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Items: 1 to 50 of 79

1.
2.

Efficacy and safety of empagliflozin twice daily versus once daily in patients with type 2 diabetes inadequately controlled on metformin: a 16-week, randomized, placebo-controlled trial.

Ross S, Thamer C, Cescutti J, Meinicke T, Woerle HJ, Broedl UC.

Diabetes Obes Metab. 2015 Jul;17(7):699-702. doi: 10.1111/dom.12469. Epub 2015 May 13.

PMID:
25827441
3.

Sensitive troponins--which suits better for hemodialysis patients? Associated factors and prediction of mortality.

Artunc F, Mueller C, Breidthardt T, Twerenbold R, Peter A, Thamer C, Weyrich P, Haering HU, Friedrich B.

PLoS One. 2012;7(10):e47610. doi: 10.1371/journal.pone.0047610. Epub 2012 Oct 15.

4.

Active depression is associated with regional adiposity in the upper abdomen and the neck.

Ludescher B, Machann J, Eschweiler GW, Thamer C, Maenz C, Hipp A, Claussen CD, Schick F.

Int J Psychiatry Med. 2011;41(3):271-80.

PMID:
22073766
5.

In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors' insulin sensitivity in vivo.

Ordelheide AM, Heni M, Thamer C, Machicao F, Fritsche A, Stefan N, Häring HU, Staiger H.

Eur J Clin Invest. 2011 Dec;41(12):1323-9. doi: 10.1111/j.1365-2362.2011.02547.x. Epub 2011 May 25.

PMID:
21615395
6.

Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention.

Totsikas C, Röhm J, Kantartzis K, Thamer C, Rittig K, Machann J, Schick F, Hansel J, Niess A, Fritsche A, Häring HU, Stefan N.

J Hypertens. 2011 Jun;29(6):1220-7. doi: 10.1097/HJH.0b013e3283469910.

PMID:
21505353
7.

Insulin sensitivity and liver fat: role of iron load.

Haap M, Machann J, von Friedeburg C, Schick F, Stefan N, Schwenzer NF, Fritsche A, Häring HU, Thamer C.

J Clin Endocrinol Metab. 2011 Jun;96(6):E958-61. doi: 10.1210/jc.2010-2682. Epub 2011 Mar 23.

PMID:
21430023
8.

Apelin serum levels are not associated with early atherosclerosis or fat distribution in young subjects with increased risk for type 2 diabetes.

Rittig K, Hildebrandt U, Thamer C, Staiger H, Peter A, Stefan N, Fritsche A, Häring HU, Balletshofer BM, Siegel-Axel D.

Exp Clin Endocrinol Diabetes. 2011 Jun;119(6):358-61. doi: 10.1055/s-0030-1268466. Epub 2011 Jan 24.

PMID:
21264801
9.

Morning to evening changes of intramyocellular lipid content in dependence on nutrition and physical activity during one single day: a volume selective 1H-MRS study.

Machann J, Etzel M, Thamer C, Haring HU, Claussen CD, Fritsche A, Schick F.

MAGMA. 2011 Feb;24(1):29-33. doi: 10.1007/s10334-010-0233-8. Epub 2011 Jan 7.

PMID:
21213017
10.

Acute, short-term hyperinsulinemia increases olfactory threshold in healthy subjects.

Ketterer C, Heni M, Thamer C, Herzberg-Schäfer SA, Häring HU, Fritsche A.

Int J Obes (Lond). 2011 Aug;35(8):1135-8. doi: 10.1038/ijo.2010.251. Epub 2010 Nov 23.

PMID:
21102552
11.

The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia.

Heni M, Ketterer C, Hart LM, Ranta F, van Haeften TW, Eekhoff EM, Dekker JM, Boomsma DI, Nijpels G, Kramer MH, Diamant M, Simonis-Bik AM, Heine RJ, de Geus EJ, Schäfer SA, Machicao F, Ullrich S, Thamer C, Stefan N, Staiger H, Häring HU, Fritsche A.

