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Items: 11

1.

Parallel signaling through IRE1α and PERK regulates pancreatic neuroendocrine tumor growth and survival.

Moore PC, Qi JY, Thamsen M, Ghosh R, Peng J, Gliedt MJ, Meza-Acevedo R, Warren RE, Hiniker A, Kim GE, Maly DJ, Backes BJ, Papa FR, Oakes SA.

Cancer Res. 2019 Oct 31. pii: canres.1116.2019. doi: 10.1158/0008-5472.CAN-19-1116. [Epub ahead of print]

PMID:
31672843
2.

Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays.

Hardwick RN, Betts CJ, Whritenour J, Sura R, Thamsen M, Kaufman EH, Fabre K.

Lab Chip. 2019 Oct 10. doi: 10.1039/c9lc00519f. [Epub ahead of print]

PMID:
31598618
3.

Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung.

Thamsen M, Ghosh R, Auyeung VC, Brumwell A, Chapman HA, Backes BJ, Perara G, Maly DJ, Sheppard D, Papa FR.

PLoS One. 2019 Jan 9;14(1):e0209824. doi: 10.1371/journal.pone.0209824. eCollection 2019.

4.

Folding Optimization In Vivo Uncovers New Chaperones.

Lennon CW, Thamsen M, Friman ET, Cacciaglia A, Sachsenhauser V, Sorgenfrei FA, Wasik MA, Bardwell JC.

J Mol Biol. 2015 Sep 11;427(18):2983-94. doi: 10.1016/j.jmb.2015.05.013. Epub 2015 May 21.

5.

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.

Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C; Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK.

Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20.

6.

About the dangers, costs and benefits of living an aerobic lifestyle.

Knoefler D, Leichert LI, Thamsen M, Cremers CM, Reichmann D, Gray MJ, Wholey WY, Jakob U.

Biochem Soc Trans. 2014 Aug;42(4):917-21. doi: 10.1042/BST20140108. Review.

7.

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, Bhhatarai B, Schürer SC, Snapp EL, Gould DB, German MS, Backes BJ, Maly DJ, Oakes SA, Papa FR.

Cell. 2014 Jul 31;158(3):534-48. doi: 10.1016/j.cell.2014.07.002. Epub 2014 Jul 10.

8.

Quantitative in vivo redox sensors uncover oxidative stress as an early event in life.

Knoefler D, Thamsen M, Koniczek M, Niemuth NJ, Diederich AK, Jakob U.

Mol Cell. 2012 Sep 14;47(5):767-76. doi: 10.1016/j.molcel.2012.06.016. Epub 2012 Jul 19.

9.

The redoxome: Proteomic analysis of cellular redox networks.

Thamsen M, Jakob U.

Curr Opin Chem Biol. 2011 Feb;15(1):113-9. doi: 10.1016/j.cbpa.2010.11.013. Epub 2010 Dec 2. Review.

10.

Is overoxidation of peroxiredoxin physiologically significant?

Thamsen M, Kumsta C, Li F, Jakob U.

Antioxid Redox Signal. 2011 Feb 15;14(4):725-30. doi: 10.1089/ars.2010.3717. Epub 2010 Dec 17.

11.

Effects of oxidative stress on behavior, physiology, and the redox thiol proteome of Caenorhabditis elegans.

Kumsta C, Thamsen M, Jakob U.

Antioxid Redox Signal. 2011 Mar 15;14(6):1023-37. doi: 10.1089/ars.2010.3203. Epub 2010 Oct 28.

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