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The TiME Trial: A Fully Embedded, Cluster-Randomized, Pragmatic Trial of Hemodialysis Session Duration.

Dember LM, Lacson E Jr, Brunelli SM, Hsu JY, Cheung AK, Daugirdas JT, Greene T, Kovesdy CP, Miskulin DC, Thadhani RI, Winkelmayer WC, Ellenberg SS, Cifelli D, Madigan R, Young A, Angeletti M, Wingard RL, Kahn C, Nissenson AR, Maddux FW, Abbott KC, Landis JR.

J Am Soc Nephrol. 2019 May;30(5):890-903. doi: 10.1681/ASN.2018090945. Epub 2019 Apr 18.


Blood Microbiome Profile in CKD : A Pilot Study.

Shah NB, Allegretti AS, Nigwekar SU, Kalim S, Zhao S, Lelouvier B, Servant F, Serena G, Thadhani RI, Raj DS, Fasano A.

Clin J Am Soc Nephrol. 2019 May 7;14(5):692-701. doi: 10.2215/CJN.12161018. Epub 2019 Apr 8.


Metabolomics biomarkers and the risk of overall mortality and ESRD in CKD: Results from the Progredir Cohort.

Titan SM, Venturini G, Padilha K, Goulart AC, Lotufo PA, Bensenor IJ, Krieger JE, Thadhani RI, Rhee EP, Pereira AC.

PLoS One. 2019 Mar 18;14(3):e0213764. doi: 10.1371/journal.pone.0213764. eCollection 2019.


Aiming Too Low: Reevaluation of Target Concentrations of Serum 25-Hydroxyvitamin D in Secondary Hyperparathyroidism.

Berg AH, Thadhani RI.

Am J Nephrol. 2019;49(4):281-283. doi: 10.1159/000499160. Epub 2019 Mar 15. No abstract available.


1,5-Anhydroglucitol predicts CKD progression in macroalbuminuric diabetic kidney disease: results from non-targeted metabolomics.

Tavares G, Venturini G, Padilha K, Zatz R, Pereira AC, Thadhani RI, Rhee EP, Titan SMO.

Metabolomics. 2018 Feb 27;14(4):39. doi: 10.1007/s11306-018-1337-9.


Cardiovascular Outcomes in African Americans with Sickle Cell Trait and Chronic Kidney Disease.

Olaniran KO, Eneanya ND, Allegretti AS, Zhao SH, Achebe MM, Thadhani RI.

Am J Nephrol. 2019;49(2):93-102. doi: 10.1159/000496058. Epub 2019 Jan 9.


Predicting the Future Is Not Difficult.

Cerdeira AS, Thadhani RI.

Hypertension. 2019 Jan;73(1):47-48. doi: 10.1161/HYPERTENSIONAHA.118.11931. No abstract available.


Sickle Cell Nephropathy in the Pediatric Population.

Olaniran KO, Eneanya ND, Nigwekar SU, Vela-Parada XF, Achebe MM, Sharma A, Thadhani RI.

Blood Purif. 2019;47(1-3):205-213. doi: 10.1159/000494581. Epub 2018 Dec 5. Review.


Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease.

Sircar M, Rosales IA, Selig MK, Xu D, Zsengeller ZK, Stillman IE, Libermann TA, Karumanchi SA, Thadhani RI.

Am J Pathol. 2018 Oct;188(10):2147-2154. doi: 10.1016/j.ajpath.2018.06.018.


Angiogenic biomarkers in triage and risk for preeclampsia with severe features.

Rana S, Salahuddin S, Mueller A, Berg AH, Thadhani RI, Karumanchi SA.

Pregnancy Hypertens. 2018 Jul;13:100-106. doi: 10.1016/j.preghy.2018.05.008. Epub 2018 May 25.


Metabolites related to eGFR: Evaluation of candidate molecules for GFR estimation using untargeted metabolomics.

Titan SM, Venturini G, Padilha K, Tavares G, Zatz R, Bensenor I, Lotufo PA, Rhee EP, Thadhani RI, Pereira AC.

Clin Chim Acta. 2019 Feb;489:242-248. doi: 10.1016/j.cca.2018.08.037. Epub 2018 Aug 25.


Serum Angiopoietin-2 Predicts Mortality and Kidney Outcomes in Decompensated Cirrhosis.

Allegretti AS, Vela Parada X, Ortiz GA, Long J, Krinsky S, Zhao S, Fuchs BC, Sojoodi M, Zhang D, Karumanchi SA, Kalim S, Nigwekar SU, Thadhani RI, Parikh SM, Chung RT.

Hepatology. 2019 Feb;69(2):729-741. doi: 10.1002/hep.30230. Epub 2019 Jan 4.


