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Items: 1 to 50 of 155

1.

SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia.

Bon C, Luffarelli R, Russo R, Fortuni S, Pierattini B, Santulli C, Fimiani C, Persichetti F, Cotella D, Mallamaci A, Santoro C, Carninci P, Espinoza S, Testi R, Zucchelli S, Condò I, Gustincich S.

Nucleic Acids Res. 2019 Nov 18;47(20):10728-10743. doi: 10.1093/nar/gkz798.

PMID:
31584077
2.

Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia.

Alfedi G, Luffarelli R, Condò I, Pedini G, Mannucci L, Massaro DS, Benini M, Toschi N, Alaimo G, Panarello L, Pacini L, Fortuni S, Serio D, Malisan F, Testi R, Rufini A.

Mov Disord. 2019 Mar;34(3):323-334. doi: 10.1002/mds.27604. Epub 2019 Jan 9.

PMID:
30624801
3.

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene.

Di Fede G, Catania M, Atzori C, Moda F, Pasquali C, Indaco A, Grisoli M, Zuffi M, Guaita MC, Testi R, Taraglio S, Sessa M, Gusmaroli G, Spinelli M, Salzano G, Legname G, Tarletti R, Godi L, Pocchiari M, Tagliavini F, Imperiale D, Giaccone G.

Acta Neuropathol Commun. 2019 Jan 3;7(1):1. doi: 10.1186/s40478-018-0656-4.

4.

Biophysical characterisation of the recombinant human frataxin precursor.

Castro IH, Ferrari A, Herrera MG, Noguera ME, Maso L, Benini M, Rufini A, Testi R, Costantini P, Santos J.

FEBS Open Bio. 2018 Jan 25;8(3):390-405. doi: 10.1002/2211-5463.12376. eCollection 2018 Mar.

5.

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia.

Benini M, Fortuni S, Condò I, Alfedi G, Malisan F, Toschi N, Serio D, Massaro DS, Arcuri G, Testi R, Rufini A.

Cell Rep. 2017 Feb 21;18(8):2007-2017. doi: 10.1016/j.celrep.2017.01.079.

6.

Analyzing the Effects of a G137V Mutation in the FXN Gene.

Faggianelli N, Puglisi R, Veneziano L, Romano S, Frontali M, Vannocci T, Fortuni S, Testi R, Pastore A.

Front Mol Neurosci. 2015 Nov 25;8:66. doi: 10.3389/fnmol.2015.00066. eCollection 2015.

7.

GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNγ administration in FRDA patients.

Marcotulli C, Fortuni S, Arcuri G, Tomassini B, Leonardi L, Pierelli F, Testi R, Casali C.

Neurol Sci. 2016 Mar;37(3):361-4. doi: 10.1007/s10072-015-2427-3. Epub 2015 Nov 30.

PMID:
26621361
8.

A Biological and Procedural Review of Forensically Significant Dermestes Species (Coleoptera: Dermestidae).

Magni PA, Voss SC, Testi R, Borrini M, Dadour IR.

J Med Entomol. 2015 Sep;52(5):755-69. doi: 10.1093/jme/tjv106. Epub 2015 Jul 25. Review.

PMID:
26336246
9.

Evaluation of DNA typing as a positive identification method for soft and hard tissues immersed in strong acids.

Robino C, Pazzi M, Di Vella G, Martinelli D, Mazzola L, Ricci U, Testi R, Vincenti M.

Leg Med (Tokyo). 2015 Nov;17(6):569-75. doi: 10.1016/j.legalmed.2015.07.004. Epub 2015 Jul 14.

10.

Anemia and hemoglobin serum levels are associated with exercise capacity and quality of life in chronic obstructive pulmonary disease.

Ferrari M, Manea L, Anton K, Bruzzone P, Meneghello M, Zamboni F, Purgato L, Cazzoletti L, Ferrari P, Testi R.

BMC Pulm Med. 2015 May 8;15:58. doi: 10.1186/s12890-015-0050-y.

11.

