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Items: 1 to 50 of 208

1.

Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts.

Parker MM, Hao Y, Guo F, Pham B, Chase R, Platig J, Cho MH, Hersh CP, Thannickal VJ, Crapo J, Washko G, Randell SH, Silverman EK, San José Estépar R, Zhou X, Castaldi PJ.

Elife. 2019 Jul 25;8. pii: e42720. doi: 10.7554/eLife.42720.

2.

Remember Me? The Bone Marrow in Pulmonary Fibrosis.

Rangarajan S, Thannickal VJ.

Am J Respir Crit Care Med. 2019 Jun 17. doi: 10.1164/rccm.201906-1101ED. [Epub ahead of print] No abstract available.

PMID:
31206314
3.

NADPH Oxidases and Aging Models of Lung Fibrosis.

Bernard K, Thannickal VJ.

Methods Mol Biol. 2019;1982:487-496. doi: 10.1007/978-1-4939-9424-3_29.

PMID:
31172491
4.

Modeling Fibrosis in 3D Organoids Reveals New Epithelial Restraints on Fibroblasts.

Chanda D, Thannickal VJ.

Am J Respir Cell Mol Biol. 2019 May 15. doi: 10.1165/rcmb.2019-0153ED. [Epub ahead of print] No abstract available.

PMID:
31091962
5.

FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury.

Yuan T, Volckaert T, Redente EF, Hopkins S, Klinkhammer K, Wasnick R, Chao CM, Yuan J, Zhang JS, Yao C, Majka S, Stripp BR, Günther A, Riches DWH, Bellusci S, Thannickal VJ, De Langhe SP.

Stem Cell Reports. 2019 May 14;12(5):1041-1055. doi: 10.1016/j.stemcr.2019.04.003. Epub 2019 May 2.

6.

Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis.

Barnes JW, Duncan D, Helton S, Hutcheson S, Kurundkar D, Logsdon NJ, Locy M, Garth J, Denson R, Farver C, Vo HT, King G, Kentrup D, Faul C, Kulkarni T, De Andrade JA, Yu Z, Matalon S, Thannickal VJ, Krick S.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L141-L154. doi: 10.1152/ajplung.00246.2018. Epub 2019 May 1.

PMID:
31042083
7.

Update in Pulmonary Fibrosis 2018.

Sgalla G, Kulkarni T, Antin-Ozerkis D, Thannickal VJ, Richeldi L.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):292-300. doi: 10.1164/rccm.201903-0542UP. No abstract available.

PMID:
31022351
8.

The Aging Lung and Idiopathic Pulmonary Fibrosis.

Gulati S, Thannickal VJ.

Am J Med Sci. 2019 May;357(5):384-389. doi: 10.1016/j.amjms.2019.02.008. Epub 2019 Feb 12. Review.

PMID:
31010465
9.

Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury.

Surolia R, Li FJ, Wang Z, Li H, Dsouza K, Thomas V, Mirov S, Pérez-Sala D, Athar M, Thannickal VJ, Antony VB.

JCI Insight. 2019 Apr 4;4(7). pii: 123253. doi: 10.1172/jci.insight.123253. eCollection 2019 Apr 4.

10.

Pulmonary fibrosis: "idiopathic" is not "cryptogenic".

Wells AU, Brown KK, Flaherty KR, Kolb M, Thannickal VJ; IPF Consensus Working Group; IPF Consensus Working Group:.

Eur Respir J. 2019 Mar 18;53(3). pii: 1900400. doi: 10.1183/13993003.00400-2019. Print 2019 Mar. No abstract available.

PMID:
30886028
11.

Idiopathic interstitial pneumonia or idiopathic interstitial pneumonitis: what's in a name?

Wells AU, Brown KK, Flaherty KR, Kolb M, Thannickal VJ; IPF Consensus Working Group; IPF Consensus Working Group:.

Eur Respir J. 2019 Feb 14;53(2). pii: 1801939. doi: 10.1183/13993003.01939-2018. Print 2019 Feb. No abstract available.

PMID:
30765483
12.

Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury.

Cui H, Banerjee S, Guo S, Xie N, Ge J, Jiang D, Zörnig M, Thannickal VJ, Liu G.

JCI Insight. 2019 Feb 21;4(4). pii: 124522. doi: 10.1172/jci.insight.124522. eCollection 2019 Feb 21.

