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Working with patients to improve care.

Kiran T, Tepper J, Gavin F.

CMAJ. 2020 Feb 10;192(6):E125-E127. doi: 10.1503/cmaj.190439. No abstract available.


Novel Methods for the Assessment of Safety Pharmacology and Toxicology Parameters in Anesthetized and Ventilated Dogs Receiving Inhaled Drugs.

Bujold K, Pfeiffer J, Authier S, Malcolmson R, Fink J, Tepper J.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.151. Epub 2019 Oct 17. No abstract available.


Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204).

Chakravarthy AB, Zhao F, Meropol NJ, Flynn PJ, Wagner LI, Sloan J, Diasio RB, Mitchell EP, Catalano P, Giantonio BJ, Catalano RB, Haller DG, Awan RA, Mulcahy MF, O'Brien TE, Santala R, Cripps C, Weis JR, Atkins JN, Leichman CG, Petrelli NJ, Sinicrope FA, Brierley JD, Tepper JE, O'Dwyer PJ, Sigurdson ER, Hamilton SR, Cella D, Benson AB 3rd.

Oncologist. 2019 Dec 18. pii: theoncologist.2019-0437. doi: 10.1634/theoncologist.2019-0437. [Epub ahead of print]


How do emergency departments and emergency leaders catalyze positive change through quality improvement collaborations?

Chartier LB, Mondoux SE, Stang AS, Dukelow AM, Dowling SK, Kwok ESH, Trivedi SV, Tepper J, Lang E.

CJEM. 2019 Jul;21(4):542-549. doi: 10.1017/cem.2019.25.


Update on Prenatal Laboratory Screening: Joint Commission Required Elements.

Tepper JL, Puopolo KM.

Neoreviews. 2019 Oct;20(10):e584-e591. doi: 10.1542/neo.20-10-e584.


Neuropilin 2 Signaling Mediates Corticostriatal Transmission, Spine Maintenance, and Goal-Directed Learning in Mice.

Assous M, Martinez E, Eisenberg C, Shah F, Kosc A, Varghese K, Espinoza D, Bhimani S, Tepper JM, Shiflett MW, Tran TS.

J Neurosci. 2019 Nov 6;39(45):8845-8859. doi: 10.1523/JNEUROSCI.1006-19.2019. Epub 2019 Sep 20.


Cortical and thalamic inputs exert cell type-specific feedforward inhibition on striatal GABAergic interneurons.

Assous M, Tepper JM.

J Neurosci Res. 2019 Dec;97(12):1491-1502. doi: 10.1002/jnr.24444. Epub 2019 May 17.


Novel methods for the assessment of safety pharmacology and toxicology parameters in anesthetized and ventilated dogs receiving inhaled drugs.

Bujold K, Pfeiffer J, Fink J, Malcolmson R, Authier S, Tepper J.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106578. doi: 10.1016/j.vascn.2019.04.004. Epub 2019 May 9.


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018 Jun;2(6):443-452. doi: 10.1038/s41551-018-0231-0. Epub 2018 Apr 23.


Opposing Influence of Sensory and Motor Cortical Input on Striatal Circuitry and Choice Behavior.

Lee CR, Yonk AJ, Wiskerke J, Paradiso KG, Tepper JM, Margolis DJ.

Curr Biol. 2019 Apr 22;29(8):1313-1323.e5. doi: 10.1016/j.cub.2019.03.028. Epub 2019 Apr 11.


Pedunculopontine Glutamatergic Neurons Provide a Novel Source of Feedforward Inhibition in the Striatum by Selectively Targeting Interneurons.

Assous M, Dautan D, Tepper JM, Mena-Segovia J.

J Neurosci. 2019 Jun 12;39(24):4727-4737. doi: 10.1523/JNEUROSCI.2913-18.2019. Epub 2019 Apr 5.


Loss of striatal tyrosine-hydroxylase interneurons impairs instrumental goal-directed behavior.

Kaminer J, Espinoza D, Bhimani S, Tepper JM, Koos T, Shiflett MW.

Eur J Neurosci. 2019 Aug;50(4):2653-2662. doi: 10.1111/ejn.14412. Epub 2019 May 2.


Azithromycin vs erythromycin for the management of preterm premature rupture of membranes.

Navathe R, Schoen CN, Heidari P, Bachilova S, Ward A, Tepper J, Visintainer P, Hoffman MK, Smith S, Berghella V, Roman A.

Am J Obstet Gynecol. 2019 Aug;221(2):144.e1-144.e8. doi: 10.1016/j.ajog.2019.03.009. Epub 2019 Mar 20.


