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Items: 1 to 50 of 378

1.

Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T Cells.

Shirley JL, Keeler GD, Sherman A, Zolotukhin I, Markusic DM, Hoffman BE, Morel LM, Wallet MA, Terhorst C, Herzog RW.

Mol Ther. 2019 Nov 15. pii: S1525-0016(19)30507-6. doi: 10.1016/j.ymthe.2019.11.011. [Epub ahead of print]

PMID:
31780366
2.

Evolutionary responses to global change in species-rich communities.

Lau JA, terHorst CP.

Ann N Y Acad Sci. 2019 Aug 22. doi: 10.1111/nyas.14221. [Epub ahead of print] Review.

PMID:
31441072
3.

SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer.

Yigit B, Wang N, Ten Hacken E, Chen SS, Bhan AK, Suarez-Fueyo A, Katsuyama E, Tsokos GC, Chiorazzi N, Wu CJ, Burger JA, Herzog RW, Engel P, Terhorst C.

Cancer Immunol Res. 2019 Sep;7(9):1485-1496. doi: 10.1158/2326-6066.CIR-18-0664. Epub 2019 Jul 17.

PMID:
31315913
4.

TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer.

Butterfield JSS, Biswas M, Shirley JL, Kumar SRP, Sherman A, Terhorst C, Ling C, Herzog RW.

Hum Gene Ther Methods. 2019 Jun;30(3):81-92. doi: 10.1089/hgtb.2019.013.

PMID:
31140323
5.

Illegal Trade of Wild-Captured Lemur catta within Madagascar.

LaFleur M, Clarke TA, Reuter KE, Schaefer MS, terHorst C.

Folia Primatol (Basel). 2019;90(4):199-214. doi: 10.1159/000496970. Epub 2019 May 8.

6.

The Checkpoint Regulator SLAMF3 Preferentially Prevents Expansion of Auto-Reactive B Cells Generated by Graft-vs.-Host Disease.

Wang N, Yigit B, van der Poel CE, Cuenca M, Carroll MC, Herzog RW, Engel P, Terhorst C.

Front Immunol. 2019 Apr 17;10:831. doi: 10.3389/fimmu.2019.00831. eCollection 2019.

7.

Genetic variation in Breviolum antillogorgium, a coral reef symbiont, in response to temperature and nutrients.

Bayliss SLJ, Scott ZR, Coffroth MA, terHorst CP.

Ecol Evol. 2019 Feb 7;9(5):2803-2813. doi: 10.1002/ece3.4959. eCollection 2019 Mar.

8.

Reprogrammed CD4+ T Cells That Express FoxP3+ Control Inhibitory Antibody Formation in Hemophilia A Mice.

Herzog RW, Kuteyeva V, Saboungi R, Terhorst C, Biswas M.

Front Immunol. 2019 Feb 20;10:274. doi: 10.3389/fimmu.2019.00274. eCollection 2019.

9.

β-Barrel outer membrane proteins suppress mTORC2 activation and induce autophagic responses.

Chaudhary A, Kamischke C, Leite M, Altura MA, Kinman L, Kulasekara H, Blanc MP, Wang G, Terhorst C, Miller SI.

Sci Signal. 2018 Nov 27;11(558). pii: eaat7493. doi: 10.1126/scisignal.aat7493.

PMID:
30482849
10.

SLAMF6 in health and disease: Implications for therapeutic targeting.

Yigit B, Wang N, Herzog RW, Terhorst C.

Clin Immunol. 2019 Jul;204:3-13. doi: 10.1016/j.clim.2018.10.013. Epub 2018 Oct 23. Review. No abstract available.

PMID:
30366106
11.

Pick your trade-offs wisely: Predator-prey eco-evo dynamics are qualitatively different under different trade-offs.

Fleischer SR, terHorst CP, Li J.

J Theor Biol. 2018 Nov 7;456:201-212. doi: 10.1016/j.jtbi.2018.08.013. Epub 2018 Aug 9.

PMID:
30099079
12.

2B4 Mediates Inhibition of CD8+ T Cell Responses via Attenuation of Glycolysis and Cell Division.

Laurie SJ, Liu D, Wagener ME, Stark PC, Terhorst C, Ford ML.