De novo NAD+ biosynthetic impairment in acute kidney injury in humans.

Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM.

Nat Med. 2018 Sep;24(9):1351-1359. doi: 10.1038/s41591-018-0138-z. Epub 2018 Aug 20.


Calciphylaxis in Patients With Normal Renal Function: A Case Series and Systematic Review.

Bajaj R, Courbebaisse M, Kroshinsky D, Thadhani RI, Nigwekar SU.

Mayo Clin Proc. 2018 Sep;93(9):1202-1212. doi: 10.1016/j.mayocp.2018.06.001. Epub 2018 Jul 27.


Association of Smoking Status With Mortality and Hospitalization in Hemodialysis Patients.

Li NC, Thadhani RI, Reviriego-Mendoza M, Larkin JW, Maddux FW, Ofsthun NJ.

Am J Kidney Dis. 2018 Nov;72(5):673-681. doi: 10.1053/j.ajkd.2018.04.004. Epub 2018 Jun 15.


The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study.

Srivastava A, Palsson R, Kaze AD, Chen ME, Palacios P, Sabbisetti V, Betensky RA, Steinman TI, Thadhani RI, McMahon GM, Stillman IE, Rennke HG, Waikar SS.

J Am Soc Nephrol. 2018 Aug;29(8):2213-2224. doi: 10.1681/ASN.2017121260. Epub 2018 Jun 4.


Epidemiology: Chronic disease, cancer, and exercise - a common link.

Allegretti AS, Thadhani RI.

Nat Rev Nephrol. 2018 May;14(5):288-290. doi: 10.1038/nrneph.2018.24. Epub 2018 Mar 26. No abstract available.


Acute Homeostatic Changes Following Vitamin D2 Supplementation.

Berg AH, Bhan I, Powe C, Karumanchi SA, Xu D, Thadhani RI.

J Endocr Soc. 2017 Jul 19;1(9):1135-1149. doi: 10.1210/js.2017-00244. eCollection 2017 Sep 1.


Increased Bone Morphogenetic Protein Signaling in the Cutaneous Vasculature of Patients with Calciphylaxis.

Nigwekar SU, Jiramongkolchai P, Wunderer F, Bloch E, Ichinose R, Nazarian RM, Thadhani RI, Malhotra R, Bloch DB.

Am J Nephrol. 2017;46(5):429-438. doi: 10.1159/000484418. Epub 2017 Nov 9.


Prognosis of Patients with Cirrhosis and AKI Who Initiate RRT.

Allegretti AS, Parada XV, Eneanya ND, Gilligan H, Xu D, Zhao S, Dienstag JL, Chung RT, Thadhani RI.

Clin J Am Soc Nephrol. 2018 Jan 6;13(1):16-25. doi: 10.2215/CJN.03610417. Epub 2017 Nov 9.


The dynamics of the metabolism of acetate and bicarbonate associated with use of hemodialysates in the ABChD trial: a phase IV, prospective, single center, single blind, randomized, cross-over, two week investigation.

Smith WB, Gibson S, Newman GE, Hendon KS, Askelson M, Zhao J, Hantash J, Flanagan B, Larkin JW, Usvyat LA, Thadhani RI, Maddux FW.

BMC Nephrol. 2017 Aug 29;18(1):273. doi: 10.1186/s12882-017-0683-6.


Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia.

Khedkar SA, Samad MA, Choudhury S, Lee JY, Zhang D, Thadhani RI, Karumanchi SA, Rigby AC, Kang PM.

Sci Rep. 2017 Aug 16;7(1):8427. doi: 10.1038/s41598-017-08670-y.


Characterization and Correction of Olfactory Deficits in Kidney Disease.

Nigwekar SU, Weiser JM, Kalim S, Xu D, Wibecan JL, Dougherty SM, Mercier-Lafond L, Corapi KM, Eneanya ND, Holbrook EH, Brown D, Thadhani RI, Păunescu TG.

J Am Soc Nephrol. 2017 Nov;28(11):3395-3403. doi: 10.1681/ASN.2016121308. Epub 2017 Aug 3.


Low Sodium Diet, Vitamin D, or Both for RAASi-Resistant, Residual, Proteinuria in CKD? The ViRTUE Trial Points the Way Forward but Is Not the Last Word.

Goldsmith D, Thadhani RI.

J Am Soc Nephrol. 2017 Apr;28(4):1016-1019. doi: 10.1681/ASN.2016121321. Epub 2017 Feb 28. No abstract available.


Angiogenic Markers in Transition: Thinking Positive.

Hagmann H, Thadhani RI.