13.

Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling.

Volckaert T, Yuan T, Yuan J, Boateng E, Hopkins S, Zhang JS, Thannickal VJ, Fässler R, De Langhe SP.

Development. 2019 Jan 16;146(2). pii: dev166454. doi: 10.1242/dev.166454.

14.

SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury.

Kurundkar D, Kurundkar AR, Bone NB, Becker EJ Jr, Liu W, Chacko B, Darley-Usmar V, Zmijewski JW, Thannickal VJ.

JCI Insight. 2019 Jan 10;4(1). pii: 120722. doi: 10.1172/jci.insight.120722. [Epub ahead of print]

15.

Mechanisms for the Resolution of Organ Fibrosis.

Horowitz JC, Thannickal VJ.

Physiology (Bethesda). 2019 Jan 1;34(1):43-55. doi: 10.1152/physiol.00033.2018. Review.

PMID:
30540232
16.

Fibronectin on the Surface of Extracellular Vesicles Mediates Fibroblast Invasion.

Chanda D, Otoupalova E, Hough KP, Locy ML, Bernard K, Deshane JS, Sanderson RD, Mobley JA, Thannickal VJ.

Am J Respir Cell Mol Biol. 2019 Mar;60(3):279-288. doi: 10.1165/rcmb.2018-0062OC.

PMID:
30321056
17.

Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury.

Yuan T, Volckaert T, Chanda D, Thannickal VJ, De Langhe SP.

Front Genet. 2018 Sep 25;9:418. doi: 10.3389/fgene.2018.00418. eCollection 2018. Review.

18.

Ambulatory oxygen and quality of life in interstitial lung disease.

Page DB, Thannickal VJ.

Lancet Respir Med. 2018 Oct;6(10):730-731. doi: 10.1016/S2213-2600(18)30337-0. Epub 2018 Aug 28. No abstract available.

PMID:
30170903
19.

BETting on Novel Treatments for Asthma: Bromodomain 4 Inhibitors.

Sanders YY, Thannickal VJ.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):7-8. doi: 10.1165/rcmb.2018-0271ED. No abstract available.

PMID:
30157386
20.

Developmental pathways in the pathogenesis of lung fibrosis.

Chanda D, Otoupalova E, Smith SR, Volckaert T, De Langhe SP, Thannickal VJ.

Mol Aspects Med. 2019 Feb;65:56-69. doi: 10.1016/j.mam.2018.08.004. Epub 2018 Aug 23. Review.

PMID:
30130563
21.

Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts.

Bai L, Bernard K, Tang X, Hu M, Horowitz JC, Thannickal VJ, Sanders YY.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):49-57. doi: 10.1165/rcmb.2018-0180OC.

PMID:
30130138
22.

Author Correction: Metformin reverses established lung fibrosis in a bleomycin model.

Rangarajan S, Bone NB, Zmijewska AA, Jiang S, Park DW, Bernard K, Locy ML, Ravi S, Deshane J, Mannon RB, Abraham E, Darley-Usmar V, Thannickal VJ, Zmijewski JW.

Nat Med. 2018 Oct;24(10):1627. doi: 10.1038/s41591-018-0170-z.

PMID:
30104770
23.

Cellular Senescence in Chronic Obstructive Pulmonary Disease: Multifaceted and Multifunctional.

Antony VB, Thannickal VJ.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):135-136. doi: 10.1165/rcmb.2018-0061ED. No abstract available.

PMID:
30067090
24.

Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells.

Hough KP, Trevor JL, Strenkowski JG, Wang Y, Chacko BK, Tousif S, Chanda D, Steele C, Antony VB, Dokland T, Ouyang X, Zhang J, Duncan SR, Thannickal VJ, Darley-Usmar VM, Deshane JS.

Redox Biol. 2018 Sep;18:54-64. doi: 10.1016/j.redox.2018.06.009. Epub 2018 Jun 25.

25.

Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics.

Hough KP, Wilson LS, Trevor JL, Strenkowski JG, Maina N, Kim YI, Spell ML, Wang Y, Chanda D, Dager JR, Sharma NS, Curtiss M, Antony VB, Dransfield MT, Chaplin DD, Steele C, Barnes S, Duncan SR, Prasain JK, Thannickal VJ, Deshane JS.

