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Items: 1 to 50 of 113

1.

Diagnostic Targeted Sequencing Panel for Hepatocellular Carcinoma Genomic Screening.

Paradiso V, Garofoli A, Tosti N, Lanzafame M, Perrina V, Quagliata L, Matter MS, Wieland S, Heim MH, Piscuoglio S, Ng CKY, Terracciano LM.

J Mol Diagn. 2018 Aug 22. pii: S1525-1578(18)30025-4. doi: 10.1016/j.jmoldx.2018.07.003. [Epub ahead of print]

PMID:
30142445
2.

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.

Nuciforo S, Fofana I, Matter MS, Blumer T, Calabrese D, Boldanova T, Piscuoglio S, Wieland S, Ringnalda F, Schwank G, Terracciano LM, Ng CKY, Heim MH.

Cell Rep. 2018 Jul 31;24(5):1363-1376. doi: 10.1016/j.celrep.2018.07.001.

3.

Circulating Cell-Free DNA in Hepatocellular Carcinoma: Current Insights and Outlook.

Ng CKY, Di Costanzo GG, Terracciano LM, Piscuoglio S.

Front Med (Lausanne). 2018 Mar 26;5:78. doi: 10.3389/fmed.2018.00078. eCollection 2018. Review.

4.

The protein histidine phosphatase LHPP is a tumour suppressor.

Hindupur SK, Colombi M, Fuhs SR, Matter MS, Guri Y, Adam K, Cornu M, Piscuoglio S, Ng CKY, Betz C, Liko D, Quagliata L, Moes S, Jenoe P, Terracciano LM, Heim MH, Hunter T, Hall MN.

Nature. 2018 Mar 29;555(7698):678-682. doi: 10.1038/nature26140. Epub 2018 Mar 21.

PMID:
29562234
5.

Genetic profiling using plasma-derived cell-free DNA in therapy-naïve hepatocellular carcinoma patients: a pilot study.

Ng CKY, Di Costanzo GG, Tosti N, Paradiso V, Coto-Llerena M, Roscigno G, Perrina V, Quintavalle C, Boldanova T, Wieland S, Marino-Marsilia G, Lanzafame M, Quagliata L, Condorelli G, Matter MS, Tortora R, Heim MH, Terracciano LM, Piscuoglio S.

Ann Oncol. 2018 May 1;29(5):1286-1291. doi: 10.1093/annonc/mdy083.

PMID:
29509837
6.

The Role of Long Non-Coding RNAs in Hepatocarcinogenesis.

Lanzafame M, Bianco G, Terracciano LM, Ng CKY, Piscuoglio S.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E682. doi: 10.3390/ijms19030682. Review.

7.

Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma.

Kancherla V, Abdullazade S, Matter MS, Lanzafame M, Quagliata L, Roma G, Hoshida Y, Terracciano LM, Ng CKY, Piscuoglio S.

Front Genet. 2018 Feb 2;9:2. doi: 10.3389/fgene.2018.00002. eCollection 2018.

8.

Gut microbiota modulate T cell trafficking into human colorectal cancer.

Cremonesi E, Governa V, Garzon JFG, Mele V, Amicarella F, Muraro MG, Trella E, Galati-Fournier V, Oertli D, Däster SR, Droeser RA, Weixler B, Bolli M, Rosso R, Nitsche U, Khanna N, Egli A, Keck S, Slotta-Huspenina J, Terracciano LM, Zajac P, Spagnoli GC, Eppenberger-Castori S, Janssen KP, Borsig L, Iezzi G.

Gut. 2018 Feb 6. pii: gutjnl-2016-313498. doi: 10.1136/gutjnl-2016-313498. [Epub ahead of print]

PMID:
29437871
9.

In vivo analysis at the cellular level reveals similar steatosis induction in both hepatitis C virus genotype 1 and 3 infections.

Campana B, Calabrese D, Matter MS, Terracciano LM, Wieland SF, Heim MH.

J Viral Hepat. 2018 Mar;25(3):262-271. doi: 10.1111/jvh.12816. Epub 2017 Nov 20.

