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Acquisition of Plasmid with Carbapenem-Resistance Gene blaKPC2 in Hypervirulent Klebsiella pneumoniae, Singapore.

Chen Y, Marimuthu K, Teo J, Venkatachalam I, Cherng BPZ, De Wang L, Prakki SRS, Xu W, Tan YH, Nguyen LC, Koh TH, Ng OT, Gan YH.

Emerg Infect Dis. 2020 Mar;26(3):549-559. doi: 10.3201/eid2603.191230.


Sporadic meningioangiomatosis presenting as a middle cranial fossa arachnoid cyst.

Chan BY, Merchant KZ, Teo JG, Chang KT, Low DC, Low SY.

World Neurosurg. 2020 Feb 14. pii: S1878-8750(20)30318-1. doi: 10.1016/j.wneu.2020.02.043. [Epub ahead of print] No abstract available.


Multidrug-resistant Salmonella enterica serovar London carrying blaNDM-1 encoding plasmid from Singapore.

Octavia S, Chew KL, Lee Chew K, Lin RTP, Teo JWP.

Clin Microbiol Infect. 2020 Feb 5. pii: S1198-743X(20)30060-4. doi: 10.1016/j.cmi.2020.01.033. [Epub ahead of print] No abstract available.


Effect of remote ischemic preConditioning on liver injury in patients undergoing liver resection: the ERIC-LIVER trial.

Teo JY, Ho AFW, Bulluck H, Gao F, Chong J, Koh YX, Tan EK, Abdul Latiff JB, Chua SH, Goh BKP, Chan CY, Chung AYF, Lee SY, Cheow PC, Ooi LLPJ, Davidson BR, Jevaraj PR, Hausenloy DJ.

HPB (Oxford). 2020 Jan 29. pii: S1365-182X(19)33218-6. doi: 10.1016/j.hpb.2019.12.002. [Epub ahead of print]


Filling the Gap: A Correlation between Objective and Subjective Measures of Injectability.

Robinson TE, Hughes EAB, Bose A, Cornish EA, Teo JY, Eisenstein NM, Grover LM, Cox SC.

Adv Healthc Mater. 2020 Jan 24:e1901521. doi: 10.1002/adhm.201901521. [Epub ahead of print]


Recovery of Lactobacillus casei strain Shirota (LcS) from faeces of healthy Singapore adults after intake of fermented milk.

Khine WWT, Ang XJ, Chan YS, Lee WQ, Quek SY, Tan SH, Teo HTA, Teo JKB, Lau QC, Lee YK.

Benef Microbes. 2019 Oct 14;10(7):721-728. doi: 10.3920/BM2018.0173. Epub 2019 Jul 24.


Effect of exercise prehabilitation on functional status of patients undergoing bowel resection: a systematic review.

Teo JYK, Turner R, Self M.

ANZ J Surg. 2020 Jan 20. doi: 10.1111/ans.15659. [Epub ahead of print] Review.


Determining the Development of Persisters in Extensively Drug-Resistant Acinetobacter baumannii upon Exposure to Polymyxin B-Based Antibiotic Combinations Using Flow Cytometry.

Wong FH, Cai Y, Leck H, Lim TP, Teo JQ, Lee W, Koh TH, Tan TT, Tan KW, Kwa AL.

Antimicrob Agents Chemother. 2020 Feb 21;64(3). pii: e01712-19. doi: 10.1128/AAC.01712-19. Print 2020 Feb 21.


Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data.

Bean DM, Teo J, Wu H, Oliveira R, Patel R, Bendayan R, Shah AM, Dobson RJB, Scott PA.

PLoS One. 2019 Nov 25;14(11):e0225625. doi: 10.1371/journal.pone.0225625. eCollection 2019.


Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis.

Pasea L, Chung SC, Pujades-Rodriguez M, Shah AD, Alvarez-Madrazo S, Allan V, Teo JT, Bean D, Sofat R, Dobson R, Banerjee A, Patel RS, Timmis A, Denaxas S, Hemingway H.

