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Items: 1 to 50 of 70

1.

Adipose Tissue and Modulation of Hypertension.

Das E, Moon JH, Lee JH, Thakkar N, Pausova Z, Sung HK.

Curr Hypertens Rep. 2018 Sep 18;20(11):96. doi: 10.1007/s11906-018-0894-7. Review.

PMID:
30229358
2.

Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial.

Thakkar N, Green JA, Koh GCKW, Duparc S, Tenero D, Goyal N.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00711-18. doi: 10.1128/AAC.00711-18. Print 2018 Nov.

3.

Cross-associations between physical activity and sedentary time on metabolic health: a comparative assessment using self-reported and objectively measured activity.

Thakkar N, Jamnik V, Ardern CI.

J Public Health (Oxf). 2018 Apr 5. doi: 10.1093/pubmed/fdy060. [Epub ahead of print]

PMID:
29659929
4.

An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye.

Jaishankar D, Yakoub AM, Yadavalli T, Agelidis A, Thakkar N, Hadigal S, Ames J, Shukla D.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaan5861. doi: 10.1126/scitranslmed.aan5861.

PMID:
29444978
5.

Targeting Herpes Simplex Virus-1 gD by a DNA Aptamer Can Be an Effective New Strategy to Curb Viral Infection.

Yadavalli T, Agelidis A, Jaishankar D, Mangano K, Thakkar N, Penmetcha K, Shukla D.

Mol Ther Nucleic Acids. 2017 Dec 15;9:365-378. doi: 10.1016/j.omtn.2017.10.009. Epub 2017 Oct 17.

6.

Structure-based methods to predict mutational resistance to diarylpyrimidine non-nucleoside reverse transcriptase inhibitors.

Azeem SM, Muwonge AN, Thakkar N, Lam KW, Frey KM.

J Mol Graph Model. 2018 Jan;79:133-139. doi: 10.1016/j.jmgm.2017.10.023. Epub 2017 Nov 9.

PMID:
29156381
7.

Sculpting Fano Resonances To Control Photonic-Plasmonic Hybridization.

Thakkar N, Rea MT, Smith KC, Heylman KD, Quillin SC, Knapper KA, Horak EH, Masiello DJ, Goldsmith RH.

Nano Lett. 2017 Nov 8;17(11):6927-6934. doi: 10.1021/acs.nanolett.7b03332. Epub 2017 Oct 10.

PMID:
28968499
8.

Emerging Roles of Heparanase in Viral Pathogenesis.

Thakkar N, Yadavalli T, Jaishankar D, Shukla D.

Pathogens. 2017 Sep 18;6(3). pii: E43. doi: 10.3390/pathogens6030043. Review.

9.

Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia.

Thakkar N, Guptill JT, Aleš K, Jacobus D, Jacobus L, Peloquin C, Cohen-Wolkowiez M, Gonzalez D; DAPPER Study Group.

CPT Pharmacometrics Syst Pharmacol. 2017 Sep;6(9):625-634. doi: 10.1002/psp4.12218. Epub 2017 Jul 24.

10.

Evolution of circadian rhythms: from bacteria to human.

Bhadra U, Thakkar N, Das P, Pal Bhadra M.

Sleep Med. 2017 Jul;35:49-61. doi: 10.1016/j.sleep.2017.04.008. Epub 2017 May 8. Review.

PMID:
28619182
11.

Effect of Liver Disease on Hepatic Transporter Expression and Function.

Thakkar N, Slizgi JR, Brouwer KLR.

J Pharm Sci. 2017 Sep;106(9):2282-2294. doi: 10.1016/j.xphs.2017.04.053. Epub 2017 Apr 30. Review.

12.

Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.

Sissung TM, Ley AM, Strope JD, McCrea EM, Beedie S, Peer CJ, Shukla S, van Velkinburgh J, Reece K, Troutman S, Campbell T, Fernandez E, Huang P, Smith J, Thakkar N, Venzon DJ, Brenner S, Lee W, Merino M, Luo J, Jager W, Price DK, Chau CH, Figg WD.

Mol Cancer Res. 2017 Aug;15(8):1096-1105. doi: 10.1158/1541-7786.MCR-16-0477. Epub 2017 Apr 7.

13.

The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario.

Yen W, Hodwitz K, Thakkar N, Martimianakis MA, Faulkner D.

Can Med Educ J. 2016 Dec 5;7(3):e19-e30. eCollection 2016 Dec.