PMID:
29086446
10.

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer.

Mele V, Sokol L, Kölzer VH, Pfaff D, Muraro MG, Keller I, Stefan Z, Centeno I, Terracciano LM, Dawson H, Zlobec I, Iezzi G, Lugli A.

Oncotarget. 2017 Aug 3;8(41):70617-70629. doi: 10.18632/oncotarget.19904. eCollection 2017 Sep 19.

11.

High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models.

Quagliata L, Quintavalle C, Lanzafame M, Matter MS, Novello C, di Tommaso L, Pressiani T, Rimassa L, Tornillo L, Roncalli M, Cillo C, Pallante P, Piscuoglio S, Ng CK, Terracciano LM.

Lab Invest. 2018 Jan;98(1):95-105. doi: 10.1038/labinvest.2017.107. Epub 2017 Oct 16.

PMID:
29035381
12.

Molecular classification of hepatocellular carcinoma: The view from metabolic zonation.

Ng CKY, Piscuoglio S, Terracciano LM.

Hepatology. 2017 Nov;66(5):1377-1380. doi: 10.1002/hep.29311. Epub 2017 Sep 29. No abstract available.

PMID:
28599064
13.

High mobility group A1 enhances tumorigenicity of human cholangiocarcinoma and confers resistance to therapy.

Quintavalle C, Burmeister K, Piscuoglio S, Quagliata L, Karamitopoulou E, Sepe R, Fusco A, Terracciano LM, Andersen JB, Pallante P, Matter MS.

Mol Carcinog. 2017 Sep;56(9):2146-2157. doi: 10.1002/mc.22671. Epub 2017 May 17.

PMID:
28467612
14.

Vascular endothelial growth factor A amplification in colorectal cancer is associated with reduced M1 and M2 macrophages and diminished PD-1-expressing lymphocytes.

Burmeister K, Quagliata L, Andreozzi M, Eppenberger-Castori S, Matter MS, Perrina V, Grobholz R, Jochum W, Horber D, Moosmann P, Lehmann F, Köberle D, Ng CK, Piscuoglio S, Tornillo L, Terracciano LM.

PLoS One. 2017 Apr 12;12(4):e0175563. doi: 10.1371/journal.pone.0175563. eCollection 2017.

15.

Down-regulation of hepatocyte nuclear factor-4α and defective zonation in livers expressing mutant Z α1-antitrypsin.

Piccolo P, Annunziata P, Soria LR, Attanasio S, Barbato A, Castello R, Carissimo A, Quagliata L, Terracciano LM, Brunetti-Pierri N.

Hepatology. 2017 Jul;66(1):124-135. doi: 10.1002/hep.29160. Epub 2017 May 27.

PMID:
28295475
16.

The Interplay Between Neutrophils and CD8+ T Cells Improves Survival in Human Colorectal Cancer.

Governa V, Trella E, Mele V, Tornillo L, Amicarella F, Cremonesi E, Muraro MG, Xu H, Droeser R, Däster SR, Bolli M, Rosso R, Oertli D, Eppenberger-Castori S, Terracciano LM, Iezzi G, Spagnoli GC.

Clin Cancer Res. 2017 Jul 15;23(14):3847-3858. doi: 10.1158/1078-0432.CCR-16-2047. Epub 2017 Jan 20.

17.

Liver damage and senescence increases in patients developing hepatocellular carcinoma.

Rey S, Quintavalle C, Burmeister K, Calabrese D, Schlageter M, Quagliata L, Cathomas G, Diebold J, Molinolo A, Heim MH, Terracciano LM, Matter MS.

J Gastroenterol Hepatol. 2017 Aug;32(8):1480-1486. doi: 10.1111/jgh.13717.

PMID:
28052383
18.

HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models.

Andreozzi M, Quintavalle C, Benz D, Quagliata L, Matter M, Calabrese D, Tosti N, Ruiz C, Trapani F, Tornillo L, Fusco A, Heim MH, Ng CK, Pallante P, Terracciano LM, Piscuoglio S.

