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Items: 5

1.

The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.

Tenthorey JL, Haloupek N, López-Blanco JR, Grob P, Adamson E, Hartenian E, Lind NA, Bourgeois NM, Chacón P, Nogales E, Vance RE.

Science. 2017 Nov 17;358(6365):888-893. doi: 10.1126/science.aao1140.

2.

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.

Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE.

Immunity. 2017 Apr 18;46(4):649-659. doi: 10.1016/j.immuni.2017.03.016. Epub 2017 Apr 11.

3.

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.

Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, Kazmierczak BI, Vance RE.

J Exp Med. 2016 May 2;213(5):657-65. doi: 10.1084/jem.20151809. Epub 2016 Apr 4.

4.

An E2 accessory domain increases affinity for the anaphase-promoting complex and ensures E2 competition.

Girard JR, Tenthorey JL, Morgan DO.

J Biol Chem. 2015 Oct 2;290(40):24614-25. doi: 10.1074/jbc.M115.678193. Epub 2015 Aug 25.

5.

Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes.

Tenthorey JL, Kofoed EM, Daugherty MD, Malik HS, Vance RE.

Mol Cell. 2014 Apr 10;54(1):17-29. doi: 10.1016/j.molcel.2014.02.018. Epub 2014 Mar 20.

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