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Items: 12

1.

From association to mechanism in complex disease genetics: the role of the 3D genome.

Fu Y, Tessneer KL, Li C, Gaffney PM.

Arthritis Res Ther. 2018 Sep 29;20(1):216. doi: 10.1186/s13075-018-1721-x. Review.

2.

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

Pelikan RC, Kelly JA, Fu Y, Lareau CA, Tessneer KL, Wiley GB, Wiley MM, Glenn SB, Harley JB, Guthridge JM, James JA, Aryee MJ, Montgomery C, Gaffney PM.

Nat Commun. 2018 Jul 25;9(1):2905. doi: 10.1038/s41467-018-05328-9.

3.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2016 Apr 1;126(4):1607. doi: 10.1172/JCI87344. Epub 2016 Mar 21. No abstract available.

4.

Selective Targeting of a Novel Epsin-VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis.

Rahman HNA, Wu H, Dong Y, Pasula S, Wen A, Sun Y, Brophy ML, Tessneer KL, Cai X, McManus J, Chang B, Kwak S, Rahman NS, Xu W, Fernandes C, Mcdaniel JM, Xia L, Smith L, Srinivasan RS, Chen H.

Circ Res. 2016 Mar 18;118(6):957-969. doi: 10.1161/CIRCRESAHA.115.307679. Epub 2016 Feb 15.

5.

TALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus.

Wang S, Wen F, Tessneer KL, Gaffney PM.

Genes Immun. 2016 Apr;17(3):165-70. doi: 10.1038/gene.2016.4. Epub 2016 Jan 28.

6.

Motif mimetic of epsin perturbs tumor growth and metastasis.

Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H.

J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Epub 2015 Nov 16. Erratum in: J Clin Invest. 2016 Apr 1;126(4):1607.

7.

Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.

Chang B, Tessneer KL, McManus J, Liu X, Hahn S, Pasula S, Wu H, Song H, Chen Y, Cai X, Dong Y, Brophy ML, Rahman R, Ma JX, Xia L, Chen H.

Nat Commun. 2015 Mar 16;6:6380. doi: 10.1038/ncomms7380.

8.

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.

Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H.

Sci Signal. 2014 Oct 14;7(347):ra97. doi: 10.1126/scisignal.2005413.

9.

Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance.

Tessneer KL, Jackson RM, Griesel BA, Olson AL.

Endocrinology. 2014 Sep;155(9):3315-28. doi: 10.1210/en.2013-2148. Epub 2014 Jun 16.

10.

Epsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer Progression.

Tessneer KL, Cai X, Pasula S, Dong Y, Liu X, Chang B, McManus J, Hahn S, Yu L, Chen H.

J Can Res Updates. 2013 Jul 1;2(3):144-150.

11.

Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.

Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-337. doi: 10.1161/ATVBAHA.113.302586. Epub 2013 Dec 5. Erratum in: Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):e7.

12.

Endocytic adaptor protein epsin is elevated in prostate cancer and required for cancer progression.

Tessneer KL, Pasula S, Cai X, Dong Y, Liu X, Yu L, Hahn S, McManus J, Chen Y, Chang B, Chen H.

ISRN Oncol. 2013 Apr 4;2013:420597. doi: 10.1155/2013/420597. Print 2013.

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