Phase I/II trial of nano-camptothecin CRLX101 with capecitabine and radiotherapy as neoadjuvant treatment for locally advanced rectal cancer.

Sanoff HK, Moon DH, Moore DT, Boles J, Bui C, Blackstock W, O'Neil BH, Subramaniam S, McRee AJ, Carlson C, Lee MS, Tepper JE, Wang AZ.

Nanomedicine. 2019 Jun;18:189-195. doi: 10.1016/j.nano.2019.02.021. Epub 2019 Mar 8.


Klein tunnelling and Hartman effect in graphene junctions with proximity exchange field.

Tepper J, Barnaś J.

J Phys Condens Matter. 2019 Jun 5;31(22):225302. doi: 10.1088/1361-648X/ab0b20. Epub 2019 Feb 27.


p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.

Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G.

Cancer Cell. 2019 Feb 11;35(2):204-220.e9. doi: 10.1016/j.ccell.2019.01.006.


Inappropriateness of health care in Canada: a systematic review protocol.

Squires JE, Graham ID, Grinspun D, Lavis J, Légaré F, Bell R, Bornstein S, Brien SE, Dobrow M, Greenough M, Estabrooks CA, Hillmer M, Horsley T, Katz A, Krause C, Levinson W, Levy A, Mancuso M, Maybee A, Morgan S, Penno LN, Neuner A, Rader T, Roberts J, Teare G, Tepper J, Vandyk A, Widmeyer D, Wilson M, Grimshaw JM.

Syst Rev. 2019 Feb 11;8(1):50. doi: 10.1186/s13643-019-0948-1.


A retrospective cohort study of fetal assessment following preterm premature rupture of membranes.

Tepper J, Corelli K, Navathe R, Smith S, Baxter JK.

Int J Gynaecol Obstet. 2019 Apr;145(1):83-90. doi: 10.1002/ijgo.12767. Epub 2019 Feb 19.


Mandibular width as a novel anthropometric measure for assessing obstructive sleep apnea risk.

Maresky HS, Klar MM, Tepper J, Gavriel H, Ziv Baran T, Shapiro CM, Tal S.

Medicine (Baltimore). 2019 Jan;98(4):e14040. doi: 10.1097/MD.0000000000014040.


Physician Characteristics Associated With Ordering 4 Low-Value Screening Tests in Primary Care.

Bouck Z, Ferguson J, Ivers NM, Kerr EA, Shojania KG, Kim M, Cram P, Pendrith C, Mecredy GC, Glazier RH, Tepper J, Austin PC, Martin D, Levinson W, Bhatia RS.

JAMA Netw Open. 2018 Oct 5;1(6):e183506. doi: 10.1001/jamanetworkopen.2018.3506.


Heterogeneity and Diversity of Striatal GABAergic Interneurons: Update 2018.

Tepper JM, Koós T, Ibanez-Sandoval O, Tecuapetla F, Faust TW, Assous M.

Front Neuroanat. 2018 Nov 8;12:91. doi: 10.3389/fnana.2018.00091. eCollection 2018.


"Wisest Is He Who Knows What He Does Not Know."

Marks LB, Tepper JE.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):687-690. doi: 10.1016/j.ijrobp.2018.01.009. Epub 2018 Oct 18. No abstract available.


Frequency and Associations of Prescription Nonsteroidal Anti-inflammatory Drug Use Among Patients With a Musculoskeletal Disorder and Hypertension, Heart Failure, or Chronic Kidney Disease.

Bouck Z, Mecredy GC, Ivers NM, Barua M, Martin D, Austin PC, Tepper J, Bhatia RS.

JAMA Intern Med. 2018 Nov 1;178(11):1516-1525. doi: 10.1001/jamainternmed.2018.4273.


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018;2:443-452. Epub 2018 Apr 23.


Improving the quality of health care in Canada.

Dhalla IA, Tepper J.

CMAJ. 2018 Oct 1;190(39):E1162-E1167. doi: 10.1503/cmaj.171045. No abstract available.


Routine use of chest x-ray for low-risk patients undergoing a periodic health examination: a retrospective cohort study.

Bouck Z, Mecredy G, Ivers NM, Pendrith C, Fine B, Martin D, Glazier RH, Tepper J, Levinson W, Bhatia RS.

CMAJ Open. 2018 Aug 13;6(3):E322-E329. doi: 10.9778/cmajo.20170138. Print 2018 Jul-Sep.


Identification and Characterization of a Novel Spontaneously Active Bursty GABAergic Interneuron in the Mouse Striatum.