J Clin Endocrinol Metab. 2010 Dec;95(12):E479-84. doi: 10.1210/jc.2010-0860. Epub 2010 Sep 8.

PMID:
20826583
12.

Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion.

Heni M, Ketterer C, Thamer C, Herzberg-Schäfer SA, Guthoff M, Stefan N, Machicao F, Staiger H, Fritsche A, Häring HU.

Diabetes. 2010 Dec;59(12):3247-52. doi: 10.2337/db10-0674. Epub 2010 Aug 29.

13.

Follow-up whole-body assessment of adipose tissue compartments during a lifestyle intervention in a large cohort at increased risk for type 2 diabetes.

Machann J, Thamer C, Stefan N, Schwenzer NF, Kantartzis K, Häring HU, Claussen CD, Fritsche A, Schick F.

Radiology. 2010 Nov;257(2):353-63. doi: 10.1148/radiol.10092284. Epub 2010 Aug 16.

PMID:
20713612
14.

Reducing visceral adipose tissue mass is essential for improving endothelial function in type 2 diabetes prone individuals.

Rittig K, Hieronimus A, Thamer C, Machann J, Peter A, Stock J, Schick F, Fritsche A, Stefan N, Häring HU, Balletshofer B.

Atherosclerosis. 2010 Oct;212(2):575-9. doi: 10.1016/j.atherosclerosis.2010.06.042. Epub 2010 Jul 8.

PMID:
20667538
15.

Interscapular fat is strongly associated with insulin resistance.

Thamer C, Machann J, Staiger H, Müssig K, Schwenzer N, Ludescher B, Machicao F, Claussen C, Fritsche A, Schick F, Stefan N, Häring HU.

J Clin Endocrinol Metab. 2010 Oct;95(10):4736-42. doi: 10.1210/jc.2009-1942. Epub 2010 Jul 21.

PMID:
20660049
16.

Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.

Heni M, Haupt A, Schäfer SA, Ketterer C, Thamer C, Machicao F, Stefan N, Staiger H, Häring HU, Fritsche A.

BMC Med Genet. 2010 Jun 9;11:86. doi: 10.1186/1471-2350-11-86.

17.

The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention.

Müssig K, Heni M, Thamer C, Kantartzis K, Machicao F, Stefan N, Fritsche A, Häring HU, Staiger H.

Diabetologia. 2010 Mar;53(3):504-9. doi: 10.1007/s00125-009-1612-4. Epub 2009 Nov 29.

PMID:
20091022
18.

Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes.

Haupt A, Thamer C, Heni M, Ketterer C, Machann J, Schick F, Machicao F, Stefan N, Claussen CD, Häring HU, Fritsche A, Staiger H.

Diabetes. 2010 Mar;59(3):747-50. doi: 10.2337/db09-1050. Epub 2009 Dec 22.

19.

Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2010 Jun;18(6):1212-7. doi: 10.1038/oby.2009.413. Epub 2009 Nov 12.

20.

Correlation of fat distribution in whole body MRI with generally used anthropometric data.

Ludescher B, Machann J, Eschweiler GW, Vanhöfen S, Maenz C, Thamer C, Claussen CD, Schick F.

Invest Radiol. 2009 Nov;44(11):712-9. doi: 10.1097/RLI.0b013e3181afbb1e.

PMID:
19809346
21.

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention.

Thamer C, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes Care. 2009 Sep;32(9):e112. doi: 10.2337/dc09-0965. No abstract available.

PMID:
19717817
22.

Impact of variation near MC4R on whole-body fat distribution, liver fat, and weight loss.

Haupt A, Thamer C, Heni M, Tschritter O, Machann J, Schick F, Machicao F, Häring HU, Staiger H, Fritsche A.

Obesity (Silver Spring). 2009 Oct;17(10):1942-5. doi: 10.1038/oby.2009.233. Epub 2009 Jul 30.

23.

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population.

Rittig K, Thamer C, Haupt A, Machann J, Peter A, Balletshofer B, Fritsche A, Haring HU, Stefan N.

