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Items: 1 to 20 of 96

1.

Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.

García-Castellanos R, Nielsen NS, Runager K, Thøgersen IB, Lukassen MV, Poulsen ET, Goulas T, Enghild JJ, Gomis-Rüth FX.

Structure. 2017 Nov 7;25(11):1740-1750.e2. doi: 10.1016/j.str.2017.09.001. Epub 2017 Oct 5.

PMID:
28988748
2.

Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement.

Pihl R, Jensen L, Hansen AG, Thøgersen IB, Andres S, Dagnæs-Hansen F, Oexle K, Enghild JJ, Thiel S.

J Immunol. 2017 Aug 9. pii: ji1700518. doi: 10.4049/jimmunol.1700518. [Epub ahead of print]

PMID:
28794230
3.

Mirolysin, a LysargiNase from Tannerella forsythia, proteolytically inactivates the human cathelicidin, LL-37.

Koneru L, Ksiazek M, Waligorska I, Straczek A, Lukasik M, Madej M, Thøgersen IB, Enghild JJ, Potempa J.

Biol Chem. 2016 Dec 20. pii: /j/bchm.ahead-of-print/hsz-2016-0267/hsz-2016-0267.xml. doi: 10.1515/hsz-2016-0267. [Epub ahead of print]

4.

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

Lasica AM, Goulas T, Mizgalska D, Zhou X, de Diego I, Ksiazek M, Madej M, Guo Y, Guevara T, Nowak M, Potempa B, Goel A, Sztukowska M, Prabhakar AT, Bzowska M, Widziolek M, Thøgersen IB, Enghild JJ, Simonian M, Kulczyk AW, Nguyen KA, Potempa J, Gomis-Rüth FX.

Sci Rep. 2016 Nov 24;6:37708. doi: 10.1038/srep37708.

5.

Disulfide Bond Pattern of Transforming Growth Factor β-Induced Protein.

Lukassen MV, Scavenius C, Thøgersen IB, Enghild JJ.

Biochemistry. 2016 Oct 4;55(39):5610-5621. Epub 2016 Sep 23.

PMID:
27609313
6.

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain.

de Diego I, Ksiazek M, Mizgalska D, Koneru L, Golik P, Szmigielski B, Nowak M, Nowakowska Z, Potempa B, Houston JA, Enghild JJ, Thøgersen IB, Gao J, Kwan AH, Trewhella J, Dubin G, Gomis-Rüth FX, Nguyen KA, Potempa J.

Sci Rep. 2016 Mar 23;6:23123. doi: 10.1038/srep23123.

7.

The Compact and Biologically Relevant Structure of Inter-α-inhibitor Is Maintained by the Chondroitin Sulfate Chain and Divalent Cations.

Scavenius C, Nikolajsen CL, Stenvang M, Thøgersen IB, Wyrożemski Ł, Wisniewski HG, Otzen DE, Sanggaard KW, Enghild JJ.

J Biol Chem. 2016 Feb 26;291(9):4658-70. doi: 10.1074/jbc.M115.678748. Epub 2016 Jan 4.

8.

Enzymatic and Structural Characterization of the Major Endopeptidase in the Venus Flytrap Digestion Fluid.

Risør MW, Thomsen LR, Sanggaard KW, Nielsen TA, Thøgersen IB, Lukassen MV, Rossen L, Garcia-Ferrer I, Guevara T, Scavenius C, Meinjohanns E, Gomis-Rüth FX, Enghild JJ.

J Biol Chem. 2016 Jan 29;291(5):2271-87. doi: 10.1074/jbc.M115.672550. Epub 2015 Dec 1.

9.

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase.

Staniec D, Ksiazek M, Thøgersen IB, Enghild JJ, Sroka A, Bryzek D, Bogyo M, Abrahamson M, Potempa J.

J Biol Chem. 2015 Nov 6;290(45):27248-60. doi: 10.1074/jbc.M115.648782. Epub 2015 Sep 18.

10.

Characterization of the gila monster (Heloderma suspectum suspectum) venom proteome.