BMC Med. 2019 Nov 20;17(1):206. doi: 10.1186/s12916-019-1438-y.


Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes.

Tran C, Heng B, Teo JD, Humphrey SJ, Qi Y, Couttas TA, Stefen H, Brettle M, Fath T, Guillemin GJ, Don AS.

J Neurochem. 2019 Nov 19:e14917. doi: 10.1111/jnc.14917. [Epub ahead of print]


Identification of AbaR4 Acinetobacter baumannii resistance island in clinical isolates of blaOXA-23-positive Proteus mirabilis.

Octavia S, Xu W, Ng OT, Marimuthu K, Venkatachalam I, Cheng B, Lin RTP, Teo JWP.

J Antimicrob Chemother. 2020 Mar 1;75(3):521-525. doi: 10.1093/jac/dkz472.


Survival Advantage of Laparoscopic Versus Open Resection For Colorectal Liver Metastases: A Meta-analysis of Individual Patient Data From Randomized Trials and Propensity-score Matched Studies.

Syn NL, Kabir T, Koh YX, Tan HL, Wang LZ, Chin BZ, Wee I, Teo JY, Tai BC, Goh BKP.

Ann Surg. 2019 Oct 22. doi: 10.1097/SLA.0000000000003672. [Epub ahead of print]


Effect of surgical delay on survival outcomes in patients undergoing curative resection for primary hepatocellular carcinoma: Inverse probability of treatment weighting using propensity scores and propensity score adjustment.

Kabir T, Syn N, Ramkumar M, Yeo EYJ, Teo JY, Koh YX, Lee SY, Cheow PC, Chow PKH, Chung AYF, Ooi LL, Chan CY, Goh BKP.

Surgery. 2020 Feb;167(2):417-424. doi: 10.1016/j.surg.2019.09.022. Epub 2019 Oct 31.


Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore.

Ivan FX, Zhou X, Lau SH, Rashid S, Teo JSM, Lee HK, Koay ES, Chan KP, Leo YS, Chen MIC, Kwoh CK, Chow VT.

Int J Infect Dis. 2020 Jan;90:84-96. doi: 10.1016/j.ijid.2019.10.024. Epub 2019 Oct 25.


Inhaled mucoactive particles with tailored architecture for enhanced aerodynamicity, stability and efficacy.

Lee SH, Heng D, Teo JWP, Toh FKY, Tan RBH.

Int J Pharm. 2019 Dec 15;572:118740. doi: 10.1016/j.ijpharm.2019.118740. Epub 2019 Oct 21.


Oral vs Intravenous Antibiotics for Patients With Klebsiella pneumoniae Liver Abscess: A Randomized, Controlled Noninferiority Study.

Molton JS, Chan M, Kalimuddin S, Oon J, Young BE, Low JG, Salada BMA, Lee TH, Wijaya L, Fisher DA, Izharuddin E, Koh TH, Teo JWP, Krishnan PU, Tan BP, Woon WWL, Ding Y, Wei Y, Phillips R, Moorakonda R, Yuen KH, Cher BP, Yoong J, Lye DC, Archuleta S.

Clin Infect Dis. 2019 Oct 23. pii: ciz881. doi: 10.1093/cid/ciz881. [Epub ahead of print]


Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.

Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, Garner B, Ittner A, Karl T, Don AS.

J Neurosci. 2019 Nov 27;39(48):9645-9659. doi: 10.1523/JNEUROSCI.0524-19.2019. Epub 2019 Oct 22.


Neutralisation rate controls the self-assembly of pH-sensitive surfactants.

Hayward DW, Chiappisi L, Teo JH, Prévost S, Schweins R, Gradzielski M.

Soft Matter. 2019 Oct 30;15(42):8611-8620. doi: 10.1039/c9sm00950g.


Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.

Teo JX, Davila S, Yang C, Hii AA, Pua CJ, Yap J, Tan SY, Sahlén A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK, Tan P, Lim WK.

