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Items: 1 to 50 of 124

1.

Metabolism of Estrogens: Turnover Differs Between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells.

Poschner S, Wackerlig J, Castillo-Tong DC, Wolf A, Decken IV, Rižner TL, Pavlič R, Meshcheryakova A, Mechtcheriakova D, Fritzer-Szekeres M, Thalhammer T, Jäger W.

Cancers (Basel). 2020 Jan 23;12(2). pii: E279. doi: 10.3390/cancers12020279.

2.

Future Aspects for Cannabinoids in Breast Cancer Therapy.

Kisková T, Mungenast F, Suváková M, Jäger W, Thalhammer T.

Int J Mol Sci. 2019 Apr 3;20(7). pii: E1673. doi: 10.3390/ijms20071673. Review.

3.

Resveratrol and other dietary polyphenols are inhibitors of estrogen metabolism in human breast cancer cells.

Poschner S, Maier-Salamon A, Thalhammer T, Jäger W.

J Steroid Biochem Mol Biol. 2019 Jun;190:11-18. doi: 10.1016/j.jsbmb.2019.03.001. Epub 2019 Mar 6. Review.

PMID:
30851384
4.

Clinical Significance of Organic Anion Transporting Polypeptide Gene Expression in High-Grade Serous Ovarian Cancer.

Svoboda M, Mungenast F, Gleiss A, Vergote I, Vanderstichele A, Sehouli J, Braicu E, Mahner S, Jäger W, Mechtcheriakova D, Cacsire-Tong D, Zeillinger R, Thalhammer T, Pils D.

Front Pharmacol. 2018 Aug 7;9:842. doi: 10.3389/fphar.2018.00842. eCollection 2018.

5.

Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation.

Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Meshcheryakova A, Mechtcheriakova D, Thalhammer T, Pachmann B, Jäger W.

Front Pharmacol. 2018 Jul 10;9:742. doi: 10.3389/fphar.2018.00742. eCollection 2018.

6.

Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse.

Buxhofer-Ausch V, Sheikh M, Ausch C, Zotter S, Bauer H, Mollik M, Reiner A, Gleiss A, Jäger W, Sebesta C, Kriwanek S, Thalhammer T.

Appl Immunohistochem Mol Morphol. 2019 Mar;27(3):185-194. doi: 10.1097/PAI.0000000000000557.

PMID:
29734253
7.

Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats.

Kiskova T, Demeckova V, Jendzelovska Z, Kiktava M, Venglovska K, Bohmdorfer M, Jager W, Thalhammer T.

J Physiol Pharmacol. 2017 Dec;68(6):867-875.

8.

Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice.

Böhmdorfer M, Szakmary A, Schiestl RH, Vaquero J, Riha J, Brenner S, Thalhammer T, Szekeres T, Jäger W.

Nutrients. 2017 Dec 12;9(12). pii: E1347. doi: 10.3390/nu9121347.

9.

Pharmacokinetics of flucloxacillin and its metabolites in patients with renal failure: Impact on liver toxicity
.

Maier-Salamon A, Elgendy SA, Meyer B, Vossen M, Thalhammer T, Thalhammer F, Jäger W.

Int J Clin Pharmacol Ther. 2017 Sep;55(9):701-711. doi: 10.5414/CP202796.

PMID:
28737131
10.

The Importance of Steroid Uptake and Intracrine Action in Endometrial and Ovarian Cancers.

Rižner TL, Thalhammer T, Özvegy-Laczka C.

Front Pharmacol. 2017 Jun 19;8:346. doi: 10.3389/fphar.2017.00346. eCollection 2017. Review.

11.

Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer.

Mungenast F, Aust S, Vergote I, Vanderstichele A, Sehouli J, Braicu E, Mahner S, Castillo-Tong DC, Zeillinger R, Thalhammer T.

Oncol Lett. 2017 Jun;13(6):4047-4054. doi: 10.3892/ol.2017.5969. Epub 2017 Apr 3.

12.

AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.

Svoboda M, Meshcheryakova A, Heinze G, Jaritz M, Pils D, Castillo-Tong DC, Hager G, Thalhammer T, Jensen-Jarolim E, Birner P, Braicu I, Sehouli J, Lambrechts S, Vergote I, Mahner S, Zimmermann P, Zeillinger R, Mechtcheriakova D.

BMC Genomics. 2016 Aug 16;17(1):643. doi: 10.1186/s12864-016-3001-y.

13.

Quantitative Image Analysis of Epithelial and Stromal Area in Histological Sections of Colorectal Cancer: An Emerging Diagnostic Tool.