Assous M, Faust TW, Assini R, Shah F, Sidibe Y, Tepper JM.

J Neurosci. 2018 Jun 20;38(25):5688-5699. doi: 10.1523/JNEUROSCI.3354-17.2018. Epub 2018 May 22.


Measuring situation awareness in medical education objective structured clinical examination guides.

Frere M, Tepper J, Fischer M, Kennedy K, Kropmans T.

Educ Health (Abingdon). 2017 Sep-Dec;30(3):193-197. doi: 10.4103/efh.EfH_306_16.


Advancing Primary Care Through Alternative Payment Models: Lessons from the United States & Canada.

Bazemore A, Phillips RL Jr, Glazier R, Tepper J.

J Am Board Fam Med. 2018 May-Jun;31(3):322-327. doi: 10.3122/jabfm.2018.03.170297.


Bridging Hospital and Community Care for Homeless Adults with Mental Health Needs: Outcomes of a Brief Interdisciplinary Intervention.

Stergiopoulos V, Gozdzik A, Nisenbaum R, Durbin J, Hwang SW, O'Campo P, Tepper J, Wasylenki D.

Can J Psychiatry. 2018 Nov;63(11):774-784. doi: 10.1177/0706743718772539. Epub 2018 May 1.


Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches-Meeting Viewpoint.

Ahmed MM, Coleman CN, Mendonca M, Bentzen S, Vikram B, Seltzer SM, Goodhead D, Obcemea C, Mohan R, Prise KM, Capala J, Citrin D, Kao G, Aryankalayil M, Eke I, Buchsbaum JC, Prasanna PGS, Liu FF, Le QT, Teicher B, Kirsch DG, Smart D, Tepper J, Formenti S, Haas-Kogan D, Raben D, Mitchell J.

Cancer Res. 2018 May 1;78(9):2166-2170. doi: 10.1158/0008-5472.CAN-17-3760. Epub 2018 Apr 23. No abstract available.


Mature results of a prospective study of deintensified chemoradiotherapy for low-risk human papillomavirus-associated oropharyngeal squamous cell carcinoma.

Chera BS, Amdur RJ, Tepper JE, Tan X, Weiss J, Grilley-Olson JE, Hayes DN, Zanation A, Hackman TG, Patel S, Sheets N, Weissler MC, Mendenhall WM.

Cancer. 2018 Jun 1;124(11):2347-2354. doi: 10.1002/cncr.31338. Epub 2018 Mar 26.


Multivalent Binding and Biomimetic Cell Rolling Improves the Sensitivity and Specificity of Circulating Tumor Cell Capture.

Myung JH, Eblan MJ, Caster JM, Park SJ, Poellmann MJ, Wang K, Tam KA, Miller SM, Shen C, Chen RC, Zhang T, Tepper JE, Chera BS, Wang AZ, Hong S.

Clin Cancer Res. 2018 Jun 1;24(11):2539-2547. doi: 10.1158/1078-0432.CCR-17-3078. Epub 2018 Mar 15.


Excitatory extrinsic afferents to striatal interneurons and interactions with striatal microcircuitry.

Assous M, Tepper JM.

Eur J Neurosci. 2019 Mar;49(5):593-603. doi: 10.1111/ejn.13881. Epub 2018 Mar 25. Review.


A prospective study of the safety and efficacy of liver stereotactic body radiotherapy in patients with and without prior liver-directed therapy.

Moon DH, Wang AZ, Tepper JE.

Radiother Oncol. 2018 Mar;126(3):527-533. doi: 10.1016/j.radonc.2018.01.004. Epub 2018 Jan 30.


Toxicology Evaluation of Drugs Administered via Uncommon Routes: Intranasal, Intraocular, Intrathecal/Intraspinal, and Intra-Articular.

Emami A, Tepper J, Short B, Yaksh TL, Bendele AM, Ramani T, Cisternas AF, Chang JH, Mellon RD.

Int J Toxicol. 2018 Jan/Feb;37(1):4-27. doi: 10.1177/1091581817741840. Epub 2017 Dec 21.


Ultrafast laser inscription in ZBLAN integrated optics chips for mid-IR beam combination in astronomical interferometry.

Tepper J, Labadie L, Gross S, Arriola A, Minardi S, Diener R, Withford MJ.

Opt Express. 2017 Aug 21;25(17):20642-20653. doi: 10.1364/OE.25.020642.


Towards 3D-photonic, multi-telescope beam combiners for mid-infrared astrointerferometry.

Diener R, Tepper J, Labadie L, Pertsch T, Nolte S, Minardi S.