Src inhibitors modulate frataxin protein levels.

Cherubini F, Serio D, Guccini I, Fortuni S, Arcuri G, Condò I, Rufini A, Moiz S, Camerini S, Crescenzi M, Testi R, Malisan F.

Hum Mol Genet. 2015 Aug 1;24(15):4296-305. doi: 10.1093/hmg/ddv162. Epub 2015 May 6.

PMID:
25948553
12.

Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells.

Rufini A, Cavallo F, Condò I, Fortuni S, De Martino G, Incani O, Di Venere A, Benini M, Massaro DS, Arcuri G, Serio D, Malisan F, Testi R.

Neurobiol Dis. 2015 Mar;75:91-9. doi: 10.1016/j.nbd.2014.12.011. Epub 2014 Dec 27.

13.

Diffuse leukoencephalopathy due to lymphomatosis cerebri: a clinicopathological report.

Imperiale D, Taraglio S, Atzori C, Testi R.

Neurol Sci. 2015 Jun;36(6):1071-3. doi: 10.1007/s10072-014-1974-3. Epub 2014 Oct 29. No abstract available.

PMID:
25351342
14.

Clinical and neuropathological findings in Hashimoto's encephalopathy: a case report.

Imperiale D, Labate C, Testi R, Romito A, Taraglio S.

Neurol Sci. 2014 Feb;35(2):327-9. doi: 10.1007/s10072-013-1554-y. Epub 2013 Sep 24. No abstract available.

PMID:
24062213
15.

The level of control of mild asthma in general practice: an observational community-based study.

Caminati M, Bettoncelli G, Magnoni MS, Rizzi A, Testi R, Passalacqua G, De Marco R, Caramori G, Senna G.

J Asthma. 2014 Feb;51(1):91-6. doi: 10.3109/02770903.2013.843098. Epub 2013 Oct 9.

PMID:
24040887
16.

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans.

Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, Testi R, Ventura N.

Exp Gerontol. 2013 Feb;48(2):191-201. doi: 10.1016/j.exger.2012.12.002. Epub 2012 Dec 13. Erratum in: Exp Gerontol. 2013 Sep;48(9):1001.

17.

Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model.

Tomassini B, Arcuri G, Fortuni S, Sandi C, Ezzatizadeh V, Casali C, Condò I, Malisan F, Al-Mahdawi S, Pook M, Testi R.

Hum Mol Genet. 2012 Jul 1;21(13):2855-61. doi: 10.1093/hmg/dds110. Epub 2012 Mar 23.

18.

Frataxin participates to the hypoxia-induced response in tumors.

Guccini I, Serio D, Condò I, Rufini A, Tomassini B, Mangiola A, Maira G, Anile C, Fina D, Pallone F, Mongiardi MP, Levi A, Ventura N, Testi R, Malisan F.

Cell Death Dis. 2011 Feb 24;2:e123. doi: 10.1038/cddis.2011.5.

19.

Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia.

Rufini A, Fortuni S, Arcuri G, Condò I, Serio D, Incani O, Malisan F, Ventura N, Testi R.

Hum Mol Genet. 2011 Apr 1;20(7):1253-61. doi: 10.1093/hmg/ddq566. Epub 2011 Jan 7.

PMID:
21216878
20.

A role for p53 in mitochondrial stress response control of longevity in C. elegans.

Torgovnick A, Schiavi A, Testi R, Ventura N.

Exp Gerontol. 2010 Aug;45(7-8):550-7. doi: 10.1016/j.exger.2010.02.007. Epub 2010 Feb 19.

PMID:
20172019
21.

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

Condò I, Malisan F, Guccini I, Serio D, Rufini A, Testi R.

Hum Mol Genet. 2010 Apr 1;19(7):1221-9. doi: 10.1093/hmg/ddp592. Epub 2010 Jan 6.

PMID:
20053667
22.

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress.

Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE.

Aging Cell. 2009 Aug;8(4):380-93. doi: 10.1111/j.1474-9726.2009.00482.x. Epub 2009 Apr 22.

