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Items: 39


Mutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1.

Ajeawung NF, Nguyen TTM, Lu L, Kucharski TJ, Rousseau J, Molidperee S, Atienza J, Gamache I, Jin W, Plon SE, Lee BH, Teodoro JG, Wang LL, Campeau PM.

Am J Hum Genet. 2019 Jul 10. pii: S0002-9297(19)30236-8. doi: 10.1016/j.ajhg.2019.06.011. [Epub ahead of print]


Reciprocal Regulation between 53BP1 and the Anaphase-Promoting Complex/Cyclosome Is Required for Genomic Stability during Mitotic Stress.

Kucharski TJ, Minshall PE, Moustafa-Kamal M, Turnell AS, Teodoro JG.

Cell Rep. 2017 Feb 21;18(8):1982-1995. doi: 10.1016/j.celrep.2017.01.080.


Activation of the Chicken Anemia Virus Apoptin Protein by Chk1/2 Phosphorylation Is Required for Apoptotic Activity and Efficient Viral Replication.

Kucharski TJ, Ng TF, Sharon DM, Navid-Azarbaijani P, Tavassoli M, Teodoro JG.

J Virol. 2016 Sep 29;90(20):9433-45. doi: 10.1128/JVI.00936-16. Print 2016 Oct 15.


Deletion of the putative tumor suppressor gene, G0s2, does not affect progression of Eμ-Myc driven lymphomas in mice.

Zagani R, Gamache I, Teodoro JG.

Leuk Res. 2016 Jan;40:100-2. doi: 10.1016/j.leukres.2015.11.011. Epub 2015 Dec 2.


Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells.

Zagani R, El-Assaad W, Gamache I, Teodoro JG.

Oncotarget. 2015 Sep 29;6(29):28282-95. doi: 10.18632/oncotarget.5061.


Targeting B16 tumors in vivo with peptide-conjugated gold nanoparticles.

Poon W, Zhang X, Bekah D, Teodoro JG, Nadeau JL.

Nanotechnology. 2015 Jul 17;26(28):285101. doi: 10.1088/0957-4484/26/28/285101. Epub 2015 Jun 26.


Intratumoral gold-doxorubicin is effective in treating melanoma in mice.

Zhang X, Teodoro JG, Nadeau JL.

Nanomedicine. 2015 Aug;11(6):1365-75. doi: 10.1016/j.nano.2015.04.001. Epub 2015 Apr 15.


Analysis by live imaging of effects of the adenovirus E4orf4 protein on passage through mitosis of H1299 tumor cells.

Sriskandarajah N, Blanchette P, Kucharski TJ, Teodoro JG, Branton PE.

J Virol. 2015 Apr;89(8):4685-9. doi: 10.1128/JVI.03437-14. Epub 2015 Feb 4.


Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice.

El-Assaad W, El-Kouhen K, Mohammad AH, Yang J, Morita M, Gamache I, Mamer O, Avizonis D, Hermance N, Kersten S, Tremblay ML, Kelliher MA, Teodoro JG.

Diabetologia. 2015 Jan;58(1):149-57. doi: 10.1007/s00125-014-3429-z. Epub 2014 Nov 9.


Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression.

Lu Y, Kucharski TJ, Gamache I, Blanchette P, Branton PE, Teodoro JG.

J Virol. 2014 Nov;88(22):13249-59. doi: 10.1128/JVI.00933-14. Epub 2014 Sep 10.


Multifaceted regulation of somatic cell reprogramming by mRNA translational control.

Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, Sonenberg N.

Cell Stem Cell. 2014 May 1;14(5):606-16. doi: 10.1016/j.stem.2014.02.005. Epub 2014 Mar 13.


Adenovirus E4orf4 protein-induced death of p53-/- H1299 human cancer cells follows a G1 arrest of both tetraploid and diploid cells due to a failure to initiate DNA synthesis.

Cabon L, Sriskandarajah N, Mui MZ, Teodoro JG, Blanchette P, Branton PE.

J Virol. 2013 Dec;87(24):13168-78. doi: 10.1128/JVI.01242-13. Epub 2013 Sep 25.


BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by βTrCP1.

Moustafa-Kamal M, Gamache I, Lu Y, Li S, Teodoro JG.

Cell Death Differ. 2013 Oct;20(10):1393-403. doi: 10.1038/cdd.2013.93. Epub 2013 Aug 2.


p53 inhibits angiogenesis by inducing the production of Arresten.

Assadian S, El-Assaad W, Wang XQ, Gannon PO, Barrès V, Latour M, Mes-Masson AM, Saad F, Sado Y, Dostie J, Teodoro JG.

