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Items: 1 to 50 of 56

1.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I.

Cell. 2019 Jul 25;178(3):686-698.e14. doi: 10.1016/j.cell.2019.05.054. Epub 2019 Jun 27.

PMID:
31257031
2.

IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response.

Bernshtein B, Curato C, Ioannou M, Thaiss CA, Gross-Vered M, Kolesnikov M, Wang Q, David E, Chappell-Maor L, Harmelin A, Elinav E, Thakker P, Papayannopoulos V, Jung S.

Sci Immunol. 2019 Jun 14;4(36). pii: eaau6571. doi: 10.1126/sciimmunol.aau6571.

PMID:
31201258
3.

The path toward using microbial metabolites as therapies.

Descamps HC, Herrmann B, Wiredu D, Thaiss CA.

EBioMedicine. 2019 Jun;44:747-754. doi: 10.1016/j.ebiom.2019.05.063. Epub 2019 Jun 11. Review.

4.

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs.

Virtue AT, McCright SJ, Wright JM, Jimenez MT, Mowel WK, Kotzin JJ, Joannas L, Basavappa MG, Spencer SP, Clark ML, Eisennagel SH, Williams A, Levy M, Manne S, Henrickson SE, Wherry EJ, Thaiss CA, Elinav E, Henao-Mejia J.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaav1892. doi: 10.1126/scitranslmed.aav1892.

PMID:
31189717
5.

Digitalizing the Microbiome for Human Health.

Nath K, Thaiss CA.

mSystems. 2019 Jun 4;4(3). pii: e00129-19. doi: 10.1128/mSystems.00129-19.

6.

The Dimension of Time in Host-Microbiome Interactions.

Uhr GT, Dohnalová L, Thaiss CA.

mSystems. 2019 Feb 19;4(1). pii: e00216-18. doi: 10.1128/mSystems.00216-18. eCollection 2019 Jan-Feb.

7.

Microbiome dynamics in obesity.

Thaiss CA.

Science. 2018 Nov 23;362(6417):903-904. doi: 10.1126/science.aav6870. No abstract available.

PMID:
30467161
8.

Intestinal Tolerance, with a Little Help from Our Microbial Friends.

Descamps H, Thaiss CA.

Immunity. 2018 Jul 17;49(1):4-6. doi: 10.1016/j.immuni.2018.06.015.

9.

Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis.

Johnston DGW, Williams MA, Thaiss CA, Cabrera-Rubio R, Raverdeau M, McEntee C, Cotter PD, Elinav E, O'Neill LAJ, Corr SC.

J Crohns Colitis. 2018 Jun 28;12(7):835-848. doi: 10.1093/ecco-jcc/jjy038.

PMID:
29608690
10.

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.

Thaiss CA, Levy M, Grosheva I, Zheng D, Soffer E, Blacher E, Braverman S, Tengeler AC, Barak O, Elazar M, Ben-Zeev R, Lehavi-Regev D, Katz MN, Pevsner-Fischer M, Gertler A, Halpern Z, Harmelin A, Aamar S, Serradas P, Grosfeld A, Shapiro H, Geiger B, Elinav E.

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8.

PMID:
29519916
11.

NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock.

Thaiss CA, Nobs SP, Elinav E.

Cell Metab. 2017 Nov 7;26(5):699-700. doi: 10.1016/j.cmet.2017.10.014.

12.

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation.

Atarashi K, Suda W, Luo C, Kawaguchi T, Motoo I, Narushima S, Kiguchi Y, Yasuma K, Watanabe E, Tanoue T, Thaiss CA, Sato M, Toyooka K, Said HS, Yamagami H, Rice SA, Gevers D, Johnson RC, Segre JA, Chen K, Kolls JK, Elinav E, Morita H, Xavier RJ, Hattori M, Honda K.

Science. 2017 Oct 20;358(6361):359-365. doi: 10.1126/science.aan4526.

13.

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R.

Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.

14.

Circadian Coordination of Antimicrobial Responses.

Tognini P, Thaiss CA, Elinav E, Sassone-Corsi P.

Cell Host Microbe. 2017 Aug 9;22(2):185-192. doi: 10.1016/j.chom.2017.07.007. Review.

15.

The remedy within: will the microbiome fulfill its therapeutic promise?

Thaiss CA, Elinav E.

J Mol Med (Berl). 2017 Oct;95(10):1021-1027. doi: 10.1007/s00109-017-1563-z. Epub 2017 Jun 27. Review.

PMID:
28656322
16.

Post-dieting weight gain: the role of persistent microbiome changes.

Thaiss CA, Shapiro H, Elinav E.

Future Microbiol. 2017 Jun;12:555-559. doi: 10.2217/fmb-2017-0045. Epub 2017 Jun 12. No abstract available.

PMID:
28604101
17.

CCR2 Regulates the Immune Response by Modulating the Interconversion and Function of Effector and Regulatory T Cells.