Sci Rep. 2018 Jul 9;8(1):10340. doi: 10.1038/s41598-018-28655-9.

26.

Metformin reverses established lung fibrosis in a bleomycin model.

Rangarajan S, Bone NB, Zmijewska AA, Jiang S, Park DW, Bernard K, Locy ML, Ravi S, Deshane J, Mannon RB, Abraham E, Darley-Usmar V, Thannickal VJ, Zmijewski JW.

Nat Med. 2018 Aug;24(8):1121-1127. doi: 10.1038/s41591-018-0087-6. Epub 2018 Jul 2. Erratum in: Nat Med. 2018 Oct;24(10):1627.

27.

Reversing Mechanoinductive DSP Expression by CRISPR/dCas9-mediated Epigenome Editing.

Qu J, Zhu L, Zhou Z, Chen P, Liu S, Locy ML, Thannickal VJ, Zhou Y.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):599-609. doi: 10.1164/rccm.201711-2242OC.

PMID:
29924937
28.

Peroxidasin contributes to lung host defense by direct binding and killing of gram-negative bacteria.

Shi R, Cao Z, Li H, Graw J, Zhang G, Thannickal VJ, Cheng G.

PLoS Pathog. 2018 May 18;14(5):e1007026. doi: 10.1371/journal.ppat.1007026. eCollection 2018 May.

29.

What's in a name? That which we call IPF, by any other name would act the same.

Wells AU, Brown KK, Flaherty KR, Kolb M, Thannickal VJ; IPF Consensus Working Group.

Eur Respir J. 2018 May 17;51(5). pii: 1800692. doi: 10.1183/13993003.00692-2018. Print 2018 May. Review.

PMID:
29773608
30.

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli.

Dodi AE, Ajayi IO, Chang C, Beard M, Ashley SL, Huang SK, Thannickal VJ, Tschumperlin DJ, Sisson TH, Horowitz JC.

Respir Res. 2018 May 10;19(1):91. doi: 10.1186/s12931-018-0801-4.

31.

Is personalized medicine a realistic goal in idiopathic pulmonary fibrosis?

Thannickal VJ, Antony VB.

Expert Rev Respir Med. 2018 Jun;12(6):441-443. doi: 10.1080/17476348.2018.1464913. Epub 2018 Apr 19. No abstract available.

32.

Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Nov;73:77-104. doi: 10.1016/j.matbio.2018.03.005. Epub 2018 Mar 8. Review.

PMID:
29524630
33.

Idiopathic pulmonary fibrosis: idiopathic no more?

Thannickal VJ, Wells A, Kolb M.

Lancet Respir Med. 2018 Feb;6(2):84-85. doi: 10.1016/S2213-2600(18)30022-5. No abstract available.

PMID:
29413084
34.

Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.

Bernard K, Logsdon NJ, Benavides GA, Sanders Y, Zhang J, Darley-Usmar VM, Thannickal VJ.

J Biol Chem. 2018 Jan 26;293(4):1218-1228. doi: 10.1074/jbc.RA117.000444. Epub 2017 Dec 8.

35.

The Lung Likes the Little Fella miR-29.

Liu G, Thannickal VJ.

Am J Respir Cell Mol Biol. 2017 Dec;57(6):637-638. doi: 10.1165/rcmb.2017-0266ED. No abstract available.

PMID:
29192829
36.

Mitochondrial Dysfunction in Pulmonary Fibrosis.

Rangarajan S, Bernard K, Thannickal VJ.

Ann Am Thorac Soc. 2017 Nov;14(Supplement_5):S383-S388. doi: 10.1513/AnnalsATS.201705-370AW. Review.

37.

Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells.

Volckaert T, Yuan T, Chao CM, Bell H, Sitaula A, Szimmtenings L, El Agha E, Chanda D, Majka S, Bellusci S, Thannickal VJ, Fässler R, De Langhe SP.

Dev Cell. 2017 Oct 9;43(1):48-59.e5. doi: 10.1016/j.devcel.2017.09.003.

38.

Measures of Frailty in Chronic Lung Diseases.

Luckhardt T, Thannickal VJ.

Ann Am Thorac Soc. 2017 Aug;14(8):1266-1267. doi: 10.1513/AnnalsATS.201706-420ED. No abstract available.

39.

Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients.

Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E, Zhang K, Kumar R, Rangarajan S, Eipers P, Wang Y, Srivastava RK, Rodriguez Dager JV, Athar M, Morrow C, Hoopes CW, Chaplin DD, Thannickal VJ, Deshane JS.

J Heart Lung Transplant. 2017 Jul 15. pii: S1053-2498(17)31898-3. doi: 10.1016/j.healun.2017.07.007. [Epub ahead of print]

40.

Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis.

Li FJ, Surolia R, Li H, Wang Z, Kulkarni T, Liu G, de Andrade JA, Kass DJ, Thannickal VJ, Duncan SR, Antony VB.

J Immunol. 2017 Sep 1;199(5):1596-1605. doi: 10.4049/jimmunol.1700473. Epub 2017 Jul 28.

41.

Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease.

Jiang C, Liu G, Luckhardt T, Antony V, Zhou Y, Carter AB, Thannickal VJ, Liu RM.

Aging Cell. 2017 Oct;16(5):1114-1124. doi: 10.1111/acel.12643. Epub 2017 Jul 19.

42.

DNA methylation regulated gene expression in organ fibrosis.

Zhang X, Hu M, Lyu X, Li C, Thannickal VJ, Sanders YY.

Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2389-2397. doi: 10.1016/j.bbadis.2017.05.010. Epub 2017 May 10. Review.

43.

The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop.

Budinger GRS, Kohanski RA, Gan W, Kobor MS, Amaral LA, Armanios M, Kelsey KT, Pardo A, Tuder R, Macian F, Chandel N, Vaughan D, Rojas M, Mora AL, Kovacs E, Duncan SR, Finkel T, Choi A, Eickelberg O, Chen D, Agusti A, Selman M, Balch WE, Busse P, Lin A, Morimoto R, Sznajder JI, Thannickal VJ.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1492-1500. doi: 10.1093/gerona/glx090. Review.

44.

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

Jenkins RG, Moore BB, Chambers RC, Eickelberg O, Königshoff M, Kolb M, Laurent GJ, Nanthakumar CB, Olman MA, Pardo A, Selman M, Sheppard D, Sime PJ, Tager AM, Tatler AL, Thannickal VJ, White ES; ATS Assembly on Respiratory Cell and Molecular Biology.

Am J Respir Cell Mol Biol. 2017 May;56(5):667-679. doi: 10.1165/rcmb.2017-0096ST.

45.

Low-dose cadmium exposure induces peribronchiolar fibrosis through site-specific phosphorylation of vimentin.

Li FJ, Surolia R, Li H, Wang Z, Liu G, Liu RM, Mirov SB, Athar M, Thannickal VJ, Antony VB.

Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L80-L91. doi: 10.1152/ajplung.00087.2017. Epub 2017 Apr 27.

46.

3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.

Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB.

JCI Insight. 2017 Apr 20;2(8). pii: 94088. doi: 10.1172/jci.insight.94088. eCollection 2017 Apr 20. No abstract available.

47.

Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.

Ghatak S, Markwald RR, Hascall VC, Dowling W, Lottes RG, Baatz JE, Beeson G, Beeson CC, Perrella MA, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10465-10489. doi: 10.1074/jbc.M116.752451. Epub 2017 Apr 7.

48.

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis.

Ghatak S, Hascall VC, Markwald RR, Feghali-Bostwick C, Artlett CM, Gooz M, Bogatkevich GS, Atanelishvili I, Silver RM, Wood J, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10490-10519. doi: 10.1074/jbc.M116.752469. Epub 2017 Apr 7.

49.

Focal adhesion kinase signaling determines the fate of lung epithelial cells in response to TGF-β.

Ding Q, Subramanian I, Luckhardt TR, Che P, Waghray M, Zhao XK, Bone N, Kurundkar AR, Hecker L, Hu M, Zhou Y, Horowitz JC, Vittal R, Thannickal VJ.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L926-L935. doi: 10.1152/ajplung.00121.2016. Epub 2017 Mar 30.

50.

3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.

Surolia R, Li FJ, Wang Z, Li H, Liu G, Zhou Y, Luckhardt T, Bae S, Liu RM, Rangarajan S, de Andrade J, Thannickal VJ, Antony VB.

JCI Insight. 2017 Jan 26;2(2):e91377. doi: 10.1172/jci.insight.91377. Erratum in: JCI Insight. 2017 Apr 20;2(8):.

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