. doi: 10.3389/fpsyt.2018.00548. eCollection 2018. No abstract available.

7.

Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

Blum K, Modestino EJ, Badgaiyan RD, Baron D, Thanos PK, Elman I, Siwicki D, Febo M, Gold MS.

EC Psychol Psychiatr. 2018 Aug;7(8):564-579. Epub 2018 Jul 30.

8.

Chronic oral methylphenidate treatment increases microglial activation in rats.

Carias E, Hamilton J, Robison LS, Delis F, Eiden R, Quattrin T, Hadjiargyrou M, Komatsu D, Thanos PK.

J Neural Transm (Vienna). 2018 Dec;125(12):1867-1875. doi: 10.1007/s00702-018-1931-z. Epub 2018 Sep 20.

9.

Weekday-only chronic oral methylphenidate self-administration in male rats: Reversibility of the behavioral and physiological effects.

Carias E, Fricke D, Vijayashanthar A, Smith L, Somanesan R, Martin C, Kalinowski L, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK.

Behav Brain Res. 2019 Jan 1;356:189-196. doi: 10.1016/j.bbr.2018.08.014. Epub 2018 Aug 24.

PMID:
30149034
10.

Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference.

Robison LS, Alessi L, Thanos PK.

Behav Brain Res. 2018 Nov 1;353:176-184. doi: 10.1016/j.bbr.2018.07.009. Epub 2018 Jul 20.

PMID:
30036547
11.

Recovery from behavior and developmental effects of chronic oral methylphenidate following an abstinence period.

Martin C, Fricke D, Vijayashanthar A, Lowinger C, Koutsomitis D, Popoola D, Hadjiargyrou M, Komatsu DE, Thanos PK.

Pharmacol Biochem Behav. 2018 Sep;172:22-32. doi: 10.1016/j.pbb.2018.07.001. Epub 2018 Jul 18.

12.

Roux-en-Y gastric bypass surgery normalizes dopamine D1, D2, and DAT levels.

Hamilton J, Swenson S, Hajnal A, Thanos PK.

Synapse. 2018 Jul 10. doi: 10.1002/syn.22058. [Epub ahead of print]

PMID:
29992624
13.

Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity.

Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, Thanos PK, Bray GA, Neumaier JF, Zachariou V, Wang GJ, Volkow ND, Hurd YL.

Mol Psychiatry. 2018 Jun 28. doi: 10.1038/s41380-018-0120-7. [Epub ahead of print]

14.

Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic.

Blum K, Jacobs W, Modestino EJ, DiNubile N, Baron D, McLaughlin T, Siwicki D, Elman I, Moran M, Braverman ER, Thanos PK, Badgaiyan RD.

SEJ Surg Pain. 2018 Oct 4;1(1):1-11.

15.

Exercise Reduces Dopamine D1R and Increases D2R in Rats: Implications for Addiction.

Robison LS, Swenson S, Hamilton J, Thanos PK.

Med Sci Sports Exerc. 2018 Aug;50(8):1596-1602. doi: 10.1249/MSS.0000000000001627.

PMID:
29613999
16.

Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time.

Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK.

Behav Pharmacol. 2018 Sep;29(6):503-508. doi: 10.1097/FBP.0000000000000402.

17.

Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses.

Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3482-3487. doi: 10.1073/pnas.1721339115. Epub 2018 Mar 12. Erratum in: Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4313.

18.

Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels.

Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK.

Synapse. 2018 Jun;72(6):e22031. doi: 10.1002/syn.22031. Epub 2018 Feb 19.

19.

Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice.

Figueiredo A, Hamilton J, Marion M, Blum K, Kaczocha M, Haj-Dahmane S, Deutsch D, Thanos PK.

J Reward Defic Syndr Addict Sci. 2017;3(2):21-27. Epub 2017 Oct 31.

20.

Methylphenidate regulation of osteoclasts in a dose- and sex-dependent manner adversely affects skeletal mechanical integrity.

