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Items: 1 to 50 of 174

1.

N-glucuronidation of perfluorooctanesulfonamide by human, rat, dog, and monkey liver microsomes and by expressed rat and human UDP-glucuronosyltransferases.

Xu L, Krenitsky DM, Seacat AM, Butenhoff JL, Tephly TR, Anders MW.

Drug Metab Dispos. 2006 Aug;34(8):1406-10. Epub 2006 May 23.

PMID:
16720684
2.

Opioids bind to the amino acids 84 to 118 of UDP-glucuronosyltransferase UGT2B7.

Coffman BL, Kearney WR, Goldsmith S, Knosp BM, Tephly TR.

Mol Pharmacol. 2003 Feb;63(2):283-8.

PMID:
12527799
3.

Inhibition and active sites of UDP-glucuronosyltransferases 2B7 and 1A1.

Rios GR, Tephly TR.

Drug Metab Dispos. 2002 Dec;30(12):1364-7.

PMID:
12433804
4.

Measurements of UDP- glucuronosyltransferase (UGT) activities.

Coffman BL, Rios GR, Tephly TR.

Curr Protoc Toxicol. 2002;Chapter 4:Unit4.3. doi: 10.1002/0471140856.tx0403s13.

PMID:
23045083
5.

Aspartame: review of safety.

Butchko HH, Stargel WW, Comer CP, Mayhew DA, Benninger C, Blackburn GL, de Sonneville LM, Geha RS, Hertelendy Z, Koestner A, Leon AS, Liepa GU, McMartin KE, Mendenhall CL, Munro IC, Novotny EJ, Renwick AG, Schiffman SS, Schomer DL, Shaywitz BA, Spiers PA, Tephly TR, Thomas JA, Trefz FK.

Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. Review.

PMID:
12180494
7.

UDP-glucuronosyltransferases.

King CD, Rios GR, Green MD, Tephly TR.

Curr Drug Metab. 2000 Sep;1(2):143-61. Review.

PMID:
11465080
8.

Analysis of opioid binding to UDP-glucuronosyltransferase 2B7 fusion proteins using nuclear magnetic resonance spectroscopy.

Coffman BL, Kearney WR, Green MD, Lowery RG, Tephly TR.

Mol Pharmacol. 2001 Jun;59(6):1464-9.

PMID:
11353807
9.

Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved.

Jude AR, Little JM, Czernik PJ, Tephly TR, Grant DF, Radominska-Pandya A.

Arch Biochem Biophys. 2001 May 15;389(2):176-86.

PMID:
11339806
10.
11.

3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7).

Barbier O, Turgeon D, Girard C, Green MD, Tephly TR, Hum DW, Bélanger A.

Drug Metab Dispos. 2000 May;28(5):497-502.

PMID:
10772627
12.

4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7.

Samokyszyn VM, Gall WE, Zawada G, Freyaldenhoven MA, Chen G, Mackenzie PI, Tephly TR, Radominska-Pandya A.

J Biol Chem. 2000 Mar 10;275(10):6908-14.

13.

Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7.

Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radominska-Pandya A.

J Steroid Biochem Mol Biol. 1999 Jul-Aug;70(1-3):101-8.

PMID:
10529008
14.
15.

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

Cheng Z, Radominska-Pandya A, Tephly TR.

Drug Metab Dispos. 1999 Oct;27(10):1165-70.

PMID:
10497143
16.

Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by rat UDP-glucuronosyltransferase 2B1.

Ren Q, Murphy SE, Dannenberg AJ, Park JY, Tephly TR, Lazarus P.

Drug Metab Dispos. 1999 Sep;27(9):1010-6.

PMID:
10460800
17.

Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.

Nowell SA, Massengill JS, Williams S, Radominska-Pandya A, Tephly TR, Cheng Z, Strassburg CP, Tukey RH, MacLeod SL, Lang NP, Kadlubar FF.

Carcinogenesis. 1999 Jun;20(6):1107-14.

PMID:
10357796
18.

Symposium overview: Characterization of xenobiotic metabolizing enzyme function using heterologous expression systems.

Townsend AJ, Kiningham KK, St Clair D, Tephly TR, Morrow CS, Guengerich FP.

Toxicol Sci. 1999 Apr;48(2):143-50.

PMID:
10353304
19.

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

King CD, Rios GR, Assouline JA, Tephly TR.

Arch Biochem Biophys. 1999 May 1;365(1):156-62.

PMID:
10222050
20.

Folate and folate-dependent enzymes associated with rat CNS development.

Martinasevic MK, Rios GR, Miller MW, Tephly TR.

Dev Neurosci. 1999;21(1):29-35.

PMID:
10077699
21.

Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.

Cheng Z, Rios GR, King CD, Coffman BL, Green MD, Mojarrabi B, Mackenzie PI, Tephly TR.

Toxicol Sci. 1998 Sep;45(1):52-7.

PMID:
9848110
22.

UDP-glucuronosyltransferases in human intestinal mucosa.