J Immunol. 2018 Sep 1;201(5):1536-1548. doi: 10.4049/jimmunol.1701240. Epub 2018 Jul 16.

13.

Genetic variation in mutualistic and antagonistic interactions in an invasive legume.

terHorst CP, Wirth C, Lau JA.

Oecologia. 2018 Sep;188(1):159-171. doi: 10.1007/s00442-018-4211-6. Epub 2018 Jun 25.

PMID:
29943143
14.

Evolution of increased Medicaco polymorpha size during invasion does not result in increased competitive ability.

Getman-Pickering ZL, terHorst CP, Magnoli SM, Lau JA.

Oecologia. 2018 Sep;188(1):203-212. doi: 10.1007/s00442-018-4168-5. Epub 2018 May 25.

PMID:
29802448
15.

Gene Therapy With Regulatory T Cells: A Beneficial Alliance.

Biswas M, Kumar SRP, Terhorst C, Herzog RW.

Front Immunol. 2018 Mar 19;9:554. doi: 10.3389/fimmu.2018.00554. eCollection 2018. Review.

16.

SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages.

Yurchenko M, Skjesol A, Ryan L, Richard GM, Kandasamy RK, Wang N, Terhorst C, Husebye H, Espevik T.

J Cell Biol. 2018 Apr 2;217(4):1411-1429. doi: 10.1083/jcb.201707027. Epub 2018 Feb 12.

17.

The future of ecology is collaborative, inclusive and deconstructs biases.

Ramirez KS, Berhe AA, Burt J, Gil-Romera G, Johnson RF, Koltz AM, Lacher I, McGlynn T, Nielsen KJ, Schmidt R, Simonis JL, terHorst CP, Tuff K.

Nat Ecol Evol. 2018 Feb;2(2):200. doi: 10.1038/s41559-017-0445-7. No abstract available.

PMID:
29242579
18.

Ly9 (SLAMF3) receptor differentially regulates iNKT cell development and activation in mice.

Cuenca M, Puñet-Ortiz J, Ruart M, Terhorst C, Engel P.

Eur J Immunol. 2018 Jan;48(1):99-105. doi: 10.1002/eji.201746925. Epub 2017 Nov 7.

19.

Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer.

Herzog RW, Cooper M, Perrin GQ, Biswas M, Martino AT, Morel L, Terhorst C, Hoffman BE.

Cell Immunol. 2019 Aug;342:103682. doi: 10.1016/j.cellimm.2017.07.012. Epub 2017 Aug 1.

PMID:
28888664
20.

Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462-469.

Sayos J, Wu C, Morra M, Wang N, Zhang X, Allen D, van Schaik S, Notarangelo L, Geha R, Roncarolo MG, Oettgen H, De Vries JE, Aversa G, Terhorst C.

J Immunol. 2017 Sep 1;199(5):1534-1541. No abstract available.

21.

Cutting Edge: 2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis.

Chen CW, Mittal R, Klingensmith NJ, Burd EM, Terhorst C, Martin GS, Coopersmith CM, Ford ML.

J Immunol. 2017 Sep 15;199(6):1961-1966. doi: 10.4049/jimmunol.1700375. Epub 2017 Aug 2.

22.

Inhibition of reactive oxygen species limits expansion of chronic lymphocytic leukemia cells.

Yigit B, Wang N, Chen SS, Chiorazzi N, Terhorst C.

Leukemia. 2017 Oct;31(10):2273-2276. doi: 10.1038/leu.2017.241. Epub 2017 Jul 28. No abstract available.

PMID:
28751772
23.

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells.

Rogers GL, Shirley JL, Zolotukhin I, Kumar SRP, Sherman A, Perrin GQ, Hoffman BE, Srivastava A, Basner-Tschakarjan E, Wallet MA, Terhorst C, Biswas M, Herzog RW.

Blood. 2017 Jun 15;129(24):3184-3195. doi: 10.1182/blood-2016-11-751040. Epub 2017 May 3.

24.

The Balance between CD8+ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.

Kumar SRP, Hoffman BE, Terhorst C, de Jong YP, Herzog RW.

Mol Ther. 2017 Apr 5;25(4):880-891. doi: 10.1016/j.ymthe.2017.02.014. Epub 2017 Mar 9.