14.

The N-terminal region of organic anion transporting polypeptide 1B3 (OATP1B3) plays an essential role in regulating its plasma membrane trafficking.

Chun SE, Thakkar N, Oh Y, Park JE, Han S, Ryoo G, Hahn H, Maeng SH, Lim YR, Han BW, Lee W.

Biochem Pharmacol. 2017 May 1;131:98-105. doi: 10.1016/j.bcp.2017.02.013. Epub 2017 Feb 23.

PMID:
28216016
15.

Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells.

Thakkar N, Jaishankar D, Agelidis A, Yadavalli T, Mangano K, Patel S, Tekin SZ, Shukla D.

Sci Rep. 2017 Feb 15;7:42559. doi: 10.1038/srep42559.

16.

Metronidazole Induced Encephalopathy.

Thakkar N, Bhaarat, Chand R, Sharma R, Mahavar S, Srivastava S, Palawat A.

J Assoc Physicians India. 2016 Nov;64(11):72-74.

PMID:
27805338
17.

A case of coarctation of the abdominal aorta and renal artery stenosis due to neurofibromatosis type 1.

Veean S, Thakkar N, Gupta S, Keshavamurthy J.

Postgrad Med J. 2017 Apr;93(1098):235-236. doi: 10.1136/postgradmedj-2016-134460. Epub 2016 Oct 5. No abstract available.

PMID:
27708004
18.

STEM/EELS Imaging of Magnetic Hybridization in Symmetric and Symmetry-Broken Plasmon Oligomer Dimers and All-Magnetic Fano Interference.

Cherqui C, Wu Y, Li G, Quillin SC, Busche JA, Thakkar N, West CA, Montoni NP, Rack PD, Camden JP, Masiello DJ.

Nano Lett. 2016 Oct 12;16(10):6668-6676. Epub 2016 Sep 29.

19.

Clinical Pharmacology Studies in Critically Ill Children.

Thakkar N, Salerno S, Hornik CP, Gonzalez D.

Pharm Res. 2017 Jan;34(1):7-24. doi: 10.1007/s11095-016-2033-y. Epub 2016 Sep 1. Review.

20.

Antero-posterior Duplicate Exstrophy with a Wet Bladder Plate: A Diagnostic Dilemma.

Thakkar NC, Raj P, Sarin YK.

J Neonatal Surg. 2016 Jul 3;5(3):37. doi: 10.21699/jns.v5i3.369. eCollection 2016 Jul-Sep.

21.

Thoracoscopic excision of foregut duplication cyst: A case report and review of literature.

Sinha SK, Khanolkar A, Thakkar NC, Raj P, Kumar P, Bhalotra AR.

J Indian Assoc Pediatr Surg. 2016 Jul-Sep;21(3):147-9. doi: 10.4103/0971-9261.182591.

22.

Long non-coding RNA: Functional agent for disease traits.

Jain S, Thakkar N, Chhatai J, Pal Bhadra M, Bhadra U.

RNA Biol. 2017 May 4;14(5):522-535. doi: 10.1080/15476286.2016.1172756. Epub 2016 May 26. Review.

23.

Characterizing Localized Surface Plasmons Using Electron Energy-Loss Spectroscopy.

Cherqui C, Thakkar N, Li G, Camden JP, Masiello DJ.

Annu Rev Phys Chem. 2016 May 27;67:331-57. doi: 10.1146/annurev-physchem-040214-121612.

PMID:
27215817
24.

An opportunistic study evaluating pharmacokinetics of sildenafil for the treatment of pulmonary hypertension in infants.

Thakkar N, Gonzalez D, Cohen-Wolkowiez M, Massaro MM, Bernhardt J, Zane NR, Laughon MM.

J Perinatol. 2016 Sep;36(9):744-7. doi: 10.1038/jp.2016.79. Epub 2016 May 12.

25.

Depletion with Cyclodextrin Reveals Two Populations of Cholesterol in Model Lipid Membranes.

Litz JP, Thakkar N, Portet T, Keller SL.

Biophys J. 2016 Feb 2;110(3):635-645. doi: 10.1016/j.bpj.2015.11.021.

26.

Synchronous Ipsilateral Wilms' Tumor and Neuroblastoma in an Infant.

Sarin YK, Thakkar NC, Sinha S.

APSP J Case Rep. 2016 Jan 1;7(1):2. eCollection 2016 Jan-Apr.