Commun Biol. 2019 Oct 4;2:361. doi: 10.1038/s42003-019-0605-1. eCollection 2019.


Candida auris in Singapore: Genomic epidemiology, antifungal drug resistance, and identification using the updated 8.01 VITEK2 system.

Tan YE, Teo JQ, Rahman NBA, Ng OT, Kalisvar M, Tan AL, Koh TH, Ong RTH.

Int J Antimicrob Agents. 2019 Dec;54(6):709-715. doi: 10.1016/j.ijantimicag.2019.09.016. Epub 2019 Oct 7.


Changing trends and outcomes associated with the adoption of minimally invasive pancreatic surgeries: A single institution experience with 150 consecutive procedures in Southeast Asia.

Goh BK, Low TY, Koh YX, Lee SY, Teo JY, Kam JH, Jeyaraj PR, Cheow PC, Chow PK, Ooi LL, Chung AY, Chan CY.

J Minim Access Surg. 2019 Oct 1. doi: 10.4103/jmas.JMAS_127_19. [Epub ahead of print]


Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.

Ooi WF, Nargund AM, Lim KJ, Zhang S, Xing M, Mandoli A, Lim JQ, Ho SWT, Guo Y, Yao X, Lin SJ, Nandi T, Xu C, Ong X, Lee M, Tan AL, Lam YN, Teo JX, Kaneda A, White KP, Lim WK, Rozen SG, Teh BT, Li S, Skanderup AJ, Tan P.

Gut. 2019 Sep 21. pii: gutjnl-2018-317612. doi: 10.1136/gutjnl-2018-317612. [Epub ahead of print]


CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer.

Ali A, Levantini E, Fhu CW, Teo JT, Clohessy JG, Goggi JL, Wu CS, Chen L, Chin TM, Tenen DG.

Theranostics. 2019 Aug 14;9(21):6157-6174. doi: 10.7150/thno.35805. eCollection 2019.


Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST.

Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18.


Critical Appraisal of the Impact of the Systematic Adoption of Advanced Minimally Invasive Hepatobiliary and Pancreatic Surgery on the Surgical Management of Mirizzi Syndrome.

Koh YX, Basu P, Liew YX, Teo JY, Kam JH, Lee SY, Cheow PC, Jeyaraj P, Chow PKH, Chung AYF, Ooi LLPJ, Chan CY, Goh BKP.

World J Surg. 2019 Dec;43(12):3138-3152. doi: 10.1007/s00268-019-05164-y.


Klebsiella pneumoniae and Klebsiella quasipneumoniae define the population structure of blaKPC-2Klebsiella: a 5 year retrospective genomic study in Singapore.

Octavia S, Kalisvar M, Venkatachalam I, Ng OT, Xu W, Sridatta PSR, Ong YF, Wang L, Chua A, Cheng B, Lin RTP, Teo JWP.

J Antimicrob Chemother. 2019 Nov 1;74(11):3205-3210. doi: 10.1093/jac/dkz332.


Outcome of minimally-invasive versus open pancreatectomies for solid pseudopapillary neoplasms of the pancreas: A 2:1 matched case-control study.

Tan HL, Tan EK, Teo JY, Kam JH, Lee SY, Cheow PC, Jeyaraj PR, Chow PK, Chung AY, Ooi LL, Chan CY, Goh BKP.

Ann Hepatobiliary Pancreat Surg. 2019 Aug;23(3):252-257. doi: 10.14701/ahbps.2019.23.3.252. Epub 2019 Aug 30.


Indirect state-of-charge determination of all-solid-state battery cells by X-ray diffraction.

Bartsch T, Kim AY, Strauss F, de Biasi L, Teo JH, Janek J, Hartmann P, Brezesinski T.

Chem Commun (Camb). 2019 Sep 17;55(75):11223-11226. doi: 10.1039/c9cc04453a.


Putting Time in Perspective: An Integrated Graduate Medical Education Institutional Dashboard and Report Card.

