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Items: 1 to 50 of 88

1.

Calcium Signaling in the Heart.

Terrar DA.

Adv Exp Med Biol. 2020;1131:395-443. doi: 10.1007/978-3-030-12457-1_16. Review.

PMID:
31646519
2.

Pnmt-Derived Cardiomyocytes: Anatomical Localization, Function and Future Perspectives.

Fan X, Sun T, Crawford W, Tan X, Ou X, Terrar DA, Ebert SN, Lei M.

Front Physiol. 2019 Jul 10;10:713. doi: 10.3389/fphys.2019.00713. eCollection 2019. Review.

3.

Response by Lei et al to Letter Regarding Article, "Modernized Classification of Cardiac Antiarrhythmic Drugs".

Lei M, Wu L, Terrar DA, Huang CL.

Circulation. 2019 Mar 26;139(13):1652-1653. doi: 10.1161/CIRCULATIONAHA.118.039292. No abstract available.

PMID:
30908105
4.

Modernized Classification of Cardiac Antiarrhythmic Drugs.

Lei M, Wu L, Terrar DA, Huang CL.

Circulation. 2018 Oct 23;138(17):1879-1896. doi: 10.1161/CIRCULATIONAHA.118.035455. Erratum in: Circulation. 2019 Mar 26;139(13):e635.

PMID:
30354657
5.

Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca2+ transients in murine heart.

Wen Q, Gandhi K, Capel RA, Hao G, O'Shea C, Neagu G, Pearcey S, Pavlovic D, Terrar DA, Wu J, Faggian G, Camelliti P, Lei M.

J Physiol. 2018 Sep;596(17):3951-3965. doi: 10.1113/JP276239. Epub 2018 Jul 26.

6.

Synthesis of the Ca2+-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling.

Lin WK, Bolton EL, Cortopassi WA, Wang Y, O'Brien F, Maciejewska M, Jacobson MP, Garnham C, Ruas M, Parrington J, Lei M, Sitsapesan R, Galione A, Terrar DA.

J Biol Chem. 2017 Aug 11;292(32):13243-13257. doi: 10.1074/jbc.M117.789347. Epub 2017 May 24.

7.

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Aston D, Capel RA, Ford KL, Christian HC, Mirams GR, Rog-Zielinska EA, Kohl P, Galione A, Burton RA, Terrar DA.

Sci Rep. 2017 Jan 17;7:40620. doi: 10.1038/srep40620.

8.

Optogenetic Control of Heart Rhythm by Selective Stimulation of Cardiomyocytes Derived from Pnmt+ Cells in Murine Heart.

Wang Y, Lin WK, Crawford W, Ni H, Bolton EL, Khan H, Shanks J, Bub G, Wang X, Paterson DJ, Zhang H, Galione A, Ebert SN, Terrar DA, Lei M.

Sci Rep. 2017 Jan 13;7:40687. doi: 10.1038/srep40687.

9.

Contributions of cardiac "funny" (f) channels and sarcoplasmic reticulum Ca2+ in regulating beating rate of mouse and guinea pig sinoatrial node.

Nazarov IB, Schofield CJ, Terrar DA.

Physiol Rep. 2015 Dec;3(12). pii: e12561. doi: 10.14814/phy2.12561.

10.

Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart.

Capel RA, Bolton EL, Lin WK, Aston D, Wang Y, Liu W, Wang X, Burton RA, Bloor-Young D, Shade KT, Ruas M, Parrington J, Churchill GC, Lei M, Galione A, Terrar DA.

J Biol Chem. 2015 Dec 11;290(50):30087-98. doi: 10.1074/jbc.M115.684076. Epub 2015 Oct 5.

11.

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential.

Capel RA, Herring N, Kalla M, Yavari A, Mirams GR, Douglas G, Bub G, Channon K, Paterson DJ, Terrar DA, Burton RA.

Heart Rhythm. 2015 Oct;12(10):2186-94. doi: 10.1016/j.hrthm.2015.05.027. Epub 2015 May 27.

12.

The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat.

Capel RA, Terrar DA.

Front Physiol. 2015 Mar 25;6:80. doi: 10.3389/fphys.2015.00080. eCollection 2015. Review.

13.

Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node.

Capel RA, Terrar DA.

Front Physiol. 2015 Feb 10;6:23. doi: 10.3389/fphys.2015.00023. eCollection 2015.

14.

Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M.

Circ Arrhythm Electrophysiol. 2014 Oct;7(5):938-48. doi: 10.1161/CIRCEP.113.001198. Epub 2014 Sep 12.

15.

Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide.

Wang R, Wang Y, Lin WK, Zhang Y, Liu W, Huang K, Terrar DA, Solaro RJ, Wang X, Ke Y, Lei M.

PLoS One. 2014 Jul 11;9(7):e101974. doi: 10.1371/journal.pone.0101974. eCollection 2014.

16.

Cardiac electrophysiological imaging systems scalable for high-throughput drug testing.

Lee P, Wang K, Woods CE, Yan P, Kohl P, Ewart P, Loew LM, Terrar DA, Bollensdorff C.