Rogojanu R, Thalhammer T, Thiem U, Heindl A, Mesteri I, Seewald A, Jäger W, Smochina C, Ellinger I, Bises G.

Biomed Res Int. 2015;2015:569071. doi: 10.1155/2015/569071. Epub 2015 Oct 22.

14.

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

Riha J, Brenner S, Srovnalova A, Klameth L, Dvorak Z, Jäger W, Thalhammer T.

Food Funct. 2015 Mar;6(3):772-9. doi: 10.1039/c4fo00977k.

PMID:
25578040
15.

Estrogen biosynthesis and action in ovarian cancer.

Mungenast F, Thalhammer T.

Front Endocrinol (Lausanne). 2014 Nov 12;5:192. doi: 10.3389/fendo.2014.00192. eCollection 2014. Review.

16.

The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells.

Brenner S, Riha J, Giessrigl B, Thalhammer T, Grusch M, Krupitza G, Stieger B, Jäger W.

Int J Oncol. 2015 Jan;46(1):324-32. doi: 10.3892/ijo.2014.2731. Epub 2014 Oct 24.

PMID:
25351763
17.

Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy.

Brenner S, Klameth L, Riha J, Schölm M, Hamilton G, Bajna E, Ausch C, Reiner A, Jäger W, Thalhammer T, Buxhofer-Ausch V.

Cancer Lett. 2015 Jan 28;356(2 Pt B):517-24. doi: 10.1016/j.canlet.2014.09.025. Epub 2014 Oct 6.

PMID:
25301452
18.

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats.

Kisková T, Jendželovský R, Rentsen E, Maier-Salamon A, Kokošová N, Papčová Z, Mikeš J, Orendáš P, Bojková B, Kubatka P, Svoboda M, Kajo K, Fedoročko P, Jäger W, Ekmekcioglu C, Kassayová M, Thalhammer T.

Eur J Cancer Prev. 2014 Nov;23(6):506-13. doi: 10.1097/CEJ.0000000000000083. Erratum in: Eur J Cancer Prev. 2015 Mar;24(2):165.

PMID:
25254309
19.

Decreased melatonin levels and increased levels of advanced oxidation protein products in the seminal plasma are related to male infertility.

Kratz EM, Piwowar A, Zeman M, Stebelová K, Thalhammer T.

Reprod Fertil Dev. 2016 Mar;28(4):507-15. doi: 10.1071/RD14165.

PMID:
25218686
20.

Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.

Riha J, Brenner S, Böhmdorfer M, Giessrigl B, Pignitter M, Schueller K, Thalhammer T, Stieger B, Somoza V, Szekeres T, Jäger W.

Mol Nutr Food Res. 2014 Sep;58(9):1830-42. doi: 10.1002/mnfr.201400095. Epub 2014 Jul 3.

PMID:
24996158
21.

Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: impact on cancer therapy.

Maier-Salamon A, Thalhammer T, Reznicek G, Böhmdorfer M, Zupkó I, Hartl A, Jaeger W.

Int J Oncol. 2014 Aug;45(2):877-86. doi: 10.3892/ijo.2014.2473. Epub 2014 May 29.

PMID:
24889073
22.

Synergism of cyclin-dependent kinase inhibitors with camptothecin derivatives in small cell lung cancer cell lines.

Hamilton G, Klameth L, Rath B, Thalhammer T.

Molecules. 2014 Feb 17;19(2):2077-88. doi: 10.3390/molecules19022077.

23.

Novel oncology therapeutics: targeted drug delivery for cancer.

Tzakos AG, Briasoulis E, Thalhammer T, Jäger W, Apostolopoulos V.

J Drug Deliv. 2013;2013:918304. doi: 10.1155/2013/918304. Epub 2013 Oct 22. No abstract available.

24.

Targeting antigens to dendritic cell receptors for vaccine development.

Apostolopoulos V, Thalhammer T, Tzakos AG, Stojanovska L.

J Drug Deliv. 2013;2013:869718. doi: 10.1155/2013/869718. Epub 2013 Oct 8. Review.

25.

Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients--a study of the OVCAD consortium.

Bachmayr-Heyda A, Aust S, Heinze G, Polterauer S, Grimm C, Braicu EI, Sehouli J, Lambrechts S, Vergote I, Mahner S, Pils D, Schuster E, Thalhammer T, Horvat R, Denkert C, Zeillinger R, Castillo-Tong DC.

BMC Cancer. 2013 Sep 17;13:422. doi: 10.1186/1471-2407-13-422.

