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Items: 1 to 50 of 90

1.

The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.

Nikopoulou C, Panagopoulos G, Sianidis G, Psarra E, Ford E, Thanos D.

Mol Cell. 2018 Jun 27. pii: S1097-2765(18)30464-7. doi: 10.1016/j.molcel.2018.06.019. [Epub ahead of print]

PMID:
30017585
2.

Perturbation of transcriptome in non-neoplastic salivary gland epithelial cell lines derived from patients with primary Sjögren's syndrome.

Vakrakou AG, Polyzos A, Kapsogeorgou EK, Thanos D, Manoussakis MN.

Data Brief. 2017 Dec 12;17:194-199. doi: 10.1016/j.dib.2017.12.023. eCollection 2018 Apr.

3.

Hippocampal lipidome and transcriptome profile alterations triggered by acute exposure of mice to GSM 1800 MHz mobile phone radiation: An exploratory study.

Fragopoulou AF, Polyzos A, Papadopoulou MD, Sansone A, Manta AK, Balafas E, Kostomitsopoulos N, Skouroliakou A, Chatgilialoglu C, Georgakilas A, Stravopodis DJ, Ferreri C, Thanos D, Margaritis LH.

Brain Behav. 2018 Jun;8(6):e01001. doi: 10.1002/brb3.1001. Epub 2018 May 22.

4.

The Histone Variant MacroH2A Blocks Cellular Reprogramming by Inhibiting Mesenchymal-to-Epithelial Transition.

Pliatska M, Kapasa M, Kokkalis A, Polyzos A, Thanos D.

Mol Cell Biol. 2018 Apr 30;38(10). pii: e00669-17. doi: 10.1128/MCB.00669-17. Print 2018 May 15.

PMID:
29483300
5.

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

Matak A, Lahiri P, Ford E, Pabst D, Kashofer K, Stellas D, Thanos D, Zatloukal K.

Hepatology. 2017 Nov 23. doi: 10.1002/hep.29679. [Epub ahead of print]

PMID:
29171037
6.

Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation.

Vakrakou AG, Polyzos A, Kapsogeorgou EK, Thanos D, Manoussakis MN.

J Autoimmun. 2018 Jan;86:62-74. doi: 10.1016/j.jaut.2017.09.007. Epub 2017 Oct 14.

PMID:
29033144
7.

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness.

Galani IE, Triantafyllia V, Eleminiadou EE, Koltsida O, Stavropoulos A, Manioudaki M, Thanos D, Doyle SE, Kotenko SV, Thanopoulou K, Andreakos E.

Immunity. 2017 May 16;46(5):875-890.e6. doi: 10.1016/j.immuni.2017.04.025.

8.

Erratum to 'Exploring and exploiting the systemic effects of deregulated replication licensing' [Seminars in Cancer Biology 37-38C, (2016) 3-15].

Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.

Semin Cancer Biol. 2017 Apr;43:180. doi: 10.1016/j.semcancer.2017.02.002. Epub 2017 Feb 21. No abstract available.

PMID:
28254408
9.

Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster.

Manta AK, Papadopoulou D, Polyzos AP, Fragopoulou AF, Skouroliakou AS, Thanos D, Stravopodis DJ, Margaritis LH.

Fly (Austin). 2017 Apr 3;11(2):75-95. doi: 10.1080/19336934.2016.1270487. Epub 2016 Dec 14.

10.

Transcription Factor Ets-2 Acts as a Preinduction Repressor of Interleukin-2 (IL-2) Transcription in Naive T Helper Lymphocytes.

Panagoulias I, Georgakopoulos T, Aggeletopoulou I, Agelopoulos M, Thanos D, Mouzaki A.

J Biol Chem. 2016 Dec 23;291(52):26707-26721. doi: 10.1074/jbc.M116.762179. Epub 2016 Nov 3.

11.

The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions.

Nanou A, Toumpeki C, Lavigne MD, Lazou V, Demmers J, Paparountas T, Thanos D, Katsantoni E.

Nucleic Acids Res. 2017 Jan 9;45(1):142-154. doi: 10.1093/nar/gkw832. Epub 2016 Sep 19.

12.

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.

Galanos P, Vougas K, Walter D, Polyzos A, Maya-Mendoza A, Haagensen EJ, Kokkalis A, Roumelioti FM, Gagos S, Tzetis M, Canovas B, Igea A, Ahuja AK, Zellweger R, Havaki S, Kanavakis E, Kletsas D, Roninson IB, Garbis SD, Lopes M, Nebreda A, Thanos D, Blow JJ, Townsend P, Sørensen CS, Bartek J, Gorgoulis VG.

Nat Cell Biol. 2016 Jul;18(7):777-89. doi: 10.1038/ncb3378. Epub 2016 Jun 20.