Pflugers Arch. 2012 Dec;464(6):645-56. doi: 10.1007/s00424-012-1149-0. Epub 2012 Sep 29.

17.

β-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart.

Lewis AM, Aley PK, Roomi A, Thomas JM, Masgrau R, Garnham C, Shipman K, Paramore C, Bloor-Young D, Sanders LE, Terrar DA, Galione A, Churchill GC.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):326-9. doi: 10.1016/j.bbrc.2012.09.054. Epub 2012 Sep 18.

PMID:
22995315
18.

Ca(2+)-stimulated adenylyl cyclases regulate the L-type Ca(2+) current in guinea-pig atrial myocytes.

Collins TP, Terrar DA.

J Physiol. 2012 Apr 15;590(8):1881-93. doi: 10.1113/jphysiol.2011.227066. Epub 2012 Feb 20.

19.

NAADP influences excitation-contraction coupling by releasing calcium from lysosomes in atrial myocytes.

Collins TP, Bayliss R, Churchill GC, Galione A, Terrar DA.

Cell Calcium. 2011 Nov;50(5):449-58. doi: 10.1016/j.ceca.2011.07.007. Epub 2011 Sep 8.

PMID:
21906808
20.

Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization.

Terrar DA, Wilson CM, Graham SG, Bryant SM, Heath BM.

J Pharmacol Toxicol Methods. 2007 Sep-Oct;56(2):171-85. Epub 2007 May 26.

PMID:
17596973
21.

Regulation of L-type calcium channel and delayed rectifier potassium channel activity by p21-activated kinase-1 in guinea pig sinoatrial node pacemaker cells.

Ke Y, Lei M, Collins TP, Rakovic S, Mattick PA, Yamasaki M, Brodie MS, Terrar DA, Solaro RJ.

Circ Res. 2007 May 11;100(9):1317-27. Epub 2007 Apr 5.

PMID:
17413045
22.

NAADP controls cross-talk between distinct Ca2+ stores in the heart.

Macgregor A, Yamasaki M, Rakovic S, Sanders L, Parkesh R, Churchill GC, Galione A, Terrar DA.

J Biol Chem. 2007 May 18;282(20):15302-11. Epub 2007 Mar 26.

23.

Dual effects of cyclic ADP-ribose on sarcoplasmic reticulum Ca2+ release and storage in cardiac myocytes isolated from guinea-pig and rat ventricle.

Macgregor AT, Rakovic S, Galione A, Terrar DA.

Cell Calcium. 2007 Jun;41(6):537-46. Epub 2006 Dec 5.

PMID:
17156839
24.

Fundamental importance of Na+-Ca2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node.

Sanders L, Rakovic S, Lowe M, Mattick PA, Terrar DA.

J Physiol. 2006 Mar 15;571(Pt 3):639-49. Epub 2006 Jan 19.

25.

Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.

Sears CE, Bryant SM, Ashley EA, Lygate CA, Rakovic S, Wallis HL, Neubauer S, Terrar DA, Casadei B.

Circ Res. 2003 Mar 21;92(5):e52-9. Epub 2003 Mar 6.

PMID:
12623875
26.

Modulation of the hyperpolarization-activated current (I(f)) by calcium and calmodulin in the guinea-pig sino-atrial node.

Rigg L, Mattick PA, Heath BM, Terrar DA.

Cardiovasc Res. 2003 Feb;57(2):497-504.

PMID:
12566122
27.

NO-cGMP pathway increases the hyperpolarisation-activated current, I(f), and heart rate during adrenergic stimulation.

Herring N, Rigg L, Terrar DA, Paterson DJ.

Cardiovasc Res. 2001 Dec;52(3):446-53.

PMID:
11738061
28.
29.
30.
31.
32.

Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors.

Musialek P, Rigg L, Terrar DA, Paterson DJ, Casadei B.

J Mol Cell Cardiol. 2000 Oct;32(10):1831-40.

PMID:
11013127
34.
36.

An antagonist of cADP-ribose inhibits arrhythmogenic oscillations of intracellular Ca2+ in heart cells.

Rakovic S, Cui Y, Iino S, Galione A, Ashamu GA, Potter BV, Terrar DA.

J Biol Chem. 1999 Jun 18;274(25):17820-7.

37.
38.

Block by propofol and thiopentone of the min K current (IsK) expressed in Xenopus oocytes.

Heath BM, Terrar DA.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):404-9.

PMID:
9303580
40.

A specific cyclic ADP-ribose antagonist inhibits cardiac excitation-contraction coupling.

Rakovic S, Galione A, Ashamu GA, Potter BV, Terrar DA.

Curr Biol. 1996 Aug 1;6(8):989-96.

43.

Effects of caffeine on background potassium current in isolated guinea pig ventricular myocytes.

Cui Y, Terrar DA.

J Cardiovasc Pharmacol. 1995 May;25(5):691-5.

PMID:
7630146
46.
47.
48.

Structure and function of calcium channels and the actions of anaesthetics.

Terrar DA.

Br J Anaesth. 1993 Jul;71(1):39-46. Review. No abstract available.

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