Neoplasia. 2016 Dec;18(12):724-731. doi: 10.1016/j.neo.2016.10.002. Epub 2016 Nov 14.

19.

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 Oct 27;18(11):1260. doi: 10.1038/ncb3428. No abstract available.

PMID:
27784900
20.

Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.

Themanns M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracciano LM, Han X, Kenner L, Wagner KU, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R.

Sci Rep. 2016 Oct 7;6:34719. doi: 10.1038/srep34719.

21.

Affinity for self antigen selects Treg cells with distinct functional properties.

Wyss L, Stadinski BD, King CG, Schallenberg S, McCarthy NI, Lee JY, Kretschmer K, Terracciano LM, Anderson G, Surh CD, Huseby ES, Palmer E.

Nat Immunol. 2016 Sep;17(9):1093-101. doi: 10.1038/ni.3522. Epub 2016 Aug 1.

22.

RNASeq analysis reveals biological processes governing the clinical behaviour of endometrioid and serous endometrial cancers.

Lemetre C, Vieites B, Ng CK, Piscuoglio S, Schultheis AM, Marchiò C, Murali R, Lopez-García MA, Palacios JC, Jungbluth AA, Terracciano LM, Reis-Filho JS, Weigelt B.

Eur J Cancer. 2016 Sep;64:149-58. doi: 10.1016/j.ejca.2016.05.028. Epub 2016 Jul 14.

23.

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 May;18(5):467-79. doi: 10.1038/ncb3337. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2016 Oct 27;18(11):1260.

PMID:
27088858
24.

Hepatic adenomas with synchronous or metachronous fibrolamellar carcinomas: both are characterized by LFABP loss.

Graham RP, Terracciano LM, Meves A, Vanderboom PM, Dasari S, Yeh MM, Torbenson MS, Cruise MW.

Mod Pathol. 2016 Jun;29(6):607-15. doi: 10.1038/modpathol.2016.59. Epub 2016 Mar 25.

25.

Human Papillomavirus (HPV) Detection in Cytologic Specimens: Similarities and Differences of Available Methodology.

Bihl MP, Tornillo L, Kind AB, Obermann E, Noppen C, Chaffard R, Wynne P, Grilli B, Foerster A, Terracciano LM, Hoeller S.

Appl Immunohistochem Mol Morphol. 2017 Mar;25(3):184-189. doi: 10.1097/PAI.0000000000000290.

26.

Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention.

Witzigmann D, Quagliata L, Schenk SH, Quintavalle C, Terracciano LM, Huwyler J.

Hepatol Res. 2016 Jun;46(7):686-96. doi: 10.1111/hepr.12599. Epub 2015 Oct 29.

PMID:
26422581
27.

High intratumoral FOXP3⁺ T regulatory cell (Tregs) density is an independent good prognosticator in nodal negative colorectal cancer.

Hanke T, Melling N, Simon R, Sauter G, Bokemeyer C, Lebok P, Terracciano LM, Izbicki JR, Marx AH.

Int J Clin Exp Pathol. 2015 Jul 1;8(7):8227-35. eCollection 2015.

28.

Expression of phospho-mTOR kinase is abundant in colorectal cancer and associated with left-sided tumor localization.

Melling N, Simon R, Izbicki JR, Terracciano LM, Bokemeyer C, Sauter G, Marx AH.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):7009-15. eCollection 2015.

29.

HMGA1 overexpression is associated with a particular subset of human breast carcinomas.

Sepe R, Piscuoglio S, Quintavalle C, Perrina V, Quagliata L, Formisano U, Terracciano LM, Fusco A, Pallante P.

J Clin Pathol. 2016 Feb;69(2):117-21. doi: 10.1136/jclinpath-2015-202907. Epub 2015 Aug 6.

PMID:
26251519
30.