25.

Design and Synthesis of Nanofibers of Self-assembled de novo Glycoconjugates towards Mucosal Lining Restoration and Anti-Inflammatory Drug Delivery.

Zhou J, O'Keeffe M, Liao G, Zhao F, Terhorst C, Xu B.

Tetrahedron. 2016 Oct 6;72(40):6078-6083. doi: 10.1016/j.tet.2016.07.057. Epub 2016 Jul 26.

26.

Testing genotypic variation of an invasive plant species in response to soil disturbance and herbivory.

Bayliss SL, terHorst CP, Lau JA.

Oecologia. 2017 Apr;183(4):1135-1141. doi: 10.1007/s00442-017-3820-9. Epub 2017 Jan 28.

PMID:
28132104
27.

Quantifying nonadditive selection caused by indirect ecological effects: Reply.

terHorst CP, Lau JA, Conner JK.

Ecology. 2017 Apr;98(4):1171-1175. doi: 10.1002/ecy.1744. Epub 2017 Mar 20. No abstract available.

PMID:
28122136
28.

Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transfer.

Perrin GQ, Zolotukhin I, Sherman A, Biswas M, de Jong YP, Terhorst C, Davidoff AM, Herzog RW.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16083. eCollection 2016.

29.

Slamf6 negatively regulates autoimmunity.

Wang N, Keszei M, Halibozek P, Yigit B, Engel P, Terhorst C.

Clin Immunol. 2016 Dec;173:19-26. doi: 10.1016/j.clim.2016.06.009. Epub 2016 Jun 29.

30.

A shift from exploitation to interference competition with increasing density affects population and community dynamics.

Holdridge EM, Cuellar-Gempeler C, terHorst CP.

Ecol Evol. 2016 Jul 1;6(15):5333-41. doi: 10.1002/ece3.2284. eCollection 2016 Aug.

31.

IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.

Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Tessier PA, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS.

J Exp Med. 2016 Sep 19;213(10):2147-66. doi: 10.1084/jem.20150376. Epub 2016 Aug 22.

32.

Human Diversity in a Cell Surface Receptor that Inhibits Autophagy.

Chaudhary A, Leite M, Kulasekara BR, Altura MA, Ogahara C, Weiss E, Fu W, Blanc MP, O'Keeffe M, Terhorst C, Akey JM, Miller SI.

Curr Biol. 2016 Jul 25;26(14):1791-801. doi: 10.1016/j.cub.2016.05.003. Epub 2016 Jun 23.

33.

Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production.

Karampetsou MP, Comte D, Kis-Toth K, Terhorst C, Kyttaris VC, Tsokos GC.

J Immunol. 2016 Jun 15;196(12):4915-24. doi: 10.4049/jimmunol.1501523. Epub 2016 May 11.

34.

Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.

Wang J, Mizui M, Zeng LF, Bronson R, Finnell M, Terhorst C, Kyttaris VC, Tsokos GC, Zhang ZY, Kontaridis MI.

J Clin Invest. 2016 Jun 1;126(6):2077-92. doi: 10.1172/JCI87037. Epub 2016 May 16.

35.

A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells.

Yigit B, Halibozek PJ, Chen SS, O'Keeffe MS, Arnason J, Avigan D, Gattei V, Bhan A, Cen O, Longnecker R, Chiorazzi N, Wang N, Engel P, Terhorst C.

Oncotarget. 2016 May 3;7(18):26346-60. doi: 10.18632/oncotarget.8378.

36.

Responses to Microbial Challenges by SLAMF Receptors.

van Driel BJ, Liao G, Engel P, Terhorst C.

Front Immunol. 2016 Jan 20;7:4. doi: 10.3389/fimmu.2016.00004. eCollection 2016. Review.

37.

Roles of CD48 in regulating immunity and tolerance.

McArdel SL, Terhorst C, Sharpe AH.

Clin Immunol. 2016 Mar;164:10-20. doi: 10.1016/j.clim.2016.01.008. Epub 2016 Jan 18. Review.

38.

Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses.

Cuenca M, Romero X, Sintes J, Terhorst C, Engel P.