Bakos E, Thaiss CA, Kramer MP, Cohen S, Radomir L, Orr I, Kaushansky N, Ben-Nun A, Becker-Herman S, Shachar I.

J Immunol. 2017 Jun 15;198(12):4659-4671. doi: 10.4049/jimmunol.1601458. Epub 2017 May 15.

18.

Dysbiosis and the immune system.

Levy M, Kolodziejczyk AA, Thaiss CA, Elinav E.

Nat Rev Immunol. 2017 Apr;17(4):219-232. doi: 10.1038/nri.2017.7. Epub 2017 Mar 6. Review.

PMID:
28260787
19.

NLRP6: A Multifaceted Innate Immune Sensor.

Levy M, Shapiro H, Thaiss CA, Elinav E.

Trends Immunol. 2017 Apr;38(4):248-260. doi: 10.1016/j.it.2017.01.001. Epub 2017 Feb 15. Review.

PMID:
28214100
20.

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.

Thaiss CA, Levy M, Korem T, Dohnalová L, Shapiro H, Jaitin DA, David E, Winter DR, Gury-BenAri M, Tatirovsky E, Tuganbaev T, Federici S, Zmora N, Zeevi D, Dori-Bachash M, Pevsner-Fischer M, Kartvelishvily E, Brandis A, Harmelin A, Shibolet O, Halpern Z, Honda K, Amit I, Segal E, Elinav E.

Cell. 2016 Dec 1;167(6):1495-1510.e12. doi: 10.1016/j.cell.2016.11.003.

21.

Persistent microbiome alterations modulate the rate of post-dieting weight regain.

Thaiss CA, Itav S, Rothschild D, Meijer MT, Levy M, Moresi C, Dohnalová L, Braverman S, Rozin S, Malitsky S, Dori-Bachash M, Kuperman Y, Biton I, Gertler A, Harmelin A, Shapiro H, Halpern Z, Aharoni A, Segal E, Elinav E.

Nature. 2016 Dec 22;540(7634):544-551. doi: 10.1038/nature20796. Epub 2016 Nov 24.

PMID:
27906159
22.

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

Gury-BenAri M, Thaiss CA, Serafini N, Winter DR, Giladi A, Lara-Astiaso D, Levy M, Salame TM, Weiner A, David E, Shapiro H, Dori-Bachash M, Pevsner-Fischer M, Lorenzo-Vivas E, Keren-Shaul H, Paul F, Harmelin A, Eberl G, Itzkovitz S, Tanay A, Di Santo JP, Elinav E, Amit I.

Cell. 2016 Aug 25;166(5):1231-1246.e13. doi: 10.1016/j.cell.2016.07.043. Epub 2016 Aug 18.

23.

Metabolites: messengers between the microbiota and the immune system.

Levy M, Thaiss CA, Elinav E.

Genes Dev. 2016 Jul 15;30(14):1589-97. doi: 10.1101/gad.284091.116. Review.

24.

The microbiome and innate immunity.

Thaiss CA, Zmora N, Levy M, Elinav E.

Nature. 2016 Jul 7;535(7610):65-74. doi: 10.1038/nature18847. Review.

PMID:
27383981
25.

Microglia development follows a stepwise program to regulate brain homeostasis.

Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I.

Science. 2016 Aug 19;353(6301):aad8670. doi: 10.1126/science.aad8670. Epub 2016 Jun 23.

26.

It's in the Milk: Feeding the Microbiome to Promote Infant Growth.

Bashiardes S, Thaiss CA, Elinav E.

Cell Metab. 2016 Mar 8;23(3):393-4. doi: 10.1016/j.cmet.2016.02.015.

27.

Integration of Innate Immune Signaling.

Thaiss CA, Levy M, Itav S, Elinav E.

Trends Immunol. 2016 Feb;37(2):84-101. doi: 10.1016/j.it.2015.12.003. Epub 2016 Jan 2. Review.

PMID:
26755064
28.

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, Latz E, Flavell RA, Amit I, Segal E, Elinav E.

Cell. 2015 Dec 3;163(6):1428-43. doi: 10.1016/j.cell.2015.10.048.

29.

Corrigendum: NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.

Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA.

Nature. 2016 Feb 25;530(7591):504. doi: 10.1038/nature16074. Epub 2015 Nov 25. No abstract available.

PMID:
26605525
30.

Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome.

Levy M, Thaiss CA, Elinav E.

Genome Med. 2015 Nov 20;7:120. doi: 10.1186/s13073-015-0249-9. Review.

31.

Q&A: Chance encounters.

Beutler B, Thaiss CA.

Nature. 2015 Oct 22;526(7574):S59-60. doi: 10.1038/526S59a. No abstract available.

PMID:
26488245
32.

Chronobiomics: The Biological Clock as a New Principle in Host-Microbial Interactions.

Thaiss CA, Levy M, Elinav E.

PLoS Pathog. 2015 Oct 8;11(10):e1005113. doi: 10.1371/journal.ppat.1005113. eCollection 2015 Oct. Review. No abstract available.