Uddin SMZ, Robison LS, Fricke D, Chernoff E, Hadjiargyrou M, Thanos PK, Komatsu DE.

Sci Rep. 2018 Jan 24;8(1):1515. doi: 10.1038/s41598-018-19894-x.

21.

Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid dependence.

Blum K, Chen ALC, Thanos PK, Febo M, Demetrovics Z, Dushaj K, Kovoor A, Baron D, Smith DE, Roy AK III, Fried L, Chen TJH, Chapman E Sr, Modestino EJ, Steinberg B, Badgaiyan RD.

Front Biosci (Elite Ed). 2018 Jan 1;10:175-196. Review.

PMID:
28930612
22.

The Food and Drug Addiction Epidemic: Targeting Dopamine Homeostasis.

Blum K, Thanos PK, Wang GJ, Febo M, Demetrovics Z, Modestino EJ, Braverman ER, Baron D, Badgaiyan RD, Gold MS.

Curr Pharm Des. 2018 Feb 12;23(39):6050-6061. doi: 10.2174/1381612823666170823101713. Review.

PMID:
28831923
23.

Oral haloperidol or olanzapine intake produces distinct and region-specific increase in cannabinoid receptor levels that is prevented by high fat diet.

Delis F, Rosko L, Shroff A, Leonard KE, Thanos PK.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):268-280. doi: 10.1016/j.pnpbp.2017.06.005. Epub 2017 Jun 13.

PMID:
28619471
24.

Enhanced functional connectivity and volume between cognitive and reward centers of naïve rodent brain produced by pro-dopaminergic agent KB220Z.

Febo M, Blum K, Badgaiyan RD, Perez PD, Colon-Perez LM, Thanos PK, Ferris CF, Kulkarni P, Giordano J, Baron D, Gold MS.

PLoS One. 2017 Apr 26;12(4):e0174774. doi: 10.1371/journal.pone.0174774. eCollection 2017.

25.

Substance use disorder a bio-directional subset of reward deficiency syndrome.

Blum K, Gold M, Demetrovics Z, Archer T, Thanos PK, Baron D, Badgaiyan RD.

Front Biosci (Landmark Ed). 2017 Jun 1;22:1534-1548.

PMID:
28410131
26.

Sex Differences in the Physiological and Behavioral Effects of Chronic Oral Methylphenidate Treatment in Rats.

Robison LS, Michaelos M, Gandhi J, Fricke D, Miao E, Lam CY, Mauceri A, Vitale M, Lee J, Paeng S, Komatsu DE, Hadjiargyrou M, Thanos PK.

Front Behav Neurosci. 2017 Mar 28;11:53. doi: 10.3389/fnbeh.2017.00053. eCollection 2017.

27.

Correction: Chronic Methamphetamine Effects on Brain Structure and Function in Rats.

Thanos PK, Kim R, Delis F, Ananth M, Chachati G, Rocco MJ, Masad I, Muniz JA, Grant SC, Gold MS, Cadet JL, Volkow ND.

PLoS One. 2017 Feb 8;12(2):e0172080. doi: 10.1371/journal.pone.0172080. eCollection 2017.

28.

Chronic oral methylphenidate treatment reversibly increases striatal dopamine transporter and dopamine type 1 receptor binding in rats.

Robison LS, Ananth M, Hadjiargyrou M, Komatsu DE, Thanos PK.

J Neural Transm (Vienna). 2017 May;124(5):655-667. doi: 10.1007/s00702-017-1680-4. Epub 2017 Jan 23.

29.

The Benefits of Genetic Addiction Risk Score (GARS) Testing in Substance Use Disorder (SUD).

Blum K, Modestino EJ, Gondre-Lewis M, Chapman EJ, Neary J, Siwicki D, Baron D, Hauser M, Smith DE, Roy AK, Thanos PK, Steinberg B, McLaughlin T, Fried L, Barh D, Dunston GA, Badgaiyan RD.