Cancer Res. 2012 Mar 1;72(5):1270-9. doi: 10.1158/0008-5472.CAN-11-2348. Epub 2012 Jan 17.


DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin.

Kucharski TJ, Gamache I, Gjoerup O, Teodoro JG.

J Virol. 2011 Dec;85(23):12638-49. doi: 10.1128/JVI.05009-11. Epub 2011 Sep 21.


Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.

Smolders L, Teodoro JG.

Expert Opin Ther Targets. 2011 Jun;15(6):767-80. doi: 10.1517/14728222.2011.558008. Epub 2011 Mar 5. Review.


p53-dependent translational control of senescence and transformation via 4E-BPs.

Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, Shahbazian D, Livingstone M, Costa-Mattioli M, Teodoro JG, Sonenberg N.

Cancer Cell. 2009 Nov 6;16(5):439-46. doi: 10.1016/j.ccr.2009.09.025.


Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2.

Welch C, Santra MK, El-Assaad W, Zhu X, Huber WE, Keys RA, Teodoro JG, Green MR.

Cancer Res. 2009 Sep 1;69(17):6782-9. doi: 10.1158/0008-5472.CAN-09-0128. Epub 2009 Aug 25.


Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.

Cencic R, Carrier M, Galicia-Vázquez G, Bordeleau ME, Sukarieh R, Bourdeau A, Brem B, Teodoro JG, Greger H, Tremblay ML, Porco JA Jr, Pelletier J.

PLoS One. 2009;4(4):e5223. doi: 10.1371/journal.pone.0005223. Epub 2009 Apr 29.


Localization and importance of the adenovirus E4orf4 protein during lytic infection.

Miron MJ, Blanchette P, Groitl P, Dallaire F, Teodoro JG, Li S, Dobner T, Branton PE.

J Virol. 2009 Feb;83(4):1689-99. doi: 10.1128/JVI.01703-08. Epub 2008 Dec 10.


Regulation of collagen-derived antiangiogenic factors by p53.

Assadian S, Teodoro JG.

Expert Opin Biol Ther. 2008 Jul;8(7):941-50. doi: 10.1517/14712598.8.7.941 . Review.


Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome.

Teodoro JG, Evans SK, Green MR.

J Mol Med (Berl). 2007 Nov;85(11):1175-86. Epub 2007 Jun 23. Review.


p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase.

Teodoro JG, Parker AE, Zhu X, Green MR.

Science. 2006 Aug 18;313(5789):968-71.


The anaphase promoting complex: a critical target for viral proteins and anti-cancer drugs.

Heilman DW, Green MR, Teodoro JG.

Cell Cycle. 2005 Apr;4(4):560-3. Epub 2005 Apr 16. Review.


Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation.

Devireddy LR, Teodoro JG, Richard FA, Green MR.

Science. 2001 Aug 3;293(5531):829-34.


Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.

Querido E, Marcellus RC, Lai A, Charbonneau R, Teodoro JG, Ketner G, Branton PE.

J Virol. 1997 May;71(5):3788-98.


Regulation of apoptosis by viral gene products.

Teodoro JG, Branton PE.

J Virol. 1997 Mar;71(3):1739-46. Review. No abstract available.


Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein.

Marcellus RC, Teodoro JG, Charbonneau R, Shore GC, Branton PE.

Cell Growth Differ. 1996 Dec;7(12):1643-50.


Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis.

Marcellus RC, Teodoro JG, Wu T, Brough DE, Ketner G, Shore GC, Branton PE.

J Virol. 1996 Sep;70(9):6207-15.


Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase.

Boulakia CA, Chen G, Ng FW, Teodoro JG, Branton PE, Nicholson DW, Poirier GG, Shore GC.

Oncogene. 1996 Feb 1;12(3):529-35.


Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms.

Teodoro JG, Shore GC, Branton PE.

Oncogene. 1995 Aug 3;11(3):467-74.


Characterization of the 55K adenovirus type 5 E1B product and related proteins.

Takayesu D, Teodoro JG, Whalen SG, Branton PE.

J Gen Virol. 1994 Apr;75 ( Pt 4):789-98.


Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity.

Teodoro JG, Halliday T, Whalen SG, Takayesu D, Graham FL, Branton PE.

J Virol. 1994 Feb;68(2):776-86.


Uptake and transport of fluorescent derivatives of dolichol in human fibroblasts.

Jiang LW, Mitchell BA, Teodoro JG, Rip JW.

Biochim Biophys Acta. 1993 Apr 22;1147(2):205-13.


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