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Biochem Soc Trans. 2006 Apr;34(Pt 2):304-8.

Green oxidations with laccase-mediator systems.

Author information

1
Process R&D, AstraZeneca, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK. andrew.wells@astrazeneca.com

Abstract

Laccases are oxidase enzymes produced by 'white rot' fungi as part of a complex armoury of redox enzymes used to break down lignin--part of the carbon cycle of nature. Laccases alone or in combination with redox co-catalysts have been shown to oxidize xenobiotic compounds under conditions that can be described as 'green'. This paper describes some novel oxidations using the laccase-mediator method and some current limitations to the use of this technology.

PMID:
16545100
DOI:
10.1042/BST20060304
[Indexed for MEDLINE]

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