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Best matches for Thérond PP[au]:

The mechanisms of Hedgehog signalling and its roles in development and disease. Briscoe J et al. Nat Rev Mol Cell Biol. (2013)

Endocytosis of Hedgehog through dispatched regulates long-range signaling. D'Angelo G et al. Dev Cell. (2015)

Release and transportation of Hedgehog molecules. Thérond PP et al. Curr Opin Cell Biol. (2012)

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Items: 25


Endocytosis of Hedgehog through dispatched regulates long-range signaling.

D'Angelo G, Matusek T, Pizette S, Thérond PP.

Dev Cell. 2015 Feb 9;32(3):290-303. doi: 10.1016/j.devcel.2014.12.004. Epub 2015 Jan 22.


The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.

Matusek T, Wendler F, Polès S, Pizette S, D'Angelo G, Fürthauer M, Thérond PP.

Nature. 2014 Dec 4;516(7529):99-103. doi: 10.1038/nature13847.


Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.

Ranieri N, Thérond PP, Ruel L.

Nat Commun. 2014 Oct 7;5:5034. doi: 10.1038/ncomms6034.


The mechanisms of Hedgehog signalling and its roles in development and disease.

Briscoe J, Thérond PP.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):416-29. doi: 10.1038/nrm3598. Epub 2013 May 30. Review.


Dally and Notum regulate the switch between low and high level Hedgehog pathway signalling.

Ayers KL, Mteirek R, Cervantes A, Lavenant-Staccini L, Thérond PP, Gallet A.

Development. 2012 Sep;139(17):3168-79. doi: 10.1242/dev.078402.


Release and transportation of Hedgehog molecules.

Thérond PP.

Curr Opin Cell Biol. 2012 Apr;24(2):173-80. doi: 10.1016/ Epub 2012 Feb 24. Review.


Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.

Ranieri N, Ruel L, Gallet A, Raisin S, Thérond PP.

Dev Cell. 2012 Feb 14;22(2):279-94. doi: 10.1016/j.devcel.2011.12.002. Epub 2012 Feb 2.


Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling.

Raisin S, Ruel L, Ranieri N, Staccini-Lavenant L, Thérond PP.

Dev Biol. 2010 Aug 1;344(1):119-28. doi: 10.1016/j.ydbio.2010.04.021. Epub 2010 May 9.


The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum.

Ayers KL, Gallet A, Staccini-Lavenant L, Thérond PP.

Dev Cell. 2010 Apr 20;18(4):605-20. doi: 10.1016/j.devcel.2010.02.015.


Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling.

Ayers KL, Thérond PP.

Trends Cell Biol. 2010 May;20(5):287-98. doi: 10.1016/j.tcb.2010.02.002. Epub 2010 Mar 5. Review.


The full-length unprocessed hedgehog protein is an active signaling molecule.

Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ.

J Biol Chem. 2010 Jan 22;285(4):2562-8. doi: 10.1074/jbc.M109.078626. Epub 2009 Nov 17.


Variations in Hedgehog signaling: divergence and perpetuation in Sufu regulation of Gli.

Ruel L, Thérond PP.

Genes Dev. 2009 Aug 15;23(16):1843-8. doi: 10.1101/gad.1838109.


Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis.

Gallet A, Staccini-Lavenant L, Thérond PP.

Dev Cell. 2008 May;14(5):712-25. doi: 10.1016/j.devcel.2008.03.001.


The role of kinases in the Hedgehog signalling pathway.

Aikin RA, Ayers KL, Thérond PP.

EMBO Rep. 2008 Apr;9(4):330-6. doi: 10.1038/embor.2008.38. Review.


Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.


Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia.

Gallet A, Ruel L, Staccini-Lavenant L, Thérond PP.

Development. 2006 Feb;133(3):407-18. Epub 2006 Jan 5.


Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.

Arquier N, Vigne P, Duplan E, Hsu T, Therond PP, Frelin C, D'Angelo G.

Biochem J. 2006 Jan 15;393(Pt 2):471-80.


Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.

Ruel L, Rodriguez R, Gallet A, Lavenant-Staccini L, Thérond PP.

Nat Cell Biol. 2003 Oct;5(10):907-13. Epub 2003 Oct 1.


Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila.

Gallet A, Angelats C, Kerridge S, Thérond PP.

Development. 2000 Dec;127(24):5509-22.


Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.

Thérond PP, Limbourg Bouchon B, Gallet A, Dussilol F, Pietri T, van den Heuvel M, Tricoire H.

Development. 1999 Sep;126(18):4039-51.


Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

Robbins DJ, Nybakken KE, Kobayashi R, Sisson JC, Bishop JM, Thérond PP.

Cell. 1997 Jul 25;90(2):225-34.


Phosphorylation of the fused protein kinase in response to signaling from hedgehog.

Thérond PP, Knight JD, Kornberg TB, Bishop JM.

Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4224-8.

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