26.

Interplay between metabolism and transport of resveratrol.

Maier-Salamon A, Böhmdorfer M, Riha J, Thalhammer T, Szekeres T, Jaeger W.

Ann N Y Acad Sci. 2013 Jul;1290:98-106. doi: 10.1111/nyas.12198. Review.

PMID:
23855471
27.

Determination of tumor-infiltrating CD8+ lymphocytes in human ovarian cancer.

Aust S, Bachmayr-Heyda A, Pils D, Zhao L, Tong W, Berger A, Fogel M, Thalhammer T, Sehouli J, Horvat R, Zeillinger R, Castillo-Tong DC.

Int J Gynecol Pathol. 2013 May;32(3):269-76. doi: 10.1097/PGP.0b013e31826a63f8.

PMID:
23518910
28.

The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors.

Secky L, Svoboda M, Klameth L, Bajna E, Hamilton G, Zeillinger R, Jäger W, Thalhammer T.

J Drug Deliv. 2013;2013:957605. doi: 10.1155/2013/957605. Epub 2013 Feb 13.

29.

Tumor-specific expression of organic anion-transporting polypeptides: transporters as novel targets for cancer therapy.

Buxhofer-Ausch V, Secky L, Wlcek K, Svoboda M, Kounnis V, Briasoulis E, Tzakos AG, Jaeger W, Thalhammer T.

J Drug Deliv. 2013;2013:863539. doi: 10.1155/2013/863539. Epub 2013 Feb 3.

30.

Automated REcognition of tissue-associated erythrocytes (ARETE)-a new tool in tissue cytometry.

Heindl A, Seewald AK, Thalhammer T, Bises G, Schepelmann M, Uhrova H, Dekan S, Mesteri I, Rogojanu R, Ellinger I.

Cytometry A. 2013 Apr;83(4):363-74. doi: 10.1002/cyto.a.22258. Epub 2013 Feb 11.

31.

Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas.

Nemeth C, Humpeler S, Kallay E, Mesteri I, Svoboda M, Rögelsperger O, Klammer N, Thalhammer T, Ekmekcioglu C.

J Biol Regul Homeost Agents. 2011 Oct-Dec;25(4):531-42.

PMID:
22217986
32.

A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.

Kisková T, Ekmekcioglu C, Garajová M, Orendáš P, Bojková B, Bobrov N, Jäger W, Kassayová M, Thalhammer T.

Eur J Cancer Prev. 2012 Mar;21(2):163-70. doi: 10.1097/CEJ.0b013e32834c9c0f.

PMID:
22044852
33.

A food matrix reduces digestion and absorption of food allergens in vivo.

Schulten V, Lauer I, Scheurer S, Thalhammer T, Bohle B.

Mol Nutr Food Res. 2011 Oct;55(10):1484-91. doi: 10.1002/mnfr.201100234. Epub 2011 Aug 30.

PMID:
21984443
34.

Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions.

Schmid D, Svoboda M, Sorgner A, Moravcevic I, Thalhammer T, Chiba P, Möslinger T.

Life Sci. 2011 Nov 7;89(19-20):725-34. doi: 10.1016/j.lfs.2011.08.017. Epub 2011 Sep 10.

PMID:
21925514
35.

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

Svoboda M, Wlcek K, Taferner B, Hering S, Stieger B, Tong D, Zeillinger R, Thalhammer T, Jäger W.

Biomed Pharmacother. 2011 Sep;65(6):417-26. doi: 10.1016/j.biopha.2011.04.031. Epub 2011 Jun 12.

36.

Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets.

Kounnis V, Ioachim E, Svoboda M, Tzakos A, Sainis I, Thalhammer T, Steiner G, Briasoulis E.

Onco Targets Ther. 2011 Apr 8;4:27-32. doi: 10.2147/OTT.S16706.

37.

Hepatic glucuronidation of resveratrol: interspecies comparison of enzyme kinetic profiles in human, mouse, rat, and dog.

Maier-Salamon A, Böhmdorfer M, Thalhammer T, Szekeres T, Jaeger W.

Drug Metab Pharmacokinet. 2011;26(4):364-73. Epub 2011 Apr 22.

38.

In vitro metabolism and disposition of honokiol in rat and human livers.

Böhmdorfer M, Maier-Salamon A, Taferner B, Reznicek G, Thalhammer T, Hering S, Hüfner A, Schühly W, Jäger W.

J Pharm Sci. 2011 Aug;100(8):3506-3516. doi: 10.1002/jps.22536. Epub 2011 Mar 14.