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Marti P, Stein C, Blumer T, Abraham Y, Dill MT, Pikiolek M, Orsini V, Jurisic G, Megel P, Makowska Z, Agarinis C, Tornillo L, Bouwmeester T, Ruffner H, Bauer A, Parker CN, Schmelzle T, Terracciano LM, Heim MH, Tchorz JS.

Hepatology. 2015 Nov;62(5):1497-510. doi: 10.1002/hep.27992. Epub 2015 Aug 25.

PMID:
26173433
31.

Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α).

Svensson K, Schnyder S, Albert V, Cardel B, Quagliata L, Terracciano LM, Handschin C.

J Biol Chem. 2015 Jun 26;290(26):16059-76. doi: 10.1074/jbc.M114.590653. Epub 2015 May 18.

32.

Status of estrogen receptor 1 (ESR1) gene in mastopathy predicts subsequent development of breast cancer.

Soysal SD, Kilic IB, Regenbrecht CR, Schneider S, Muenst S, Kilic N, Güth U, Dietel M, Terracciano LM, Kilic E.

Breast Cancer Res Treat. 2015 Jun;151(3):709-15. doi: 10.1007/s10549-015-3427-y. Epub 2015 May 16.

PMID:
25981900
33.

Loss of RNA-binding motif protein 3 expression is associated with right-sided localization and poor prognosis in colorectal cancer.

Melling N, Simon R, Mirlacher M, Izbicki JR, Stahl P, Terracciano LM, Bokemeyer C, Sauter G, Marx AH.

Histopathology. 2016 Jan;68(2):191-8. doi: 10.1111/his.12726. Epub 2015 Jul 22.

PMID:
25922889
34.

Liver Diseases and Long Non-Coding RNAs: New Insight and Perspective.

Quagliata L, Terracciano LM.

Front Med (Lausanne). 2014 Oct 17;1:35. doi: 10.3389/fmed.2014.00035. eCollection 2014. Review.

35.

Histopathology of hepatocellular carcinoma.

Schlageter M, Terracciano LM, D'Angelo S, Sorrentino P.

World J Gastroenterol. 2014 Nov 21;20(43):15955-64. doi: 10.3748/wjg.v20.i43.15955. Review.

36.

Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma.

Lehmann FS, Trapani F, Fueglistaler I, Terracciano LM, von Flüe M, Cathomas G, Zettl A, Benkert P, Oertli D, Beglinger C.

World J Gastroenterol. 2014 May 7;20(17):4994-9. doi: 10.3748/wjg.v20.i17.4994.

37.

Identification of New Players in Hepatocarcinogenesis: Limits and Opportunities of Using Tissue Microarray (TMA).

Quagliata L, Schlageter M, Quintavalle C, Tornillo L, Terracciano LM.

Microarrays (Basel). 2014 Apr 15;3(2):91-102. doi: 10.3390/microarrays3020091. Review.

38.

SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules.

Quagliata L, Andreozzi M, Kovac M, Tornillo L, Makowska Z, Moretti F, Heim MH, Heinimann K, Piscuoglio S, Terracciano LM.

Eur J Cancer. 2014 Mar;50(4):731-8. doi: 10.1016/j.ejca.2013.11.018. Epub 2013 Dec 3.

PMID:
24315626
39.

Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients.

Quagliata L, Matter MS, Piscuoglio S, Arabi L, Ruiz C, Procino A, Kovac M, Moretti F, Makowska Z, Boldanova T, Andersen JB, Hämmerle M, Tornillo L, Heim MH, Diederichs S, Cillo C, Terracciano LM.

Hepatology. 2014 Mar;59(3):911-23. doi: 10.1002/hep.26740. Epub 2014 Jan 28.

40.

VEGFA gene locus analysis across 80 human tumour types reveals gene amplification in several neoplastic entities.

Andreozzi M, Quagliata L, Gsponer JR, Ruiz C, Vuaroqueaux V, Eppenberger-Castori S, Tornillo L, Terracciano LM.

Angiogenesis. 2014 Jul;17(3):519-27. doi: 10.1007/s10456-013-9396-z. Epub 2013 Oct 11.

PMID:
24114200
41.