Atherosclerosis. 2009 Dec;207(2):341-2. doi: 10.1016/j.atherosclerosis.2009.05.018. Epub 2009 May 22. No abstract available.

PMID:
19615685
24.

Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo.

Peter A, Weigert C, Staiger H, Machicao F, Schick F, Machann J, Stefan N, Thamer C, Häring HU, Schleicher E.

Diabetes. 2009 Aug;58(8):1757-65. doi: 10.2337/db09-0188. Epub 2009 May 28.

25.

Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.

Boettcher M, Machann J, Stefan N, Thamer C, Häring HU, Claussen CD, Fritsche A, Schick F.

J Magn Reson Imaging. 2009 Jun;29(6):1340-5. doi: 10.1002/jmri.21754.

PMID:
19422021
26.

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.

Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Apr;58(4):519-24. doi: 10.1016/j.metabol.2008.11.011.

PMID:
19303973
27.

[A rare cause of hypoglycaemia in a patient with type 2 diabetes].

Heni M, Schott S, Horger M, Dudziak K, Thamer C, Häring HU, Fritsche A, Müssig K.

Dtsch Med Wochenschr. 2009;134 Suppl Falldatenbank:F2. doi: 10.1055/s-0028-1082826. Epub 2009 Feb 23. German.

PMID:
19235687
28.

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. doi: 10.1210/jc.2008-1048. Epub 2009 Jan 13.

PMID:
19141580
29.

High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.

Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, Königsrainer A, Königsrainer I, Kröber S, Niess A, Fritsche A, Häring HU, Stefan N.

Gut. 2009 Sep;58(9):1281-8. doi: 10.1136/gut.2008.151977. Epub 2008 Dec 11.

PMID:
19074179
30.

Variation in the FTO gene influences food intake but not energy expenditure.

Haupt A, Thamer C, Staiger H, Tschritter O, Kirchhoff K, Machicao F, Häring HU, Stefan N, Fritsche A.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):194-7. doi: 10.1055/s-0028-1087176. Epub 2008 Dec 3.

PMID:
19053021
31.

Identification and characterization of metabolically benign obesity in humans.

Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, Rittig K, Balletshofer B, Machicao F, Fritsche A, Häring HU.

Arch Intern Med. 2008 Aug 11;168(15):1609-16. doi: 10.1001/archinte.168.15.1609.

PMID:
18695074
32.

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.

Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, Machicao F, Schick F, Häring HU, Fritsche A.

Obesity (Silver Spring). 2008 Aug;16(8):1969-72. doi: 10.1038/oby.2008.283. Epub 2008 May 29.

33.

Liver enzymes and incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.

Ford ES, Schulze MB, Bergmann MM, Thamer C, Joost HG, Boeing H.

Diabetes Care. 2008 Jun;31(6):1138-43. doi: 10.2337/dc07-2159. Epub 2008 Mar 17.

PMID:
18346992
34.

Variations in PPARD determine the change in body composition during lifestyle intervention: a whole-body magnetic resonance study.

Thamer C, Machann J, Stefan N, Schäfer SA, Machicao F, Staiger H, Laakso M, Böttcher M, Claussen C, Schick F, Fritsche A, Haring HU.

J Clin Endocrinol Metab. 2008 Apr;93(4):1497-500. doi: 10.1210/jc.2007-1209. Epub 2008 Feb 5.

PMID:
18252792
35.

Symptomatic hypoglycemia during imatinib mesylate in a non-diabetic female patient with gastrointestinal stromal tumor.

Haap M, Gallwitz B, Thamer C, Müssig K, Häring HU, Kanz L, Hartmann JT.

J Endocrinol Invest. 2007 Sep;30(8):688-92.

PMID:
17923802
36.

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

Staiger H, Machicao F, Stefan N, Tschritter O, Thamer C, Kantartzis K, Schäfer SA, Kirchhoff K, Fritsche A, Häring HU.

PLoS One. 2007 Sep 5;2(9):e832.

37.

Impact of different fat depots on insulin sensitivity: predominant role of liver fat.