PMID:
21404278
39.

Organic anion transporting polypeptides (OATPs): regulation of expression and function.

Svoboda M, Riha J, Wlcek K, Jaeger W, Thalhammer T.

Curr Drug Metab. 2011 Feb;12(2):139-53. Review.

PMID:
21395542
40.

Melatonin receptors, melatonin metabolizing enzymes and cyclin D1 in human breast cancer.

Rögelsperger O, Wlcek K, Ekmekcioglu C, Humpeler S, Svoboda M, Königsberg R, Klimpfinger M, Jäger W, Thalhammer T.

J Recept Signal Transduct Res. 2011 Apr;31(2):180-7. doi: 10.3109/10799893.2011.557734.

PMID:
21385053
41.

The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer.

Wlcek K, Svoboda M, Riha J, Zakaria S, Olszewski U, Dvorak Z, Sellner F, Ellinger I, Jäger W, Thalhammer T.

Cancer Biol Ther. 2011 May 1;11(9):801-11. Epub 2011 May 1.

PMID:
21383546
42.

Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro.

Olszewski U, Liedauer R, Ausch C, Thalhammer T, Hamilton G.

Cancers (Basel). 2011 Mar 22;3(1):1467-79. doi: 10.3390/cancers3011467.

43.

Organic Anion Transporting Polypeptide 5A1 (OATP5A1) in Small Cell Lung Cancer (SCLC) Cells: Possible Involvement in Chemoresistance to Satraplatin.

Olszewski-Hamilton U, Svoboda M, Thalhammer T, Buxhofer-Ausch V, Geissler K, Hamilton G.

Biomark Cancer. 2011 Jun 7;3:31-40. doi: 10.4137/BIC.S7151. eCollection 2011.

44.

Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.

Obmann A, Tsendayush D, Thalhammer T, Zehl M, Vo TP, Purevsuren S, Natsagdorj D, Narantuya S, Kletter C, Glasl S.

J Ethnopharmacol. 2010 Oct 5;131(3):555-61. doi: 10.1016/j.jep.2010.07.029. Epub 2010 Jul 23.

PMID:
20656004
45.

Microarray analysis identifies distinct gene expression profiles associated with histological subtype in human osteosarcoma.

Kubista B, Klinglmueller F, Bilban M, Pfeiffer M, Lass R, Giurea A, Funovics PT, Toma C, Dominkus M, Kotz R, Thalhammer T, Trieb K, Zettl T, Singer CF.

Int Orthop. 2011 Mar;35(3):401-11. doi: 10.1007/s00264-010-0996-6. Epub 2010 Mar 26.

46.

Steroid hormone metabolizing enzymes in benign and malignant human bone tumors.

Svoboda M, Hamilton G, Thalhammer T.

Expert Opin Drug Metab Toxicol. 2010 Apr;6(4):427-37. doi: 10.1517/17425251003592129. Review.

PMID:
20102288
47.

Time dependence of estrogen receptor expression in human hearts.

Leibetseder V, Humpeler S, Zuckermann A, Svoboda M, Thalhammer T, Marktl W, Ekmekcioglu C.

Biomed Pharmacother. 2010 Mar;64(3):154-9. doi: 10.1016/j.biopha.2009.09.010. Epub 2009 Nov 5.

PMID:
19944560
48.

Aqueous extracts of Cimicifuga racemosa and phenolcarboxylic constituents inhibit production of proinflammatory cytokines in LPS-stimulated human whole blood.

Schmid D, Woehs F, Svoboda M, Thalhammer T, Chiba P, Moeslinger T.

Can J Physiol Pharmacol. 2009 Nov;87(11):963-72. doi: 10.1139/y09-091.

PMID:
19935904
49.

Different expression patterns of organic anion transporting polypeptides in osteosarcomas, bone metastases and aneurysmal bone cysts.

Liedauer R, Svoboda M, Wlcek K, Arrich F, Jä W, Toma C, Thalhammer T.

Oncol Rep. 2009 Dec;22(6):1485-92.

PMID:
19885603
50.

Expression of sulfotransferases and sulfatases in human breast cancer: impact on resveratrol metabolism.

Miksits M, Wlcek K, Svoboda M, Thalhammer T, Ellinger I, Stefanzl G, Falany CN, Szekeres T, Jaeger W.

Cancer Lett. 2010 Mar 28;289(2):237-45. doi: 10.1016/j.canlet.2009.08.020. Epub 2009 Sep 10.

PMID:
19747768

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