Andrada J, Teo J, Neo J, Yeo H, Leng LB.

J Grad Med Educ. 2019 Aug;11(4 Suppl):169-176. doi: 10.4300/JGME-D-18-00482.


Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells.

Tan YJ, Ali A, Tee SY, Teo JT, Xi Y, Go ML, Lam Y.

Eur J Med Chem. 2019 Nov 15;182:111597. doi: 10.1016/j.ejmech.2019.111597. Epub 2019 Aug 6.


Liver Resection for Nonalcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma.

Koh YX, Tan HJ, Liew YX, Syn N, Teo JY, Lee SY, Goh BKP, Goh GBB, Chan CY.

J Am Coll Surg. 2019 Nov;229(5):467-478.e1. doi: 10.1016/j.jamcollsurg.2019.07.012. Epub 2019 Aug 6.


Antecedent Carbapenem Exposure as a Risk Factor for Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae and Carbapenemase-Producing Enterobacteriaceae.

Marimuthu K, Ng OT, Cherng BPZ, Fong RKC, Pada SK, De PP, Ooi ST, Smitasin N, Thoon KC, Krishnan PU, Ang MLT, Chan DSG, Kwa ALH, Deepak RN, Chan YK, Chan YFZ, Huan X, Zaw Linn K, Tee NWS, Tan TY, Koh TH, Lin RTP, Hsu LY, Sengupta S, Paterson DL, Perencevich E, Harbarth S, Teo J, Venkatachalam I; CaPES Study Group.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00845-19. doi: 10.1128/AAC.00845-19. Print 2019 Oct.


In vitro Pharmacodynamics and PK/PD in Animals.

Lee W, Cai Y, Lim TP, Teo J, Chua SC, Kwa AL.

Adv Exp Med Biol. 2019;1145:105-116. doi: 10.1007/978-3-030-16373-0_8. Review.


Early prolonged ambulatory cardiac monitoring in stroke (EPACS): an open-label randomised controlled trial.

Kaura A, Sztriha L, Chan FK, Aeron-Thomas J, Gall N, Piechowski-Jozwiak B, Teo JT.

Eur J Med Res. 2019 Jul 26;24(1):25. doi: 10.1186/s40001-019-0383-8.


The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300.

Lukaszewicz AI, Nguyen C, Melendez E, Lin DP, Teo JL, Lai KKY, Huttner WB, Shi SH, Kahn M.

Cancers (Basel). 2019 Jul 9;11(7). pii: E962. doi: 10.3390/cancers11070962.


The membrane environment of cadherin adhesion receptors: a working hypothesis.

Teo JL, Parton RG, Yap AS.

Biochem Soc Trans. 2019 Aug 30;47(4):985-995. doi: 10.1042/BST20180012. Epub 2019 Jul 5. Review.


Implementation of genomics in medical practice to deliver precision medicine for an Asian population.

Bylstra Y, Davila S, Lim WK, Wu R, Teo JX, Kam S, Lysaght T, Rozen S, Teh BT, Yeo KK, Cook SA, Tan P, Jamuar SS.

NPJ Genom Med. 2019 Jun 7;4:12. doi: 10.1038/s41525-019-0085-8. eCollection 2019. Review.


Preoperative Predictors Including the Role of Inflammatory Indices in Predicting Early Recurrence After Re-resection for Recurrent Hepatocellular Carcinoma.

Guo Y, Chua DW, Koh YX, Lee SY, Cheow PC, Kam JH, Teo JY, Chow PK, Chung AY, Ooi LL, Chan CY, Goh BKP.

World J Surg. 2019 Oct;43(10):2587-2594. doi: 10.1007/s00268-019-05051-6.


Vitamin E analogues differentially inhibit human cytochrome P450 3A (CYP3A)-mediated oxidative metabolism of lithocholic acid: Impact of δ-tocotrienol on lithocholic acid cytotoxicity.

Wong SY, Teo JSM, Chai SF, Yeap SL, Lau AJ.