Hypertension. 2017 Apr;69(4):578-579. doi: 10.1161/HYPERTENSIONAHA.116.08739. Epub 2017 Feb 6. No abstract available.


Macrophage migration inhibitory factor as a novel biomarker of portopulmonary hypertension.

DuBrock HM, Rodriguez-Lopez JM, LeVarge BL, Curry MP, VanderLaan PA, Zsengeller ZK, Pernicone E, Preston IR, Yu PB, Nikolic I, Xu D, Thadhani RI, Channick RN, Ananth Karumanchi S.

Pulm Circ. 2016 Dec;6(4):498-507. doi: 10.1086/688489.


Vitamin K-Dependent Carboxylation of Matrix Gla Protein Influences the Risk of Calciphylaxis.

Nigwekar SU, Bloch DB, Nazarian RM, Vermeer C, Booth SL, Xu D, Thadhani RI, Malhotra R.

J Am Soc Nephrol. 2017 Jun;28(6):1717-1722. doi: 10.1681/ASN.2016060651. Epub 2017 Jan 3.


Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.

Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT.

Kidney Int Rep. 2016 Sep;1(3):135-143.


A Nationally Representative Study of Calcific Uremic Arteriolopathy Risk Factors.

Nigwekar SU, Zhao S, Wenger J, Hymes JL, Maddux FW, Thadhani RI, Chan KE.

J Am Soc Nephrol. 2016 Nov;27(11):3421-3429. Epub 2016 Apr 14.


Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice.

Cavalli RC, Cerdeira AS, Pernicone E, Korkes HA, Burke SD, Rajakumar A, Thadhani RI, Roberts DJ, Bhasin M, Karumanchi SA, Kopcow HD.

PLoS One. 2016 Oct 13;11(10):e0164353. doi: 10.1371/journal.pone.0164353. eCollection 2016.


Siglec-7 as a Novel Biomarker to Predict Mortality in Decompensated Cirrhosis and Acute Kidney Injury.

Allegretti AS, Ortiz G, Kalim S, Wibecan J, Zhang D, Shan HY, Xu D, Chung RT, Karumanchi SA, Thadhani RI.

Dig Dis Sci. 2016 Dec;61(12):3609-3620. Epub 2016 Sep 21.


Reduction of carbamylated albumin by extended hemodialysis.

Perl J, Kalim S, Wald R, Goldstein MB, Yan AT, Noori N, Kiaii M, Wenger J, Chan C, Thadhani RI, Karumanchi SA, Berg AH.

Hemodial Int. 2016 Oct;20(4):510-521. doi: 10.1111/hdi.12435. Epub 2016 Jun 21.


Mild prolonged chronic hyponatremia and risk of hip fracture in the elderly.

Ayus JC, Fuentes NA, Negri AL, Moritz ML, Giunta DH, Kalantar-Zadeh K, Nigwekar SU, Thadhani RI, Go AS, De Quiros FG.

Nephrol Dial Transplant. 2016 Oct;31(10):1662-9. doi: 10.1093/ndt/gfw029. Epub 2016 Mar 23.


Changes in Kidney Function After Transjugular Intrahepatic Portosystemic Shunts Versus Large-Volume Paracentesis in Cirrhosis: A Matched Cohort Analysis.

Allegretti AS, Ortiz G, Cui J, Wenger J, Bhan I, Chung RT, Thadhani RI, Irani Z.

Am J Kidney Dis. 2016 Sep;68(3):381-91. doi: 10.1053/j.ajkd.2016.02.041. Epub 2016 Mar 16.


The greatly misunderstood erythropoietin resistance index and the case for a new responsiveness measure.

Chait Y, Kalim S, Horowitz J, Hollot CV, Ankers ED, Germain MJ, Thadhani RI.

Hemodial Int. 2016 Jul;20(3):392-8. doi: 10.1111/hdi.12407. Epub 2016 Feb 3.


Type 1, type 2 and gestational diabetes mellitus differentially impact placental pathologic characteristics of uteroplacental malperfusion.

Huynh J, Yamada J, Beauharnais C, Wenger JB, Thadhani RI, Wexler D, Roberts DJ, Bentley-Lewis R.

Placenta. 2015 Oct;36(10):1161-6. doi: 10.1016/j.placenta.2015.08.004. Epub 2015 Aug 12.


Prognosis of Acute Kidney Injury and Hepatorenal Syndrome in Patients with Cirrhosis: A Prospective Cohort Study.

Allegretti AS, Ortiz G, Wenger J, Deferio JJ, Wibecan J, Kalim S, Tamez H, Chung RT, Karumanchi SA, Thadhani RI.