Sanggaard KW, Dyrlund TF, Thomsen LR, Nielsen TA, Brøndum L, Wang T, Thøgersen IB, Enghild JJ.

Data Brief. 2015 Feb 13;3:137-42. doi: 10.1016/j.dib.2015.01.007. eCollection 2015 Jun.

11.

KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure.

Ksiazek M, Mizgalska D, Eick S, Thøgersen IB, Enghild JJ, Potempa J.

Front Microbiol. 2015 Apr 21;6:312. doi: 10.3389/fmicb.2015.00312. eCollection 2015.

12.

Characterization of the gila monster (Heloderma suspectum suspectum) venom proteome.

Sanggaard KW, Dyrlund TF, Thomsen LR, Nielsen TA, Brøndum L, Wang T, Thøgersen IB, Enghild JJ.

J Proteomics. 2015 Mar 18;117:1-11. doi: 10.1016/j.jprot.2015.01.004. Epub 2015 Jan 17.

PMID:
25603280
13.

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1).

Shitomi Y, Thøgersen IB, Ito N, Leitinger B, Enghild JJ, Itoh Y.

Mol Biol Cell. 2015 Feb 15;26(4):659-73. doi: 10.1091/mbc.E14-10-1463. Epub 2014 Dec 24.

14.

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia.

Ksiazek M, Karim AY, Bryzek D, Enghild JJ, Thøgersen IB, Koziel J, Potempa J.

Biol Chem. 2015 Mar;396(3):261-75. doi: 10.1515/hsz-2014-0256.

15.

Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop.

Ksiazek M, Mizgalska D, Enghild JJ, Scavenius C, Thogersen IB, Potempa J.

J Biol Chem. 2015 Jan 2;290(1):658-70. doi: 10.1074/jbc.M114.601716. Epub 2014 Nov 11.

16.

Proteomics of Fuchs' endothelial corneal dystrophy support that the extracellular matrix of Descemet's membrane is disordered.

Poulsen ET, Dyrlund TF, Runager K, Scavenius C, Krogager TP, Højrup P, Thøgersen IB, Sanggaard KW, Vorum H, Hjortdal J, Enghild JJ.

J Proteome Res. 2014 Nov 7;13(11):4659-67. doi: 10.1021/pr500252r. Epub 2014 Jun 27.

17.

Spider genomes provide insight into composition and evolution of venom and silk.

Sanggaard KW, Bechsgaard JS, Fang X, Duan J, Dyrlund TF, Gupta V, Jiang X, Cheng L, Fan D, Feng Y, Han L, Huang Z, Wu Z, Liao L, Settepani V, Thøgersen IB, Vanthournout B, Wang T, Zhu Y, Funch P, Enghild JJ, Schauser L, Andersen SU, Villesen P, Schierup MH, Bilde T, Wang J.

Nat Commun. 2014 May 6;5:3765. doi: 10.1038/ncomms4765. Erratum in: Nat Commun. 2014;5:4590.

18.

Secreted major Venus flytrap chitinase enables digestion of Arthropod prey.

Paszota P, Escalante-Perez M, Thomsen LR, Risør MW, Dembski A, Sanglas L, Nielsen TA, Karring H, Thøgersen IB, Hedrich R, Enghild JJ, Kreuzer I, Sanggaard KW.

Biochim Biophys Acta. 2014 Feb;1844(2):374-83. doi: 10.1016/j.bbapap.2013.11.009. Epub 2013 Nov 22.

PMID:
24275507
19.

Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits.

Karring H, Poulsen ET, Runager K, Thøgersen IB, Klintworth GK, Højrup P, Enghild JJ.

Mol Vis. 2013 Apr 12;19:861-76. Print 2013.

20.

Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases.

Veillard F, Sztukowska M, Mizgalska D, Ksiazek M, Houston J, Potempa B, Enghild JJ, Thogersen IB, Gomis-Rüth FX, Nguyen KA, Potempa J.

Biochim Biophys Acta. 2013 Aug;1830(8):4218-28. doi: 10.1016/j.bbagen.2013.04.005. Epub 2013 Apr 10.

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