23.

Multifocal necrotizing leukoencephalopathy mimicking sporadic Creutzfeldt-Jakob disease.

Imperiale D, Taraglio S, Atzori C, Testi R, Buffa C, Migheli A.

Eur Neurol. 2008;59(6):327-9. doi: 10.1159/000121425. Epub 2008 Apr 11. No abstract available.

24.

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Stagni V, di Bari MG, Cursi S, Condò I, Cencioni MT, Testi R, Lerenthal Y, Cundari E, Barilà D.

Blood. 2008 Jan 15;111(2):829-37. Epub 2007 Oct 11.

PMID:
17932249
25.

Molecular detection of GNNK- and GNNK+ c-kit isoforms: a new tool for risk stratification in adult acute myeloid leukaemia.

Guerrini F, Galimberti S, Ciabatti E, Brizzi S, Testi R, Pollastrini A, Falini B, Petrini M.

Leukemia. 2007 Sep;21(9):2056-8. Epub 2007 Jun 7. No abstract available.

PMID:
17554388
26.

Acid reflux into the oesophagus does not influence exercise-induced airway narrowing in bronchial asthma.

Ferrari M, Bonella F, Benini L, Ferrari P, De Iorio F, Testi R, Lo Cascio V.

Br J Sports Med. 2008 Oct;42(10):845-9; discussion 849-50. Epub 2007 Jun 1. Erratum in: Br J Sports Med. 2009 Apr;43(4):310-1.

PMID:
17545276
27.

In vivo maturation of human frataxin.

Condò I, Ventura N, Malisan F, Rufini A, Tomassini B, Testi R.

Hum Mol Genet. 2007 Jul 1;16(13):1534-40. Epub 2007 Apr 27.

PMID:
17468497
28.

Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases.

Ventura N, Rea SL, Testi R.

Exp Gerontol. 2006 Oct;41(10):974-91. Epub 2006 Sep 1. Review.

PMID:
16945497
29.

5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death.

Fina D, Franchi L, Caruso R, Peluso I, Naccari GC, Bellinvia S, Testi R, Pallone F, Monteleone G.

Eur J Cancer. 2006 Oct;42(15):2609-16. Epub 2006 Aug 17.

PMID:
16914308
30.

C. elegans as a model for Friedreich Ataxia.

Ventura N, Rea SL, Handerson ST, Condò I, Testi R, Johnson TE.

FASEB J. 2006 May;20(7):1029-30. No abstract available.

PMID:
16675853
31.

c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization.

di Bari MG, Ciuffini L, Mingardi M, Testi R, Soddu S, Barilà D.

EMBO Rep. 2006 Jul;7(7):727-33. Epub 2006 Apr 28.

32.

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression.

Cursi S, Rufini A, Stagni V, Condò I, Matafora V, Bachi A, Bonifazi AP, Coppola L, Superti-Furga G, Testi R, Barilà D.

EMBO J. 2006 May 3;25(9):1895-905. Epub 2006 Apr 13.

33.

A pool of extramitochondrial frataxin that promotes cell survival.

Condò I, Ventura N, Malisan F, Tomassini B, Testi R.

J Biol Chem. 2006 Jun 16;281(24):16750-6. Epub 2006 Apr 11.

34.

9-O-acetyl GD3 protects tumor cells from apoptosis.

Kniep B, Kniep E, Ozkucur N, Barz S, Bachmann M, Malisan F, Testi R, Rieber EP.

Int J Cancer. 2006 Jul 1;119(1):67-73.

35.

Ceramide catabolism critically controls survival of human dendritic cells.

Franchi L, Malisan F, Tomassini B, Testi R.

J Leukoc Biol. 2006 Jan;79(1):166-72. Epub 2005 Oct 21.

PMID:
16244104
36.

Lung myofibroblasts as targets of salmeterol and fluticasone propionate: inhibition of alpha-SMA and NF-kappaB.