J Immunol. 2016 Jan 15;196(2):726-37. doi: 10.4049/jimmunol.1501266. Epub 2015 Dec 14.

39.

SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response.

Bologna C, Buonincontri R, Serra S, Vaisitti T, Audrito V, Brusa D, Pagnani A, Coscia M, D'Arena G, Mereu E, Piva R, Furman RR, Rossi D, Gaidano G, Terhorst C, Deaglio S.

J Clin Invest. 2016 Jan;126(1):181-94. doi: 10.1172/JCI83013. Epub 2015 Nov 30.

40.

Quantifying nonadditive selection caused by indirect ecological effects.

TerHorst CP, Lau JA, Cooper IA, Keller KR, La Rosa RJ, Royer AM, Schultheis EH, Suwa T, Conner JK.

Ecology. 2015 Sep;96(9):2360-9.

PMID:
26594694
41.

In vivo induction of regulatory T cells for immune tolerance in hemophilia.

Wang X, Terhorst C, Herzog RW.

Cell Immunol. 2016 Mar;301:18-29. doi: 10.1016/j.cellimm.2015.10.001. Epub 2015 Oct 9. Review.

42.

Signaling Lymphocytic Activation Molecule Family Receptor Homologs in New World Monkey Cytomegaloviruses.

Pérez-Carmona N, Farré D, Martínez-Vicente P, Terhorst C, Engel P, Angulo A.

J Virol. 2015 Nov;89(22):11323-36. doi: 10.1128/JVI.01296-15. Epub 2015 Sep 2.

43.

Selective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus.

Kis-Toth K, Comte D, Karampetsou MP, Kyttaris VC, Kannan L, Terhorst C, Tsokos GC.

Arthritis Rheumatol. 2016 Jan;68(1):164-73. doi: 10.1002/art.39410.

44.

Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.

Thiele M, Kerschbaumer RJ, Tam FW, Völkel D, Douillard P, Schinagl A, Kühnel H, Smith J, McDaid JP, Bhangal G, Yu MC, Pusey CD, Cook HT, Kovarik J, Magelky E, Bhan A, Rieger M, Mudde GC, Ehrlich H, Jilma B, Tilg H, Moschen A, Terhorst C, Scheiflinger F.

J Immunol. 2015 Sep 1;195(5):2343-52. doi: 10.4049/jimmunol.1500572. Epub 2015 Jul 24.

45.

Treg: tolerance vs immunity.

Biswas M, Terhorst C, Herzog RW.

Oncotarget. 2015 Aug 21;6(24):19956-7. No abstract available.

46.

The cell surface receptor Slamf6 modulates innate immune responses during Citrobacter rodentium-induced colitis.

van Driel B, Wang G, Liao G, Halibozek PJ, Keszei M, O'Keeffe MS, Bhan AK, Wang N, Terhorst C.

Int Immunol. 2015 Sep;27(9):447-57. doi: 10.1093/intimm/dxv029. Epub 2015 May 8.

47.

Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors.

Wang N, Halibozek PJ, Yigit B, Zhao H, O'Keeffe MS, Sage P, Sharpe A, Terhorst C.

Front Immunol. 2015 Apr 14;6:158. doi: 10.3389/fimmu.2015.00158. eCollection 2015.

48.

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg.

Biswas M, Sarkar D, Kumar SR, Nayak S, Rogers GL, Markusic DM, Liao G, Terhorst C, Herzog RW.

Blood. 2015 May 7;125(19):2937-47. doi: 10.1182/blood-2014-09-599266. Epub 2015 Apr 1.

49.

Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.

Wang G, van Driel BJ, Liao G, O'Keeffe MS, Halibozek PJ, Flipse J, Yigit B, Azcutia V, Luscinskas FW, Wang N, Terhorst C.

PLoS One. 2015 Mar 23;10(3):e0121968. doi: 10.1371/journal.pone.0121968. eCollection 2015.

50.

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells.

Wang X, Su J, Sherman A, Rogers GL, Liao G, Hoffman BE, Leong KW, Terhorst C, Daniell H, Herzog RW.

Blood. 2015 Apr 9;125(15):2418-27. doi: 10.1182/blood-2014-08-597070. Epub 2015 Feb 19.

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