Radominska-Pandya A, Little JM, Pandya JT, Tephly TR, King CD, Barone GW, Raufman JP.

Biochim Biophys Acta. 1998 Nov 2;1394(2-3):199-208.

PMID:
9795217
23.

Immunohistochemical localization of UDP-glucuronosyltransferases in rat brain during early development.

Martinasevic MK, King CD, Rios GR, Tephly TR.

Drug Metab Dispos. 1998 Oct;26(10):1039-41.

PMID:
9763411
24.

Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins.

Green MD, Tephly TR.

Drug Metab Dispos. 1998 Sep;26(9):860-7. Review.

PMID:
9733664
25.

Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.

Cheng Z, Radominska-Pandya A, Tephly TR.

Arch Biochem Biophys. 1998 Aug 15;356(2):301-5.

PMID:
9705221
26.

Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.

Green MD, King CD, Mojarrabi B, Mackenzie PI, Tephly TR.

Drug Metab Dispos. 1998 Jun;26(6):507-12.

PMID:
9616184
28.

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Coffman BL, King CD, Rios GR, Tephly TR.

Drug Metab Dispos. 1998 Jan;26(1):73-7.

PMID:
9443856
29.
30.

Metabolism of endobiotics and xenobiotics by UDP-glucuronosyltransferase.

Tephly TR, Green MD, Coffman BL, King C, Cheng Z, Rios G.

Adv Pharmacol. 1998;42:343-6. No abstract available.

PMID:
9327911
31.

Folate and 10-formyltetrahydrofolate dehydrogenase (FDH) expression in the central nervous system of the mature rat.

Neymeyer V, Tephly TR, Miller MW.

Brain Res. 1997 Aug 22;766(1-2):195-204.

PMID:
9359603
32.

Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene.

Lévesque E, Beaulieu M, Green MD, Tephly TR, Bélanger A, Hum DW.

Pharmacogenetics. 1997 Aug;7(4):317-25.

PMID:
9295060
33.

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Bélanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, Lancet D, Louisot P, Magdalou J, Chowdhury JR, Ritter JK, Schachter H, Tephly TR, Tipton KF, Nebert DW.

Pharmacogenetics. 1997 Aug;7(4):255-69. Review.

PMID:
9295054
34.

Glucuronidation of retinoids by rat recombinant UDP: glucuronosyltransferase 1.1 (bilirubin UGT).

Radominska A, Little JM, Lehman PA, Samokyszyn V, Rios GR, King CD, Green MD, Tephly TR.

Drug Metab Dispos. 1997 Jul;25(7):889-92.

PMID:
9224784
35.

Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds.

King CD, Rios GR, Green MD, MacKenzie PI, Tephly TR.

Drug Metab Dispos. 1997 Feb;25(2):251-5.

PMID:
9029056
36.

Human UGT2B7 catalyzes morphine glucuronidation.

Coffman BL, Rios GR, King CD, Tephly TR.

Drug Metab Dispos. 1997 Jan;25(1):1-4.

PMID:
9010622
37.

Folate and 10-formyltetrahydrofolate dehydrogenase in human and rat retina: relation to methanol toxicity.

Martinasevic MK, Green MD, Baron J, Tephly TR.

Toxicol Appl Pharmacol. 1996 Dec;141(2):373-81.

PMID:
8975761
38.

The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1.

King CD, Green MD, Rios GR, Coffman BL, Owens IS, Bishop WP, Tephly TR.

Arch Biochem Biophys. 1996 Aug 1;332(1):92-100.

PMID:
8806713
39.

UDP glucuronosyltransferase in the cirrhotic rat liver.

Debinski HS, Mackenzie PI, Lee CS, Mashford ML, Danks JA, Tephly TR, Green M, Desmond PV.

J Gastroenterol Hepatol. 1996 Apr;11(4):373-9.

PMID:
8713705
40.
41.
42.

Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.

Green MD, Clarke DJ, Oturu EM, Styczynski PB, Jackson MR, Burchell B, Tephly TR.

Arch Biochem Biophys. 1995 Oct 1;322(2):460-8.

PMID:
7574722
44.

Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides.

Green MD, Bishop WP, Tephly TR.

Drug Metab Dispos. 1995 Mar;23(3):299-302.

PMID:
7628292
45.
46.

Studies on the glucuronidation of dopamine D-1 receptor antagonists, SCH 39166 and SCH 23390, by human liver microsomes.

Tephly TR, Coffman B, Styczynski P, Rios G, Charkowski DM, Vanrollins M, McQuade RD, Tedford CE.

Drug Metab Dispos. 1994 Sep-Oct;22(5):713-8.

PMID:
7835222
48.
49.

Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes.

Styczynski PB, Green MD, Coffman B, Tephly TR.

Drug Metab Dispos. 1992 Nov-Dec;20(6):896-901.

PMID:
1362943
50.

Formate metabolism in micropigs.

Tephly TR, Green MD, Gamble J.

Toxicol Appl Pharmacol. 1992 Sep;116(1):142-5.

PMID:
1529447

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