Kirchhoff K, Kantartzis K, Machann J, Schick F, Thamer C, Machicao F, Fritsche A, Häring HU, Stefan N.

J Diabetes Sci Technol. 2007 Sep;1(5):753-9.

38.

Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites.

Weyrich P, Machicao F, Staiger H, Simon P, Thamer C, Machann J, Schick F, Guirguis A, Fritsche A, Stefan N, Häring HU.

Diabetologia. 2007 Oct;50(10):2097-106. Epub 2007 Aug 14.

PMID:
17701023
39.

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

Schäfer SA, Tschritter O, Machicao F, Thamer C, Stefan N, Gallwitz B, Holst JJ, Dekker JM, 't Hart LM, Nijpels G, van Haeften TW, Häring HU, Fritsche A.

Diabetologia. 2007 Dec;50(12):2443-50. Epub 2007 Jul 28. Erratum in: Diabetologia. 2008 Jan;51(1):208. t' Hart, L M [corrected to 't Hart, L M]. Diabetologia. 2009 Mar;52(3):557. Dosage error in article text.

40.

Gender specific correlations of adrenal gland size and body fat distribution: a whole body MRI study.

Ludescher B, Najib A, Baar S, Machann J, Thamer C, Schick F, Buchkremer G, Claussen CD, Eschweiler GW.

Horm Metab Res. 2007 Jul;39(7):515-8.

PMID:
17611905
41.

[Gene-environment interactions in the pathogenesis and prevention of type 2 diabetes mellitus].

Fritsche A, Thamer C, Stefan N, Häring HU.

Internist (Berl). 2007 Jul;48(7):669-70, 672, 674-5. Review. German.

PMID:
17541530
42.

The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.

Rittig K, Thamer C, Machicao F, Rietig R, Stefan N, Fritsche A, Haring HU, Balletshofer B.

Diabetologia. 2007 Jun;50(6):1345-7. Epub 2007 Apr 6. No abstract available.

PMID:
17415545
43.

Hypomagnesemia and nephrocalcinosis in a patient with two heterozygous mutations in the CLDN16 gene.

Staiger K, Staiger H, Haas C, Thamer C, Risler T, Machicao F, Häring HU.

J Nephrol. 2007 Jan-Feb;20(1):107-10.

PMID:
17347984
44.

Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.

Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, Venter C, Niess A, Laakso M, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2007 May;92(5):1827-33. Epub 2007 Feb 27.

PMID:
17327385
45.

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes.

Schulze MB, Hoffmann K, Boeing H, Linseisen J, Rohrmann S, Möhlig M, Pfeiffer AF, Spranger J, Thamer C, Häring HU, Fritsche A, Joost HG.

Diabetes Care. 2007 Mar;30(3):510-5.

PMID:
17327313
46.

High visceral fat mass and high liver fat are associated with resistance to lifestyle intervention.

Thamer C, Machann J, Stefan N, Haap M, Schäfer S, Brenner S, Kantartzis K, Claussen C, Schick F, Haring H, Fritsche A.

Obesity (Silver Spring). 2007 Feb;15(2):531-8.

47.

Iodine-induced thyrotoxicosis after ingestion of kelp-containing tea.

Müssig K, Thamer C, Bares R, Lipp HP, Häring HU, Gallwitz B.

J Gen Intern Med. 2006 Jun;21(6):C11-4.

48.

Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes.

Thamer C, Haap M, Heller E, Joel L, Braun S, Tschritter O, Haring H, Fritsche A.

Horm Metab Res. 2006 Mar;38(3):178-82.

PMID:
16673209
49.

Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy.

Machann J, Thamer C, Schnoedt B, Stefan N, Haring HU, Claussen CD, Fritsche A, Schick F.

Magn Reson Med. 2006 Apr;55(4):913-7.

50.

New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity.

Stefan N, Machann J, Schick F, Claussen CD, Thamer C, Fritsche A, Häring HU.

Horm Res. 2005;64 Suppl 3:38-44. Epub 2006 Jan 20. Review.

PMID:
16439843

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