27.

Extra-Renal Wilms' Tumor: A Rare Diagnosis.

Thakkar NC, Sarin YK.

APSP J Case Rep. 2015 May 1;6(2):17. eCollection 2015 May-Aug.

28.

Perils of total colonic aganglionosis presenting in neonatal age.

Yk S, P R, N T.

J Neonatal Surg. 2014 Jul 10;3(3):28. eCollection 2014 Jul-Sep.

29.

Differences in physical activity domains, guideline adherence, and weight history between metabolically healthy and metabolically abnormal obese adults: a cross-sectional study.

Kanagasabai T, Thakkar NA, Kuk JL, Churilla JR, Ardern CI.

Int J Behav Nutr Phys Act. 2015 May 16;12:64. doi: 10.1186/s12966-015-0227-z.

30.

Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy.

Thakkar N, Lockhart AC, Lee W.

AAPS J. 2015 May;17(3):535-45. doi: 10.1208/s12248-015-9740-x. Epub 2015 Mar 4. Review.

31.

Comparison of a self-inflating bulb syringe and a colorimetric CO2 indicator with capnography and radiography to detect the misdirection of naso/orogastric tubes into the airway of critically ill adult patients.

Smyrnios NA, Lenard R, Rajan S, Newman MS, Baker SP, Thakkar N, Wassef W, Ajmere NK, Irwin RS.

Chest. 2015 Jun;147(6):1523-1529. doi: 10.1378/chest.14-0663.

PMID:
25674721
32.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, Meier B, Gerstung M, Hong Y, Merino DM, Ramakrishna M, Remke M, Arnold R, Panigrahi GB, Thakkar NP, Hodel KP, Henninger EE, Göksenin AY, Bakry D, Charames GS, Druker H, Lerner-Ellis J, Mistry M, Dvir R, Grant R, Elhasid R, Farah R, Taylor GP, Nathan PC, Alexander S, Ben-Shachar S, Ling SC, Gallinger S, Constantini S, Dirks P, Huang A, Scherer SW, Grundy RG, Durno C, Aronson M, Gartner A, Meyn MS, Taylor MD, Pursell ZF, Pearson CE, Malkin D, Futreal PA, Stratton MR, Bouffet E, Hawkins C, Campbell PJ, Tabori U; Biallelic Mismatch Repair Deficiency Consortium.

Nat Genet. 2015 Mar;47(3):257-62. doi: 10.1038/ng.3202. Epub 2015 Feb 2.

PMID:
25642631
33.

Thymidylate synthase genotype-directed chemotherapy for patients with gastric and gastroesophageal junction cancers.

Goff LW, Thakkar N, Du L, Chan E, Tan BR, Cardin DB, McLeod HL, Berlin JD, Zehnbauer B, Fournier C, Picus J, Wang-Gillam A, Lee W, Lockhart AC.

PLoS One. 2014 Sep 18;9(9):e107424. doi: 10.1371/journal.pone.0107424. eCollection 2014.

34.

US and international health professions' requirements for continuing professional development.

Tran D, Tofade T, Thakkar N, Rouse M.

Am J Pharm Educ. 2014 Aug 15;78(6):129. doi: 10.5688/ajpe786129. Review.

35.

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.

Reddy K, Schmidt MH, Geist JM, Thakkar NP, Panigrahi GB, Wang YH, Pearson CE.

Nucleic Acids Res. 2014;42(16):10473-87. doi: 10.1093/nar/gku658. Epub 2014 Aug 21.

36.

Efficacy of insulin lispro in improving glycemic control in gestational diabetes.

Deepaklal MC, Joseph K, Kurian R, Thakkar NA.

Indian J Endocrinol Metab. 2014 Jul;18(4):491-5. doi: 10.4103/2230-8210.137492.

37.

A phase I study of pegylated liposomal doxorubicin and temsirolimus in patients with refractory solid malignancies.

Wang-Gillam A, Thakkar N, Lockhart AC, Williams K, Baggstrom M, Naughton M, Suresh R, Ma C, Tan B, Lee W, Jiang X, Mwandoro T, Trull L, Belanger S, Creekmore AN, Gao F, Fracasso PM, Picus J.

Cancer Chemother Pharmacol. 2014 Aug;74(2):419-26. doi: 10.1007/s00280-014-2493-x. Epub 2014 Jun 11.

38.

A sense of belonging.

Thakkar N.