33.

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.

Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, Elinav E, Segal E.

Science. 2015 Sep 4;349(6252):1101-1106. doi: 10.1126/science.aac4812. Epub 2015 Jul 30.

34.

NF-κB Regulation by NLRs: T Cells Join the Club.

Thaiss CA, Elinav E.

Immunity. 2015 Apr 21;42(4):595-7. doi: 10.1016/j.immuni.2015.03.010.

35.

A day in the life of the meta-organism: diurnal rhythms of the intestinal microbiome and its host.

Thaiss CA, Zeevi D, Levy M, Segal E, Elinav E.

Gut Microbes. 2015;6(2):137-42. doi: 10.1080/19490976.2015.1016690. Review.

36.

Taming the inflammasome.

Levy M, Thaiss CA, Elinav E.

Nat Med. 2015 Mar;21(3):213-5. doi: 10.1038/nm.3808. No abstract available.

PMID:
25742454
37.

Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis.

Thaiss CA, Zeevi D, Levy M, Zilberman-Schapira G, Suez J, Tengeler AC, Abramson L, Katz MN, Korem T, Zmora N, Kuperman Y, Biton I, Gilad S, Harmelin A, Shapiro H, Halpern Z, Segal E, Elinav E.

Cell. 2014 Oct 23;159(3):514-29. doi: 10.1016/j.cell.2014.09.048. Epub 2014 Oct 16.

38.

Inflammasomes and the microbiota--partners in the preservation of mucosal homeostasis.

Levy M, Thaiss CA, Katz MN, Suez J, Elinav E.

Semin Immunopathol. 2015 Jan;37(1):39-46. doi: 10.1007/s00281-014-0451-7. Epub 2014 Oct 15. Review.

PMID:
25315349
39.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota.

Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, Segal E, Elinav E.

Nature. 2014 Oct 9;514(7521):181-6. doi: 10.1038/nature13793. Epub 2014 Sep 17.

PMID:
25231862
40.

A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation.

Hecht G, Bar-Nathan C, Milite G, Alon I, Moshe Y, Greenfeld L, Dotsenko N, Suez J, Levy M, Thaiss CA, Dafni H, Elinav E, Harmelin A.

Lab Anim. 2014 Oct;48(4):292-7. doi: 10.1177/0023677214544728. Epub 2014 Aug 5.

PMID:
25097255
41.

The cross talk between microbiota and the immune system: metabolites take center stage.

Shapiro H, Thaiss CA, Levy M, Elinav E.

Curr Opin Immunol. 2014 Oct;30:54-62. doi: 10.1016/j.coi.2014.07.003. Epub 2014 Jul 26. Review.

PMID:
25064714
42.

Exploring new horizons in microbiome research.

Thaiss CA, Elinav E.

Cell Host Microbe. 2014 Jun 11;15(6):662-7. doi: 10.1016/j.chom.2014.05.016.

43.

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion.

Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA.

Cell. 2014 Feb 27;156(5):1045-59. doi: 10.1016/j.cell.2014.01.026.

44.

The interplay between the innate immune system and the microbiota.

Thaiss CA, Levy M, Suez J, Elinav E.

Curr Opin Immunol. 2014 Feb;26:41-8. doi: 10.1016/j.coi.2013.10.016. Epub 2013 Nov 22. Review.

PMID:
24556399
45.

Inflammasomes and metabolic disease.

Henao-Mejia J, Elinav E, Thaiss CA, Flavell RA.

Annu Rev Physiol. 2014;76:57-78. doi: 10.1146/annurev-physiol-021113-170324. Epub 2013 Nov 21. Review.

PMID:
24274736
46.

Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms.

Elinav E, Nowarski R, Thaiss CA, Hu B, Jin C, Flavell RA.

Nat Rev Cancer. 2013 Nov;13(11):759-71. doi: 10.1038/nrc3611. Review.

PMID:
24154716
47.

Role of the intestinal microbiome in liver disease.

Henao-Mejia J, Elinav E, Thaiss CA, Licona-Limon P, Flavell RA.

J Autoimmun. 2013 Oct;46:66-73. doi: 10.1016/j.jaut.2013.07.001. Epub 2013 Sep 24. Review.

PMID:
24075647
48.

Analysis of microbiota alterations in inflammasome-deficient mice.

Elinav E, Thaiss CA, Flavell RA.

Methods Mol Biol. 2013;1040:185-94. doi: 10.1007/978-1-62703-523-1_14.

PMID:
23852605
49.

The intestinal microbiota in chronic liver disease.

Henao-Mejia J, Elinav E, Thaiss CA, Flavell RA.

Adv Immunol. 2013;117:73-97. doi: 10.1016/B978-0-12-410524-9.00003-7. Review.

PMID:
23611286
50.

NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.

Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA.

Nature. 2012 Apr 25;484(7395):510-3. doi: 10.1038/nature11012. Erratum in: Nature. 2016 Feb 25;530(7591):504.

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