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Items: 1 to 50 of 73

1.

Analysis of intracellular enzyme activity by surface enhanced Raman scattering.

Stevenson R, McAughtrie S, Senior L, Stokes RJ, McGachy H, Tetley L, Nativo P, Brewer JM, Alexander J, Faulds K, Graham D.

Analyst. 2013 Nov 7;138(21):6331-6. doi: 10.1039/c3an00729d.

2.

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei.

Monnerat S, Almeida Costa CI, Forkert AC, Benz C, Hamilton A, Tetley L, Burchmore R, Novo C, Mottram JC, Hammarton TC.

PLoS One. 2013 Jun 21;8(6):e67327. doi: 10.1371/journal.pone.0067327. Print 2013.

3.

A unique Kelch domain phosphatase in Plasmodium regulates ookinete morphology, motility and invasion.

Philip N, Vaikkinen HJ, Tetley L, Waters AP.

PLoS One. 2012;7(9):e44617. doi: 10.1371/journal.pone.0044617. Epub 2012 Sep 5.

4.

Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration.

Lemarié F, Chang CW, Blatchford DR, Amor R, Norris G, Tetley L, McConnell G, Dufès C.

Nanomedicine (Lond). 2013 Feb;8(2):181-92. doi: 10.2217/nnm.12.83. Epub 2012 Aug 14.

5.

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation.

Morrison LS, Goundry A, Faria MS, Tetley L, Eschenlauer SC, Westrop GD, Dostalova A, Volf P, Coombs GH, Lima AP, Mottram JC.

Cell Microbiol. 2012 Aug;14(8):1271-86. doi: 10.1111/j.1462-5822.2012.01798.x. Epub 2012 May 8.

6.

The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement.

May SF, Peacock L, Almeida Costa CI, Gibson WC, Tetley L, Robinson DR, Hammarton TC.

Mol Microbiol. 2012 Apr;84(1):77-92. doi: 10.1111/j.1365-2958.2012.08008.x. Epub 2012 Mar 5.

7.

The use of nano polymeric self-assemblies based on novel amphiphilic polymers for oral hydrophobic drug delivery.

Clare H, Lin PK, Tetley L, Cheng WP.

Pharm Res. 2012 Mar;29(3):782-94. doi: 10.1007/s11095-011-0602-7. Epub 2011 Oct 5.

PMID:
21971828
8.

Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor.

Proto WR, Castanys-Munoz E, Black A, Tetley L, Moss CX, Juliano L, Coombs GH, Mottram JC.

J Biol Chem. 2011 Nov 18;286(46):39914-25. doi: 10.1074/jbc.M111.292334. Epub 2011 Sep 23.

9.

Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex.

Aldawsari H, Edrada-Ebel R, Blatchford DR, Tate RJ, Tetley L, Dufès C.

Biomaterials. 2011 Sep;32(25):5889-99. doi: 10.1016/j.biomaterials.2011.04.079. Epub 2011 May 18.

PMID:
21596431
10.

Novel tocotrienol-entrapping vesicles can eradicate solid tumors after intravenous administration.

Fu JY, Zhang W, Blatchford DR, Tetley L, McConnell G, Dufès C.

J Control Release. 2011 Aug 25;154(1):20-6. doi: 10.1016/j.jconrel.2011.04.015. Epub 2011 Apr 22.

PMID:
21539872
11.

Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex.

Aldawsari H, Raj BS, Edrada-Ebel R, Blatchford DR, Tate RJ, Tetley L, Dufès C.

Nanomedicine. 2011 Oct;7(5):615-23. doi: 10.1016/j.nano.2011.01.016. Epub 2011 Feb 17.

PMID:
21333755
12.

Histological evidence of tissue reaction to gold weights used for mechanical ptosis.

Lockington D, Chadha V, Russell H, Cauchi P, Tetley L, Roberts F, Kemp E.

Arch Ophthalmol. 2010 Oct;128(10):1379-80. doi: 10.1001/archophthalmol.2010.235. No abstract available.

PMID:
20938017
13.

Polyamine aza-cyclic compounds demonstrate anti-proliferative activity in vitro but fail to control tumour growth in vivo.

Wong PE, Tetley L, Dufès C, Chooi KW, Bolton K, Schätzlein AG, Uchegbu IF.

J Pharm Sci. 2010 Nov;99(11):4642-57. doi: 10.1002/jps.22165.

PMID:
20845462
14.

In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes.

Cheng WP, Thompson C, Ryan SM, Aguirre T, Tetley L, Brayden DJ.

J Control Release. 2010 Oct 15;147(2):289-97. doi: 10.1016/j.jconrel.2010.07.128. Epub 2010 Aug 10.

PMID:
20705108
15.