Pa Dent J (Harrisb). 2014 Jan-Feb;81(1):23. No abstract available.

PMID:
24757927
39.

Charge-tunable quantum plasmons in colloidal semiconductor nanocrystals.

Schimpf AM, Thakkar N, Gunthardt CE, Masiello DJ, Gamelin DR.

ACS Nano. 2014 Jan 28;8(1):1065-72. doi: 10.1021/nn406126u. Epub 2013 Dec 30.

PMID:
24359559
40.

Edoxaban versus warfarin in patients with atrial fibrillation.

Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM; ENGAGE AF-TIMI 48 Investigators.

N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19.

PMID:
24251359
41.

Role of hypoxia inducible factor-1α in the regulation of the cancer-specific variant of organic anion transporting polypeptide 1B3 (OATP1B3), in colon and pancreatic cancer.

Han S, Kim K, Thakkar N, Kim D, Lee W.

Biochem Pharmacol. 2013 Sep 15;86(6):816-23. doi: 10.1016/j.bcp.2013.07.020. Epub 2013 Aug 4.

PMID:
23924606
42.

Herpes zoster meningitis with multidermatomal rash in an immunocompetent patient.

Goyal H, Thakkar N, Bagheri F, Srivastava S.

Am J Emerg Med. 2013 Nov;31(11):1622.e1-2. doi: 10.1016/j.ajem.2013.06.021. Epub 2013 Jul 26.

PMID:
23891595
43.

A cancer-specific variant of the SLCO1B3 gene encodes a novel human organic anion transporting polypeptide 1B3 (OATP1B3) localized mainly in the cytoplasm of colon and pancreatic cancer cells.

Thakkar N, Kim K, Jang ER, Han S, Kim K, Kim D, Merchant N, Lockhart AC, Lee W.

Mol Pharm. 2013 Jan 7;10(1):406-16. doi: 10.1021/mp3005353. Epub 2012 Dec 24.

PMID:
23215050
44.

Development and characterization of solid lipid nanoparticles for enhancement of oral bioavailability of Raloxifene.

Patel BD, Modi RV, Thakkar NA, Patel AA, Thakkar PH.

J Pharm Bioallied Sci. 2012 Mar;4(Suppl 1):S14-6. doi: 10.4103/0975-7406.94121.

45.

The Sequential Organ Failure Assessment score and copeptin for predicting survival in ventilator-associated pneumonia.

Boeck L, Eggimann P, Smyrnios N, Pargger H, Thakkar N, Siegemund M, Morgenthaler NG, Rakic J, Tamm M, Stolz D.

J Crit Care. 2012 Oct;27(5):523.e1-9. doi: 10.1016/j.jcrc.2011.07.081. Epub 2011 Sep 29.

PMID:
21958973
46.

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.

Blasius M, Forment JV, Thakkar N, Wagner SA, Choudhary C, Jackson SP.

Genome Biol. 2011 Aug 18;12(8):R78. doi: 10.1186/gb-2011-12-8-r78.

47.

Pancreatic stone protein: a marker of organ failure and outcome in ventilator-associated pneumonia.

Boeck L, Graf R, Eggimann P, Pargger H, Raptis DA, Smyrnios N, Thakkar N, Siegemund M, Rakic J, Tamm M, Stolz D.

Chest. 2011 Oct;140(4):925-932. doi: 10.1378/chest.11-0018. Epub 2011 Aug 11.

PMID:
21835904
48.

Combinatorial approaches to the prevention and treatment of HIV-1 infection.

Pirrone V, Thakkar N, Jacobson JM, Wigdahl B, Krebs FC.

Antimicrob Agents Chemother. 2011 May;55(5):1831-42. doi: 10.1128/AAC.00976-10. Epub 2011 Feb 22. Review.

49.

Midregional pro-atrial natriuretic peptide and procalcitonin improve survival prediction in VAP.

Boeck L, Eggimann P, Smyrnios N, Pargger H, Thakkar N, Siegemund M, Marsch S, Rakic J, Tamm M, Stolz D.

Eur Respir J. 2011 Mar;37(3):595-603. doi: 10.1183/09031936.00023810. Epub 2010 Jun 7.

50.

Complications of titanium and stainless steel elastic nail fixation of pediatric femoral fractures.

Thakkar NN.

J Bone Joint Surg Am. 2010 May;92(5):1318; author reply 1318. No abstract available.

PMID:
20439694

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