Int J Genom Data Min. 2018;2018(1). pii: 115. doi: 10.29014/IJGD-115.000015. Epub 2018 Jan 15.

30.

Hypothesizing Las Vegas and Sutherland Springs Mass Shooters Suffer from Reward Deficiency Syndrome: "Born Bad".

McLaughlin T, Blum K, Steinberg B, Siwicki D, Campione J, Badgaiyan RD, Braverman ER, Modestino EJ, Gondré-Lewis MC, Baron D, Mash DC, Giordano J, Thanos PK.

J Reward Defic Syndr Addict Sci. 2017;3(2):28-31. doi: 10.17756/jrdsas.2017-038. Epub 2017 Dec 30.

31.

Effects of chronic methamphetamine on psychomotor and cognitive functions and dopamine signaling in the brain.

Thanos PK, Kim R, Delis F, Rocco MJ, Cho J, Volkow ND.

Behav Brain Res. 2017 Mar 1;320:282-290. doi: 10.1016/j.bbr.2016.12.010. Epub 2016 Dec 16.

PMID:
27993694
32.

Dopamine homeostasis: brain functional connectivity in reward deficiency syndrome.

Febo M, Blum K, Badgaiyan RD, Baron D, Thanos PK, Colon-Perez LM, Demortrovics Z, Gold MS.

Front Biosci (Landmark Ed). 2017 Jan 1;22:669-691. Review.

PMID:
27814639
33.

Suboptimal maternal diets alter mu opioid receptor and dopamine type 1 receptor binding but exert no effect on dopamine transporters in the offspring brain.

Thanos PK, Zhuo J, Robison L, Kim R, Ananth M, Choai I, Grunseich A, Grissom NM, George R, Delis F, Reyes TM.

Int J Dev Neurosci. 2018 Feb;64:21-28. doi: 10.1016/j.ijdevneu.2016.09.008. Epub 2016 Sep 22.

34.

Chronic Methamphetamine Effects on Brain Structure and Function in Rats.

Thanos PK, Kim R, Delis F, Ananth M, Chachati G, Rocco MJ, Masad I, Muniz JA, Grant SC, Gold MS, Cadet JL, Volkow ND.

PLoS One. 2016 Jun 8;11(6):e0155457. doi: 10.1371/journal.pone.0155457. eCollection 2016. Erratum in: PLoS One. 2017 Feb 8;12 (2):e0172080.

35.

Ethanol Induced Brain Lipid Changes in Mice Assessed by Mass Spectrometry.

Roux A, Jackson SN, Muller L, Barbacci D, O'Rourke J, Thanos PK, Volkow ND, Balaban C, Schultz JA, Woods AS.

ACS Chem Neurosci. 2016 Aug 17;7(8):1148-56. doi: 10.1021/acschemneuro.6b00120. Epub 2016 Jun 20.

PMID:
27269520
36.

Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26.

Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D, Kaczocha M.

Front Psychiatry. 2016 Apr 5;7:54. doi: 10.3389/fpsyt.2016.00054. eCollection 2016.

37.

Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior.

Thanos PK, Hamilton J, O'Rourke JR, Napoli A, Febo M, Volkow ND, Blum K, Gold M.

Oncotarget. 2016 Apr 12;7(15):19111-23. doi: 10.18632/oncotarget.8088.

38.

Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice.

Thanos PK, Malave L, Delis F, Mangine P, Kane K, Grunseich A, Vitale M, Greengard P, Volkow ND.

Synapse. 2016 Jul;70(7):293-301. doi: 10.1002/syn.21904. Epub 2016 May 4.

PMID:
26990537
39.

Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term.

Blum K, Badgaiyan RD, Braverman ER, Dushaj K, Li M, Thanos PK, Demetrovics Z, Febo M.

J Reward Defic Syndr Addict Sci. 2016;2(1):14-21. doi: 10.17756/jrdsas.2016-023. Epub 2016 Jun 29.