Campylobacter jejuni 81-176 forms distinct microcolonies on in vitro-infected human small intestinal tissue prior to biofilm formation.

Haddock G, Mullin M, MacCallum A, Sherry A, Tetley L, Watson E, Dagleish M, Smith DGE, Everest P.

Microbiology. 2010 Oct;156(Pt 10):3079-3084. doi: 10.1099/mic.0.039867-0. Epub 2010 Jul 8.

PMID:
20616103
16.

Unit-dose dispenser tips: a potential source of ocular injury.

Macdonald EC, Lockington D, Roberts F, Tetley L, Ramaesh K.

Br J Ophthalmol. 2010 Jan;94(1):136-7. doi: 10.1136/bjo.2008.156125. No abstract available.

PMID:
20385533
17.

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA.

Koppu S, Oh YJ, Edrada-Ebel R, Blatchford DR, Tetley L, Tate RJ, Dufès C.

J Control Release. 2010 Apr 19;143(2):215-21. doi: 10.1016/j.jconrel.2009.11.015. Epub 2009 Nov 26.

PMID:
19944722
18.

The molecular shape of poly(propylenimine) dendrimer amphiphiles has a profound effect on their self assembly.

Chooi KW, Gray AI, Tetley L, Fan Y, Uchegbu IF.

Langmuir. 2010 Feb 16;26(4):2301-16. doi: 10.1021/la9027282.

PMID:
19860445
19.

The influence of polymer architecture on the protective effect of novel comb shaped amphiphilic poly(allylamine) against in vitro enzymatic degradation of insulin--towards oral insulin delivery.

Thompson CJ, Tetley L, Cheng WP.

Int J Pharm. 2010 Jan 4;383(1-2):216-27. doi: 10.1016/j.ijpharm.2009.09.018. Epub 2009 Sep 17.

PMID:
19766178
20.

Tumor regression after systemic administration of tocotrienol entrapped in tumor-targeted vesicles.

Fu JY, Blatchford DR, Tetley L, Dufès C.

J Control Release. 2009 Dec 3;140(2):95-9. doi: 10.1016/j.jconrel.2009.08.017. Epub 2009 Aug 23.

PMID:
19709637
21.

Mutation in DSG1 causing autosomal dominant striate palmoplantar keratoderma.

Zamiri M, Smith FJ, Campbell LE, Tetley L, Eady RA, Hodgins MB, McLean WH, Munro CS.

Br J Dermatol. 2009 Sep;161(3):692-4. doi: 10.1111/j.1365-2133.2009.09316.x. Epub 2009 Jun 25. No abstract available.

PMID:
19558595
22.

The complexation between novel comb shaped amphiphilic polyallylamine and insulin: towards oral insulin delivery.

Thompson CJ, Tetley L, Uchegbu IF, Cheng WP.

Int J Pharm. 2009 Jul 6;376(1-2):46-55. doi: 10.1016/j.ijpharm.2009.04.014. Epub 2009 Apr 16.

PMID:
19375489
23.

Rapid cell mapping using nanoparticles and SERRS.

Stokes RJ, McKenzie F, McFarlane E, Ricketts A, Tetley L, Faulds K, Alexander J, Graham D.

Analyst. 2009 Jan;134(1):170-5. doi: 10.1039/b815117b. Epub 2008 Nov 19.

PMID:
19082189
24.

Polymeric amphiphile branching leads to rare nanodisc shaped planar self-assemblies.

Qu X, Omar L, Le TB, Tetley L, Bolton K, Chooi KW, Wang W, Uchegbu IF.

Langmuir. 2008 Sep 16;24(18):9997-10004. doi: 10.1021/la8007848. Epub 2008 Aug 9.

PMID:
18690736
25.

The AP3 adaptor is involved in the transport of membrane proteins to acidocalcisomes of Leishmania.

Besteiro S, Tonn D, Tetley L, Coombs GH, Mottram JC.

J Cell Sci. 2008 Mar 1;121(Pt 5):561-70. doi: 10.1242/jcs.022574. Epub 2008 Feb 5.

26.

McArthur revisited: fluorescence microscopes for field diagnostics.

Jones D, Nyalwidhe J, Tetley L, Barrett MP.

Trends Parasitol. 2007 Oct;23(10):468-9. Epub 2007 Sep 7.

PMID:
17826338
27.

Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis.

Hammarton TC, Kramer S, Tetley L, Boshart M, Mottram JC.

Mol Microbiol. 2007 Sep;65(5):1229-48. Epub 2007 Jul 27.

29.

Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana.

Williams RA, Tetley L, Mottram JC, Coombs GH.

Mol Microbiol. 2006 Aug;61(3):655-74. Epub 2006 Jun 27.

30.

Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds.

Cheng WP, Gray AI, Tetley L, Hang Tle B, Schätzlein AG, Uchegbu IF.