Estrogen receptor β expression and androgen receptor phosphorylation correlate with a poor clinical outcome in hormone-naive prostate cancer and are elevated in castration-resistant disease.

Zellweger T, Stürm S, Rey S, Zlobec I, Gsponer JR, Rentsch CA, Terracciano LM, Bachmann A, Bubendorf L, Ruiz C.

Endocr Relat Cancer. 2013 May 21;20(3):403-13. doi: 10.1530/ERC-12-0402. Print 2013 Jun.

PMID:
23580588
42.

Venlafaxine-induced cholestatic hepatitis: case report and review of literature.

Stadlmann S, Portmann S, Tschopp S, Terracciano LM.

Am J Surg Pathol. 2012 Nov;36(11):1724-8. doi: 10.1097/PAS.0b013e31826af296. Review.

PMID:
23073329
43.

Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.

Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC.

Clin Cancer Res. 2012 Sep 1;18(17):4570-9. doi: 10.1158/1078-0432.CCR-12-0550. Epub 2012 Aug 23.

44.

Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis.

Ruiz C, Martins JR, Rudin F, Schneider S, Dietsche T, Fischer CA, Tornillo L, Terracciano LM, Schreiber R, Bubendorf L, Kunzelmann K.

PLoS One. 2012;7(8):e43265. doi: 10.1371/journal.pone.0043265. Epub 2012 Aug 17.

45.

The clinical impact of p16 status in fine-needle aspirates of cervical lymph node metastasis of head and neck squamous cell carcinomas.

Jakscha J, Zlobec I, Storck C, Obermann EC, Tornillo L, Terracciano LM, Fischer CA.

Eur Arch Otorhinolaryngol. 2013 Feb;270(2):661-7. doi: 10.1007/s00405-012-2039-y. Epub 2012 May 16.

PMID:
22588195
46.

High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth.

Ruiz C, Oeggerli M, Germann M, Gluderer S, Stocker H, Andreozzi M, Thalmann GN, Cecchini MG, Zellweger T, Stürm S, Koivisto PA, Helin HJ, Gelmann EP, Glass AG, Gasser TC, Terracciano LM, Bachmann A, Wyler S, Bubendorf L, Rentsch CA.

Prostate. 2012 Nov;72(15):1678-87. doi: 10.1002/pros.22521. Epub 2012 Apr 2.

PMID:
22473923
47.

Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater.

Piscuoglio S, Lehmann FS, Zlobec I, Tornillo L, Dietmaier W, Hartmann A, Wünsch PH, Sessa F, Rümmele P, Baumhoer D, Terracciano LM.

J Clin Pathol. 2012 Feb;65(2):140-5. doi: 10.1136/jclinpath-2011-200043. Epub 2011 Nov 30.

PMID:
22130902
48.

Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer.

Friedbichler K, Themanns M, Mueller KM, Schlederer M, Kornfeld JW, Terracciano LM, Kozlov AV, Haindl S, Kenner L, Kolbe T, Mueller M, Snibson KJ, Heim MH, Moriggl R.

Hepatology. 2012 Mar;55(3):941-52. doi: 10.1002/hep.24765. Epub 2012 Jan 13.

PMID:
22031092
49.

Intratumoral budding as a potential parameter of tumor progression in mismatch repair-proficient and mismatch repair-deficient colorectal cancer patients.

Lugli A, Vlajnic T, Giger O, Karamitopoulou E, Patsouris ES, Peros G, Terracciano LM, Zlobec I.

Hum Pathol. 2011 Dec;42(12):1833-40. doi: 10.1016/j.humpath.2011.02.010. Epub 2011 Jun 12.

PMID:
21664647
50.

Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.

Karamitopoulou E, Zlobec I, Panayiotides I, Patsouris ES, Peros G, Rallis G, Lapas C, Karakitsos P, Terracciano LM, Lugli A.

Hum Pathol. 2011 Dec;42(12):1888-96. doi: 10.1016/j.humpath.2010.06.020. Epub 2011 Jun 12.

PMID:
21664646

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