40.

Mouse Social Interaction Test (MoST): a quantitative computer automated analysis of behavior.

Thanos PK, Restif C, O'Rourke JR, Lam CY, Metaxas D.

J Neural Transm (Vienna). 2017 Jan;124(1):3-11. doi: 10.1007/s00702-015-1487-0. Epub 2015 Dec 24.

PMID:
26704381
41.

Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms.

Kaczocha M, Glaser ST, Maher T, Clavin B, Hamilton J, O'Rourke J, Rebecchi M, Puopolo M, Owada Y, Thanos PK.

Mol Pain. 2015 Aug 28;11:52. doi: 10.1186/s12990-015-0056-8.

42.

Roux-en-Y Gastric Bypass Alters Brain Activity in Regions that Underlie Reward and Taste Perception.

Thanos PK, Michaelides M, Subrize M, Miller ML, Bellezza R, Cooney RN, Leggio L, Wang GJ, Rogers AM, Volkow ND, Hajnal A.

PLoS One. 2015 Jun 3;10(6):e0125570. doi: 10.1371/journal.pone.0125570. eCollection 2015.

43.

Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters.

Delis F, Rombola C, Bellezza R, Rosko L, Grandy DK, Volkow ND, Thanos PK.

Front Behav Neurosci. 2015 May 12;9:118. doi: 10.3389/fnbeh.2015.00118. eCollection 2015.

44.

Neurogenetics and gene therapy for reward deficiency syndrome: are we going to the Promised Land?

Blum K, Thanos PK, Badgaiyan RD, Febo M, Oscar-Berman M, Fratantonio J, Demotrovics Z, Gold MS.

Expert Opin Biol Ther. 2015 Jul;15(7):973-85. doi: 10.1517/14712598.2015.1045871. Epub 2015 May 14. Review.

PMID:
25974314
45.

The effect of dopamine D4 receptor density on novelty seeking, activity, social interaction, and alcohol binge drinking in adult mice.

Thanos PK, Roushdy K, Sarwar Z, Rice O, Ashby CR Jr, Grandy DK.

Synapse. 2015 Jul;69(7):356-64. doi: 10.1002/syn.21822. Epub 2015 May 20.

PMID:
25914336
46.

Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain.

Volkow ND, Wang GJ, Logan J, Alexoff D, Fowler JS, Thanos PK, Wong C, Casado V, Ferre S, Tomasi D.

Transl Psychiatry. 2015 Apr 14;5:e549. doi: 10.1038/tp.2015.46.

47.

Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner?

Blum K, Febo M, Thanos PK, Baron D, Fratantonio J, Gold M.

Mol Neurobiol. 2015 Dec;52(3):1862-1869. doi: 10.1007/s12035-015-9110-9. Epub 2015 Mar 10. Review.

48.

A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior.

Thanos PK, Robison LS, Steier J, Hwang YF, Cooper T, Swanson JM, Komatsu DE, Hadjiargyrou M, Volkow ND.

Pharmacol Biochem Behav. 2015 Apr;131:143-53. doi: 10.1016/j.pbb.2015.01.005. Epub 2015 Jan 29.

49.

Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction.

Blum K, Thanos PK, Oscar-Berman M, Febo M, Baron D, Badgaiyan RD, Gardner E, Demetrovics Z, Fahlke C, Haberstick BC, Dushaj K, Gold MS.

J Reward Defic Syndr. 2015;1(3):95-104. Epub 2015 Oct 23.

50.

Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents.

Roux A, Muller L, Jackson SN, Baldwin K, Womack V, Pagiazitis JG, O'Rourke JR, Thanos PK, Balaban C, Schultz JA, Volkow ND, Woods AS.

ACS Chem Neurosci. 2015 Feb 18;6(2):247-59. doi: 10.1021/cn500174c. Epub 2014 Dec 1.

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