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Items: 1 to 20 of 21

1.

Inhibition of Inositol kinase B controls acute and chronic graft-versus-host disease.

Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, Murphy WJ, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Dahlberg C, Miller AT, Blazar BR.

Blood. 2019 Oct 15. pii: blood.2019000032. doi: 10.1182/blood.2019000032. [Epub ahead of print]

PMID:
31697815
2.

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality.

Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR.

JCI Insight. 2019 Oct 3;4(19). pii: 127716. doi: 10.1172/jci.insight.127716.

3.

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD.

Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR.

Blood. 2019 Nov 7;134(19):1670-1682. doi: 10.1182/blood.2019001950.

PMID:
31533918
4.

Achievement of Tolerance Induction to Prevent Acute Graft-vs.-Host Disease.

Thangavelu G, Blazar BR.

Front Immunol. 2019 Mar 6;10:309. doi: 10.3389/fimmu.2019.00309. eCollection 2019. Review.

5.

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality.

Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR.

J Immunol. 2019 May 1;202(9):2795-2805. doi: 10.4049/jimmunol.1800899. Epub 2019 Mar 18.

PMID:
30885956
6.

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease.

McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, Kirchmeier AK, Osborn MJ, Hippen KL, Kelekar A, Serody JS, Turka LA, Munn DH, Chi H, Neubert TA, Dustin ML, Blazar BR.

J Clin Invest. 2018 Oct 1;128(10):4604-4621. doi: 10.1172/JCI95713. Epub 2018 Aug 14.

7.

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice.

Pennell CA, Barnum JL, McDonald-Hyman CS, Panoskaltsis-Mortari A, Riddle MJ, Xiong Z, Loschi M, Thangavelu G, Campbell HM, Storlie MD, Refaeli Y, Furlan SN, Jensen MC, Kean LS, Miller JS, Tolar J, Osborn MJ, Blazar BR.

Mol Ther. 2018 Jun 6;26(6):1423-1434. doi: 10.1016/j.ymthe.2018.04.006. Epub 2018 Apr 7.

8.

Prior to Peripheral Tolerance, Newly Generated CD4 T Cells Maintain Dangerous Autoimmune Potential: Fas- and Perforin-Independent Autoimmunity Controlled by Programmed Death-1.

Ellestad KK, Thangavelu G, Haile Y, Lin J, Boon L, Anderson CC.

Front Immunol. 2018 Jan 24;9:12. doi: 10.3389/fimmu.2018.00012. eCollection 2018.

9.

Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells.

Du J, Paz K, Thangavelu G, Schneidawind D, Baker J, Flynn R, Duramad O, Feser C, Panoskaltsis-Mortari A, Negrin RS, Blazar BR.

Blood. 2017 Jun 8;129(23):3121-3125. doi: 10.1182/blood-2016-11-752444. Epub 2017 Apr 17.

10.

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR.

J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13.

11.

PD-1 is not required for natural or peripherally induced regulatory T cells: Severe autoimmunity despite normal production of regulatory T cells.

Ellestad KK, Thangavelu G, Ewen CL, Boon L, Anderson CC.

Eur J Immunol. 2014 Dec;44(12):3560-72. doi: 10.1002/eji.201444688. Epub 2014 Oct 27.

12.

Control of in vivo collateral damage generated by T cell immunity.

Thangavelu G, Gill RG, Boon L, Ellestad KK, Anderson CC.

J Immunol. 2013 Aug 15;191(4):1686-91. doi: 10.4049/jimmunol.1203240. Epub 2013 Jul 12.

13.

An essential role for programmed death-1 in the control of autoimmunity: implications for the future of hematopoietic stem cell transplantation.

Thangavelu G, Anderson CC.

Future Oncol. 2011 Aug;7(8):929-32. doi: 10.2217/fon.11.68. No abstract available.

14.
15.

Co-inhibitory molecules: Controlling the effectors or controlling the controllers?

Thangavelu G, Smolarchuk C, Anderson CC.

Self Nonself. 2010 Apr;1(2):77-88. Epub 2010 Feb 16.

16.

Programmed death-1 is required for systemic self-tolerance in newly generated T cells during the establishment of immune homeostasis.

Thangavelu G, Parkman JC, Ewen CL, Uwiera RR, Baldwin TA, Anderson CC.

J Autoimmun. 2011 May;36(3-4):301-12. doi: 10.1016/j.jaut.2011.02.009. Epub 2011 Mar 26.

17.

The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants.

Thangavelu G, Murphy KM, Yagita H, Boon L, Anderson CC.

Immunobiology. 2011 Aug;216(8):918-24. doi: 10.1016/j.imbio.2011.01.007. Epub 2011 Jan 12.

18.

BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice.

Truong W, Hancock WW, Plester JC, Merani S, Rayner DC, Thangavelu G, Murphy KM, Anderson CC, Shapiro AM.

J Leukoc Biol. 2009 Jul;86(1):41-51. doi: 10.1189/jlb.1107753. Epub 2009 Apr 21.

PMID:
19383625
19.
20.

Atypical angiofibroma of larynx - a case report.

Renukananda GS, Basavaraja PK, Naik AS, Maheshwari M, Balaji NK, Thangavelu G.

Indian J Otolaryngol Head Neck Surg. 2008 Mar;60(1):51-2. doi: 10.1007/s12070-008-0016-y. Epub 2008 Apr 3.

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