PMID:
27323328
13.

Exploring and exploiting the systemic effects of deregulated replication licensing.

Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.

Semin Cancer Biol. 2016 Jun;37-38:3-15. doi: 10.1016/j.semcancer.2015.12.002. Epub 2015 Dec 17. Review. Erratum in: Semin Cancer Biol. 2017 Apr;43:180.

PMID:
26707000
14.

Incidental thyroid C cell hyperplasia: clinical significance and implications in practice.

Sakorafas GH, Nasikas D, Thanos D, Gantzoulas S.

Oncol Res Treat. 2015;38(5):249-52. doi: 10.1159/000381605. Epub 2015 Apr 17. Review.

PMID:
25966772
15.

Composite macroH2A/NRF-1 Nucleosomes Suppress Noise and Generate Robustness in Gene Expression.

Lavigne MD, Vatsellas G, Polyzos A, Mantouvalou E, Sianidis G, Maraziotis I, Agelopoulos M, Thanos D.

Cell Rep. 2015 May 19;11(7):1090-101. doi: 10.1016/j.celrep.2015.04.022. Epub 2015 May 7.

16.

A method for generating highly multiplexed ChIP-seq libraries.

Ford E, Nikopoulou C, Kokkalis A, Thanos D.

BMC Res Notes. 2014 May 22;7:312. doi: 10.1186/1756-0500-7-312.

17.

Stochastic responses are not left to pure "chance".

Banos A, Agelopoulos M, Thanos D.

Cell. 2013 Oct 24;155(3):499-502. doi: 10.1016/j.cell.2013.10.002. Epub 2013 Oct 24.

18.

Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements.

Antonaki A, Demetriades C, Polyzos A, Banos A, Vatsellas G, Lavigne MD, Apostolou E, Mantouvalou E, Papadopoulou D, Mosialos G, Thanos D.

J Biol Chem. 2011 Nov 4;286(44):38768-82. doi: 10.1074/jbc.M111.234161. Epub 2011 Sep 5.

19.

Gene regulatory networks modelling using a dynamic evolutionary hybrid.

Maraziotis IA, Dragomir A, Thanos D.

BMC Bioinformatics. 2010 Mar 18;11:140. doi: 10.1186/1471-2105-11-140.

20.

The transcriptional code of human IFN-beta gene expression.

Ford E, Thanos D.

Biochim Biophys Acta. 2010 Mar-Apr;1799(3-4):328-36. doi: 10.1016/j.bbagrm.2010.01.010. Epub 2010 Jan 30. Review.

PMID:
20116463
21.

Transcription factors mediate long-range enhancer-promoter interactions.

Nolis IK, McKay DJ, Mantouvalou E, Lomvardas S, Merika M, Thanos D.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20222-7. doi: 10.1073/pnas.0902454106. Epub 2009 Nov 18.

22.

Time's up: bursting out of transcription.

Ford E, Thanos D.

Cell. 2009 Aug 7;138(3):430-2. doi: 10.1016/j.cell.2009.07.023.

23.

A dimer-specific function of the transcription factor NFATp.

Falvo JV, Lin CH, Tsytsykova AV, Hwang PK, Thanos D, Goldfeld AE, Maniatis T.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19637-42. doi: 10.1073/pnas.0810648105. Epub 2008 Dec 5.

24.

Virus Infection Induces NF-kappaB-dependent interchromosomal associations mediating monoallelic IFN-beta gene expression.

Apostolou E, Thanos D.

Cell. 2008 Jul 11;134(1):85-96. doi: 10.1016/j.cell.2008.05.052.

25.

Biochemistry and molecular biology research achievements in Greece.

Thireos G, Panayotou G, Thanos D.

IUBMB Life. 2008 May;60(5):254-7. doi: 10.1002/iub.64. No abstract available.

26.

S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway.

Prinarakis E, Chantzoura E, Thanos D, Spyrou G.

EMBO J. 2008 Mar 19;27(6):865-75. doi: 10.1038/emboj.2008.28. Epub 2008 Feb 28.

27.

Linking differential chromatin loops to transcriptional decisions.

Apostolou E, Thanos D.

Mol Cell. 2008 Feb 1;29(2):154-6. doi: 10.1016/j.molcel.2008.01.008.

28.

Bypassing the requirements for epigenetic modifications in gene transcription by increasing enhancer strength.

Koutroubas G, Merika M, Thanos D.

Mol Cell Biol. 2008 Feb;28(3):926-38. Epub 2007 Nov 19.

29.

Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression.

Tsytsykova AV, Falvo JV, Schmidt-Supprian M, Courtois G, Thanos D, Goldfeld AE.