Toxicology. 2019 Jul 1;423:62-74. doi: 10.1016/j.tox.2019.05.005. Epub 2019 May 15.


Challenge of drug resistance in Pseudomonas aeruginosa: clonal spread of NDM-1-positive ST-308 within a tertiary hospital.

Chew KL, Octavia S, Ng OT, Marimuthu K, Venkatachalam I, Cheng B, Lin RTP, Teo JWP.

J Antimicrob Chemother. 2019 Aug 1;74(8):2220-2224. doi: 10.1093/jac/dkz169.


Impact of spontaneous rupture on the survival outcomes after liver resection for hepatocellular carcinoma: A propensity matched analysis comparing ruptured versus non-ruptured tumors.

Chua DW, Koh YX, Allen JC, Chan CY, Lee SY, Cheow PC, Jeyaraj P, Teo JY, Chow PK, Chung AY, Ooi LL, Goh BKP.

Eur J Surg Oncol. 2019 Sep;45(9):1652-1659. doi: 10.1016/j.ejso.2019.03.044. Epub 2019 Apr 9.


In vivo development of amoxicillin and ceftriaxone resistance in Salmonella enterica serovar Typhi.

Tan GSE, Octavia S, Teo JWP, Ang MLT, La MV, Lin RTP, Choudhury S, Ang BSP.

Clin Microbiol Infect. 2019 Aug;25(8):1045-1047. doi: 10.1016/j.cmi.2019.03.015. Epub 2019 Mar 23. No abstract available.


External validation of the Japanese difficulty scoring system for minimally-invasive distal pancreatectomies.

Goh BKP, Kabir T, Koh YX, Teo JY, Lee SY, Kam JH, Cheow PC, Jeyaraj PR, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Am J Surg. 2019 Nov;218(5):967-971. doi: 10.1016/j.amjsurg.2019.03.012. Epub 2019 Mar 15.


An Artificial Tissue Homeostasis Circuit Designed via Analog Circuit Techniques.

Teo JJY, Weiss R, Sarpeshkar R.

IEEE Trans Biomed Circuits Syst. 2019 Jun;13(3):540-553. doi: 10.1109/TBCAS.2019.2907074. Epub 2019 Mar 25.


Initial single institution experience with robotic biliary surgery and bilio-enteric anastomosis in southeast Asia.

Goh BKP, Low TY, Teo JY, Lee SY, Chan CY, Chung AYF, Ooi LLPJ.

ANZ J Surg. 2019 Apr;89(4):E142-E146. doi: 10.1111/ans.15135. Epub 2019 Mar 18.


Risk factors and outcomes associated with the isolation of polymyxin B and carbapenem-resistant Enterobacteriaceae spp.: A case-control study.

Teo JQ, Chang CW, Leck H, Tang CY, Lee SJ, Cai Y, Ong RT, Koh TH, Tan TT, Kwa AL.

Int J Antimicrob Agents. 2019 May;53(5):657-662. doi: 10.1016/j.ijantimicag.2019.03.011. Epub 2019 Mar 14.


Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.

Lai KKY, Nguyen C, Lee KS, Lee A, Lin DP, Teo JL, Kahn M.

Curr Mol Pharmacol. 2019;12(3):167-183. doi: 10.2174/1874467212666190304121131.


HEXIM1 Peptide Exhibits Antimicrobial Activity Against Antibiotic Resistant Bacteria Through Guidance of Cell Penetrating Peptide.

Ho PL, Ong HK, Teo J, Ow DS, Chao SH.

Front Microbiol. 2019 Feb 8;10:203. doi: 10.3389/fmicb.2019.00203. eCollection 2019.


Surface tethering of stem cells with H2O2-responsive anti-oxidizing colloidal particles for protection against oxidation-induced death.

Teo JY, Seo Y, Ko E, Leong J, Hong YT, Yang YY, Kong H.

Biomaterials. 2019 May;201:1-15. doi: 10.1016/j.biomaterials.2019.01.039. Epub 2019 Feb 13.


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