Biomacromolecules. 2006 May;7(5):1509-20.

PMID:
16677033
31.

Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes.

Helms MJ, Ambit A, Appleton P, Tetley L, Coombs GH, Mottram JC.

J Cell Sci. 2006 Mar 15;119(Pt 6):1105-17. Epub 2006 Feb 28.

32.

Tumour gene expression from C12 spermine amphiphile gene delivery systems.

Kan PL, Gray AI, Tetley L, Converse CA, Schätzlein AG, Uchegbu IF.

J Drug Target. 2005 Jul;13(6):345-57.

PMID:
16278154
33.

Gene transfer with three amphiphilic glycol chitosans--the degree of polymerisation is the main controller of transfection efficiency.

Uchegbu IF, Sadiq L, Pardakhty A, El-Hammadi M, Gray AI, Tetley L, Wang W, Zinselmeyer BH, Schätzlein AG.

J Drug Target. 2004;12(8):527-39.

PMID:
15621678
34.

Vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles.

Brewer JM, Pollock KG, Tetley L, Russell DG.

J Immunol. 2004 Nov 15;173(10):6143-50.

35.
36.

Characterization of a mitochondrion-like organelle in Cryptosporidium parvum.

Putignani L, Tait A, Smith HV, Horner D, Tovar J, Tetley L, Wastling JM.

Parasitology. 2004 Jul;129(Pt 1):1-18.

PMID:
15267107
37.

Optimisation of a lipid based oral delivery system containing A/Panama influenza haemagglutinin.

Mann JF, Ferro VA, Mullen AB, Tetley L, Mullen M, Carter KC, Alexander J, Stimson WH.

Vaccine. 2004 Jun 23;22(19):2425-9.

PMID:
15193405
38.

The effects of a mutant connexin 26 on epidermal differentiation.

Bakirtzis G, Jamieson S, Aasen T, Bryson S, Forrow S, Tetley L, Finbow M, Greenhalgh D, Hodgins M.

Cell Commun Adhes. 2003 Jul-Dec;10(4-6):359-64.

PMID:
14681042
39.

In vitro and in vivo gene transfer with poly(amino acid) vesicles.

Brown MD, Gray AI, Tetley L, Santovena A, Rene J, Schätzlein AG, Uchegbu IF.

J Control Release. 2003 Dec 5;93(2):193-211.

PMID:
14636725
40.

Targeted epidermal expression of mutant Connexin 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders.

Bakirtzis G, Choudhry R, Aasen T, Shore L, Brown K, Bryson S, Forrow S, Tetley L, Finbow M, Greenhalgh D, Hodgins M.

Hum Mol Genet. 2003 Jul 15;12(14):1737-44.

PMID:
12837696
41.

The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.

Martin L, Wilson CG, Koosha F, Tetley L, Gray AI, Senel S, Uchegbu IF.

J Control Release. 2002 Apr 23;80(1-3):87-100.

PMID:
11943390
43.

Temperature is a cue for gene expression in the post-infective L3 of the parasitic nematode Brugia pahangi.

Hunter SJ, Thompson FJ, Tetley L, Devaney E.

Mol Biochem Parasitol. 2001 Jan 15;112(1):1-9.

PMID:
11166381
44.

Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting.

Dufes C, Schätzlein AG, Tetley L, Gray AI, Watson DG, Olivier JC, Couet W, Uchegbu IF.

Pharm Res. 2000 Oct;17(10):1250-8.

45.

Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents.

Brown MD, Schätzlein A, Brownlie A, Jack V, Wang W, Tetley L, Gray AI, Uchegbu IF.

Bioconjug Chem. 2000 Nov-Dec;11(6):880-91.

PMID:
11087338
46.

Processing and trafficking of cysteine proteases in Leishmania mexicana.

Brooks DR, Tetley L, Coombs GH, Mottram JC.

J Cell Sci. 2000 Nov;113 ( Pt 22):4035-41.

47.

Liposomes encapsulating polymeric chitosan based vesicles--a vesicle in vesicle system for drug delivery.

McPhail D, Tetley L, Dufes C, Uchegbu IF.

Int J Pharm. 2000 Apr 25;200(1):73-86.

PMID:
10845688
48.
49.

The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi.

Hunter SJ, Martin SA, Thompson FJ, Tetley L, Devaney E.

Parasitology. 1999 Aug;119 ( Pt 2):189-98.

PMID:
10466127
50.

cut-1-like genes are present in the filarial nematodes, Brugia pahangi and Brugia malayi, and, as in other nematodes, code for components of the cuticle.

Lewis E, Hunter SJ, Tetley L, Nunes CP, Bazzicalupo P, Devaney E.

Mol Biochem Parasitol. 1999 Jun 25;101(1-2):173-83.

PMID:
10413052

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