J Biol Chem. 2007 Apr 20;282(16):11629-38. Epub 2007 Feb 15.

30.
31.

CIITA regulates transcription onset viaSer5-phosphorylation of RNA Pol II.

Spilianakis C, Kretsovali A, Agalioti T, Makatounakis T, Thanos D, Papamatheakis J.

EMBO J. 2003 Oct 1;22(19):5125-36.

32.

Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure.

Guan Z, Giustetto M, Lomvardas S, Kim JH, Miniaci MC, Schwartz JH, Thanos D, Kandel ER.

Cell. 2002 Nov 15;111(4):483-93.

33.

Deciphering the transcriptional histone acetylation code for a human gene.

Agalioti T, Chen G, Thanos D.

Cell. 2002 Nov 1;111(3):381-92.

34.

Modifying gene expression programs by altering core promoter chromatin architecture.

Lomvardas S, Thanos D.

Cell. 2002 Jul 26;110(2):261-71.

PMID:
12150933
35.

Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter.

Escalante CR, Shen L, Thanos D, Aggarwal AK.

Structure. 2002 Mar;10(3):383-91.

36.

The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription.

Chen-Park FE, Huang DB, Noro B, Thanos D, Ghosh G.

J Biol Chem. 2002 Jul 5;277(27):24701-8. Epub 2002 Apr 22.

37.

Opening chromatin.

Lomvardas S, Thanos D.

Mol Cell. 2002 Feb;9(2):209-11. Review.

38.

Nucleosome sliding via TBP DNA binding in vivo.

Lomvardas S, Thanos D.

Cell. 2001 Sep 21;106(6):685-96.

39.

Coordination of a transcriptional switch by HMGI(Y) acetylation.

Munshi N, Agalioti T, Lomvardas S, Merika M, Chen G, Thanos D.

Science. 2001 Aug 10;293(5532):1133-6.

40.

Overexpression of proteins HMGA1 induces cell cycle deregulation and apoptosis in normal rat thyroid cells.

Fedele M, Pierantoni GM, Berlingieri MT, Battista S, Baldassarre G, Munshi N, Dentice M, Thanos D, Santoro M, Viglietto G, Fusco A.

Cancer Res. 2001 Jun 1;61(11):4583-90.

41.

Enhanceosomes.

Merika M, Thanos D.

Curr Opin Genet Dev. 2001 Apr;11(2):205-8. Review.

PMID:
11250145
42.

The IFN-beta enhancer: a paradigm for understanding activation and repression of inducible gene expression.

Munshi N, Yie Y, Merika M, Senger K, Lomvardas S, Agalioti T, Thanos D.

Cold Spring Harb Symp Quant Biol. 1999;64:149-59. Review. No abstract available.

PMID:
11232280
43.

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter.

Agalioti T, Lomvardas S, Parekh B, Yie J, Maniatis T, Thanos D.

Cell. 2000 Nov 10;103(4):667-78.

44.

Gene repression by coactivator repulsion.

Senger K, Merika M, Agalioti T, Yie J, Escalante CR, Chen G, Aggarwal AK, Thanos D.

Mol Cell. 2000 Oct;6(4):931-7.

45.

The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression.

Chau KY, Munshi N, Keane-Myers A, Cheung-Chau KW, Tai AK, Manfioletti G, Dorey CK, Thanos D, Zack DJ, Ono SJ.

J Neurosci. 2000 Oct 1;20(19):7317-24.

46.

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.

O'Neill DW, Schoetz SS, Lopez RA, Castle M, Rabinowitz L, Shor E, Krawchuk D, Goll MG, Renz M, Seelig HP, Han S, Seong RH, Park SD, Agalioti T, Munshi N, Thanos D, Erdjument-Bromage H, Tempst P, Bank A.

Mol Cell Biol. 2000 Oct;20(20):7572-82.

47.

Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter.

Falvo JV, Uglialoro AM, Brinkman BM, Merika M, Parekh BS, Tsai EY, King HC, Morielli AD, Peralta EG, Maniatis T, Thanos D, Goldfeld AE.

Mol Cell Biol. 2000 Mar;20(6):2239-47.

48.

Mechanism by which the IFN-beta enhanceosome activates transcription.

Yie J, Senger K, Thanos D.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13108-13.

49.

Transcriptional activation by NF-kappaB requires multiple coactivators.

Sheppard KA, Rose DW, Haque ZK, Kurokawa R, McInerney E, Westin S, Thanos D, Rosenfeld MG, Glass CK, Collins T.

Mol Cell Biol. 1999 Sep;19(9):6367-78.

50.

The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome.

Yie J, Merika M, Munshi N, Chen G, Thanos D.

EMBO J. 1999 Jun 1;18(11):3074-89.

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