Baouz S, Giron-Michel J, Azzarone B, Giuliani M, Cagnoni F, Olsson S, Testi R, Gabbiani G, Canonica GW.

Int Immunol. 2005 Nov;17(11):1473-81. Epub 2005 Oct 6.

PMID:
16210331
37.

Quantitative molecular monitoring of BCR-ABL and MDR1 transcripts in patients with chronic myeloid leukemia during Imatinib treatment.

Galimberti S, Cervetti G, Guerrini F, Testi R, Pacini S, Fazzi R, Simi P, Petrini M.

Cancer Genet Cytogenet. 2005 Oct 1;162(1):57-62.

PMID:
16157201
38.

Nebulized fluticasone propionate vs. budesonide as adjunctive treatment in children with asthma exacerbation.

De Benedictis FM, Del Giudice MM, Vetrella M, Tressanti F, Tronci A, Testi R, Dasic G; Flic12 Study Group.

J Asthma. 2005 Jun;42(5):331-6.

PMID:
16116682
39.

Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells.

Monteleone G, Franchi L, Fina D, Caruso R, Vavassori P, Monteleone I, Calabrese E, Naccari GC, Bellinvia S, Testi R, Pallone F.

Cell Death Differ. 2006 Feb;13(2):202-11.

40.
41.

Inhaled corticosteroids are more effective in COPD patients when used with LABA than with SABA.

Kiri VA, Bettoncelli G, Testi R, Viegi G.

Respir Med. 2005 Sep;99(9):1115-24. Epub 2005 Mar 21.

42.

Exacerbations as a starting point of pro-active chronic obstructive pulmonary disease management.

Zoia MC, Corsico AG, Beccaria M, Guarnone R, Cervio G, Testi R, Bressan MA, Pozzi E, Cerveri I.

Respir Med. 2005 Dec;99(12):1568-75.

43.

Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans.

Ventura N, Rea S, Henderson ST, Condo I, Johnson TE, Testi R.

Aging Cell. 2005 Apr;4(2):109-12.

44.

Step-down compared to fixed-dose treatment with inhaled fluticasone propionate in asthma.

Foresi A, Mastropasqua B, Chetta A, D'Ippolito R, Testi R, Olivieri D, Pelucchi A.

Chest. 2005 Jan;127(1):117-24.

PMID:
15653971
45.

A comparison between inhaled salmeterol and theophylline in the short-term treatment of stable chronic obstructive pulmonary disease.

Broseghini C, Testi R, Polese G, Tosatto R, Rossi A.

Pulm Pharmacol Ther. 2005;18(2):103-8. Epub 2005 Jan 7.

PMID:
15649852
46.

Differential regulation of apoptotic cell death in senescent human cells.

Hampel B, Malisan F, Niederegger H, Testi R, Jansen-Dürr P.

Exp Gerontol. 2004 Nov-Dec;39(11-12):1713-21.

PMID:
15582287
47.

Calnexin suppresses GD3 synthase-induced apoptosis.

Tomassini B, Malisan F, Franchi L, Nicolò C, Calvo GB, Saito T, Testi R.

FASEB J. 2004 Oct;18(13):1553-5. Epub 2004 Aug 19.

PMID:
15319364
48.
49.

Expansion of TcRalphabeta+CD3+CD4-CD8- (CD4/CD8 double-negative) T lymphocytes in a case of staphylococcal toxic shock syndrome.

Carulli G, Lagomarsini G, Azzarà A, Testi R, Riccioni R, Petrini M.

Acta Haematol. 2004;111(3):163-7.

PMID:
15034239
50.

p21(Waf1/Cip1/Sdi1) mediates shear stress-dependent antiapoptotic function.

Mattiussi S, Turrini P, Testolin L, Martelli F, Zaccagnini G, Mangoni A, Barlucchi LM, Antonini A, Illi B, Cirielli C, Padron J, Nicolò C, Testi R, Osculati F, Biglioli P, Capogrossi MC, Gaetano C.

Cardiovasc Res. 2004 Mar 1;61(4):693-704.

PMID:
14985066

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