Int J Nephrol. 2015;2015:108139. doi: 10.1155/2015/108139. Epub 2015 Jul 22.


Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.

Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY.

BMC Nephrol. 2015 Jul 31;16:119. doi: 10.1186/s12882-015-0120-7.


Calciphylaxis: risk factors, diagnosis, and treatment.

Nigwekar SU, Kroshinsky D, Nazarian RM, Goverman J, Malhotra R, Jackson VA, Kamdar MM, Steele DJ, Thadhani RI.

Am J Kidney Dis. 2015 Jul;66(1):133-46. doi: 10.1053/j.ajkd.2015.01.034. Epub 2015 May 7. Review.


24,25-Dihydroxyvitamin d3 and vitamin D status of community-dwelling black and white Americans.

Berg AH, Powe CE, Evans MK, Wenger J, Ortiz G, Zonderman AB, Suntharalingam P, Lucchesi K, Powe NR, Karumanchi SA, Thadhani RI.

Clin Chem. 2015 Jun;61(6):877-84. doi: 10.1373/clinchem.2015.240051. Epub 2015 Apr 28.


The Effects of Parenteral Amino Acid Therapy on Protein Carbamylation in Maintenance Hemodialysis Patients.

Kalim S, Ortiz G, Trottier CA, Deferio JJ, Karumanchi SA, Thadhani RI, Berg AH.

J Ren Nutr. 2015 Jul;25(4):388-92. doi: 10.1053/j.jrn.2015.01.019. Epub 2015 Mar 5.


Protein carbamylation is associated with heart failure and mortality in diabetic patients with end-stage renal disease.

Drechsler C, Kalim S, Wenger JB, Suntharalingam P, Hod T, Thadhani RI, Karumanchi SA, Wanner C, Berg AH.

Kidney Int. 2015 Jun;87(6):1201-8. doi: 10.1038/ki.2014.429. Epub 2015 Feb 11.


Revisiting KDIGO clinical practice guideline on chronic kidney disease-mineral and bone disorder: a commentary from a Kidney Disease: Improving Global Outcomes controversies conference.

Ketteler M, Elder GJ, Evenepoel P, Ix JH, Jamal SA, Lafage-Proust MH, Shroff R, Thadhani RI, Tonelli MA, Kasiske BL, Wheeler DC, Leonard MB.

Kidney Int. 2015 Mar;87(3):502-28. doi: 10.1038/ki.2014.425. Epub 2015 Feb 4.


Dabigatran and rivaroxaban use in atrial fibrillation patients on hemodialysis.

Chan KE, Edelman ER, Wenger JB, Thadhani RI, Maddux FW.

Circulation. 2015 Mar 17;131(11):972-9. doi: 10.1161/CIRCULATIONAHA.114.014113. Epub 2015 Jan 16.


In vivo nanoparticle assessment of pathological endothelium predicts the development of inflow stenosis in murine arteriovenous fistula.

Cui J, Kessinger CW, McCarthy JR, Sosnovik DE, Libby P, Thadhani RI, Jaffer FA.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):189-96. doi: 10.1161/ATVBAHA.114.304483. Epub 2014 Nov 13.


Protein carbamylation in kidney disease: pathogenesis and clinical implications.

Kalim S, Karumanchi SA, Thadhani RI, Berg AH.

Am J Kidney Dis. 2014 Nov;64(5):793-803. doi: 10.1053/j.ajkd.2014.04.034. Epub 2014 Jul 16. Review.


Quantifying a rare disease in administrative data: the example of calciphylaxis.

Nigwekar SU, Solid CA, Ankers E, Malhotra R, Eggert W, Turchin A, Thadhani RI, Herzog CA.

J Gen Intern Med. 2014 Aug;29 Suppl 3:S724-31. doi: 10.1007/s11606-014-2910-1.


Adherence barriers to chronic dialysis in the United States.

Chan KE, Thadhani RI, Maddux FW.

J Am Soc Nephrol. 2014 Nov;25(11):2642-8. doi: 10.1681/ASN.2013111160. Epub 2014 Apr 24.


Placental histomorphometry in gestational diabetes mellitus: the relationship between subsequent type 2 diabetes mellitus and race/ethnicity.

Bentley-Lewis R, Dawson DL, Wenger JB, Thadhani RI, Roberts DJ.

Am J Clin Pathol. 2014 Apr;141(4):587-92. doi: 10.1309/AJCPX81AUNFPOTLL.


Vitamin D and chronic kidney disease-mineral bone disease (CKD-MBD).

Nigwekar SU, Tamez H, Thadhani RI.

Bonekey Rep. 2014 Feb 5;3:498. doi: 10.1038/bonekey.2013.232. eCollection 2014.

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