Opt Express. 2017 Aug 7;25(16):19262-19274. doi: 10.1364/OE.25.019262.


Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance).

Fuchs CS, Niedzwiecki D, Mamon HJ, Tepper JE, Ye X, Swanson RS, Enzinger PC, Haller DG, Dragovich T, Alberts SR, Bjarnason GA, Willett CG, Gunderson LL, Goldberg RM, Venook AP, Ilson D, O'Reilly E, Ciombor K, Berg DJ, Meyerhardt J, Mayer RJ.

J Clin Oncol. 2017 Nov 10;35(32):3671-3677. doi: 10.1200/JCO.2017.74.2130. Epub 2017 Oct 4.


Oncologist, cancer patient, oncologist.

Tepper JE.

Pract Radiat Oncol. 2018 Sep - Oct;8(5):295-296. doi: 10.1016/j.prro.2017.08.007. Epub 2017 Aug 31. No abstract available.


Defining Health Profession Regulators' Roles in the Canadian Healthcare System.

Tepper J, Ahmed H, Brown AD.

Healthc Pap. 2017;16(4):4-7.


Ethics in Clinical Care.

Tepper JE.

Int J Radiat Oncol Biol Phys. 2017 Oct 1;99(2):250-254. doi: 10.1016/j.ijrobp.2017.03.036. Epub 2017 Mar 29. No abstract available.


Electrocardiograms in Low-Risk Patients Undergoing an Annual Health Examination.

Bhatia RS, Bouck Z, Ivers NM, Mecredy G, Singh J, Pendrith C, Ko DT, Martin D, Wijeysundera HC, Tu JV, Wilson L, Wintemute K, Dorian P, Tepper J, Austin PC, Glazier RH, Levinson W.

JAMA Intern Med. 2017 Sep 1;177(9):1326-1333. doi: 10.1001/jamainternmed.2017.2649.


The Ketogenic Diet: A Solution to Ireland's Obesity Epidemic?

Tepper J, Frere M.

Ir Med J. 2017 Mar 10;110(3):526. No abstract available.


Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy.

Min Y, Roche KC, Tian S, Eblan MJ, McKinnon KP, Caster JM, Chai S, Herring LE, Zhang L, Zhang T, DeSimone JM, Tepper JE, Vincent BG, Serody JS, Wang AZ.

Nat Nanotechnol. 2017 Sep;12(9):877-882. doi: 10.1038/nnano.2017.113. Epub 2017 Jun 26.


Differential processing of thalamic information via distinct striatal interneuron circuits.

Assous M, Kaminer J, Shah F, Garg A, Koós T, Tepper JM.

Nat Commun. 2017 Jun 12;8:15860. doi: 10.1038/ncomms15860.



Koong AC, Tepper JE.

Semin Radiat Oncol. 2017 Jul;27(3):189. doi: 10.1016/j.semradonc.2017.03.005. Epub 2017 Mar 18. No abstract available.


Promoting continuity of care for homeless adults with unmet health needs: The role of brief interventions.

Lamanna D, Stergiopoulos V, Durbin J, O'Campo P, Poremski D, Tepper J.

Health Soc Care Community. 2018 Jan;26(1):56-64. doi: 10.1111/hsc.12461. Epub 2017 Jun 1.


Geriatric Assessment as a Predictor of Tolerance, Quality of Life, and Outcomes in Older Patients With Head and Neck Cancers and Lung Cancers Receiving Radiation Therapy.

VanderWalde NA, Deal AM, Comitz E, Stravers L, Muss H, Reeve BB, Basch E, Tepper J, Chera B.

Int J Radiat Oncol Biol Phys. 2017 Jul 15;98(4):850-857. doi: 10.1016/j.ijrobp.2016.11.048. Epub 2016 Dec 2.


Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

Genovese G, Carugo A, Tepper J, Robinson FS, Li L, Svelto M, Nezi L, Corti D, Minelli R, Pettazzoni P, Gutschner T, Wu CC, Seth S, Akdemir KC, Leo E, Amin S, Molin MD, Ying H, Kwong LN, Colla S, Takahashi K, Ghosh P, Giuliani V, Muller F, Dey P, Jiang S, Garvey J, Liu CG, Zhang J, Heffernan TP, Toniatti C, Fleming JB, Goggins MG, Wood LD, Sgambato A, Agaimy A, Maitra A, Roberts CW, Wang H, Viale A, DePinho RA, Draetta GF, Chin L.

Nature. 2017 Feb 16;542(7641):362-366. doi: 10.1038/nature21064. Epub 2017 Feb 8.


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